The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis
Open accessAbstract
Traumatic brain injury (TBI) represents a significant cause of death and disability in industrialized countries. Of particular importance to patients the chronic effect that TBI has on cognitive function. Therapeutic strategies have been difficult to evaluate because of the complexity of injuries and variety of patient presentations within a TBI population. However, pharmacotherapies targeting dopamine (DA) have consistently shown benefits in attention, behavioral outcome, executive function, and memory. Still it remains unclear what aspect of TBI pathology is targeted by DA therapies and what time-course of treatment is most beneficial for patient outcomes. Fortunately, ongoing research in animal models has begun to elucidate the pathophysiology of DA alterations after TBI. The purpose of this review is to discuss clinical and experimental research examining DAergic therapies after TBI, which will in turn elucidate the importance of DA for cognitive function/dysfunction after TBI as well as highlight the areas that require further study.
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Cites
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All’s well that transcribes well: Non-coding RNAs and post-stroke brain damage
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Chemokine CCL2 induces apoptosis in cortex following traumatic brain injury
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Hyperphosphorylated tau is implicated in acquired epilepsy and neuropsychiatric comorbidities.
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Rahmani, E., Lemelle, T. M., Samarbafzadeh, E., & Kablinger, A. S. (2021) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000656 · Cited by 43
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Metadata
- Authors
- Bales, J. W., Wagner, A. K., Kline, A. E., & Dixon, C. E.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2009-07
- Volume
- 33
- Issue
- 7
- Pages
- 981-1003
- ISSN
- 0149-7634 (ISSN-L)
- OpenAlex
- W2136942291
- Cited by
- 264
- References
- 29
- FWCI
- 9.46
- Type
- journal article
- Language
- en
- Open access
- green
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