c-Myc Regulates Transcriptional Pause Release

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

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Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

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The landscape of somatic copy-number alteration across human cancers

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

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Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

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Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells

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Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

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A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells

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Reflecting on 25 years with MYC

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Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast

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Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

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An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

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A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

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Transcriptional activation by recruitment

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Controlling the elongation phase of transcription with P-TEFb

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Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcriptionPreprint

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Myc’s broad reach

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The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

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Divergent transcription from active promoters

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A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

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NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation

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Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

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MicroRNA Let-7a Down-regulates MYC and Reverts MYC-Induced Growth in Burkitt Lymphoma Cells

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

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RNA polymerase is poised for activation across the genome

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LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism

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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

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Chromatin immunoprecipitation and microarray-based analysis of protein location

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The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation

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The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged

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Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase

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Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

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Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo

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Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells

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Defining mechanisms that regulate RNA polymerase II transcription in vivo

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Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive Elongation

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5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase IIPreprint

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Identification of multiple cyclin subunits of human P-TEFb.Preprint

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Phosphorylation of Serine 2 within the RNA Polymerase II C-Terminal Domain Couples Transcription and 3′ End Processing

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Breaking barriers to transcription elongation

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c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription

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Flavopiridol Inhibits P-TEFb and Blocks HIV-1 Replication

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NF-κB Binds P-TEFb to Stimulate Transcriptional Elongation by RNA Polymerase II

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Low molecular weight inhibitors of Myc–Max interaction and function

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P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation.

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Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II

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Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal

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RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes

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NELF and DSIF cause promoter proximal pausing on thehsp70promoter inDrosophilaPreprint

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P-TEFb kinase recruitment and function at heat shock lociPreprint

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Exchange of RNA Polymerase II Initiation and Elongation Factors during Gene Expression In Vivo

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NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assemblyPreprint

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Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.Preprint

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High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongationPreprint

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Myc Recruits P-TEFb to Mediate the Final Step in the Transcriptional Activation of the cad Promoter

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p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

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Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expressionPreprint

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Coordination of Transcription, RNA Processing, and Surveillance by P-TEFb Kinase on Heat Shock Genes

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The human PAF complex coordinates transcription with events downstream of RNA synthesisPreprint

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Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc

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Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells

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c-Myc Mediates Activation of the cad Promoter via a Post-RNA Polymerase II Recruitment Mechanism

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Transcription elongation factor hSPT5 stimulates mRNA cappingPreprint

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Positive Transcription Elongation Factor b Phosphorylates hSPT5 and RNA Polymerase II Carboxyl-terminal Domain Independently of Cyclin-dependent Kinase-activating Kinase

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The Transition between Transcriptional Initiation and Elongation in E. coli Is Highly Variable and Often Rate Limiting

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Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II

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Improved low molecular weight Myc-Max inhibitors

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MYC-Dependent Regulation and Prognostic Role of CIP2A in Gastric Cancer

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Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells

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Dissecting Oct3/4-Regulated Gene Networks in Embryonic Stem Cells by Expression Profiling

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Structural Rationale for the Coupled Binding and Unfolding of the c-Myc Oncoprotein by Small Molecules

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The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.Preprint

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c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis

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Properties of RNA Polymerase II Elongation Complexes Before and After the P-TEFb-mediated Transition into Productive Elongation

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P-TEFb Is Critical for the Maturation of RNA Polymerase II into Productive Elongation In Vivo

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Gene function in early mouse embryonic stem cell differentiation

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Poised RNA Polymerase II Gives Pause for Thought

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Poised Polymerases: On Your Mark…Get Set…Go!

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RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene.

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Drosophila Paf1 Modulates Chromatin Structure at Actively Transcribed Genes

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The transition from transcriptional initiation to elongation

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A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFbPreprint

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P-TEFb is a Crucial Co-Factor for Myc Transactivation

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Tax Interacts with P-TEFb in a Novel Manner To Stimulate Human T-Lymphotropic Virus Type 1 Transcription

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Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

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The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

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Fine-tuning of the intracellular canonical Notch signaling pathway

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