Cited by 224Cardiovascular and exercise physiologyPhysical Activity and HealthSports Performance and Training

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Separate effects of intensity and amount of exercise on interindividual cardiorespiratory fitness response.

Ross, Robert, de Lannoy, Louise, Stotz, Paula J.·2015·Mayo Clinic Proceedings

DOI 10.1016/j.mayocp.2015.07.024

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Abstract

Objective To determine the separate effects of exercise intensity and amount on interindividual cardiorespiratory fitness (CRF) response.Participants and methods Participants were 121 (75 females, 62%) sedentary, middle-aged (mean [SD] age, 53.2 [7.5] years), abdominally obese adults who completed at least 90% of 5 weekly exercise sessions prescribed over a 24-week intervention. Participants were randomly assigned to (1) low-amount, low-intensity exercise (LALI) (180 and 300 kcal per session for women and men, respectively, at 50% of CRF [VO 2peak]; n=39), (2) high-amount, low-intensity exercise (HALI) (360 and 600 kcal per session for women and men, respectively, at 50% of CRF; n=51), or high-amount, high-intensity exercise (HAHI) (360 and 600 kcal per session for women and men, respectively, at 75% of CRF; n=31). Cardiorespiratory fitness was measured using a treadmill test at 4, 8, 16, and 24 weeks. The study duration was September 1, 2009, through May 31, 2013.Results Cardiorespiratory fitness increased within all 3 groups at 24 weeks (P<.001). At 24 weeks, 38.5% (15 of 39), 17.6% (9 of 51), and 0% (0 of 31) of the participants within the LALI, HALI, and HAHI groups, respectively, were CRF nonresponders. At a fixed exercise intensity, increasing exercise amount reduced the rate of nonresponse by 50% (P=.02). At a fixed amount of exercise, increasing the exercise intensity eliminated nonresponse (P=.001). Exposure to exercise decreased the number of CRF nonresponders between 4 and 8 weeks for LALI and by 16 weeks for HALI but plateaued thereafter. For HAHI, the number of CRF nonresponders decreased continually over the 24 weeks.Conclusion For a fixed amount of exercise, increasing exercise intensity consistent with consensus recommendations eliminated CRF nonresponse. Low-intensity exercise may not be sufficient to improve CRF for a substantial proportion of sedentary obese adults.

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Authors: Ross, R., de Lannoy, L., & Stotz, P. J.
Affiliations: Queen's University (CA)
Corresponding author: Ross, Robert
ORCID: Ross, Robert
Stotz, Paula J.
Venue: Mayo Clinic Proceedings
Publisher: Elsevier BV
Published: 2015-11
Volume: 90
Issue: 11
Pages: 1506-1514
ISSN: 0025-6196 (ISSN-L)
DOI: 10.1016/j.mayocp.2015.07.024
OpenAlex: W2100550631
Cited by: 224
References: 19
Citations by year: 2026: 13 · 2025: 17 · 2024: 26 · 2023: 19 · 2022: 23 · 2021: 24 · 2020: 23 · 2019: 31 · 2018: 22 · 2017: 15 · 2016: 11
FWCI: 31.28
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Mayo Clinic Proceedings (publishedVersion)
PubMed (publishedVersion)
Funders: Canadian Institutes of Health Research
Topics: Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
Keywords: cardiorespiratory fitness, exercise intensity, high-intensity interval training, sedentary adults, abdominal obesity, middle-aged adults, peak oxygen uptake, exercise prescription, sex differences in exercise response, exercise frequency, training duration
MeSH terms: Adult, Exercise Test, Exercise Therapy, Physical Exertion, Female, Humans, Male, Middle Aged, Monitoring, Physiologic, Physical Fitness, Treatment Outcome, Obesity, Abdominal, Sedentary Behavior

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Separate effects of intensity and amount of exercise on interindividual cardiorespiratory fitness response.

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