Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
Montagne, Axel, Barnes, Samuel R., Sweeney, Melanie D., Halliday, Matthew R., Sagare, Abhay P., Zhao, Zhen, Toga, Arthur W., Jacobs, Russell E., Liu, Collin Y., Amezcua, Lilyana, Harrington, Michael G., Chui, Helena C., Law, Meng, Zlokovic, Berislav V.·2015·Neuron
Cited by (1,005)
Items 501–600 of 1,005
- Pushing the boundaries of brain organoids to study Alzheimer’s diseaseJonas Cerneckis, Guojun Bu, Yanhong Shi · 2023 · Trends in Molecular Medicine
- Assessing blood-brain barrier dysfunction and its association with Alzheimer’s pathology, cognitive impairment and neuroinflammationLukas Preis, Kersten Villringer, Frederic Brosseron, Emrah Düzel, Frank Jessen, Gabor C. Petzold, Alfredo Ramírez, Annika E. Spottke, Jochen B. Fiebach, Oliver Peters · 2024 · Alzheimer s Research & Therapy
- Targeting uric acid: a promising intervention against oxidative stress and neuroinflammation in neurodegenerative diseasesLin Xu, Chengwei Li, Tiantian Wan, Xinyi Sun, Xiaojie Lin, Dong Yan, Jianjun Li, Penghui Wei · 2025 · Cell Communication and Signaling
- New Insight Into the Pathogenesis of Cerebral Small-Vessel DiseasesKristin Müller, Gilles Courtois, Matilde Valeria Ursini, Markus Schwaninger · 2017 · Stroke
- Metabolic Syndrome and the Cellular Phase of Alzheimer's DiseaseSubbiah Pugazhenthi · 2017 · Progress in molecular biology and translational science
- The blood-brain barrier and methamphetamine: open sesame?Turowski, Patric, Kenny, Bridget-Ann · 2015 · Frontiers in Neuroscience
- Regionally specified human pluripotent stem cell-derived astrocytes exhibit different molecular signatures and functional propertiesRobert A. Bradley, Jack M. Shireman, Caya McFalls, Jeea Choi, Scott Glen Canfield, Yi Wei Dong, Katie A. Liu, Brianne Lisota, Jeffrey R. Jones, Andrew J. Petersen et al. · 2019 · Development
- Palmitic Acid and Oleic Acid Differently Modulate TLR2-Mediated Inflammatory Responses in Microglia and MacrophagesHowe, Anne-Marie, Burke, Sinéad, O’Reilly, Marcella E., McGillicuddy, Fiona C., Costello, Derek A. · 2022 · Molecular Neurobiology
- Neuroinflammation associated with ultrasound-mediated permeabilization of the blood–brain barrierOlive Jung, Alec Thomas, Scott Robert Burks, Michael Loran Dustin, Joseph Alan Frank, Marc Ferrer, Eleanor Stride · 2022 · Trends in Neurosciences
- The COVID-19 pandemic and Alzheimer’s disease: mutual risks and mechanismsFeng Chen, Yan‐Ting Chen, Yongxiang Wang, Qiongwei Ke, Lili Cui · 2022 · Translational Neurodegeneration
- Cell type-specific changes identified by single-cell transcriptomics in Alzheimer’s diseaseTain Luquez, Pallavi Gaur, Ivy M Kosater, Matti Lam, Dylan I. Lee, Jason A. Mares, Fahad Paryani, Archana Yadav, Vilas Menon · 2022 · Genome Medicine
- Rescue of Alzheimer’s disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cellsPriyanka Mishra, Alexander Silva, Jay Sharma, Jacqueline Nguyen, Donald P. Pizzo, Denise Hinz, Debashis Sahoo, Stéphanie Cherqui · 2023 · Cell Reports
- Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged miceMiranda, André Miguel, Ashok, Archana, Chan, Robin Barry, Zhou, Bowen, Xu, Yimeng, McIntire, Laura Beth, Area-Gomez, Estela, Di Paolo, Gilbert, Duff, Karen E., Oliveira, Tiago Gil et al. · 2022 · Translational Psychiatry
