Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats

Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path

Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,460 · see citing works

Short-Term Synaptic Plasticity

Zucker, R. S., & Regehr, W. G. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.092501.114547 · Cited by 5,068 · see citing works

Cloned Glutamate Receptors

Hollmann, M., & Heinemann, S. F. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.000335 · Cited by 4,011 · see citing works

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640 · see citing works

Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes.

Engvall, E., & Perlmann, P. (1972) · PubMed · Cited by 3,122 · see citing works

Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus

Collingridge, G. L., Kehl, S. J., & McLennan, H. (1983) · The Journal of Physiology · doi:10.1113/jphysiol.1983.sp014478 · Cited by 2,413 · see citing works

Genetic enhancement of learning and memory in mice

Tang, Y., Shimizu, E., Dubé, G., Rampon, C., Kerchner, G. A., Zhuo, M., Liu, G., & Tsien, J. Z. (1999) · Nature · doi:10.1038/43432 · Cited by 1,867 · see citing works

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory.

Tsien, J. Z., Huerta, P. T., & Tonegawa, S. (1996) · Cell · doi:10.1016/s0092-8674(00)81827-9 · Cited by 1,782 · cited 2× · see citing works

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

Mulkey, R. M., & Malenka, R. C. (1992) · Neuron · doi:10.1016/0896-6273(92)90248-c · Cited by 1,113 · see citing works

Role of NMDA Receptor Subtypes in Governing the Direction of Hippocampal Synaptic Plasticity

Liu, L., Wong, T. P., Pozza, M. F., Lingenhoehl, K., Wang, Y., Sheng, M., Auberson, Y. P., & Wang, Y. T. (2004) · Science · doi:10.1126/science.1096615 · Cited by 1,106 · see citing works

Impaired Spatial Learning after Saturation of Long-Term Potentiation

Moser, E. I., Krobert, K. A., Moser, M.-B., & Morris, R. G. M. (1998) · Science · doi:10.1126/science.281.5385.2038 · Cited by 505 · see citing works

Expression of Cerebellar Long-Term Depression Requires Postsynaptic Clathrin-Mediated Endocytosis

Wang, Y. T., & Linden, D. J. (2000) · Neuron · doi:10.1016/s0896-6273(00)81066-1 · Cited by 484 · see citing works

Circuit-Specific Alterations in Hippocampal Synaptophysin Immunoreactivity Predict Spatial Learning Impairment in Aged Rats

Smith, T. D., Adams, M., Gallagher, M., Morrison, J., & Rapp, P. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-17-06587.2000 · Cited by 404 · see citing works

Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain

Åberg, N. D., Brywe, K. G., & Isgaard, J. (2006) · The Scientific World JOURNAL · doi:10.1100/tsw.2006.22 · Cited by 387 · see citing works

An evaluation of spatial information processing in aged rats.

Rapp, P. R., Rosenberg, R. A., & Gallagher, M. (1987) · Behavioral Neuroscience · doi:10.1037/0735-7044.101.1.3 · Cited by 355 · see citing works

Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats

Fischer, W., Gage, F. H., & Björklund, A. (1989) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1989.tb00772.x · Cited by 334 · see citing works

Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information

McNaughton, B. L., Barnes, C. A., RAO, G. R., Baldwin, J., & Rasmussen, M. (1986) · Journal of Neuroscience · doi:10.1523/jneurosci.06-02-00563.1986 · Cited by 327 · see citing works

Age-related spatial reference and working memory deficits assessed in the water maze

Frick, K. M., Baxter, M. G., Markowska, A. L., Olton, D. S., & Price, D. L. (1995) · Neurobiology of Aging · doi:10.1016/0197-4580(94)00155-3 · Cited by 317 · see citing works

Decreased Pulsatile Release of Growth Hormone in Old Male Rats*

Sonntag, W. E., Steger, R. W., FORMAN, L. J., & Meites, J. (1980) · Endocrinology · doi:10.1210/endo-107-6-1875 · Cited by 276 · see citing works

Insulin-like growth factor-1 ameliorates age-related behavioral deficits

Markowska, A. L., Mooney, M., & Sonntag, W. E. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00143-2 · Cited by 270 · see citing works

