p53 engages the cGAS/STING cytosolic DNA sensing pathway for tumor suppression

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cGAS-STING at the crossroads in cancer therapy

Wang, R., Hussain, A., Guo, Q., & Ma, M. (2023) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2023.104194 · Cited by 26 · see citing works

At the Crossroads of the cGAS-cGAMP-STING Pathway and the DNA Damage Response: Implications for Cancer Progression and Treatment

Korneenko, T. V., Pestov, N. B., Nevzorov, I. A., Daks, A. A., Николаевич, Т. К., Солопова, О. Н., & Barlev, N. A. (2023) · Pharmaceuticals · doi:10.3390/ph16121675 · Cited by 28 · see citing works

Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice

Wu, Y., Zhang, Y., Yu, Y., Wang, X., Zhen, Z., Yuan, Y., Xie, B., Han, M., Wang, M., Zhang, X., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-62181-3 · Cited by 30 · see citing works

Roles of p53-Mediated Host–Virus Interaction in Coronavirus Infection

Wang, X., Liu, Y., Li, K., & Hao, Z. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076371 · Cited by 27 · see citing works

DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling

Wheeler, O. P. G., & Unterholzner, L. (2023) · Essays in Biochemistry · doi:10.1042/ebc20220241 · Cited by 26 · see citing works

The multiple faces of cGAS-STING in antitumor immunity: prospects and challenges

Zhou, Z., Huang, S., Fan, F., Xu, Y., Moore, C., Li, S., & Han, C. (2024) · Medical Review · doi:10.1515/mr-2023-0061 · Cited by 25 · see citing works

Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8 + T-cell antitumor activity via the non-canonical P53/STING pathway

Wu, J., Liu, N., Chen, J., Tao, Q., Lu, C., Li, Q., Chen, X., & Peng, C. (2025) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2024-010252 · Cited by 24 · see citing works

Permission to pass: on the role of p53 as a gatekeeper for aneuploidy

Marques, J. F., & Kops, G. J. P. L. (2023) · Chromosome Research · doi:10.1007/s10577-023-09741-9 · Cited by 24 · see citing works

Targeting STING signaling for the optimal cancer immunotherapy

Xu, Y., & Xiong, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1482738 · Cited by 22 · see citing works

Cyclic GMP-AMP synthase recognizes the physical features of DNA

Dong, L., Hou, Y.-R., Xu, N., Gao, X., Sun, Z., Yang, Q., & Wang, L. (2024) · Acta Pharmacologica Sinica · doi:10.1038/s41401-024-01369-7 · Cited by 21 · see citing works

STING-Activating Nanoparticles Combined with PD-1/PD-L1 Blockade: A Synergistic Approach in Cancer Immunotherapy

Bartusik‐Aebisher, D., Rogóż, K., & Aebisher, D. (2025) · Biomedicines · doi:10.3390/biomedicines13092160 · Cited by 21 · see citing works

The role of ion channels in T cell function and disease

Manolios, N., Papaemmanouil, J., & Adams, D. J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1238171 · Cited by 20 · see citing works

Mutant p53 Gain of Function: Why Many See It, Why Some Do Not

Lozano, G., Prives, C. L., & Sabapathy, K. (2025) · Cancer Discovery · doi:10.1158/2159-8290.cd-24-1638 · Cited by 22 · see citing works

GAS-STING: a classical DNA recognition pathways to tumor therapy

Wang, X., Lin, M., Zhu, L., & Ye, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1200245 · Cited by 20 · see citing works

The tripartite motif-containing 24 is a multifunctional player in human cancer

Yao, Y., Zhou, S., Yue, Y., Fu, K., & Xiao, S. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01289-3 · Cited by 19 · see citing works

MAP3K1 mutations confer tumor immune heterogeneity in hormone receptor–positive HER2-negative breast cancer

Cai, Y., Liu, C., Zhang, Y., Liu, Y., Chen, L., Xiong, X., Shao, Z., & Yu, K. (2024) · Journal of Clinical Investigation · doi:10.1172/jci183656 · Cited by 18 · see citing works

NFE2L3 drives hepatocellular carcinoma cell proliferation by regulating the proteasome‐dependent degradation of ISGylated p53

Ren, Y., Yang, J., Ding, Z., Zheng, M., Qiu, L., Tang, A., & Huang, D. (2023) · Cancer Science · doi:10.1111/cas.15887 · Cited by 16 · see citing works

cGAS–STING Signaling in Central Nervous System Diseases: Neuroinflammatory Mechanisms and Immune Regulation

