Viral myocarditis involves the generation of autoreactive T cells with multiple antigen specificities that localize in lymphoid and non-lymphoid organs in the mouse model of CVB3 infection

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

REED, L. J., & Muench, H. (1938) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a118408 · Cited by 20,341 · see citing works

Individual Comparisons by Ranking Methods

Wilcoxon, F. (1945) · Biometrics Bulletin · doi:10.2307/3001968 · Cited by 15,354 · see citing works

On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other

Mann, H. B., & Whitney, D. R. (1947) · The Annals of Mathematical Statistics · doi:10.1214/aoms/1177730491 · Cited by 14,320 · see citing works

A simple method of estimating 50 per cent end points

Muench, H. (1938) · Medical Entomology and Zoology · Cited by 8,377 · see citing works

The EMBL-EBI search and sequence analysis tools APIs in 2019

Madeira, F., Park, Y. M., Lee, J., Buso, N., Gur, T., Madhusoodanan, N., Basutkar, P., Tivey, A. R. N., Potter, S. C., Finn, R. D., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz268 · Cited by 4,167 · see citing works

Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases

Caforio, A. L. P., Pankuweit, S., Arbustini, E., Basso, C., Gimeno-Blanes, J., Felix, S. B., Fu, M., Heliö, T., Heymans, S., Jahns, R., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht210 · Cited by 3,479 · see citing works

Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside

Pebay‐Peyroula, E., Dahout-Gonzalez, C., Kahn, R., Trézéguet, V., Lauquin, G. J. ‐., & Brandolin, G. (2003) · Nature · doi:10.1038/nature02056 · Cited by 998 · see citing works

High Prevalence of Viral Genomes and Multiple Viral Infections in the Myocardium of Adults With “Idiopathic” Left Ventricular Dysfunction

Kühl, U., Pauschinger, M., Noutsias, M., Seeberg, B., Bock, C. –., Laßner, D., Poller, W. C., Kandolf, R., & Schultheiß, H. (2005) · Circulation · doi:10.1161/01.cir.0000155616.07901.35 · Cited by 710 · see citing works

Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease

Fujinami, R. S., von Herrath, M. G., Christen, U., & Whitton, J. L. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.1.80-94.2006 · Cited by 685 · see citing works

Viral myocarditis—diagnosis, treatment options, and current controversies

Pollack, A., Kontorovich, A. R., Fuster, V., & Dec, G. W. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.108 · Cited by 657 · see citing works

Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus

Kaufman, D. L., Erlander, M. G., Clare-Salzler, M., Atkinson, M. A., Maclaren, N. K., & Tobin, A. J. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115573 · Cited by 490 · see citing works

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

Wooldridge, L., Makinde, J., van den Berg, H. A., Skowera, A., Miles, J. J., Tan, M. P., Dolton, G. M., Clement, M., Llewellyn‐Lacey, S., Price, D. A., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.289488 · Cited by 459 · see citing works

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes.

Atkinson, M. A., Bowman, M. A., Campbell, L., Darrow, B. L., Kaufman, D. L., & Maclaren, N. K. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117567 · Cited by 448 · see citing works

Myocarditis

Fung, G., Luo, H., Qiu, Y., Yang, D., & McManus, B. (2016) · Circulation Research · doi:10.1161/circresaha.115.306573 · Cited by 444 · see citing works

Experimental Autoimmune Encephalomyelitis in the Mouse

Miller, S. D., & Karpus, W. J. (2007) · Current Protocols in Immunology · doi:10.1002/0471142735.im1501s77 · Cited by 404 · see citing works

Molecular Biology and Pathogenesis of Viral Myocarditis

Esfandiarei, M., & McManus, B. M. (2008) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.151534 · Cited by 387 · see citing works

Myocarditis

Blauwet, L. A., & Cooper, L. T. (2010) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2009.11.006 · Cited by 374 · see citing works

T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses

Saeidi, A., Zandi, K., Cheok, Y. Y., Saeidi, H., Wong, W. F., Lee, C. Y. Q., Cheong, H. C., Yong, Y. K., Larsson, M., & Shankar, E. M. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02569 · Cited by 346 · see citing works

The liver as a site of T-cell apoptosis: graveyard, or killing field?