A Hippocampal NR2B Deficit Can Mimic Age-Related Changes in Long-Term Potentiation and Spatial Learning in the Fischer 344 Rat

Clayton, D. A., Mesches, M. H., Álvarez, E., Bickford, P. C., & Browning, M. D. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03628.2002 · Cited by 258 · see citing works

Localization and ontogeny of growth hormone receptor gene expression in the central nervous system

Lobie, P. E., García-Aragón, J., Lincoln, D. T., Barnard, R. T., Wilcox, J. N., & Waters, M. J. (1993) · Developmental Brain Research · doi:10.1016/0165-3806(93)90008-x · Cited by 222 · see citing works

Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects

Jl, T., Piriz, J., Llorens-Martı́n, M., Fernandez, A. M., Bolós, M., LeRoith, D., Núñez, Á., & Torres‐Alemán, I. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002076 · Cited by 210 · see citing works

Hippocampal function and behavior: Spatial discrimination and response inhibition

Olton, D. S., & Werz, M. A. (1978) · Physiology & Behavior · doi:10.1016/0031-9384(78)90252-4 · Cited by 210 · see citing works

Aging Changes in Voltage-Gated Calcium Currents in Hippocampal CA1 Neurons

Campbell, L. W., Hao, S., Thibault, O., Blalock, E. M., & Landfield, P. W. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-19-06286.1996 · Cited by 199 · see citing works

Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression

Eckles-Smith, K., Clayton, D. A., Bickford, P. C., & Browning, M. D. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00088-7 · Cited by 194 · see citing works

Recovery of spatial learning deficits after decay of electrically induced synaptic enhancement in the hippocampus

Castro, C. A., Silbert, L. H., McNaughton, B. L., & Barnes, C. A. (1989) · Nature · doi:10.1038/342545a0 · Cited by 186 · see citing works

Long‐term potentiation and N‐methyl‐D‐aspartate receptors in the visual cortex of young rats.

Kimura, F., Nishigori, A., Shirokawa, T., & Tsumoto, T. (1989) · The Journal of Physiology · doi:10.1113/jphysiol.1989.sp017680 · Cited by 185 · see citing works

Structural Contributions to Short-Term Synaptic Plasticity

Xu‐Friedman, M. A., & Regehr, W. G. (2004) · Physiological Reviews · doi:10.1152/physrev.00016.2003 · Cited by 178 · see citing works

Maintenance of superior learning and memory function in NR2B transgenic mice during ageing

Cao, X., Cui, Z., Feng, R., Tang, Y., Qin, Z., Mei, B., & Tsien, J. Z. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05431.x · Cited by 171 · see citing works

Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability

Adams, M. M., Shi, L., Linville, M. C., Forbes, M. E., Long, A. B., Bennett, C., Newton, I. G., Carter, C. S., Sonntag, W. E., Riddle, D. R., et al. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.01.016 · Cited by 170 · see citing works

Vestibular-hippocampal interactions

Smith, P. F. (1997) · Hippocampus · doi:10.1002/(sici)1098-1063(1997)7:5 · Cited by 170 · see citing works

Spatial Learning and Memory Deficits after Whole-Brain Irradiation are Associated with Changes in NMDA Receptor Subunits in the Hippocampus

Shi, L., Adams, M. M., Long, A. B., Carter, C. C., Bennett, C., Sonntag, W. E., Nicolle, M. M., Robbins, M., D'Agostino, R., & Brunso‐Bechtold, J. K. (2006) · Radiation Research · doi:10.1667/rr0588.1 · Cited by 166 · see citing works

Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions

Thibault, O., Porter, N. M., Chen, K.-C., Blalock, E. M., Kaminker, P. G., Clodfelter, G. V., Brewer, L. D., & Landfield, P. W. (1998) · Cell Calcium · doi:10.1016/s0143-4160(98)90064-1 · Cited by 165 · see citing works

Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons

Burton, K. A., Kabigting, E. B., Clifton, D. K., & Steiner, R. A. (1992) · Endocrinology · doi:10.1210/endo.131.2.1353444 · Cited by 165 · see citing works

