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Caffeic Acid, a Polyphenolic Micronutrient Rescues Mice Brains against Aβ-Induced Neurodegeneration and Memory Impairment

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Abnormal metabolic processes involved in the pathogenesis of non‑alcoholic fatty liver disease (Review)

Shao, M., Ye, Z., Qin, Y., & Wu, T. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9154 · Cited by 52 · see citing works

The metabolic triad of non‐alcoholic fatty liver disease, visceral adiposity and type 2 diabetes: Implications for treatment

Cariou, B. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14651 · Cited by 52 · see citing works

Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways

Park, J. S., Choe, K., Lee, H. J., Park, T. J., & Kim, M. O. (2023) · Journal of Biomedical Science · doi:10.1186/s12929-023-00961-z · Cited by 51 · see citing works

Lupeol, a Plant-Derived Triterpenoid, Protects Mice Brains against Aβ-Induced Oxidative Stress and Neurodegeneration

Ahmad, R., Khan, A., Lee, H. J., Rehman, I. U., Khan, I., Alam, S. I., & Kim, M. O. (2020) · Biomedicines · doi:10.3390/biomedicines8100380 · Cited by 50 · see citing works

The adiponectin signalling pathway - A therapeutic target for the cardiac complications of type 2 diabetes?

Sharma, A., Mah, M., Ritchie, R. H., & Blasio, M. J. D. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.108008 · Cited by 50 · see citing works

Lupeol Treatment Attenuates Activation of Glial Cells and Oxidative-Stress-Mediated Neuropathology in Mouse Model of Traumatic Brain Injury

Ahmad, R., Khan, A., Rehman, I. U., Lee, H. J., Khan, I., & Kim, M. O. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116086 · Cited by 47 · see citing works

Natural SIRT1 modifiers as promising therapeutic agents for improving diabetic wound healing

Prabhakar, P. K., Singh, K., Kabra, D. G., & Gupta, J. (2020) · Phytomedicine · doi:10.1016/j.phymed.2020.153252 · Cited by 45 · see citing works

Therapeutic efficacy of liraglutide versus metformin in modulating the gut microbiota for treating type 2 diabetes mellitus complicated with nonalcoholic fatty liver disease

Ying, X., Rongjiong, Z., Kahaer, M., Chunhui, J., & Wulasihan, M. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1088187 · Cited by 47 · see citing works

Effects of sodium-glucose co-transporter-2 (SGLT2) inhibitors on non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Ex quo et quo vadimus?

Katsiki, N., Perakakis, N., & Mantzoros, C. S. (2019) · Metabolism · doi:10.1016/j.metabol.2019.07.009 · Cited by 36 · see citing works

Lupeol protect against LPS-induced neuroinflammation and amyloid beta in adult mouse hippocampus

Choe, K., Park, J. S., Park, H. Y., Tahir, M., Park, T. J., & Kim, M. O. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1414696 · Cited by 34 · see citing works

Regeneration during Obesity: An Impaired Homeostasis

Ghanemi, A., Yoshioka, M., & St‐Amand, J. (2020) · Animals · doi:10.3390/ani10122344 · Cited by 27 · see citing works

Targeting adipokines in polycystic ovary syndrome and related metabolic disorders: from experimental insights to clinical studies

Xu, Y., Zhu, H., Li, W., Chen, D., Xu, Y., Xu, A., & Ye, D. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108284 · Cited by 30 · see citing works

Nuclear receptors and non-alcoholic fatty liver disease: An update

Xiao, Y., Gonzalez, F. J., Huang, M., & Bi, H. (2020) · Liver Research · doi:10.1016/j.livres.2020.03.001 · Cited by 29 · see citing works

Prevention of Nonalcoholic Hepatic Steatosis by Shenling Baizhu Powder: Involvement of Adiponectin-Induced Inhibition of Hepatic SREBP-1c

Tang, K., Deng, Y., Zheng, C., Nie, H., Pan, M., Chen, R., Xie, J., Yang, Q., & Zhang, Y. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/9701285 · Cited by 28 · see citing works

4‐O‐methylhonokiol protects against diabetic cardiomyopathy in type 2 diabetic mice by activation of AMPK‐mediated cardiac lipid metabolism improvement

Zheng, Z., Ma, T., Guo, H., Kim, K. S., Kim, K., Bi, L., Zhang, Z., & Cai, L. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14493 · Cited by 25 · see citing works