Crispe, I. N., Dao, T., Klugewitz, K., Mehal, W. Z., & Metz, D. P. (2000) · Immunological Reviews · doi:10.1034/j.1600-0528.2002.017412.x · Cited by 321 · see citing works

Antigenic Structure of Polioviruses of Serotypes 1, 2 and 3

Minor, P. D., Ferguson, M. A. J., Evans, D. M. A., Almond, J. W., & Icenogle, J. P. (1986) · Journal of General Virology · doi:10.1099/0022-1317-67-7-1283 · Cited by 306 · see citing works

Circulating Cardiac Autoantibodies in Dilated Cardiomyopathy and Myocarditis: Pathogenetic and Clinical Significance

Caforio, A. L. P., Mahon, N., Tona, F., & McKenna, W. J. (2002) · European Journal of Heart Failure · doi:10.1016/s1388-9842(02)00010-7 · Cited by 274 · see citing works

Molecular Biology and Pathogenesis of Viral Myocarditis

Esfandiarei, M., & McManus, B. M. (2007) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathol.3.121806.151534 · Cited by 259 · see citing works

Epitopes of streptococcal M proteins shared with cardiac myosin.

Dale, J. B., & Beachey, E. H. (1985) · The Journal of Experimental Medicine · doi:10.1084/jem.162.2.583 · Cited by 227 · see citing works

Coxsackievirus B3 Replication and Pathogenesis

Garmaroudi, F. S., Marchant, D., Hendry, R. G., Luo, H., Yang, D., Ye, X., Shi, J., & McManus, B. M. (2015) · Future Microbiology · doi:10.2217/fmb.15.5 · Cited by 225 · see citing works

Chapter 4 Pathogenesis of Myocarditis and Dilated Cardiomyopathy

Cihakova, D., & Rose, N. R. (2008) · Advances in Immunology · doi:10.1016/s0065-2776(08)00604-4 · Cited by 223 · see citing works

Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development

Arai, M., Otsu, K., MacLennan, D. H., & Periasamy, M. (1992) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1992.262.3.c614 · Cited by 218 · see citing works

Autoantibodies in Heart Failure and Cardiac Dysfunction

Kaya, Z., Leib, C., & Katus, H. A. (2012) · Circulation Research · doi:10.1161/circresaha.111.243360 · Cited by 189 · see citing works

Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses, and human cardiac myosin.

Cunningham, M. W., Antone, S. M., Gulizia, J. M., McManus, B. M., Fischetti, V. A., & Gauntt, C. J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.4.1320 · Cited by 176 · see citing works

Update on coxsackievirus B3 myocarditis

Fairweather, D., Stafford, K. A., & Sung, Y. K. (2012) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e328353372d · Cited by 165 · see citing works

Mimicry and Antibody-Mediated Cell Signaling in Autoimmune Myocarditis

Li, Y., Heuser, J. S., Cunningham, L. C., Kosanke, S. D., & Cunningham, M. W. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.11.8234 · Cited by 155 · see citing works

Viral myocarditis

Rose, N. R. (2016) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000303 · Cited by 141 · see citing works

Myocarditis-inducing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting cells in the heart.

Donermeyer, D. L., Beisel, K. W., Allen, P. M., & Smith, S. C. (1995) · The Journal of experimental medicine · doi:10.1084/jem.182.5.1291 · Cited by 140 · see citing works

Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.