Insulin-Like Growth Factor I

Kooijman, R., Sarre, S., Michotte, Y. M., & Keyser, J. D. (2009) · Stroke · doi:10.1161/strokeaha.108.528356 · Cited by 152 · see citing works

Permeation of Growth Hormone across the Blood-Brain Barrier

Pan, W., Yu, Y., Cain, C. M., Nyberg, F., Couraud, P. O., & Kastin, A. J. (2005) · Endocrinology · doi:10.1210/en.2005-0587 · Cited by 149 · see citing works

Age-Related Decrease in the N-Methyl-d-AspartateR-Mediated Excitatory Postsynaptic Potential in Hippocampal Region CA1

Barnes, C. A., RAO, G. R., & Shen, J. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00044-4 · Cited by 145 · see citing works

Differential effects and rates of normal aging in cerebellum and hippocampus

Woodruff-Pak, D. S., Foy, M. R., Akopian, G. G., Lee, K. H., Zach, J., Nguyen, K. P. T., Comalli, D. M., Kennard, J. A., Agelan, A., & Thompson, R. F. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914207107 · Cited by 143 · see citing works

Learning-specific, time-dependent increases in hippocampal Ca2+/calmodulin-dependent protein kinase II activity and AMPA GluR1 subunit immunoreactivity

Cammarota, M., Bernabeu, R., de Stein, M. L., Izquierdo, I., & Medina, J. H. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00254.x · Cited by 141 · see citing works

Age and insulin-like growth factor-1 modulate N-methyl-D-aspartate receptor subtype expression in rats

Sonntag, W. E., Bennett, S. A., Khan, A. S., Thornton, P. L., Xu, X., Ingram, R. L., & Brunso‐Bechtold, J. K. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(99)00259-2 · Cited by 140 · see citing works

Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

Bliss, T. V. P., & Lømo, T. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010273 · Cited by 135 · see citing works

Neuronal activity differentially regulates NMDA receptor subunit expression in cerebellar granule cells

Vallano, M. L., Lambolez, B., Audinat, É., & Rossier, J. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00631.1996 · Cited by 134 · see citing works

Role of the Growth Hormone/Insulin-Like Growth Factor 1 Axis in Neurogenesis

Åberg, N. D. (2009) · Endocrine development · doi:10.1159/000262529 · Cited by 125 · see citing works

Activation of the spinal sigma‐1 receptor enhances NMDA‐induced pain via PKC‐ and PKA‐dependent phosphorylation of the NR1 subunit in mice

Kim, H., Roh, D., Yoon, S., Seo, H., Kwon, Y., Han, H. J., Kim, K.-W., Beitz, A. J., & Lee, J. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.159 · Cited by 121 · see citing works

Aging of glutamate receptors: correlations between binding and spatial memory performance in mice

Magnusson, K. R. (1998) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(98)00076-1 · Cited by 114 · see citing works

Growth hormone induces age-dependent alteration in the expression of hippocampal growth hormone receptor and N -methyl- d -aspartate receptor subunits gene transcripts in male rats

Grevès, M. L., Steensland, P., Grevès, P. L., & Nyberg, F. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092135399 · Cited by 113 · see citing works

Hippocampal dependent learning ability correlates with N‐methyl‐D‐aspartate (NMDA) receptor levels in CA3 neurons of young and aged rats

Adams, M. M., Smith, T. D., Moga, D. E., Gallagher, M., Wang, Y., Wolfe, B. B., Rapp, P. R., & Morrison, J. H. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1099 · Cited by 111 · see citing works

Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment-related gene expression in rats

Zhao, X., Sun, L., Jia, H., Meng, Q., Wu, S., Li, N., & He, S. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.06.016 · Cited by 105 · see citing works

Activity‐dependent Regulation of N‐Methyl‐ d ‐aspartate Receptor Subunit Expression in Rat Cerebellar Granule Cells

Audinat, É., Lambolez, B., Rossier, J., & Crépel, F. (1994) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1994.tb00572.x · Cited by 103 · see citing works

Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning

Ramsey, M. M., Weiner, J. L., Moore, T. P., Carter, C. S., & Sonntag, W. E. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.08.001 · Cited by 101 · see citing works