- Hippocampal proteomic analysis reveals the disturbance of synaptogenesis and neurotransmission induced by developmental exposure to organophosphate flame retardant triphenyl phosphateZhong, Xiali, Yu, Yuejin, Wang, Can, Zhu, Qicheng, Wu, Jingwei, Ke, Weijian, Ji, Di, Niu, Congying, Yang, Xifei, Wei, Yanhong · 2021 · Journal of Hazardous Materials
- Pericytic Laminin Maintains Blood-Brain Barrier Integrity in an Age-Dependent MannerJyoti Gautam, Yu Cao, Yao Yao · 2019 · Translational Stroke Research
- Exploring the microbiota-gut-brain axis: impact on brain structure and functionLidya K. Yassin, Mohammed Moutaz Nakhal, Alreem Alderei, Afra Almehairbi, Ayishal B. Mydeen, Amal A. Akour, Mohammad I. K. Hamad · 2025 · Frontiers in Neuroanatomy
- Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammationÇiğdem Acıoğlu, Stella Elkabes · 2025 · Journal of Neuroinflammation
- Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s DiseaseRobert Powers, Shulei Lei, Annadurai Anandhan, Darrell D. Marshall, Bradley Worley, Ronald L. Cerny, Eric D. Dodds, Yuting Huang, Mihalis I. Panayiotidis, Aglaia Pappa et al. · 2017 · Metabolites
- Sleep and circadian rhythm disruption and stress intersect in Alzheimer's diseaseTrongha Phan, Roneil Gopal Malkani · 2018 · Neurobiology of Stress
- [Metabolic difference between visceral fat and subcutaneous abdominal fat].Per A Björntorp · 2000 · PubMed
- State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future DirectionsKaleen M. Lavin, Paul M. Coen, Liliana Carina Pereira Baptista, Margaret B. Bell, Devin J. Drummer, Sara A. Harper, Manoel E. Lixandrão, Jeremy S. McAdam, Samia M. O’Bryan, Sofhia Verena Ramos et al. · 2022 · Comprehensive physiology
- Cancer Chemotherapy Related Cognitive Impairment and the Impact of the Alzheimer’s Disease Risk Factor APOEHarvey R. Fernandez, Ashima Varma, Sarah A. Flowers, George William Rebeck · 2020 · Cancers
- Sex differences in stroke outcome correspond to rapid and severe changes in gut permeability in adult Sprague-Dawley ratsYumna El-Hakim, Kathiresh Kumar Mani, Amir Eldouh, Sivani Pandey, Maria T. Grimaldo, Alan R. Dabney, Rachel Pilla, Farida Sohrabji · 2021 · Biology of Sex Differences
- Why is delirium more frequent in the elderly?Orso Bugiani · 2021 · Neurological Sciences
- A Leaky Blood–Brain Barrier to Fibrinogen Contributes to Oxidative Damage in Alzheimer’s DiseaseJames G. McLarnon · 2021 · Antioxidants
- Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture MethodsHyun-Jung Yoo, Min‐Soo Kwon · 2022 · Frontiers in Aging Neuroscience
- Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine CCL24 in Peripheral Blood Mononuclear Cells from Elderly PeopleYoshinori Katakura, Mamoru Totsuka, Etsuko Imabayashi, Hiroshi Matsuda, Tatsuhiro Hisatsune · 2017 · Nutrients
- Inhibition of Connexin43 hemichannels with Gap19 protects cerebral ischemia/reperfusion injury via the JAK2/STAT3 pathway in miceBeilei Chen, Yang Liu, Jian Chen, Yingzhu Chen, Lingling Zhang, Liangzhu Wang, Xiaobo Li, Yuping Li, Hailong Yu · 2018 · Brain Research Bulletin
- Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma marginsXihui Gao, Qi Yue, Yikang Liu, Dandan Fan, Kun Fan, Sihan Li, Jun Qian, Limei Han, Fang Fang, Fulin Xu et al. · 2018 · Theranostics
- The Active Role of Pericytes During Neuroinflammation in the Adult BrainFernanda Medina‐Flores, Gabriela Hurtado‐Alvarado, Mária A. Deli, Beatriz Gómez‐González · 2022 · Cellular and Molecular Neurobiology