Schaeffer, E. B., Sette, A., Johnson, D. L., Bekoff, M. C., Smith, J. A., Grey, H. M., & Buus, S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.12.4649 · Cited by 111 · see citing works

Identification of T cell autoepitopes that cross-react with the C-terminal segment of the M protein of group A streptococci

Pruksakorn, S., Currie, B. J., Brandt, E. R., Phornphutkul, C., Hunsakunachal, S., Manmontri, A., Robinson, J. H., Kehoe, M., Galbraith, A. J., & Good, M. F. (1994) · International Immunology · doi:10.1093/intimm/6.8.1235 · Cited by 105 · see citing works

Expression of Cardiac Calcium Regulatory Proteins in Atrium v Ventricle in Different Species

Lüss, I., Boknı́k, P., Jones, L. R., Kirchhefer, U., Knapp, J., Linck, B., Lüss, H., Meissner, A., Müller, F. U., Schmitz, W. L., et al. (1999) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1999.0962 · Cited by 97 · see citing works

Induction of multiple heart autoantibodies in mice with coxsackievirus B3- and cardiac myosin-induced autoimmune myocarditis.

Neumann, D. A., Rose, N. R., Ansari, A. A., & Herskowitz, A. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.152.1.343 · Cited by 96 · see citing works

Postinfectious Autoimmunity: Two Distinct Phases of Coxsackievirus B3‐Induced Myocarditisa

Rose, N. R., Wolfgram, L. J., Herskowitz, A., & Beisel, K. W. (1986) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1986.tb20864.x · Cited by 95 · see citing works

Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes

Levy, S., Chen, Y., Graham, B. H., & Wallace, D. C. (2000) · Gene · doi:10.1016/s0378-1119(00)00252-3 · Cited by 93 · see citing works

Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies

Mascaro-Blanco, A., Alvarez, K., Yu, X., Lindenfeld, J., Olansky, L., Lyons, T., Duvall, D., Heuser, J. S., Gosmanova, A., Rubenstein, C. J., et al. (2008) · Autoimmunity · doi:10.1080/08916930802031579 · Cited by 86 · see citing works

Cardiac Autoantibodies to Myosin and Other Heart-specific Autoantigens in Myocarditis and Dilated Cardiomyopathy

Caforio, A. L. P., Mahon, N., & McKenna, W. J. (2001) · Autoimmunity · doi:10.3109/08916930109007385 · Cited by 79 · see citing works

Molecular Basis for Recognition of an Arthritic Peptide and a Foreign Epitope on Distinct MHC Molecules by a Single TCR

Basu, D., Horvath, S. C., Matsumoto, I., Fremont, D. H., & Allen, P. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.11.5788 · Cited by 78 · see citing works

Unresolved issues in theories of autoimmune disease using myocarditis as a framework

Root-Bernstein, R. S., & Fairweather, D. (2014) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2014.11.022 · Cited by 77 · see citing works

Cytolytic cross-reactive antibodies directed against the cardiac membrane and viral proteins in coxsackievirus B3 and B4 myocarditis. Characterization and pathogenetic relevance.

Maisch, B., Bauer, E., Cirsi, M., & KOCHSIEK, K. (1993) · PubMed · Cited by 76 · see citing works

A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1233-244.

Yauch, R. L., & Kim, B. S. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.10.4508 · Cited by 70 · see citing works

A Viral Peptide with Limited Homology to a Self Peptide Can Induce Clinical Signs of Experimental Autoimmune Encephalomyelitis

Gautam, A. M., Liblau, R., Chelvanayagam, G., Steinman, L., & Boston, T. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.1.60 · Cited by 70 · see citing works

Detection of Autoreactive Myelin Proteolipid Protein 139–151-Specific T Cells by Using MHC II (IAs) Tetramers

Reddy, J., Bettelli, E., Nicholson, L. B., Waldner, H., Jang, M.-H., Wucherpfennig, K. W., & Kuchroo, V. K. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.2.870 · Cited by 69 · see citing works

Coxsackievirus B3 infection leads to the generation of cardiac myosin heavy chain-α-reactive CD4 T cells in A/J mice

Gangaplara, A., Massilamany, C., Brown, D. M., Delhon, G., Pattnaik, A. K., Chapman, N., Rose, N., Steffen, D., & Reddy, J. (2012) · Clinical Immunology · doi:10.1016/j.clim.2012.07.003 · Cited by 69 · see citing works