Synaptic plasticity in early aging

LYNCH, G. S., Rex, C. S., & Gall, C. M. (2006) · Ageing Research Reviews · doi:10.1016/j.arr.2006.03.008 · Cited by 97 · see citing works

Functional Characterization of Des-IGF-1 Action at Excitatory Synapses in the CA1 Region of Rat Hippocampus

Ramsey, M. M., Adams, M. M., Ariwodola, O. J., Sonntag, W. E., & Weiner, J. L. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00768.2004 · Cited by 94 · see citing works

Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis

Shi, L., Adams, M. M., Linville, M. C., Newton, I. G., Forbes, M. E., Long, A. B., Riddle, D. R., & Brunso‐Bechtold, J. K. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.03.026 · Cited by 78 · see citing works

Growth Hormone Enhances Excitatory Synaptic Transmission in Area CA1 of Rat Hippocampus

Mahmoud, G. S., & Grover, L. M. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00947.2005 · Cited by 73 · see citing works

Characterization of growth hormone binding sites in rat brain

Zhai, Q., Lai, Z., Roos, P., & Nyberg, F. (1994) · Acta Paediatrica · doi:10.1111/j.1651-2227.1994.tb13433.x · Cited by 71 · see citing works

Aging Effects on the Limits and Stability of Long-Term Synaptic Potentiation and Depression in Rat Hippocampal Area CA1

Kumar, A., Thinschmidt, J. S., Foster, T. C., & King, M. A. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00249.2007 · Cited by 69 · see citing works

Protective and regenerative effects of the GH/IGF-I axis on the brain.

Isgaard, J., Åberg, N. D., & Nilsson, M. D. (2007) · PubMed · Cited by 63 · see citing works

The distribution of lactogen receptors in the mammalian hypothalamus: an in vitro autoradiographic analysis of the rabbit and rat

Walsh, R. J., Mangurian, L. P., & Posner, B. I. (1990) · Brain Research · doi:10.1016/0006-8993(90)90651-q · Cited by 58 · see citing works

Insulin acts as a somatomedin analog in stimulating myoblast growth in serum-free medium

Florini, J. R., & Ewton, D. Z. (1981) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/bf02618442 · Cited by 56 · see citing works

Caloric restriction does not reverse aging-related changes in hippocampal BDNF

Newton, I. G., Forbes, M. E., Legault, C., Johnson, J. E., Brunso‐Bechtold, J. K., & Riddle, D. R. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.06.005 · Cited by 55 · see citing works

Growth hormone, insulin-like growthfactor I and the CNS: Localization, function and mechanism of action

Lobiezz, P. E., Zhu, T., Graichen, R., & Goh, E. L. K. (2000) · Growth Hormone & IGF Research · doi:10.1016/s1096-6374(00)80010-6 · Cited by 52 · see citing works

Peripheral growth hormone induces cell proliferation in the intact adult rat brain

Åberg, N. D., Lind, J., Isgaard, J., & Kuhn, H. G. (2010) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2009.12.003 · Cited by 50 · see citing works

Effects of aging and caloric restriction on dentate gyrus synapses and glutamate receptor subunits

Newton, I. G., Forbes, M. E., Linville, M. C., Hui, P., Tucker, E. W., Riddle, D. R., & Brunso‐Bechtold, J. K. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.03.009 · Cited by 50 · see citing works

CaM kinase II and protein kinase C activations mediate enhancement of long‐term potentiation by nefiracetam in the rat hippocampal CA1 region

Moriguchi, S., Shioda, N., Han, F., Narahashi, T., & Fukunaga, K. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05440.x · Cited by 35 · see citing works

Growth hormone receptors in hypothalamic and extra-hypothalamic tissues

Fräser, R. A., Attardo, D., & Harvey, S. (1990) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0050231 · Cited by 33 · see citing works

Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca 2+ and insulin secretion

Zhang, F., Zhang, Q., Tengholm, A., & Sjöholm, Å. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00418.2005 · Cited by 31 · see citing works

Activation of corticostriatal pathway leads to similar morphological changes observed following haloperidol treatment