Wang, W., Wang, L., Zhong, X., Dong, L., Zhang, L., & Hu, J. X. (2025) · Cell Biochemistry and Function · doi:10.1002/cbf.70146 · Cited by 15 · see citing works

DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage

Justice, J., Reed, T. J., Phelan, B., Greco, T. M., Hutton, J. E., & Cristea, I. M. (2024) · Cell Systems · doi:10.1016/j.cels.2024.03.003 · Cited by 15 · see citing works

STING Promotes the Progression of ADPKD by Regulating Mitochondrial Function, Inflammation, Fibrosis, and Apoptosis

Wu, J., Cheng, S., Lee, G., Agborbesong, E., Li, X., Zhou, X., & Li, X. (2024) · Biomolecules · doi:10.3390/biom14101215 · Cited by 14 · see citing works

The cGAS-STING pathway in cancer: friend or foe

Li, Q., Song, Q., Ma, L., Kang, K., Zhu, X., Li, Y., Lin, X., Lu, X., Zeng, Z., Li, G., et al. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-08607-2 · Cited by 13 · see citing works

Mechanism of Apigenin against breast cancer stem cells: network pharmacology and experimental validation

Ou, M., Deng, Z., Shi, Y., He, J., Ye, Z., Guo, M. H., Cheng, G., Wu, J., & Lv, L. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1496664 · Cited by 13 · see citing works

High mobility group A1 (HMGA1) promotes esophageal squamous cell carcinoma progression by inhibiting STING-mediated anti-tumor immunity

He, K.-Y., Zhao, A., Guo, J.-R., Wu, D., Liu, H., Gao, F., Liu, M., Yang, J.-Y., Lei, X., Li, J.-Q., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60221-6 · Cited by 12 · see citing works

STING-targeting PROTACs: emerging therapeutic tools for enhanced immunotherapy in inflammatory diseases

Jiang, W.-Q., Yang, X.-P., Liu, H., Wang, C., Niu, H., & Yu, W. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1631132 · Cited by 11 · see citing works

TREX1 exonuclease in immunity and disease

Shang, Z., Wang, L., & Zhou, W. (2025) · International Immunology · doi:10.1093/intimm/dxaf037 · Cited by 12 · see citing works

Role of cGAS-STING pathway in fibrotic disease

Feng, L., Zhang, F., Cao, J., & Xiong, W. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107971 · Cited by 12 · see citing works

Mutant p53 leads to low‐grade IFN‐I‐induced inflammation and impairs cGAS–STING signalling in mice

Qin, Z., Liu, H., Sheng, Q., Dan, J., Wu, X., Li, H., Wang, L., Zhang, S., Yuan, C., Yuan, H., et al. (2023) · European Journal of Immunology · doi:10.1002/eji.202250211 · Cited by 11 · see citing works

The role of signaling pathways mediated by the GPCRs CysLTR1/2 in melanocyte proliferation and senescence

Huber, T., Horioka-Duplix, M., Chen, Y., Saca, V. R., Ceraudo, E., Chen, Y., & Sakmar, T. P. (2024) · Science Signaling · doi:10.1126/scisignal.adp3967 · Cited by 11 · see citing works

Review of Excessive Cytosolic DNA and Its Role in AIM2 and cGAS-STING Mediated Psoriasis Development

Xu, T., Zhong, X., Luo, N., Ma, W., & Hao, P. (2024) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s476785 · Cited by 11 · see citing works

Therapeutic modulation of cGAS-STING pathway in neurodegeneration

Sharma, V., Verma, R., Sharma, P., & Singh, T. G. (2025) · Brain Research · doi:10.1016/j.brainres.2025.149784 · Cited by 12 · see citing works

The role of nitric oxide in inflammation, tumor microenvironment, and cancer therapy

Nair, A., Madhyastha, H., Revanasiddappa, B. C., Pai, V., Kumar, D., Neenu, M. K., & Prabhu, P. P. (2026) · Nitric Oxide · doi:10.1016/j.niox.2026.02.005 · Cited by 10 · see citing works

TIME Is Ticking for Cervical Cancer

Kumar, V., Bauer, C., & Stewart, J. H. (2023) · Biology · doi:10.3390/biology12070941 · Cited by 11 · see citing works

Arginine methylation-dependent cGAS stability promotes non-small cell lung cancer cell proliferation

Liu, X., Zheng, W., Zhang, L., Cao, Z., Cong, X., Hu, Q., Hou, J., Jin, X., Yuan, Q., Lin, L., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216707 · Cited by 10 · see citing works