Identification of novel mimicry epitopes for cardiac myosin heavy chain-α that induce autoimmune myocarditis in A/J mice

Massilamany, C., Gangaplara, A., Steffen, D. J., & Reddy, J. (2011) · Cellular Immunology · doi:10.1016/j.cellimm.2011.08.013 · Cited by 69 · see citing works

Biology and significance of T‐cell apoptosis in the liver

Park, S., Murray, D. A., John, B., & Crispe, I. (2002) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.2002.01065.x · Cited by 56 · see citing works

Recombinant cardiac myosin fragment induces experimental autoimmune myocarditis via activation of Th1 and Th17 immunity

Daniels, M. D., Hyland, K. V., Wang, K., & Engman, D. M. (2008) · Autoimmunity · doi:10.1080/08916930802167902 · Cited by 49 · see citing works

Pertussis Toxin Is Superior to TLR Ligands in Enhancing Pathogenic Autoimmunity, Targeted at a Neo-Self Antigen, by Triggering Robust Expansion of Th1 Cells and Their Cytokine Production

Fujimoto, C., Yu, C., Shi, G., Vistica, B. P., Wawrousek, E. F., Klinman, D. M., Chan, C., Egwuagu, C. E., & Gery, I. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.10.6896 · Cited by 47 · see citing works

Intricacies of cardiac damage in coxsackievirus B3 infection: Implications for therapy

Massilamany, C., Gangaplara, A., & Reddy, J. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.09.136 · Cited by 47 · see citing works

T cell recognition of bovine ribonuclease. Self/non-self discrimination at the level of binding to the I-Ak molecule.

Lorenz, R. G., Tyler, A. N., & Allen, P. M. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.141.12.4124 · Cited by 45 · see citing works

Detection of autoreactive CD4 T cells using major histocompatibility complex class II dextramers

Massilamany, C., Upadhyaya, B., Gangaplara, A., KUSZYNSKI, C. A., & Reddy, J. (2011) · BMC Immunology · doi:10.1186/1471-2172-12-40 · Cited by 45 · see citing works

T lymphocyte responses in CVB3-induced murine myocarditis.

Huber, S. A., Polgár, J., Moraska, A. F., Cunningham, M. W., Schwimmbeck, P. L., & Schultheiss, P. (1993) · PubMed · Cited by 43 · see citing works

Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice

Yao, Q., Cao, G., Li, M., Wu, B., Zhang, X., Zhang, T., Guo, J., Yin, H., Shi, L., Chen, J., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1809744115 · Cited by 41 · see citing works

An epitope from Acanthamoeba castellanii that cross-react with proteolipid protein 139-151-reactive T cells induces autoimmune encephalomyelitis in SJL mice

Massilamany, C., Steffen, D. J., & Reddy, J. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.11.006 · Cited by 37 · see citing works

Persistence of virus and viral genome in myocardium after Coxsackievirus B3-induced murine myocarditis

Rabausch-Starz, I., Schwaiger, A., Grünewald, K. J. T., Müller‐Hermelink, H. K., & Neu, N. (1994) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.1994.tb06232.x · Cited by 37 · see citing works

The role of the ADP/ATP carrier in the pathogenesis of viral heart disease

Schulze, K. J., & Schultheiß, H. (1995) · European Heart Journal · doi:10.1093/eurheartj/16.suppl_o.64 · Cited by 35 · see citing works

Autoimmune myocarditis and dilated cardiomyopathy: focus on cardiac autoantibodies

Caforio, A. L. P., Daliento, L., Angelini, A., Bottaro, S., Vinci, A., Dequal, G., Tona, F., Iliceto, S., Thiene, G., & McKenna, W. J. (2005) · Lupus · doi:10.1191/0961203305lu2193oa · Cited by 34 · see citing works

Pertussis toxin alters the innate and the adaptive immune responses in a pertussis-dependent model of autoimmunity

Agarwal, R. K., Sun, S. H., Su, S. B., Chan, C., & Caspi, R. R. (2002) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(02)00203-5 · Cited by 34 · see citing works

