The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Remodeling of Yeast Genome Expression in Response to Environmental Changes
Open accessAbstract
We used genome-wide expression analysis to explore how gene expression in Saccharomyces cerevisiae is remodeled in response to various changes in extracellular environment, including changes in temperature, oxidation, nutrients, pH, and osmolarity. The results demonstrate that more than half of the genome is involved in various responses to environmental change and identify the global set of genes induced and repressed by each condition. These data implicate a substantial number of previously uncharacterized genes in these responses and reveal a signature common to environmental responses that involves ∼10% of yeast genes. The results of expression analysis with MSN2/MSN4 mutants support the model that the Msn2/Msn4 activators induce the common response to environmental change. These results provide a global description of the transcriptional response to environmental change and extend our understanding of the role of activators in effecting this response.
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Cites
Cluster analysis and display of genome-wide expression patterns
Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 16,184
Hsp90 as a capacitor for morphological evolution
Rutherford, S. L., & Lindquist, S. (1998) · Nature · doi:10.1038/24550 · Cited by 2,270
Borkovich, K. A., Farrelly, F. W., Finkelstein, D. B., Taulien, J., & Lindquist, S. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.9.3919 · Cited by 641
Global response of Saccharomyces cerevisiae to an alkylating agent
Jelinsky, S. A., & Samson, L. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1486 · Cited by 419 · cited 4×
“A transient reduction in the synthesis of ribosomal protein mRNAs would permit energy and other resources to be diverted toward the synthesis and use of molecular chaperones, along with other mechanisms involved in surviving a change in the environment (Jelinsky and Samson, 1999).”
BackgroundMethodInfluentialDuina, A. A., Kalton, H. M., & Gaber, R. F. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.18974 · Cited by 143 · cited 1×
“In the absence of heat shock, Hsf1 is inactive; the molecular chaperone Hsp90 is thought to contribute to this inactivation by binding and sequestering the activator (Ali et al., 1998; Duina et al., 1998; Zou et al., 1998; Bharadwaj et al., 1999).”
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Cited by
Reactive oxygen species: Metabolism, oxidative stress, and signal transduction
Apel, K., & Hirt, H. (2004) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.55.031903.141701 · Cited by 11,723
Functional profiling of the Saccharomyces cerevisiae genome
Giaever, G., Chu, A. M., Ni, L., Connelly, C., Riles, L., Véronneau, S., Dow, S., Lucau-Danila, A., Anderson, K., André, B., et al. (2002) · Nature · doi:10.1038/nature00935 · Cited by 4,316
Transcriptional Regulatory Networks in Saccharomyces cerevisiae
Lee, T. I., Rinaldi, N. J., Robert, F., Odom, D. T., Bar-Joseph, Z., Gerber, G. K., Hannett, N. M., Harbison, C. T., Thompson, C. M., Simon, I., et al. (2002) · Science · doi:10.1126/science.1075090 · Cited by 2,956
Self-citationOsmotic Stress Signaling and Osmoadaptation in Yeasts
Hohmann, S. (2002) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.66.2.300-372.2002 · Cited by 1,767
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
López-Maury, L., Marguerat, S., & Bähler, J. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2398 · Cited by 1,061
Metadata
- Authors
- Causton, H. C., Ren, B., Koh, S. S., Harbison, C. T., Kanin, E., Jennings, E. G., Lee, T. I., True, H. L., Lander, E. S., & Young, R. A.
- Venue
- Molecular Biology of the Cell
- Published
- 2001-02
- Volume
- 12
- Issue
- 2
- Pages
- 323-337
- ISSN
- 1059-1524 (ISSN-L)
- 1939-4586
- OpenAlex
- W2127754721
- Cited by
- 1,370
- References
- 5
- FWCI
- 24.97
- Type
- journal article
- Language
- en
- Open access
- green
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- Causton, H. C., Ren, B., Koh, S. S., Harbison, C. T., Kanin, E., Jennings, E. G., Lee, T. I., True, H. L., Lander, E. S., & Young, R. A. (2001). Remodeling of Yeast Genome Expression in Response to Environmental Changes. Molecular Biology of the Cell. https://doi.org/10.1091/mbc.12.2.323
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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