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The neurocognitive consequences of sleep restriction: A meta-analytic review

Lowe, Cassandra J., Safati, Adrian, Hall, Peter A.·2017·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2017.07.010

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Abstract

The current meta-analytic review evaluated the effects of experimentally manipulated sleep restriction on neurocognitive functioning. Random-effects models were employed to estimate the overall effect size and the differential effect size across cognitive domains. Age, time of day, age-adjusted sleep deficit, cumulative days of restricted sleep, sleep latency, subjective sleepiness, and biological sex were examined as potential moderators of the effect. Based on a sample of 61 studies, from 71 different populations, findings revealed a significant negative effect of sleep restriction on cognitive processing across cognitive domains (g=-0.383, p<0.001). This effect held for executive functioning (g=-0.324, p<0.001), sustained attention (g=-0.409, p<0.001), and long-term memory (g=-0.192, p=0.002). There was insufficient evidence to detect an effect within the domains of attention, multitask, impulsive decision-making or intelligence. Age group, time of day, cumulative days of restricted sleep, sleep latency, subjective sleepiness, and biological sex were all significant moderators of the overall effect. In conclusion, the current meta-analysis is the first comprehensive review to provide evidence that short-term sleep restriction significantly impairs waking neurocognitive functioning.

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Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
The Unity and Diversity of Executive Functions and Their Contributions to Complex “Frontal Lobe” Tasks: A Latent Variable Analysis
Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter, A., & Wager, T. D. (2000) · Cognitive Psychology · doi:10.1006/cogp.1999.0734 · Cited by 15,798
Introduction to Meta‐Analysis
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009) · doi:10.1002/9780470743386 · Cited by 14,225
Introduction to Meta‐Analysis
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799
Untitled work
(2000) · Cited by 9,198
The attention system of the human brain
Posner, M. I., & Petersen, S. E. (1990) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.13.030190.000325 · Cited by 8,070
Human Memory: A Proposed System and its Control Processes
Atkinson, R. C., & Shiffrin, R. M. (1968) · Psychology of Learning and Motivation · doi:10.1016/s0079-7421(08)60422-3 · Cited by 7,216
The cognitive control of emotion
OCHSNER, K., & GROSS, J. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.03.010 · Cited by 4,495
Assessing heterogeneity in meta-analysis: Q statistic or I² index?
Huedo-Medina, T. B., Sánchez-Meca, J., Marín-Martínez, F., & Botella, J. (2006) · Psychological Methods · doi:10.1037/1082-989x.11.2.193 · Cited by 4,256
The Nature and Organization of Individual Differences in Executive Functions: Four General Conclusions
Miyake, A., & Friedman, N. P. (2012) · Current Directions in Psychological Science · doi:10.1177/0963721411429458 · Cited by 3,944