Triggers of Inflammatory Heart Disease

Lasrado, N., Yalaka, B., & Reddy, J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00192 · Cited by 31 · see citing works

Eradication of viral myocarditis

BABOONIAN, C., & McKenna, W. J. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00655-7 · Cited by 29 · see citing works

Mapping of Antigenic Determinants of the Adenine-Nucleotide Translocator and Coxsackie B3 Virus with Synthetic Peptides: Use for the Diagnosis of Viral Heart Disease

Schwimmbeck, P. L., Schwimmbeck, N. K., Schultheiß, H., & Strauer, B. E. (1993) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1993.1109 · Cited by 29 · see citing works

Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334–352 that induces autoimmune myocarditis in A/J mice

Massilamany, C., Gangaplara, A., Basavalingappa, R. H., Arumugam, R., Khalilzad-Sharghi, V., Han, Z., Othman, S. F., Steffen, D. J., & Reddy, J. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.09.016 · Cited by 28 · see citing works

Detection of cardiac myosin heavy chain-α-specific CD4 cells by using MHC class II/IAk tetramers in A/J mice

Massilamany, C., Gangaplara, A., Chapman, N. M., Rose, N., & Reddy, J. (2011) · Journal of Immunological Methods · doi:10.1016/j.jim.2011.07.004 · Cited by 26 · see citing works

Heart-specific autoantibodies can be eluted from the hearts of Coxsackievirus B3-infected mice

NEUMANN, D. A., Lane, J. R., Lafond-Walker, A., Allen, G. S., Wulff, S. M., Herskowitz, A., & Rose, N. R. (1991) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.1991.tb02945.x · Cited by 24 · see citing works

Hepatic damage caused by coxsackievirus B3 is dependent on age-related tissue tropisms associated with the coxsackievirus-adenovirus receptor

Liu, J.-Y., Wang, S., Chen, I., Yu, C., & Liu, H. (2013) · Pathogens and Disease · doi:10.1111/2049-632x.12044 · Cited by 22 · see citing works

Gender differences in CNS autoimmunity induced by mimicry epitope for PLP 139–151 in SJL mice

Massilamany, C., Thulasingam, S., Steffen, D. J., & Reddy, J. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.09.011 · Cited by 22 · see citing works

Tissue-specific Translation of Murine Branched-chain α-Ketoacid Dehydrogenase Kinase mRNA Is Dependent upon an Upstream Open Reading Frame in the 5′-Untranslated Region

Muller, E. A., & Danner, D. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406550200 · Cited by 18 · see citing works

LMKB/MARF1 Localizes to mRNA Processing Bodies, Interacts with Ge-1, and Regulates IFI44L Gene Expression

Bloch, D. B., Li, P., Bloch, E. G., Berenson, D. F., Galdos, R. L., Arora, P. K., Malhotra, R. K., Wu, C., & Yang, W.-H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094784 · Cited by 18 · see citing works

Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice

Basavalingappa, R. H., Massilamany, C., Krishnan, B., Gangaplara, A., Kang, G., Khalilzad-Sharghi, V., Han, Z., Othman, S., Li, Q., Riethoven, J.-J., et al. (2016) · The American Journal of Pathology · doi:10.1016/j.ajpath.2016.08.005 · Cited by 17 · see citing works

Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice

Krishnan, B., Massilamany, C., Basavalingappa, R. H., Gangaplara, A., Rajasekaran, R. A., Afzal, M. Z., Khalilzad-Sharghi, V., Zhou, Y., Riethoven, J.-J., Nandi, S. S., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701090 · Cited by 17 · see citing works

Branched chain α‐ketoacid dehydrogenase kinase 111–130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice

Krishnan, B., Massilamany, C., Basavalingappa, R. H., Gangaplara, A., Kang, G., Li, Q., Uzal, F. A., Strande, J. L., Delhon, G. A., Riethoven, J.-J. M., et al. (2017) · Immunity Inflammation and Disease · doi:10.1002/iid3.177 · Cited by 15 · see citing works