Meshul, C. K., Buckman, J. F., Allen, C., Riggan, J. P., & Feller, D. J. (1996) · Synapse · doi:10.1002/(sici)1098-2396(199604)22:4 · Cited by 30 · see citing works

Stability of local brain levels of insulin-like growth factor-I in two well-characterized models of decreased plasma IGF-I

Adams, M. M., Forbes, M. E., Linville, M. C., Riddle, D. R., Sonntag, W. E., & Brunso‐Bechtold, J. K. (2009) · Growth Factors · doi:10.1080/08977190902863639 · Cited by 26 · see citing works

Autoregulation of growth hormone receptor and growth hormone binding protein transcripts in brain and peripheral tissues of the rat

Hull, K., & Harvey, S. A. K. (1998) · Growth Hormone & IGF Research · doi:10.1016/s1096-6374(98)80107-x · Cited by 18 · see citing works

Insulin-like growth factor I and cardiac performance in heart failure

Donath, M. Y., Froesch, E. R., & Zapf, J. (1998) · Growth Hormone & IGF Research · doi:10.1016/s1096-6374(98)80045-2 · Cited by 13 · see citing works

Growth hormone, insulin-like growth factor-1 and the aging brain

Ashpole, N. M., Sanders, J. E., Hodges, E. L., Han, Y., & Sonntag, W. E. (2014) · Experimental Gerontology · doi:10.1016/j.exger.2014.10.002 · Cited by 226 · see citing works

Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach

Tanriverdi, F., Schneider, H. J., Aimaretti, G., Masel, B. E., Casanueva, F. F., & Kelestimur, F. (2015) · Endocrine Reviews · doi:10.1210/er.2014-1065 · Cited by 218 · see citing works

Isolated Growth Hormone Deficiency (GHD) in Childhood and Adolescence: Recent Advances

Alatzoglou, K. S., Webb, E. A., Tissier, P. L., & Dattani, M. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1067 · Cited by 155 · see citing works

Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity

Vints, W. A. J., Levin, O., Fujiyama, H., Verbunt, J., & Masiulis, N. (2022) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2022.100993 · Cited by 114 · see citing works

Central Regulation of Metabolism by Growth Hormone

Donato, J., Wasinski, F., Furigo, I. C., Metzger, M., & Frazão, R. (2021) · Cells · doi:10.3390/cells10010129 · Cited by 87 · see citing works

Expression and function of growth hormone in the nervous system: A brief review

Arámburo, C., Betancourt, C. A., Luna, M., & Harvey, S. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.04.035 · Cited by 55 · see citing works

The effects of repeat traumatic brain injury on the pituitary in adolescent rats

Greco, T., Hovda, D., & Prins, M. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2013.2990 · Cited by 51 · see citing works

Growth Hormone (GH) and Gonadotropin-Releasing Hormone (GnRH) in the Central Nervous System: A Potential Neurological Combinatory Therapy?

Martínez-Moreno, C. G., Calderón-Vallejo, D., Harvey, S., Arámburo, C., & Quintanar, J. L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020375 · Cited by 51 · see citing works

Restoration of hippocampal growth hormone reverses stress-induced hippocampal impairment

Weele, C. M. V., Saenz, C., Yao, J., Correia, S. S., & Goosens, K. A. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00066 · Cited by 41 · see citing works

Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats

Molina, D. P., Ariwodola, O. J., Weiner, J. L., Brunso‐Bechtold, J. K., & Adams, M. M. (2012) · AGE · doi:10.1007/s11357-012-9460-4 · Cited by 41 · see citing works

Pituitary and/or hypothalamic dysfunction following moderate to severe traumatic brain injury: Current perspectives

Javed, Z., Qamar, U., & Sathyapalan, T. (2015) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.167561 · Cited by 37 · see citing works

IGF-1 facilitates extinction of conditioned fear

Noriega‐Prieto, J. A., Maglio, L. E., Maroto, I. B., Martín-Cortecero, J., Muñoz‐Callejas, A., Callejo-Móstoles, M., & de Sevilla, D. F. (2021) · eLife · doi:10.7554/elife.67267 · Cited by 33 · see citing works