Show all 221 references

Research works printed but not linked: 1

National Sleep Foundation, 2010, Sleep in America, Poll, 2010

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Background
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Alqahtani, J. S., AlRabeeah, S. M., Aldhahir, A. M., Siraj, R. A., Aldabayan, Y. S., Alghamdi, S. M., Alqahtani, A., Alsaif, S. S., Naser, A. Y., & Alwafi, H. H. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19094940 · Cited by 48
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Marié, D., Müller, C. A. H., ALTENMÜLLER, E. O., Ville, D. V. D., Jünemann, K., Scholz, D. S., Krüger, T. H. C., Worschech, F., Kliegel, M., Sinke, C., et al. (2023) · Neuroimage Reports · doi:10.1016/j.ynirp.2023.100166 · Cited by 48
“As part of the extensive pre-screening demographic and health questionnaire, the average sleep duration in hours at baseline (subjective report) was inventoried, because the variability of sleep duration impacts executive function (Lowe et al., 2017).”
Background
The stress of losing sleep: Sex-specific neurobiological outcomes
Wright, C. J., Milosavljevic, S., & Pocivavsek, A. (2023) · Neurobiology of Stress · doi:10.1016/j.ynstr.2023.100543 · Cited by 46
“function of men to a greater extent than that of women (Lowe et al., 2017).”
Background
One night of sleep deprivation impairs executive function but does not affect psychomotor or motor performance
Skurvydas, A., Žlibinaitė, L., Solianik, R., Brazaitis, M., Valančienė, D., Baranauskienė, N., Majauskienė, D., Mickevičienė, D., Venckūnas, T., & Kamandulis, S. (2019) · Biology of Sport · doi:10.5114/biolsport.2020.89936 · Cited by 45
“Our data are consistent with a recent meta-analysis that reported that sleep restric - tion significantly impairs waking neurocognitive functions such as executive function, sustained attention, and long-term memory [30].”
Result
Economic Impact of Insufficient and Disturbed Sleep in the Workplace
Glick, D. R., Abariga, S. A., Thomas, I., Shipper, A. G., Gunia, B., Grandner, M. A., Rosenberg, E., Hines, S. E., Capaldi, V. F., Collen, J. F., et al. (2023) · PharmacoEconomics · doi:10.1007/s40273-023-01249-8 · Cited by 44
Sleep and circadian disruption in bipolar disorders: From psychopathology to digital phenotyping in clinical practice
Tonon, A. C., Nexha, A., da Silva, M. M., Gomes, F. A., Hidalgo, M. P. L., & Frey, B. N. (2024) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13729 · Cited by 51
Social network site addiction, sleep quality, depression and adolescent difficulty describing feelings: a moderated mediation model
Wang, J., Wang, N., Liu, P., & Liu, Y. (2025) · BMC Psychology · doi:10.1186/s40359-025-02372-1 · Cited by 45
Infant wake after sleep onset serves as a marker for different trajectories in cognitive development
Pisch, M., Wiesemann, F., & Karmiloff‐Smith, A. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12948 · Cited by 39
Effects of six weeks of chronic sleep restriction with weekend recovery on cognitive performance and wellbeing in high-performing adults
Smith, M. G., Wusk, G., Nasrini, J., Baskin, P., Dinges, D. F., Roma, P. G., & Basner, M. (2021) · SLEEP · doi:10.1093/sleep/zsab051 · Cited by 43
A dynamic attentional control framework for understanding sleep deprivation effects on cognition
Whitney, P. J., Hinson, J. M., & Nusbaum, A. T. (2019) · Progress in brain research · doi:10.1016/bs.pbr.2019.03.015 · Cited by 42
Napping and cognitive performance during night shifts: a systematic review and meta-analysis
Dutheil, F., Bessonnat, B., Pereira, B., Baker, J. S., Moustafa, F., Fantini, M. L., Mermillod, M., & Navel, V. (2020) · SLEEP · doi:10.1093/sleep/zsaa109 · Cited by 37
Neurocognitive Effects of Sleep Disruption in Children and Adolescents
Spruyt, K. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.08.003 · Cited by 41
Impaired Vigilant Attention Partly Accounts for Inhibition Control Deficits After Total Sleep Deprivation and Partial Sleep Restriction
Mao, T., Dinges, D. F., Deng, Y., Zhao, K., Yang, Z., Lei, H., Fang, Z., Yang, F. N., Galli, O., Goel, N., et al. (2021) · Nature and Science of Sleep · doi:10.2147/nss.s314769 · Cited by 43
“Due to the prevalence of sleep loss and the importance of inhibition control, many researchers have explored the effects of sleep disturbance or sleep deprivation on inhibition control.(14) For example, one previous event-related potentials (ERP) study found that poor sleep affects the speed to inhibit a motor respons…”
Sleep Health
Vorster, A. P. A., Someren, E. J. W. V., Pack, A. I., Huber, R., Schmidt, M. H., & Bassetti, C. L. (2024) · Clinical and Translational Neuroscience · doi:10.3390/ctn8010008 · Cited by 51
“Sleep deprivation or restriction acutely impairs executive function, information processing, visual-spatial perception, psychomotor skills, and performance [11].”
Background
The impact of five nights of sleep restriction on emotional reactivity
Tempesta, D., Salfi, F., Gennaro, L. D., & Ferrara, M. (2020) · Journal of Sleep Research · doi:10.1111/jsr.13022 · Cited by 37