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers

Massilamany, C., Gangaplara, A., Jia, T., Elowsky, C. G., Li, Q., Zhou, Y., & Reddy, J. (2014) · Journal of Visualized Experiments · doi:10.3791/51679 · Cited by 11 · see citing works

β1-Adrenergic Receptor Contains Multiple IAk and IEk Binding Epitopes That Induce T Cell Responses with Varying Degrees of Autoimmune Myocarditis in A/J Mice

Basavalingappa, R. H., Massilamany, C., Krishnan, B., Gangaplara, A., Rajasekaran, R. A., Afzal, M. Z., Riethoven, J.-J., Strande, J. L., Steffen, D., & Reddy, J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01567 · Cited by 11 · see citing works

Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes

Dunster, K., Lai, F. P. L., & Sentry, J. W. (2005) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2005.02774.x · Cited by 10 · see citing works

Monomethoxypolyethylene Glycol-Modified Cardiac Myosin Treatment Blocks the Active and Passive Induction of Experimental Autoimmune Myocarditis

Hamada, Y., Takata, M., Kiyoku, H., Enzan, H., Doi, Y., & Fujimoto, S. (2004) · Circulation Journal · doi:10.1253/circj.68.149 · Cited by 8 · see citing works

Heart Transplantation in Endstage Rheumatic Heart Disease

Chi, N., Chou, N., Yu, Y., Yu, H., Wu, I., Chen, Y., Huang, S., Ko, W., & Wang, S. (2014) · Circulation Journal · doi:10.1253/circj.cj-13-1606 · Cited by 8 · see citing works

コルチゾール慢性投与はブタ冠動脈の過剰収縮を誘発する Rhoキナーゼ関与の可能性(Chronic Administration of Cortisol Induces Hyperconstriction of Porcine Coronary Arteries: Possible Involvement of Rho-Kinas)

Hizume, T., Uwatoku, T., Oi, K., Abe, K., & Shimokawa, H. (2004) · Circulation · Cited by 6 · see citing works

COVID-19 and autoimmune diseases

Liu, Y., Sawalha, A. H., & Lu, Q. (2020) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000776 · Cited by 476 · see citing works

Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis

Won, T., Kalinoski, H. M., Wood, M. K., Hughes, D. M., Jaime, C. M., Delgado, P., Talor, M. V., Lasrado, N., Reddy, J., & Čiháková, D. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111611 · Cited by 137 · see citing works

Immunometabolic mechanisms of heart failure with preserved ejection fraction

Schiattarella, G. G., Alcaide, P., Condorelli, G., Gillette, T. G., Heymans, S. R. B., Jones, E. A. V., Kallikourdis, M., Lichtman, A. H., Marelli‐Berg, F. M., Shah, S. J., et al. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00032-w · Cited by 131 · see citing works

Potential clinical implications of molecular mimicry‐induced autoimmunity

Suliman, B. A. (2024) · Immunity Inflammation and Disease · doi:10.1002/iid3.1178 · Cited by 61 · see citing works

Tenascin-C in Heart Diseases—The Role of Inflammation

Imanaka‐Yoshida, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115828 · Cited by 52 · see citing works

Autoimmune Myocarditis, Old Dogs and New Tricks.

Won, T., Song, E. J., Kalinoski, H. M., Moslehi, J. J., & Čiháková, D. (2024) · Circulation Research · doi:10.1161/circresaha.124.323816 · Cited by 51 · see citing works

Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing

(2022) · doi:10.1016/j.isci.2022.103865 · Cited by 43 · see citing works

Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis

Lasrado, N., Gangaplara, A., Massilamany, C., Arumugam, R., Shelbourn, A., Rasquinha, M. T., Basavalingappa, R. H., Delhon, G. A., Xiang, S.-H., Pattnaik, A. K., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-90434-w · Cited by 24 · see citing works

Role of Coxsackievirus B3-Induced Immune Responses in the Transition from Myocarditis to Dilated Cardiomyopathy and Heart Failure