- A New Hypothesis for Alzheimer’s Disease: The Lipid Invasion ModelRudge, Jonathan D’Arcy · 2022 · Journal of Alzheimer's Disease Reports
- Remodeling of the Neurovascular Unit Following Cerebral Ischemia and HemorrhageYoshimichi Satō, Jaime Falcone-Juengert, Teiji Tominaga, Hua Su, Jialing Liu · 2022 · Cells
- Association between Alzheimer’s Disease and Oral and Gut Microbiota: Are Pore Forming Proteins the Missing Link?Sebastian D Aguayo, Christina Maria Anna Pia Schuh, Benjamín Vicente, Luis Gerardo Aguayo · 2018 · Journal of Alzheimer s Disease
- Don't forget astrocytes when targeting Alzheimer's diseaseJessica S. Sadick, Shane Antony Liddelow · 2019 · British Journal of Pharmacology
- New Insights into the Role of Epithelial–Mesenchymal Transition during AgingFrancisco Denis Souza Santos, Cristiana Moreira, Sandrina Nóbrega Pereira, Bruno Bernardes de Jesus · 2019 · International Journal of Molecular Sciences
- Exercise prevents obesity-induced cognitive decline and white matter damage in miceLeah C. Graham, Weronika A. Grabowska, Yoona Chun, Shannon L. Risacher, Vivek M. Philip, Andrew J. Saykin, Stacey J. Sukoff Rizzo, Gareth R. Howell · 2019 · Neurobiology of Aging
- Potential effects of antibiotic‐induced gut microbiome alteration on blood–brain barrier permeability compromise in rhesus monkeysQiong Wu, Yingqian Zhang, Yinbing Zhang, Chunchao Xia, Qi Lai, Zaiquan Dong, Weihong Kuang, Cheng Yang, Dan Su, Hongxia Li et al. · 2020 · Annals of the New York Academy of Sciences
- Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairmentMan Li, Yue Li, Long Zuo, Wenli Hu, Tao Jiang · 2021 · BMC Neurology
- Microbiota-gut-brain axis and Alzheimer’s disease: Implications of the blood-brain barrier as an intervention targetShan Liu, Jiguo Gao, Kangding Liu, Hongliang Zhang · 2021 · Mechanisms of Ageing and Development
- Imaging subtle leaks in the blood–brain barrier in the aging human brain: potential pitfalls, challenges, and possible solutionsAxel Montagne, Samuel R. Barnes, Daniel A. Nation, Kassandra Kisler, Arthur W. Toga, Berislav V. Zloković · 2022 · GeroScience
- How does neurovascular unit dysfunction contribute to multiple sclerosis?Jake M. Cashion, Kaylene M. Young, Brad A. Sutherland · 2023 · Neurobiology of Disease
- The physio-affective phenome of major depression is strongly associated with biomarkers of astroglial and neuronal projection toxicity which in turn are associated with peripheral inflammation, insulin resistance and lowered calciumHussein Kadhem Al‐Hakeim, Tabarek Hadi Al-Naqeeb, Abbas Firras Almulla, Michael H. J. Maes · 2023 · Journal of Affective Disorders
- Mitochondria in brain diseases: Bridging structural-mechanistic insights into precision-targeted therapiesJun Liao, Wenxiu He, Lisha Li, Jingya Wang, Lidong Gong, Qiang Zhang, Zhiqiang Lin · 2025 · Cell Biomaterials
- Cognitive impairment after traumatic brain injury: The role of MRI and possible pathological basisMing-Liang Wang, Wenbin Li · 2016 · Journal of the Neurological Sciences
- Electrocorticographic Dynamics as a Novel Biomarker in Five Models of EpileptogenesisDan Z. Milikovsky, Itai Weissberg, Lyna Kamintsky, Kristina Lippmann, Osnat Schefenbauer, Federica Frigerio, Massimo Rizzi, Liron Sheintuch, Daniel Zelig, Jonathan Ofer et al. · 2017 · Journal of Neuroscience
- Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functionsXing Zhang, Xiaorui Han, Ke Xia, Yongmei Xu, Yimu Yang, Kaori Oshima, Sarah M. Haeger, Mario J. Perez, Sarah A. McMurtry, Joseph A. Hippensteel et al. · 2019 · Proceedings of the National Academy of Sciences
- Glio-vascular changes during ageing in wild-type and Alzheimer׳s disease-like APP/PS1 miceCátia S. Janota, Dora Maria Tuna Oliveira Brites, Cynthia Ann Lemere, María Alexandra Brito · 2015 · Brain Research
- Headaches and Magnesium: Mechanisms, Bioavailability, Therapeutic Efficacy and Potential Advantage of Magnesium PidolateJeanette A.M. Maier, Gisele P Pickering, Elena Giacomoni, Alessandra Cazzaniga, Paolo Pellegrino · 2020 · Nutrients
- An emerging role of astrocytes in aging/neuroinflammation and gut-brain axis with consequences on sleep and sleep disordersSergey V. Gudkov, Dmitriy E. Burmistrov, Elena V. Kondakova, Ruslan M. Sarimov, Roman S. Yarkov, Claudio Franceschi, Maria V. Vedunova · 2022 · Ageing Research Reviews
- Targeting the blood–brain barrier to delay aging-accompanied neurological diseases by modulating gut microbiota, circadian rhythms, and their interplaysYanping Wang, Weihong Du, Xiaoyan Hu, Xin Yu, Chun Guo, Xinchun Jin, Wei Wang · 2023 · Acta Pharmaceutica Sinica B
- Endothelial Cell Senescence Effect on the Blood-Brain Barrier in Stroke and Cognitive ImpairmentMaria Guadalupe C. Real, Sarina R. Falcione, Roobina Boghozian, Michael Clarke, Raluca Todoran, Alexis St Pierre, Yiran Zhang, Twinkle Joy, Glen C. Jickling · 2024 · Neurology
- Re-engineering therapeutic antibodies for Alzheimer’s disease as blood-brain barrier penetrating bi-specific antibodiesWilliam M. Pardridge · 2016 · Expert Opinion on Biological Therapy
- Aging Exacerbates Neuroinflammatory Outcomes Induced by Acute Ozone ExposureChristina R. Steadman, Shahani Noor, Tamara L. Young, Valeria Rivero, Bethany Sanchez, Selitá Lucas, Kevin K. Caldwell, Erin D. Milligan, Matthew J. Campen · 2018 · Toxicological Sciences
- Genetic Approaches Using Zebrafish to Study the Microbiota–Gut–Brain Axis in Neurological DisordersJae Geun Lee, Hyun-Ju Cho, Yun-Mi Jeong, Jeong-Soo Lee · 2021 · Cells
- Quantitative Relationship Between Cerebrovascular Network and Neuronal Cell Types in MiceYuan-Ting Wu, Hannah C. Bennett, Uree Chon, Daniel J. Vanselow, Qingguang Zhang, Rodrigo Muñoz-Castañeda, Keith C. Cheng, Pavel Osten, Patrick J. Drew, Yongsoo Kim · 2022 · Cell Reports
- Astrocytes in agingLara Labarta-Bajo, Nicola J. Allen · 2025 · Neuron
- The effect of aging on brain barriers and the consequences for Alzheimer’s disease developmentNina Gorlé, Caroline Van Cauwenberghe, Claude Libert, Roosmarijn E. Vandenbroucke · 2016 · Mammalian Genome
- Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer’s diseasePatricia Kelly, Paul Denver, Simon C. Satchell, Maximilian Ackermann, Moritz Anton Konerding, Christopher A. Mitchell · 2017 · Angiogenesis
- Role of pattern recognition receptors of the neurovascular unit in inflamm-agingWilhelm, Imola, Nyúl-Tóth, Ádám, Kozma, Mihály, Farkas, Attila E., Krizbai, István A. · 2017 · American Journal of Physiology-Heart and Circulatory Physiology
- Precision Aging: Applying Precision Medicine to the Field of Cognitive AgingLee Ryan, Meredith Hay, Matthew J. Huentelman, Audrey Duarte, Tatjana Rundek, Bonnie E. Levin, Anja Soldan, Corinne A. Pettigrew, Matthias R. Mehl, Carol Ann Barnes · 2019 · Frontiers in Aging Neuroscience