Astrocytic IGF-IRs Induce Adenosine-Mediated Inhibitory Downregulation and Improve Sensory Discrimination

Noriega‐Prieto, J. A., Maglio, L. E., Zegarra-Valdivia, J. A., Pignatelli, J., Fernandez, A. M., Martinez‐Rachadell, L., Fernandes, J., Núñez, Á., Araque, A., Torres‐Alemán, I., et al. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0005-21.2021 · Cited by 35 · see citing works

Distribution of growth hormone-responsive cells in the brain of rats and mice

Wasinski, F., Klein, M., Bittencourt, J. C., Metzger, M., & Donato, J. (2020) · Brain Research · doi:10.1016/j.brainres.2020.147189 · Cited by 30 · see citing works

New findings on brain actions of growth hormone and potential clinical implications

Donato, J., & Kopchick, J. J. (2023) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09861-x · Cited by 31 · see citing works

Cognitive improvement by acute growth hormone is mediated by NMDA and AMPA receptors and MEK pathway

Ramis, M. R., Sarubbo, F., Solà, J., Aparicio, S., Garau, C., Miralles, A., & Esteban, S. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.04.005 · Cited by 30 · see citing works

Research progress on the role of hormones in ischemic stroke

Huang, S., Liu, L., Tang, X., Xie, S., Li, X., Kang, X., & Zhu, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1062977 · Cited by 27 · see citing works

Neuronal Plasticity and Age-Related Functional Decline in the Motor Cortex

Inoue, R., & Nishimune, H. (2023) · Cells · doi:10.3390/cells12172142 · Cited by 25 · see citing works

A clinical and pathophysiological approach to traumatic brain injury-induced pituitary dysfunction

Temizkan, Ş., & Keleştimur, F. (2019) · Pituitary · doi:10.1007/s11102-019-00941-3 · Cited by 24 · see citing works

Decreased Insulin-Like Growth Factor-I and Its Receptor Expression in the Hippocampus and Somatosensory Cortex of the Aged Mouse

Lee, C. H., Ahn, J. H., Park, J. H., Yan, B. C., Kim, I. H., Lee, D. H., Cho, J.-H., Chen, B. H., Lee, J., Cho, J. H., et al. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1269-3 · Cited by 21 · see citing works

Growth hormone (GH) increases cognition and expression of ionotropic glutamate receptors (AMPA and NMDA) in transgenic zebrafish (Danio rerio)

Studzinski, A. L. M., Barros, D. M., & Marins, L. F. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.07.054 · Cited by 20 · see citing works

Biomarkers of Hippocampal Gene Expression in a Mouse Restraint Chronic Stress Model

Ubaldi, M., Ricciardelli, E., Pasqualini, L., Sannino, G., Soverchia, L., Ruggeri, B., Falcinelli, S., Renzi, A., Ludka, C., Ciccocioppo, R., et al. (2015) · Pharmacogenomics · doi:10.2217/pgs.15.3 · Cited by 18 · see citing works

Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

Lucas, D., Delgado-Garcia, J. M., Escudero, B., Albo, C., Aza, A., Acín‐Pérez, R., Torres, Y., Moreno-Murciano, P., Enrı́quez, J. A., Samper, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053243 · Cited by 16 · see citing works

Growth Hormone (GH) Enhances Endogenous Mechanisms of Neuroprotection and Neuroplasticity after Oxygen and Glucose Deprivation Injury (OGD) and Reoxygenation (OGD/R) in Chicken Hippocampal Cell Cultures

Olivares‐Hernández, J. D., Balderas-Márquez, J. E., Carranza, M., Luna, M., Martínez-Moreno, C. G., & Arámburo, C. (2021) · Neural Plasticity · doi:10.1155/2021/9990166 · Cited by 16 · see citing works

Intracerebroventricular administration of growth hormone induces morphological changes in pyramidal neurons of the hippocampus and prefrontal cortex in adult rats

Olivares‐Hernández, J. D., García‐García, F., Camacho‐Abrego, I., Flores, G., & Juárez‐Aguilar, E. (2018) · Synapse · doi:10.1002/syn.22030 · Cited by 14 · see citing works

Hippocampal growth hormone modulates relational memory and the dendritic spine density in CA1Preprint

Haugland, K. G., Olberg, A., Lande, A., Kjelstrup, K. B., & Brun, V. H. (2020) · Learning & Memory · doi:10.1101/lm.050229.119 · Cited by 11 · see citing works

Do neurosteroids have impact on depression and cognitive functions in cases with acromegaly?