Imbalance of Drug Transporter-CYP450s Interplay by Diabetes and Its Clinical Significance

Yang, Y., & Liu, X. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12040348 · Cited by 24 · see citing works

The Long Noncoding RNA Blnc1 Protects Against Diet-Induced Obesity by Promoting Mitochondrial Function in White Fat

Tang, S., Zhu, W., Zheng, F., Gui, W., Zhang, W., Lin, X., & Li, H. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s248692 · Cited by 23 · see citing works

Obese Animals as Models for Numerous Diseases: Advantages and Applications

Ghanemi, A., Yoshioka, M., & St‐Amand, J. (2021) · Medicina · doi:10.3390/medicina57050399 · Cited by 23 · see citing works

Adiponectin homolog osmotin, a potential anti-obesity compound, suppresses abdominal fat accumulation in C57BL/6 mice on high-fat diet and in 3T3-L1 adipocytes

Jo, M. G., Kim, M. W., Jo, M. H., Abid, N. B., & Kim, M. O. (2019) · International Journal of Obesity · doi:10.1038/s41366-019-0383-3 · Cited by 21 · see citing works

O-Cyclic Phytosphingosine-1-Phosphate Protects against Motor Dysfunctions and Glial Cell Mediated Neuroinflammation in the Parkinson’s Disease Mouse Models

Lee, H. J., Choe, K., Park, J. S., Khan, A., Kim, M. W., Park, T. J., & Kim, M. O. (2022) · Antioxidants · doi:10.3390/antiox11112107 · Cited by 20 · see citing works

CSAD Ameliorates Lipid Accumulation in High-Fat Diet-Fed Mice

Tan, R., Li, J., Liu, L., Wu, Q., Fan, L., Ma, N., Yu, C., Lu, H., Zhang, X., Chen, J., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415931 · Cited by 19 · see citing works

Tectorigenin protects against cardiac fibrosis in diabetic mice heart via activating the adiponectin receptor 1-mediated AMPK pathway

Ma, Y., Xu, M., Cen, X.-F., Qiu, H.-L., Guo, Y., & Tang, Q. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116589 · Cited by 19 · see citing works

Gut Microbiota Composition and Structure of the Ob/Ob and Db/Db Mice

Yang, M., Liu, Y., Xie, H., Wen, Z., Zhang, Y., Wu, C., Huang, L., Wu, J., Xie, C., Wang, T., et al. (2019) · International Journal of Endocrinology · doi:10.1155/2019/1394097 · Cited by 19 · see citing works

Organophosphorus Flame Retardants and Metabolic Disruption: An in Silico , in Vitro , and in Vivo Study Focusing on Adiponectin Receptors

Liu, Y., Ma, X., Le, Y., Feng, J., Xu, M., Wang, W., & Wang, C. (2024) · Environmental Health Perspectives · doi:10.1289/ehp14634 · Cited by 18 · see citing works

Transcriptome responses in blood reveal distinct biological pathways associated with arsenic exposure through drinking water in rural settings of Punjab, Pakistan

Rehman, M. Y. A., van Herwijnen, M. H. M., Krauskopf, J., Farooqi, A., Kleinjans, J. C. S., Malik, R. N., & Briedé, J. J. (2019) · Environment International · doi:10.1016/j.envint.2019.105403 · Cited by 18 · see citing works

Cloning and characterization of KoOsmotin from mangrove plant Kandelia obovata under cold stress

Jiao, F., Wang, Y., Cheng, H., Su, Y., Zhong, Y., & Zheng, L. (2021) · BMC Plant Biology · doi:10.1186/s12870-020-02746-0 · Cited by 18 · see citing works

Role of Adiponectin Receptor 1 in Promoting Nitric Oxide-Mediated Flow-Induced Dilation in the Human Microvasculature

Cohen, K. E., Katunaric, B., Schulz, M. E., SenthilKumar, G., Young, M. S., Mace, J. E., & Freed, J. K. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.875900 · Cited by 17 · see citing works

Association between lower plasma adiponectin levels and higher liver stiffness in type 2 diabetic individuals with nonalcoholic fatty liver disease: an observational cross-sectional study

Mantovani, A., Zusi, C., Csermely, A., Salvagno, G. L., Colecchia, A., Lippi, G., Maffeis, C., & Targher, G. (2022) · HORMONES · doi:10.1007/s42000-022-00387-6 · Cited by 16 · see citing works