Yip, F., Lai, B., & Yang, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097717 · Cited by 20 · see citing works

The knowns and unknowns of cardiac autoimmunity in viral myocarditis

Mone, K., & Reddy, J. (2023) · Reviews in Medical Virology · doi:10.1002/rmv.2478 · Cited by 19 · see citing works

Vaccines against Group B Coxsackieviruses and Their Importance

Mone, K., Lasrado, N., Sur, M., & Reddy, J. (2023) · Vaccines · doi:10.3390/vaccines11020274 · Cited by 19 · see citing works

Autoimmune-Like Mechanism in Heart Failure Enables Preventive Vaccine Therapy

Martini, E., Cremonesi, M., Felicetta, A., Serio, S., Puccio, S., Pelamatti, E., van Beek, J. J. P., Papadopoulou, V., Catalano, C., Fanuele, F., et al. (2024) · Circulation Research · doi:10.1161/circresaha.124.324999 · Cited by 18 · see citing works

PhIP-Seq Reveals Autoantibodies for Ubiquitously Expressed Antigens in Viral Myocarditis

Rasquinha, M. T., Lasrado, N., Petro-Turnquist, E. M., Weaver, E. A., Venkataraman, T., Anderson, D. R., Laserson, U., Larman, H. B., & Reddy, J. (2022) · Biology · doi:10.3390/biology11071055 · Cited by 17 · see citing works

Cardiac ectopic lymphoid follicle formation in viral myocarditis involving the regulation of podoplanin in Th17 cell differentiation

Zhu, M., Yang, H., Yang, L., Yang, H., Tang, Y., Li, L., Zhu, Y., & Yuan, J. (2021) · The FASEB Journal · doi:10.1096/fj.202101050rr · Cited by 15 · see citing works

Cardiac Myosin-Specific Autoimmune T Cells Contribute to Immune Checkpoint Inhibitor-Associated MyocarditisPreprint

Won, T., Kalinoski, H. M., Wood, M. K., Hughes, D. M., Jaime, C. M., Talor, M. V., Lasrado, N., Reddy, J., & Čiháková, D. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4065075 · Cited by 12 · see citing works

Mt10-CVB3 Vaccine Virus Protects against CVB4 Infection by Inducing Cross-Reactive, Antigen-Specific Immune Responses

Lasrado, N., Arumugam, R., Rasquinha, M. T., Sur, M., Steffen, D. J., & Reddy, J. (2021) · Microorganisms · doi:10.3390/microorganisms9112323 · Cited by 10 · see citing works

A Monovalent Mt10-CVB3 Vaccine Prevents CVB4-Accelerated Type 1 Diabetes in NOD Mice

Rasquinha, M. T., Lasrado, N., Sur, M., Mone, K., Qiu, H., Riethoven, J.-J. M., Sobel, R. A., & Reddy, J. (2022) · Vaccines · doi:10.3390/vaccines11010076 · Cited by 9 · see citing works

Transgenic Mice Expressing Functional TCRs Specific to Cardiac Myhc-α 334–352 on Both CD4 and CD8 T Cells Are Resistant to the Development of Myocarditis on C57BL/6 Genetic Background

Sur, M., Rasquinha, M. T., Arumugam, R., Massilamany, C., Gangaplara, A., Mone, K., Lasrado, N., Yalaka, B., Doiphode, A., Gurumurthy, C. B., et al. (2023) · Cells · doi:10.3390/cells12192346 · Cited by 6 · see citing works

CD4+TEM cells drive the progression from acute myocarditis to dilated cardiomyopathy in CVB3-induced BALB/c mice

Huang, Y., Huang, X., Wei, Z., Dong, J., Lu, J., Tang, Q., Lu, F., Cen, Z., & Wu, W. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111304 · Cited by 5 · see citing works

Comparison and Analysis on the Existing Single-Herbal Strategies against Viral Myocarditis

Cao, Y., Liu, Y., Zhang, T., Pan, J., Lei, W., & Zhang, B. (2021) · Genetics Research · doi:10.1155/2021/9952620 · Cited by 5 · see citing works

