Stimulation on Demand: Closing the Loop on Deep Brain Stimulation
Open accessAbstract
High-frequency open-loop deep brain stimulation (DBS) has been used to alleviate Parkinson's symptoms for almost 20 years. In this issue of Neuron, Rosin et al. present a closed-loop real-time approach that improves DBS and shines light on the etiology of motor symptoms in Parkinson's disease.
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Closed-loop DBS has been proposed to deliver adaptive neuromodulation synchronized to each patient's real-time pathological brain state.
“Closed-loop DBS has been proposed to provide synchronous adaptive neuromodulation based on real-time pathological brain states in each patient [15, 83, 121].”
From Implantable neurotechnologies: a review of integrated circuit neural amplifiers (2016) · cites this paper as [121]
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- Authors
- Santos, F. J., Costa, R. M., & Tecuapetla, F.
- Affiliations
- Instituto Gulbenkian de Ciência (PT)
- Corresponding author
- Costa, Rui M.
- Tecuapetla, Fatuel
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2011-10
- Volume
- 72
- Issue
- 2
- Pages
- 197-198
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2062918171
- Cited by
- 60
- References
- 15
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 4 · 2022: 2 · 2021: 3 · 2020: 7 · 2019: 3 · 2018: 19 · 2017: 1 · 2016: 4 · 2015: 5 · 2014: 8 · 2013: 2
- FWCI
- 2.03
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Keywords
- deep brain stimulation, closed-loop stimulation, Parkinson's disease, real-time feedback, motor symptoms, high-frequency stimulation, closed-loop DBS
- MeSH terms
- Animals, Basal Ganglia, Globus Pallidus, Parkinson Disease, Secondary, Deep Brain Stimulation
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