Zn2+ enhanced the anti-breast cancer activity of fucoidan based nanoparticles by activating the cGAS-STING pathway

Xue, P., Wang, Y., Wang, X. J., Zhou, S., Wu, X., Long, L., & Guo, C. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.156729 · Cited by 10 · see citing works

Nucleases: From Primitive Immune Defenders to Modern Biotechnology Tools

Hernández, F. J. (2024) · Immunology · doi:10.1111/imm.13884 · Cited by 10 · see citing works

Ultrasound-induced mechanical damage of cancer cell cytoskeleton causes disruption of nuclear envelope and activation of cGAS-STING

Federico, G., Carotenuto, A. R., Cutolo, A., Palumbo, S., Moccia, M., Paladino, S., Santoro, M., Russo, T., Fraldi, M., & Carlomagno, F. (2025) · Scientific Reports · doi:10.1038/s41598-025-03317-9 · Cited by 10 · see citing works

Promising therapeutic efficacy and safety of a novel integrin α6-targeting peptide-drug conjugate in lung adenocarcinoma

Gao, W., Wang, Q.-L., Li, S., Chen, W., Luo, B., Xie, K., Liao, H., Zhong, L., Chen, Y., Wen, Z., et al. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02395-7 · Cited by 10 · see citing works

Parkin activates innate immunity and promotes antitumor immune responses

Perego, M., Yeon, M., Agarwal, E., Milcarek, A. T., Bertolini, I., Camisaschi, C., Ghosh, J. C., Tang, H., Grandvaux, N., Ruscetti, M. A., et al. (2024) · Journal of Clinical Investigation · doi:10.1172/jci180983 · Cited by 9 · see citing works

The role of cGAS-STING signaling in the development and therapy of head and neck squamous cell carcinoma

Shao, C., Chen, J., Qiang, B., Ye, J., Yan, F., & Zhu, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1451305 · Cited by 9 · see citing works

STING exerts antiviral innate immune response by activating pentose phosphate pathway

Wu, D., Zhao, Z., Yin, W.-T., Liu, H., Xiang, X.-Y., Zhu, L., Li, J., Yan, Z.-H., Li, Y., Jian, Y., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01983-2 · Cited by 9 · see citing works

Mutant p53 variants differentially impact replication initiation and activate cGAS-STING to affect immune checkpoint inhibition

Liu, K., Garan, L. A. W., Lin, F., & Lin, W.-C. (2025) · Communications Biology · doi:10.1038/s42003-025-09050-3 · Cited by 9 · see citing works

The cGAS/STING/IFN-1 Response in Squamous Head and Neck Cancer Cells after Genotoxic Challenges and Abrogation of the ATR-Chk1 and Fanconi Anemia Axis

Zahnreich, S., Guerzyfy, S. E., Kaufmann, J., & Schmidberger, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914900 · Cited by 10 · see citing works

Regulation of mitochondrial apoptosis via siRNA-loaded metallo-alginate hydrogels: A localized and synergistic antitumor therapy

Alarcón, J. F., Artigues, M., Rodriguez-Camenforte, N., Sitia, G., Guerra‐Rebollo, M., Borrós, S., & Fornaguera, C. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123164 · Cited by 8 · see citing works

Advances in nanoplatform-based multimodal combination therapy activating STING pathway for enhanced anti-tumor immunotherapy

Zhang, H., Xu, X., Li, S., Huang, H., Zhang, K., Li, W., Wang, X., Yang, J., Yin, X., Qu, C., et al. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114573 · Cited by 9 · see citing works

Primary cilia prevent activation of the cGAS-STING pathway during mouse decidualization

Li, B., He, Y., Yao, W.-X., Jin, D.-D., Luo, H., Li, M., Wu, Y., & Yang, Z. (2025) · Communications Biology · doi:10.1038/s42003-025-08030-x · Cited by 8 · see citing works

Liquid‒liquid phase separation: a potentially fundamental mechanism of sepsis

Chen, H., Huang, S., Quan, L., Yu, C., Zhu, Y., Sun, X., Zhang, Y., Deng, L., & Chen, F. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02599-2 · Cited by 8 · see citing works

Recombinant immunotoxin induces tumor intrinsic STING signaling against head and neck squamous cell carcinoma

Xie, G., Shan, L., Yang, C., Liu, Y., Pang, X., Teng, S., Wu, T.-C., & Gu, X. (2023) · Scientific Reports · doi:10.1038/s41598-023-45797-7 · Cited by 8 · see citing works

Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing

Demeule, M., Currie, J.-C., Charfi, C., Zgheib, A., Cousineau, I., Lullier, V., Béliveau, R., Marsolais, C., & Annabi, B. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1355945 · Cited by 8 · see citing works

The molecular crosstalk between innate immunity and DNA damage repair/response: Interactions and effects in cancers

Omidvar, S., Vahedian, V., Sourani, Z., Yari, D., Asadi, M., Jafari, N., Khodavirdilou, L., Bagherieh, M., Shirzad, M., & Hosseini, V. (2024) · Pathology - Research and Practice · doi:10.1016/j.prp.2024.155405 · Cited by 8 · see citing works

Selenium nanoparticle-delivered MDM2 inhibitor reactivates p53 and reprograms tumor immune microenvironment in colorectal cancer

You, W., Feng, J., Guo, L., Yan, J., & Yan, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1684611 · Cited by 7 · see citing works

Protein ubiquitination in ovarian cancer immunotherapy: The progress and therapeutic strategy

Guo, H., Wei, J., Zhang, Y., Wang, L., Wan, J., Wang, W., Gao, L., Li, J., Sun, T., & Ma, L. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.101158 · Cited by 7 · see citing works

Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma

Martino, M. D., Daviaud, C., Lira, M. C., Hernandez-Zirofsky, K., & Vanpouille‐Box, C. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217856 · Cited by 6 · see citing works

Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

Xu, B., Hou, X., Wang, M. X., Qiu, L., Chen, X., Deng, G., Zhou, D., Feng, Y., Han, J., Meng, X., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116623 · Cited by 6 · see citing works

The entanglement of DNA damage and pattern recognition receptor signaling

Ha, C. T., Tageldein, M. M., & Harding, S. M. (2023) · DNA repair · doi:10.1016/j.dnarep.2023.103595 · Cited by 6 · see citing works

Harnessing p53 to Improve Immunotherapy for Lung Cancer Treatment

Niu, X., & Martinez, L. A. (2023) · Cancer Research · doi:10.1158/0008-5472.can-23-3929 · Cited by 6 · see citing works

The Role and Mechanism of Innate Immune Regulation in Overcoming Oxaliplatin Resistance and Enhancing Anti-Tumor Efficacy in Colorectal Cancer

Wang, X., Xi, M., Lu, X., & Tan, X. (2025) · Pharmaceuticals · doi:10.3390/ph18030317 · Cited by 5 · see citing works

Deciphering cGAS-STING signaling: implications for tumor immunity and hepatocellular carcinoma

Chandramoorthy, H. C. K., Saleh, R. O., Altalbawy, F. M. A., Mohammed, J. S., Ganesan, S., Kundlas, M., Premkumar, J., Ray, S., Mustafa, Y. F., & Abbas, J. K. K. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04240-6 · Cited by 5 · see citing works

APOBEC3G Is a p53-Dependent Restriction Factor in Respiratory Syncytial Virus Infection of Human Cells Included in the p53/Immune Axis

Gladwell, W., Yost, O. L., Li, H., Bell, W. J., Chen, S., Ward, J. M., Kleeberger, S. R., Resnick, M. A., & Menéndez, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242316793 · Cited by 5 · see citing works

Mechanisms of Immune Sensing of DNA Damage

Goddard, A. M., Cho, M.-G., Lerner, L. M., & Gupta, G. P. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2023.168424 · Cited by 5 · see citing works

T‐Rex escaped from the cytosolic park: Re‐thinking the impact of TREX1 exonuclease deficiencies on genomic stability

Técher, H. (2024) · BioEssays · doi:10.1002/bies.202400066 · Cited by 5 · see citing works

p53 regulates the mitochondrial immune checkpoint

Vanpouille‐Box, C., & Galluzzi, L. (2023) · Trends in Immunology · doi:10.1016/j.it.2023.03.001 · Cited by 5 · see citing works

Oroxin A suppresses colorectal tumor growth by regulating the TRIM24-mediated ferroptosis and TSPO pathway

He, C., Weng, C., Lai, Z., Luo, H., Chen, K., Li, T., Li, W., & Li, G. (2025) · iScience · doi:10.1016/j.isci.2025.113196 · Cited by 4 · see citing works

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Shi, X., Shen, Y., Lv, M., Sun, Y., Lin, Y., Wang, Z., Jie, X., Liu, Z., Liu, Y., Fu, Y., et al. (2025) · Advanced Science · doi:10.1002/advs.202508481 · Cited by 4 · see citing works