- Herpes simplex virus type 1 and Alzheimer’s disease: link and potential impact on treatmentRoberta Mancuso, Mariaconcetta Sicurella, Simone Agostini, Peggy Marconi, Mario Clerici · 2019 · Expert Review of Anti-infective Therapy
- The Role of Natural Antioxidants in the Prevention of Dementia—Where Do We Stand and Future PerspectivesAnamaria Jurcău · 2021 · Nutrients
- The role of extracellular matrix alterations in mediating astrocyte damage and pericyte dysfunction in Alzheimer's disease: A comprehensive reviewMai M. Anwar, Esra Özkan, Yasemin Özdemir · 2021 · European Journal of Neuroscience
- Inflammation: major denominator of obesity, Type 2 diabetes and Alzheimer’s disease-like pathology?Miroslava Kacířová, Anna Zmeškalová, Lucia Kořínková, Blanka Železná, Jaroslav Kuneš, Lenka Maletı́nská · 2020 · Clinical Science
- Blood–Brain Barrier Disruption and Perivascular Spaces in Small Vessel Disease and Neurodegenerative Diseases: A Review on MRI Methods and InsightsPaulien Voorter, Maud van Dinther, Willemijn J. Jansen, Alida Annechien Postma, Julie Staals, Jacobus F.A. Jansen, Robert J. van Oostenbrugge, Merel M. van der Thiel, Walter H. Backes · 2023 · Journal of Magnetic Resonance Imaging
- Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and bloodMatthias J.P. van Osch, Anders Wåhlin, Paul Scheyhing, Ingrid Mossige, Lydiane Hirschler, Anders Eklund, Klara Mogensen, Ryszard S. Gomolka, Alexander Radbruch, Sara Qvarlander et al. · 2024 · NMR in Biomedicine
- Synaptic plasticity modulation by circulating peptides and metaplasticity: Involvement in Alzheimer’s diseaseStéphane Peineau, Kevin Rabiant, Olivier Pierrefiche, Brigitte Potier · 2018 · Pharmacological Research
- Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathwayMengmeng You, Zhuoning Miao, Yongming Pan, Fuliang Hu · 2019 · European Journal of Pharmacology
- Links between Immune Cells from the Periphery and the Brain in the Pathogenesis of Epilepsy: A Narrative ReviewGaku Yamanaka, Shinichiro Morıchı, Tomoko Takamatsu, Yusuke Watanabe, Shinji Suzuki, Yu Ishida, Shingo Oana, Takashi Yamazaki, Fuyuko Takata, Hisashi Kawashima · 2021 · International Journal of Molecular Sciences
- Blood-Based Biomarkers of Neuroinflammation in Alzheimer’s Disease: A Central Role for Periphery?Federica Angiulli, Elisa Conti, C Zoia, Fulvio Da Re, Ildebrando Marco Appollonio, Carlo Ferrarese, Lucio Tremolizzo · 2021 · Diagnostics
- The Applications of Focused Ultrasound (FUS) in Alzheimer’s Disease Treatment: A Systematic Review on Both Animal and Human StudiesXiaodan Liu, S Sta Maria Naomi, Wu Lin Sharon, E. Jacobs Russell · 2021 · Aging and Disease
- Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier LevelSweilem B. Al Rihani, Lucy I. Darakjian, Malavika Deodhar, Pamela Dow, Jacques Turgeon, Véronique Michaud · 2021 · International Journal of Molecular Sciences
- Prenatal disruption of blood–brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammationZhao, Qiuying, Dai, Weiye, Chen, Hui Yu, Jacobs, Russell E., Zlokovic, Berislav V., Lund, Brett T., Montagne, Axel, Bonnin, Alexandre · 2022 · Proceedings of the National Academy of Sciences
- Quantitative Water Permeability Mapping of Blood-Brain-Barrier Dysfunction in AgingJeremy N. Ford, Qihao Zhang, Elizabeth M. Sweeney, Alexander Eliot Merkler, Mony J. de Leon, Ajay Kumar Gupta, Thanh Duc Nguyen, Jana Ivanidze · 2022 · Frontiers in Aging Neuroscience
- Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s diseaseJames Scott Miners, Carol Van Hulle, Selvi Ince, Erin Jonaitis, OC Okonkwo, Barbara B. Bendlin, Sterling C. Johnson, Cynthia M. Carlsson, Sanjay Asthana, Seth Love et al. · 2024 · Translational Psychiatry
- Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluidAleksandra Wojtas, Eric B. Dammer, Qi Guo, Lingyan Ping, Anantharaman Shantaraman, Duc M. Duong, Luming Yin, Edward J. Fox, Fatemeh Seifar, Edward B. Lee et al. · 2024 · Alzheimer s & Dementia
- Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented ElderlySarah Westwood, Emanuela Leoni, Abdul Hye, Steven Lynham, Mizanur R. Khondoker, Nicholas James Ashton, Steven John Kiddle, Alison L. Baird, Ricardo Sáinz‐Fuertes, Rufina Leung et al. · 2016 · Journal of Alzheimer s Disease
- Heart Failure and Cognitive Impairment: Clinical Relevance and Therapeutic ConsiderationsTuoyo Omasan Mene-Afejuku, Monica Pernia, Uzoma N. Ibebuogu, Shobhana Chaudhari, Savi Mushiyev, Ferdinand Visco, Gerald Pekler · 2019 · Current Cardiology Reviews
- Human iPSC‐Derived Blood‐Brain Barrier Models: Valuable Tools for Preclinical Drug Discovery and Development?Antje Appelt‐Menzel, Sabrina Oerter, Sanjana Mathew, Undine Haferkamp, Carla Hartmann, Matthias Jung, Winfried Neuhaus, Ole Pleß · 2020 · Current Protocols in Stem Cell Biology
- Designing peptide nanoparticles for efficient brain deliveryAroa Duro‐Castaño, Diana M. Leite, Joe Forth, Yangwei Deng, Diana Matias, Carlos Noble-Jesus, Giuseppe Battaglia · 2020 · Advanced Drug Delivery Reviews
- A human brain vascular atlas reveals diverse cell mediators of Alzheimer’s disease riskYang, Andrew C., Vest, Ryan T., Kern, Fabian, Lee, Davis P., Maat, Christina A., Losada, Patricia M., Chen, Michelle B., Agam, Maayan, Schaum, Nicholas, Khoury, Nathalie et al. · 2021
- Aging impairs the essential contributions of non‐glial progenitors to neurorepair in the dorsal telencephalon of the Killifish Nothobranchius furzeriJolien Van houcke, Valerie Mariën, Caroline Zandecki, Sophie Vanhunsel, Lieve Moons, Rajagopal Ayana, Eve Seuntjens, Lut Arckens · 2021 · Aging Cell
- Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic ChangesClaudia Cicognola, Niklas Mattsson, Danielle van Westen, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Khazar Ahmadi, Olof T. Strandberg, Erik Stomrud, Shorena Janelidze et al. · 2023 · Neurology
- Disordered APP metabolism and neurovasculature in trauma and aging: Combined risks for chronic neurodegenerative disordersMiloš D. Ikonomović, Zhiping Mi, Eric E. Abrahamson · 2016 · Ageing Research Reviews
- High‐fat diet protects the blood–brain barrier in an Alzheimer's disease mouse modelShirin Elhaik Goldman, David Goez, David Last, Sharone Naor, Sigal Liraz Zaltsman, Inbal Sharvit‐Ginon, Dana Atrakchi, Chen Shemesh, Rachel Twitto‐Greenberg, Shoval Tsach et al. · 2018 · Aging Cell
- Neurovascular Ageing and Age-Related DiseasesRaj N. Kalaria, Yoshiki Hase · 2019 · Sub-cellular biochemistry/Subcellular biochemistry
- Advances in the development paradigm of biosample‐based biosensors for early ultrasensitive detection of alzheimer’s diseaseHem Prakash Karki, Yeongseok Jang, Jinmu Jung, Jonghyun Oh · 2021 · Journal of Nanobiotechnology