Impact of Incretin-Based Therapies on Adipokines and Adiponectin

Yaribeygi, H., Maleki, M., Atkin, S. L., Jamialahmadi, T., & Sahebkar, A. (2021) · Journal of Diabetes Research · doi:10.1155/2021/3331865 · Cited by 15 · see citing works

Effects of Hydroxycitric Acid Supplementation on Body Composition, Obesity Indices, Appetite, Leptin, and Adiponectin of Women with NAFLD on a Calorie-Restricted Diet

Tutunchi, H., Arefhosseini, S., Nomi-Golzar, S., & Ebrahimi‐Mameghani, M. (2023) · International Journal of Clinical Practice · doi:10.1155/2023/6492478 · Cited by 12 · see citing works

Metagenomic and metabolomic analyses show correlations between intestinal microbiome diversity and microbiome metabolites in ob/ob and ApoE−/− mice

Dong, S., Wu, C., He, W., Zhong, R., Deng, J., Tao, Y., Zha, F.-R., Liao, Z., Fang, X., & Wei, H. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.934294 · Cited by 12 · see citing works

Overview of a novel osmotin abolishes abnormal metabolic-associated adiponectin mechanism in Alzheimer’s disease: Peripheral and CNS insights

Rehman, I. U., Park, J. S., Choe, K., Park, H. Y., Park, T. J., & Kim, M. O. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102447 · Cited by 11 · see citing works

Collagen β(1-O) galactosyltransferase 2 deficiency contributes to lipodystrophy and aggravates NAFLD related to HMW adiponectin in mice

Yang, J., He, L., Gao, M., Xiao, F., Zhang, F., Wang, S., Yang, S., Ye, X., Qu, W., Li, L., et al. (2021) · Metabolism · doi:10.1016/j.metabol.2021.154777 · Cited by 10 · see citing works

ROS Dependent Antifungal and Anticancer Modulations of Piper colubrinum Osmotin

Geetha, R. G., Chandrika, S. K., Saraswathy, G. G., Sivakumari, A. N., & Sakuntala, M. (2021) · Molecules · doi:10.3390/molecules26082239 · Cited by 9 · see citing works

Polycystic ovary syndrome and nonalcoholic fatty liver disease

Georgescu, C. E. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823045-9.00007-9 · Cited by 9 · see citing works

Low-dose alcohol ameliorated high fat diet-induced anxiety-related behavior via enhancing adiponectin expression and activating the Nrf2 pathway

Cheng, J., Zhang, M., Cheng, S., Li, F., Zhang, B., Sun, X., Hu, H., Chen, L., Zhao, Z., Hu, H., et al. (2020) · Food & Function · doi:10.1039/d0fo02704a · Cited by 8 · see citing works

Celastrol attenuates HFD-induced obesity and improves metabolic function independent of adiponectin signaling

Ye, L., Gao, Y., Li, X., Liang, X., Yang, Y., & Zhang, R. (2023) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2023.2250929 · Cited by 7 · see citing works

Exercise-promoted adiponectin secretion activates autolysosomes to protect the liver of ApoE −/− mice from a high-fat diet

Wu, W., Ye, J., Yuan, S., Li, X., Tang, Y., Zeng, F., Liu, W., Zhao, Z., Wang, Y., Wang, Y., et al. (2024) · Food & Function · doi:10.1039/d4fo02984d · Cited by 7 · see citing works

Synbiotic Supplementation Modulates Gut Microbiota, Regulates β-Catenin Expression and Prevents Weight Gain in ob/ob Mice: Preliminary Findings

Duarte, S. M., Stefano, J., Franco, L. A., Martins, R. C., Moraes, B. D. G. C., Barbeiro, D., Oliveira, N., Neri, J., Cogliati, B., Vanni, D., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810483 · Cited by 5 · see citing works

Metabolism updates: new directions, techniques, and exciting research that is broadening the horizons

Boutari, C., Bouzoni, E., Joshi, A., Stefanakis, K., Farr, O. M., & Mantzoros, C. S. (2019) · Metabolism · doi:10.1016/j.metabol.2019.154009 · Cited by 6 · see citing works

Showing NAFLD, as a key connector disease between Alzheimer's disease and diabetes via analysis of systems biology.