Mechanistic insights into the interaction between epilepsy and sleep
Sheybani, L., Frauscher, B., Bernard, C., & Walker, M. C. (2025) · Nature Reviews Neurology · doi:10.1038/s41582-025-01064-z · Cited by 43
“Cognitive difficulties in epilepsy are multifactorial, and disturbances in sleep — particularly sleep efficiency (the proportion of sleep during the period spent in bed) — can play a part 164 to a similar degree as in people without epilepsy 165 .”
The acute effects of sleep restriction therapy for insomnia on circadian timing and vigilance
Maurer, L., Ftouni, S., Espie, C. A., Bisdounis, L., & Kyle, S. D. (2020) · Journal of Sleep Research · doi:10.1111/jsr.13260 · Cited by 36
“Indeed, the magnitude of impairment (ES 0.62–0.64) is comparable to healthy controls when undergoing experimental chronic sleep restriction (Lowe et al., 2017).”
BackgroundInfluential
Observing changes in human functioning during induced sleep deficiency and recovery periods
Ochab, J. K., Jerzy Szwed, A., Oleś, K., Beres, A. M., Chialvo, D. R., Domagalik, A., Fąfrowicz, M., Gudowska-Nowak, E., Marek, T., Nowak, M. A., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0255771 · Cited by 41
Using recreational cannabis to treat insomnia: Evidence from over-the-counter sleep aid sales in Colorado
Doremus, J. M., Stith, S. S., & Vigil, J. M. (2019) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.102207 · Cited by 34
Sleep in the Intensive Care Unit: Strategies for Improvement
Dorsch, J. J., Martin, J. L., Malhotra, A., Owens, R. L., & Kamdar, B. B. (2019) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0039-1698378 · Cited by 42
Activation of the Hippocampal LXRβ Improves Sleep-Deprived Cognitive Impairment by Inhibiting Neuroinflammation
Qiu, C., Wang, M., Yu, W., Rong, Z., Zheng, H.-S., Sun, T., Liu, S., Zhao, M., & Wu, Y. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02446-2 · Cited by 35
“SD pervasively links to numerous neurological and psychiatric disorders [3], and the high clinical incidence of SD seriously endangers public health and brings a great burden to society [4].”
Background
The effect of sleep restriction on cognitive performance in elite cognitive performers: a systematic review
Smithies, T. D., Toth, A. J., Dunican, I. C., Caldwell, J. A., Kowal, M., & Campbell, M. J. (2021) · SLEEP · doi:10.1093/sleep/zsab008 · Cited by 35
“Overall, the reference sections of five reviews and one annotated bibliography were searched for relevant studies [17, 29, 53–56].”
Influential
Fundamentals of sleep regulation: Model and benchmark values for fractal and oscillatory neurodynamics
Bódizs, R., Schneider, B., Ujma, P. P., Horváth, C. G., Dresler, M., & Rosenblum, Y. (2024) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2024.102589 · Cited by 39
“Experimental works revealed clear evidence for detrimental neurocognitive effects of cumulative sleep loss due to consecutive restrictions of sleep time (Lowe et al., 2017).”
Choline alleviates cognitive impairment in sleep-deprived young mice via reducing neuroinflammation and altering phospholipidomic profile
Huang, S., Yang, Z., Cheng, J., Li, H.-Y., Chen, S., Huang, Z.-H., Chen, J.-D., Xiong, R.-G., Yang, M.-T., Wang, C., et al. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103578 · Cited by 33
“Sleep plays a paramount role in cognition, influencing every level from cellular redox state regulation and neuronal structures to brain morphology and function [4,5].”
Mobile phone addiction was the mediator and physical activity was the moderator between bullying victimization and sleep quality
Peng, J., Wang, J., Chen, J., Li, G., Xiao, H., Liu, Y., Zhang, Q., Wu, X., & Zhang, Y. (2025) · BMC Public Health · doi:10.1186/s12889-025-22813-1 · Cited by 39
“These impacts include heightened risks of anxiety and depression [14], aggression [15], cognitive function changes [16], and suicidal behaviors [17], technology addiction [18, 19].”
Accuracy of diagnostic classification algorithms using cognitive-, electrophysiological-, and neuroanatomical data in antipsychotic-naïve schizophrenia patients
Ebdrup, B. H., Axelsen, M., Bak, N. K., Fagerlund, B., Oranje, B., Raghava, J. M., Nielsen, M. Ø., Rostrup, E., Hansen, L. K., & Glenthoj, B. Y. (2018) · Psychological Medicine · doi:10.1017/s0033291718003781 · Cited by 32
Expert Consensus on Screening and Assessment of Cognition in Psychiatry
McIntyre, R. S., Anderson, N. D., Baune, B. T., Brietzke, E. M., Burdick, K. E., Fossati, P., Gorwood, P. A. P. M., Harmer, C. J., Harrison, J., Harvey, P. D., et al. (2019) · CNS Spectrums · doi:10.1017/s1092852918001189 · Cited by 33
“Finally, maladaptive behaviors impacting cognition, notably disruption in sleep duration, efficiency, and/or reversal of day/night schedule should be ruled out as modifiable contributors of cognitive impairment.(49)”
Background
Effects of two nights of sleep deprivation on executive function and central and peripheral fatigue during maximal voluntary contraction lasting 60s