- Physiological and Pathological Factors Affecting Drug Delivery to the Brain by NanoparticlesYamir Islam, Andrew G. Leach, Jayden A. Smith, Stefano Pluchino, Christopher R. Coxon, Muttuswamy Sivakumaran, James R. Downing, Amos A. Fatokun, Meritxell Teixidò, Touraj Ehtezazi · 2021 · Advanced Science
- TNF‐α antagonism rescues the effect of ageing on stroke: Perspectives for targeting inflamm‐ageingLuca Liberale, Nicole R. Bonetti, Yustina M. Puspitasari, Ana Vukolic, Alexander T. Akhmedov, Candela Díaz-Cañestro, Stephan Sylvest Keller, Fabrizio Montecucco, Mario Merlini, Aurora Semerano et al. · 2021 · European Journal of Clinical Investigation
- Endothelial dysfunctions in blood-brain barrier breakdown in alzheimer's disease: from mechanisms to potential therapiesYue, Qian, Leng, Xinyue, Xie, Ningqing, Zhang, Zaijun, Yang, Deguang, Hoi, Maggie Pui Man · 2024 · CNS Neuroscience & Therapeutics
- Location Matters: Navigating Regional Heterogeneity of the Neurovascular UnitLouis‐Philippe Bernier, Clément Brunner, Azzurra Cottarelli, Matilde Balbi · 2021 · Frontiers in Cellular Neuroscience
- Manual acupuncture benignly regulates blood-brain barrier disruption and reduces lipopolysaccharide loading and systemic inflammation, possibly by adjusting the gut microbiotaYue Zhang, Ning Ding, Xin Hao, Jun Zhao, Yali Zhao, Yiran Li, Zhigang Li · 2022 · Frontiers in Aging Neuroscience
- Neurodegenerative disease of the brain: a survey of interdisciplinary approachesFranca Davenport, John Gallacher, Zoe Kourtzi, Ivan G. Koychev, Paul McMahan Matthews, Neil P. Oxtoby, Laura M. Parkes, Viola Priesemann, James Benedict Rowe, S W Smye et al. · 2023 · Journal of The Royal Society Interface
- Roles of the Receptor for Advanced Glycation End Products and Its Ligands in the Pathogenesis of Alzheimer’s DiseaseWen Li, Qiuping Chen, Cheng Peng, Dan Yang, Si Liu, Yanwen Lv, Langqi Jiang, Shi‐Jun Xu, Huang Li-hua · 2025 · International Journal of Molecular Sciences
- The Alzheimer's disease risk factor CD2AP maintains blood–brain barrier integrityJ. Nicholas Cochran, Travis Rush, Susan C. Buckingham, Erik D. Roberson · 2015 · Human Molecular Genetics
- Novel method to study pericyte contractility and responses to ischaemia in vitro using electrical impedanceAin A. Neuhaus, Yvonne Couch, Brad A. Sutherland, Alastair Mitchell Buchan · 2016 · Journal of Cerebral Blood Flow & Metabolism
- TMEM16A Inhibition Preserves Blood–Brain Barrier Integrity After Ischemic StrokePinyi Liu, Zhi Zhang, Yi Liu, Xuelian Tang, Shu Shu, Xinyu Bao, Yan Zhang, Yue Gu, Yun Xu, Xiang Cao · 2019 · Frontiers in Cellular Neuroscience
- Multicenter Alzheimer's and Parkinson's disease immune biomarker verification studyBrosseron, Frederic, Kolbe, Carl‐Christian, Santarelli, Francesco, Carvalho, Stephanie, Antonell, Anna, Castro‐Gomez, Sergio, Tacik, Pawel, Namasivayam, Aishwarya Alex, Mangone, Graziella, Schneider, Reinhard et al. · 2020 · Alzheimer's & Dementia
- The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut FeelingCarolina Pereira Osorio, Tulasi Kanukuntla, Eddie Lee Diaz, Nyla Jafri, Michael Cummings, Adonis Sfera · 2019 · Frontiers in Aging Neuroscience
- Blood-brain barrier integrity is the primary target of alcohol abuseJiangping Wei, Yuan Dai, Wen Wen, Jin Li, Lingyu Linda Ye, Shijun Xu, Dayue Darrel Duan · 2021 · Chemico-Biological Interactions