Hatipoğlu, E., Hacıoğlu, Y., Polat, Y., Arslan, H. F., Öner, S., Ekmekçi, Ö. B., & Niyazoğlu, M. (2022) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2022.101496 · Cited by 9 · see citing works

Novel object recognition is not affected by age despite age-related brain changes

Aktoprak, I., Dinc, P., Günay, G., & Adams, M. M. (2013) · World Journal of Neuroscience · doi:10.4236/wjns.2013.34036 · Cited by 4 · see citing works

The role of growth hormone in hippocampal function

Juárez‐Aguilar, E., Olivares‐Hernández, J. D., Regalado‐Santiago, C., & García‐García, F. (2022) · Vitamins and hormones · doi:10.1016/bs.vh.2021.11.007 · Cited by 3 · see citing works

Cognitive Dysfunction in Depression: Lessons Learned from Animal Models

Réus, G. Z., Abelaira, H. M., Leffa, D. D., & Quevedo, J. (2015) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666141130223453 · Cited by 3 · see citing works

Evaluation of the anticonvulsant and neuroprotective effect of intracerebral administration of growth hormone in rats

Zamora-Bello, I., Martínez, A. L., Beltrán‐Parrazal, L., Roque, I. S., Juárez‐Aguilar, E., & López‐Meraz, M. L. (2021) · Neurología · doi:10.1016/j.nrl.2021.03.010 · Cited by 2 · see citing works

Influence of growth hormone replacement on neurological and psychomotor development. Case report

Motta, F., Eisencraft, A. P., & Crisostomo, L. G. (2018) · Einstein (São Paulo) · doi:10.1590/s1679-45082018rc3961 · Cited by 2 · see citing works

Growth Hormone Alters Remapping in the Hippocampal Area CA1 in a Novel Environment

Haugland, K. G., Jordbræk, S. V., Knutsen, E., Kjelstrup, K. B., & Brun, V. H. (2025) · eNeuro · doi:10.1523/eneuro.0237-24.2024 · Cited by 1 · see citing works

Interacción entre la hormona del crecimiento y el sistema glutamatérgico: implicaciones para la plasticidad cerebral

Zamora-Bello, I., & López‐Meraz, M. L. (2020) · eNeurobiología · doi:10.25009/eb.v11i28.2560

Evaluation of the anticonvulsant and neuroprotective effect of intracerebral administration of growth hormone in rats

Zamora-Bello, I., Martínez, A. L., Beltrán‐Parrazal, L., Roque, I. S., Juárez‐Aguilar, E., & López‐Meraz, M. L. (2023) · Neurología (English Edition) · doi:10.1016/j.nrleng.2023.12.003

Studies on the effect of growth hormone on age-related changes in glutamatergic transmission in the hippocampus

Molina, D. P. (2010) · WakeSpace Scholarship (Wake Forest University)

Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats

Molina, D. P., Ariwodola, O. J., Weiner, J. L., Brunso‐Bechtold, J. K., & Adams, M. M. (2012) · AGE · doi:10.1007/s11357-012-9460-4 · Cited by 41 · see citing works

Growth Hormone Enhances Excitatory Synaptic Transmission in Area CA1 of Rat Hippocampus

Mahmoud, G. S., & Grover, L. M. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00947.2005 · Cited by 73 · see citing works

Address for correspondence and reprints:

Mahmoud, G. S., Grover, L. M., & Grover, L. M. (2013)

Dynamic regulation of excitatory and inhibitory synaptic transmission by growth hormone in the developing mouse brain

Li, G., Wu, Q.-Z., Song, T.-J., Zhen, X.-C., & Yu, X. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-022-01027-w · Cited by 11 · see citing works