Gholizadeh, E., Khaleghian, A., Seyfi, D. N., & Karbalaei, R. (2020) · Gastroenterology and hepatology from bed to bench. · Cited by 6 · see citing works

Adiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons

McGregor, E. R., Osterbauer, K. J., Gustafson, G. E., Clark, J. P., Rhoads, T. W., & Anderson, R. M. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103059 · Cited by 6 · see citing works

Mild hypothermia attenuates hepatic ischemia-reperfusion injury by regulating FoxO1/PPARα pathway

Lu, Z., Chen, H., Liu, A., Na, S., Wang, W., Zhong, Z., & Ye, Q. (2025) · Scientific Reports · doi:10.1038/s41598-025-09725-1 · Cited by 4 · see citing works

The Immune System and Inflammation in Type 2 Diabetes

García-Macedo, R., & Fortis, M. D. L. Á. (2023) · Springer eBooks · doi:10.1007/978-3-031-25519-9_12 · Cited by 5 · see citing works

Revitalizing gut barrier integrity: role of miR-192-5p in enhancing autophagy via Rictor in enteritis

Qiu, P., Zhou, K., Wang, Y., Chen, X., Xiao, C., Li, W., Chen, Y., Chang, Y., Liu, J., Zhou, F., et al. (2024) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00291.2023 · Cited by 3 · see citing works

Emerging multi-target strategies and dual agonists of PPAR-α/γ modulation in Type 2 diabetes

Arora, P., Tyagi, A., Kumar, V., Arulsamy, S., Kaushik, M., & Kumar, S. (2026) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2026.146281 · Cited by 2 · see citing works

Adiponectin and central nervous system disorders: Regulatory mechanisms and therapeutic potential

Li, M., Wu, M., Gao, H., Xue, X., Xiao, W., & Zhu, L. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108260 · Cited by 2 · see citing works

Adiponectin-enhancing dietary constituents in cancer prevention

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Obez Sıçanlarda Selenyum ve N-Asetil Sistein’in Fertilite/ İnfertilite ve Karaciğer Üzerine Etkisi

Başaran, G., Gökçımen, A., Can, N. K., & Kabaoğlu, U. (2022) · Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi · doi:10.47572/muskutd.725703

PSORIAZĖS IR METABOLINIO SINDROMO SĄSAJOS IR BENDRI PATOFIZIOLOGIJOS MECHANIZMAI

Vrublevski, M. (2024) · Health Sciences · doi:10.35988/sm-hs.2024.100

Additional file 1 of Adiponectin-mimetic novel nonapeptide rescues aberrant neuronal metabolic-associated memory deficits in Alzheimer’s disease

Ali, T., Rehman, S. U., Khan, A., Badshah, H., Abid, N. B., Kim, M. W., Jo, M. H., Chung, S. S., Lee, H.-G., Rutten, B. P. F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14411201

Additional file 1 of Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways

Park, J. S., Choe, K., Lee, H. J., Park, T. J., & Kim, M. O. (2023) · Figshare · doi:10.6084/m9.figshare.23935809

Anti-obesity potential of a latex-derived bioactive peptide fraction from Calotropis procera: Depot-selective fat reduction and systemic metabolic improvement in high-fat diet-fed micePreprint

Gaban, S. V. F., Ramos, M., de Alencar, N. M. N., & da Silva, A. A. (2026) · Research Square · doi:10.21203/rs.3.rs-10732569/v1

Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease

Ishtiaq, S. M., Rashid, H., Hussain, Z., Arshad, M. I., & Khan, J. A. (2019) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-019-09510-2 · Cited by 66 · see citing works

What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?

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The role of adiponectin in the pathogenesis and treatment of non‐alcoholic fatty liver disease

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Adiponectin homolog osmotin, a potential anti-obesity compound, suppresses abdominal fat accumulation in C57BL/6 mice on high-fat diet and in 3T3-L1 adipocytes

Jo, M. G., Kim, M. W., Jo, M. H., Abid, N. B., & Kim, M. O. (2019) · International Journal of Obesity · doi:10.1038/s41366-019-0383-3 · Cited by 21 · see citing works

Reduced Adiponectin Signaling Due to Weight Gain Results in Nonalcoholic Steatohepatitis Through Impaired Mitochondrial Biogenesis

Handa, P., Maliken, B. D., Nelson, J. E., Morgan‐Stevenson, V., Messner, D. J., Dhillon, B. K., Klintworth, H. M., Beauchamp, M. D., Yeh, M. M., Elfers, C., et al. (2013) · Hepatology · doi:10.1002/hep.26946 · Cited by 95 · see citing works