The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Endolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice
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Lysosome impairment is among the earliest pathological events that affect MNs in G93A mice.
“Remarkably, lysosome impairment is among the earliest pathological events that affect MNs in G93A mice7.”
From Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis (2020) · cites this paper as [7]
Lysosomal deficits are well documented in G93A mice, and starting from day 40, CTSD levels are significantly reduced in motor neurons from these mice.
“Lysosomal deficits are well documented in G93A mice and starting from day 40, the levels of CTSD are significantly reduced in MNs7 from these mice.”
From Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis (2020) · cites this paper as [7]
By applying both immuno-TEM and Airyscan confocal imaging, it is possible to obtain a comprehensive and quantitative analysis of LAMP1 distribution in various autophagic organelles in neurons.
“By applying both immuno-TEM and Airyscan confocal imaging, it is possible to obtain a comprehensive and quantitative analysis of LAMP1 distribution in various autophagic organelles in neurons [188,189].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [189]
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1 retracted
Foust, K. D., Wang, X., McGovern, V. L., Braun, L., Bevan, A. K., Haidet, A. M., Le, T. T., Morales, P. R., Rich, M. M., Burghes, A. H. M., et al. (2010) · Nature Biotechnology · doi:10.1038/nbt.1610 · Cited by 688
Self-citationRetractedRosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H.-X., et al. (1993) · Nature · doi:10.1038/362059a0 · Cited by 7,062
Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
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Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
Maday, S., Wallace, K. E., & Holzbaur, E. L. F. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201106120 · Cited by 681 · cited 1×
“Since neurons are particularly sensitive to the accumulation of misfolded proteins and damaged organelles, newly formed autophagosomes are eliminated quickly by fusing with endolysosomes, thereby avoiding a buildup of AVs (Maday et al., 2012; Cheng et al., 2015).”
BackgroundLithium delays progression of amyotrophic lateral sclerosis
Fornai, F., Longone, P., Cafaro, L., Kastsiuchenka, O., Ferrucci, M., Manca, M. L., Lazzeri, G., Spalloni, A., Bellio, N., Lenzi, P., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708022105 · Cited by 550
Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial
Chiò, A., Borghero, G., Calvo, A., Capasso, M., Caponnetto, C., Corbo, M., Giannini, F., Logroscino, G., Mandrioli, J., Marcello, N., et al. (2010) · Neurology · doi:10.1212/wnl.0b013e3181ed9e7c · Cited by 96 · cited 1×
“Clinical trials by administering therapeutic doses of lithium showed no effect in ALS patients (Chiò et al., 2010).”
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Sorted by citations
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
Self-citationCompartment-Specific Regulation of Autophagy in Primary Neurons
Maday, S., & Holzbaur, E. L. F. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.4401-15.2016 · Cited by 309
Distinct roles for motor neuron autophagy early and late in the SOD1 G93A mouse model of ALS
Rudnick, N. D., Griffey, C. J., Guarnieri, P., Gerbino, V., Wang, X., Piersaint, J. A., Tapia, J. C., Rich, M. M., & Maniatis, T. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704294114 · Cited by 189
Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice
Rogers, R. S., Tungtur, S., Tanaka, T., Nadeau, L. L., Badawi, Y., Wang, H., Ni, H.-M., Ding, W.-X., & Nishimune, H. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00473 · Cited by 83
“In SOD1G93A mice, an ALS animal model, a defect of autophagosome fusion with lysosomes has been reported in the motor neuron cell body (Xie et al., 2015).”
BackgroundRetromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
Muzio, L., Sirtori, R., Gornati, D., Eleuteri, S., Fossaghi, A., Brancaccio, D., Manzoni, L., Ottoboni, L., Feo, L. D., Quattrini, A., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-17524-7 · Cited by 65
Molecular mechanisms of mitophagy and its roles in neurodegenerative diseases
Li, X., Huang, L., Lan, J., Feng, X., Li, P., Wu, L., & Peng, Y. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2020.105240 · Cited by 57
Natale, G., Lenzi, P., Lazzeri, G., Falleni, A., Biagioni, F., Ryskalin, L., & Fornai, F. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00434 · Cited by 42
Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes
Moruno-Manchon, J. F., Uzor, N.-E., Ambati, C. R., Shetty, V., Putluri, N., Jagannath, C., McCullough, L. D., & Tsvetkov, A. S. (2018) · Cell Death & Disease · doi:10.1038/s41419-018-0599-5 · Cited by 36
Metadata
- Authors
- Xie, Y., Zhou, B., Lin, M.-Y., Wang, S., Foust, K. D., & Sheng, Z.-H.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 87
- Issue
- 2
- Pages
- 355-370
- ISSN
- 0896-6273
- PMC
- PMC4511489
- Cited by
- 149
- References
- 6
- Language
- en
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