Skurvydas, A., Kazlauskaite, D., Žlibinaitė, L., Čekanauskaitė, A., Valančienė, D., Karanauskienė, D., Zuozienė, I. J., Majauskienė, D., Mickevičienė, D., & Šatas, A. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.113226 · Cited by 33
Associations of Dietary ω-3, ω-6 Fatty Acids Consumption with Sleep Disorders and Sleep Duration among Adults
Luo, J., Ge, H., Sun, J., Hao, K., Yao, W., & Zhang, D. (2021) · Nutrients · doi:10.3390/nu13051475 · Cited by 31
Sleep deficiency as a driver of cellular stress and damage in neurological disorders
Coulson, R. L., Mourrain, P., & Wang, G. X. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2022.101616 · Cited by 33
Sleep Quality and Cognitive Function after Stroke: The Mediating Roles of Depression and Anxiety Symptoms
Niu, S., Liu, X., Wu, Q., Ma, J., Wu, S., Zeng, L., & Shi, Y. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20032410 · Cited by 34
“Strong empirical evidence suggests that sleep deprivation can have serious consequences on cognitive function [37].”
Background
Individual sleep need is flexible and dynamically related to cognitive function
Fjell, A. M., & Walhovd, K. B. (2024) · Nature Human Behaviour · doi:10.1038/s41562-024-01827-6 · Cited by 40
“Sleep deprivation studies have established that sleep loss has acute negative effects on neurocognitive function and the brain 12,13,24–30 .”
Influential
Cumulative mild partial sleep deprivation negatively impacts working memory capacity but not sustained attention, response inhibition, or decision making: a randomized controlled trial
Santisteban, J. A., Brown, T. G., Ouimet, M. C., & Gruber, R. (2018) · Sleep Health · doi:10.1016/j.sleh.2018.09.007 · Cited by 32
Sleep, caregiver burden, and life satisfaction in Parkinson’s disease caregivers: a multinational investigation
Perez, E., Perrin, P. B., Lageman, S. K., Villaseñor, T., & Dzierzewski, J. M. (2020) · Disability and Rehabilitation · doi:10.1080/09638288.2020.1814878 · Cited by 31
“While caregiver burden may initially lead to difficulty sleeping, continued sleep difficulties may contribute to the maintenance of caregiver burden over time due to impaired cognitive and emotional functioning, factors sleep are known to impact and are needed to provide care for individuals with PD [45,46].”
Background
Physical Activity and Executive Function in Children With ADHD: The Mediating Role of Sleep
Liang, X., Li, R., Wong, S. H., Sum, R. K. W., Wang, P., Yang, B., & Sit, C. H. P. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2021.775589 · Cited by 34
Meeting 24-h movement behavior guidelines is linked to academic engagement, psychological functioning, and cognitive difficulties in youth with internalizing problems
Gao, Y., Yu, Q., Schuch, F. B., Herold, F., Hossain, M. M., Ludyga, S., Gerber, M., Mullen, S. P., Yeung, A., Kramer, A. F., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.017 · Cited by 35
The effects of sleep deprivation, acute hypoxia, and exercise on cognitive performance: A multi-experiment combined stressors study
Williams, T. B., Badariotti, J. I., Corbett, J., Dicks, M., Neupert, E. C., McMorris, T., Ando, S., Parker, M. O., Thelwell, R., Causer, A. J., et al. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114409 · Cited by 32
“For example, individuals who visit terrestrial high altitude are also likely to experience a disruption to their sleep [14,15]; Kupper et al., [16]; [17].”
A systematic and meta-analytic review of the impact of sleep restriction on memory formation
Crowley, R., Alderman, E., Javadi, A., & Tamminen, J. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105929 · Cited by 51
“…adaptive mechanism would compensate for prolonged sleep restriction in the long-term memory domain (Drake et al., 2001), a previous meta-analysis (Lowe et al., 2017) assessed the impact of 2 – 6 hours of sleep loss and found that the effect size associated with long-term memory was in fact…”
BackgroundMethodResultInfluential

Authors: Lowe, C. J., Safati, A., & Hall, P. A.
Affiliations: University of Waterloo (CA)
Corresponding author: Lowe, Cassandra J.
ORCID: Lowe, Cassandra J.
Safati, Adrian
Hall, Peter A.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2017-09
Volume: 80
Pages: 586-604
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2017.07.010
OpenAlex: W2741266150
Cited by: 520
References: 221
Citations by year: 2026: 63 · 2025: 86 · 2024: 75 · 2023: 60 · 2022: 69 · 2021: 65 · 2020: 42 · 2019: 35 · 2018: 23 · 2017: 2
FWCI: 4.41
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords: sleep restriction, neuropsychological performance, executive function, sustained attention, long-term memory, sleep deprivation, subjective sleepiness, sleep latency, age differences, sex differences, time of day
MeSH terms: Cognition, Humans, Sleep, Sleep Deprivation

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The neurocognitive consequences of sleep restriction: A meta-analytic review

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