Coxsackievirus B3 HFMD animal models in Syrian hamster and rhesus monkey

Duan, S., Zhang, W., Li, Y., Li, Y., Zhao, Y., Jin, W., Liu, Q., Li, M., Sun, W., Chen, L., et al. (2024) · Virologica Sinica · doi:10.1016/j.virs.2024.02.001 · Cited by 4 · see citing works

Research progress on the association between viruses and cardiac diseases

He-min, Y., Zhu, M.-L., Zhao, Y., Tan, J.-X., Luo, S.-C., Pang, P., & Zheng, C.-B. (2026) · Journal of Virology · doi:10.1128/jvi.00383-26 · Cited by 2 · see citing works

Respiratory viral infections and their role in human cardiovascular diseases

Ilyicheva, T. N., Sv, N., Abubakirova, O. A., & Gureyev, V. N. (2022) · Сибирский журнал клинической и экспериментальной медицины · doi:10.29001/2073-8552-2022-37-4-14-21 · Cited by 2 · see citing works

Infectious agents in dilated cardiomyopathy: Genetic interactions, autoimmunity, mechanisms, and therapeutic approaches

Zhang, J., Zhan, H., Xu, H., Wang, R., Li, Z., Feng, F., Wu, H., Xu, Z., Wang, S., Guo, Y., et al. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103860 · Cited by 1 · see citing works

Long-term effects of reovirus strain T3D on the myocardium

Azar, M. E. F., Zita, M. D., Keole, K. S., Rousseau, S. T., Cohen, C. D., Dai, D., Boehme, K., & Adamo, L. (2026) · Microbiology Spectrum · doi:10.1128/spectrum.02108-25 · Cited by 1 · see citing works

Enteroviruses Activate Cellular Innate Immune Responses Prior to Adaptive Immunity and Tropism Contributes to Severe Viral Pathogenesis

Coffman, J. A. (2025) · Microorganisms · doi:10.3390/microorganisms13040870 · Cited by 1 · see citing works

Respiratory viral infections and their role in human cardiovascular diseases

Ilyicheva, T. N., Sv, N., Abubakirova, O. A., & Gureyev, V. N. (2022) · Сибирский журнал клинической и экспериментальной медицины · doi:10.29001/2073-8552-2022-418

Immunogenicity and protective efficacy of an experimental inactivated coxsackievirus B3 vaccine based on a new candidate epidemic strain

Chen, J., Li, X., Yang, H., Chu, Z., Liu, J., Feng, C., & Ma, S. (2026) · Vaccine X · doi:10.1016/j.jvacx.2026.100897

Heart-specific T cell responses: from antigens to disease mechanisms

Ramos, G. C. (2026) · Nature Reviews Cardiology · doi:10.1038/s41569-026-01356-x

Autoimmune Mechanisms in Viral Myocarditis

Basavalingappa, R. H. (2018) · Lincoln (University of Nebraska)

Coxsackievirus B3 infection leads to the generation of cardiac myosin heavy chain-α-reactive CD4 T cells in A/J mice

Gangaplara, A., Massilamany, C., Brown, D. M., Delhon, G., Pattnaik, A. K., Chapman, N., Rose, N., Steffen, D., & Reddy, J. (2012) · Clinical Immunology · doi:10.1016/j.clim.2012.07.003 · Cited by 69 · see citing works

Cytoplasmic Proteins as Autoantigens in the Development of Inflammatory Heart Disease

Yalaka, B. (2017) · Lincoln (University of Nebraska)

Coxsackievirus B-3 myocarditis in Balb/c mice. Evidence for autoimmunity to myocyte antigens.

Huber, S. A., & Lodge, P. A. (1984) · PubMed · Cited by 242 · see citing works

Intricacies of cardiac damage in coxsackievirus B3 infection: Implications for therapy

Massilamany, C., Gangaplara, A., & Reddy, J. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.09.136 · Cited by 47 · see citing works