From Genome Guardian to Immune Modulator: The Expanding Roles of Tumor Suppressor p53

Wang, W., Liu, J., Feng, Z., & Hu, W. (2025) · Molecular and Cellular Biology · doi:10.1080/10985549.2025.2571187 · Cited by 4 · see citing works

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Zhu, J., Fu, S., Zou, X., Zeng, H., Cui, G., Peng, Y., Tang, D., Zhang, F., Shen, H., Zeng, S., et al. (2025) · Advanced Science · doi:10.1002/advs.202500271 · Cited by 4 · see citing works

How enzyme‐centered approaches are advancing research on cyclic oligo‐nucleotides

Wenzl, S. J., & Mann, C. C. D. O. (2024) · FEBS Letters · doi:10.1002/1873-3468.14838 · Cited by 4 · see citing works

Activation of T Cell–Intrinsic p53 by Acetylation Elicits Antitumor Immunity to Boost Cancer Immunotherapy

Yan, X., Xu, W., Yao, H., Wu, Z., Ning, J., Zhao, S., Liu, Y., Zhang, M., Xu, D., Shen, Z., et al. (2025) · Cancer Discovery · doi:10.1158/2159-8290.cd-25-0649 · Cited by 3 · see citing works

CDKN1A and cellular senescence are associated with immune resistance in advanced lung adenocarcinoma

Wang, S., Duan, F., Fu, S., Cui, P. L., Shi, Y., Zhang, L., Mi, X., Xu, Y., Wang, G., Cai, S., et al. (2025) · Clinical and Experimental Medicine · doi:10.1007/s10238-025-01926-2 · Cited by 3 · see citing works

Association of YY1 with STING activation and the inflammatory response during early muscle injury repair

Yan, X., Hou, Z., Li, W., Miao, S., Zhang, Z., Luo, J., Tao, Y., Li, Q., Zhao, J., & Xu, Z. (2025) · Molecular Immunology · doi:10.1016/j.molimm.2025.11.011 · Cited by 3 · see citing works

Stenotrophomonas promotes gastrointestinal tumor progression via STING degradation in tumour cells and mitigated immune response

Feng, H., Chen, K., Xi, Z., Xia, B., Chen, X., Huang, Y., Huang, Z., Guo, J., Zhu, D., Ling, F., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-68649-0 · Cited by 3 · see citing works

Carrier-Free Nano-Proteolysis Targeting Chimeras Enable Selective Protein Degradation and Enhance Photoimmunometabolic Therapy against Lung Adenocarcinoma

Wang, X., Liu, L., Tian, J., Kong, Z., Lv, F., Yan, J., Li, S., Ma, Z., Guo, D., Wang, Y., et al. (2026) · ACS Nano · doi:10.1021/acsnano.5c21154 · Cited by 3 · see citing works

Mutant p53 Suppresses Innate Immune Signaling to Promote Tumorigenesis

Ghosh, M., Saha, S., Bettke, J. A., Nagar, R., Parrales, A., Iwakuma, T., van der Velden, A. W. M., & Martinez, L. A. (2020) · Cancer Cell · doi:10.1016/j.ccell.2021.01.003 · Cited by 344 · see citing works

Abstract 2079: Tumor cell intrinsic inactivation of TREX1 increases type I IFN signaling and immune cell recruitment

Mathsyaraja, H., Wolf, B., Cortez, C., Kashishian, A., Karst, A. M., Cueva, M., Wang, M., Keegan, K. S., & Cain, J. (2022) · Cancer Research · doi:10.1158/1538-7445.am2022-2079

A novel TREX1 inhibitor, VB-85680, upregulates cellular interferon responses

Flowers, S. J., Petronella, B. A., McQueney, M. S., Fanelli, B., Eisenberg, W., Uveges, A. J., Roden, A. L., Salowe, S. P., Bommireddy, V., Letourneau, J. J., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305962 · Cited by 14 · see citing works

Abstract LB361: The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated anti-tumor immunity

Lim, J. K., Rodriguez, R., Williams, K., Silva, J., Gutierrez, A., Tyler, P. M., Baharom, F., Sun, T., Lin, E., Martin, S. E., et al. (2024) · Cancer Research · doi:10.1158/1538-7445.am2024-lb361

The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity

Lim, J. K., Rodriguez, R., Williams, K., Silva, J., Gutierrez, A. G., Tyler, P. M., Baharom, F., Sun, T., Lin, E., Martin, S. E., et al. (2024) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-23-1078 · Cited by 54 · see citing works