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Targeting Inflammatory-Mitochondrial Response in Major Depression: Current Evidence and Further Challenges

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Imipramine Induces Brain-Derived Neurotrophic Factor mRNA Expression in Cultured Astrocytes

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Imipramine and fluoxetine inhibit LPS-induced activation and affect morphology of microglial cells in the rat glial culture

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Exposure to Antidepressant Medication and the Risk of Incident Dementia

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Inhibition of Inflammation Mediated Through the Tumor Necrosis Factor α Biochemical Pathway Can Lead to Favorable Outcomes in Alzheimer Disease

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Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: Reversibility by imipramine and pentoxifylline

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Chemocentric Informatics Approach to Drug Discovery: Identification and Experimental Validation of Selective Estrogen Receptor Modulators as Ligands of 5-Hydroxytryptamine-6 Receptors and as Potential Cognition Enhancers

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Imipramine and amitriptyline ameliorate the rotenone model of Parkinson’s disease in rats

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The Monoaminergic Tripartite Synapse: A Putative Target for Currently Available Antidepressant Drugs

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HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads

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Microglia under psychosocial stressors along the aging trajectory: Consequences on neuronal circuits, behavior, and brain diseases

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Bioenergetics and synaptic plasticity as potential targets for individualizing treatment for depression

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The effect of different antidepressant drugs of oxidative stress after lipopolysaccharide administration in mice

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Natural Flavone Jaceosidin is a Neuroinflammation Inhibitor

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Behavioral defects induced by chronic social defeat stress are protected by Momordica charantia polysaccharides via attenuation of JNK3/PI3K/AKT neuroinflammatory pathway

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Moclobemide exerts anti-inflammatory effect in lipopolysaccharide-activated primary mixed glial cell culture

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Curcumin as a putative antidepressant

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Mangiferin inhibits hippocampal NLRP3 inflammasome and exerts antidepressant effects in a chronic mild stress mice model

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Pathologic role of nitrergic neurotransmission in mood disorders

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Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes

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Sub-chronic agmatine treatment modulates hippocampal neuroplasticity and cell survival signaling pathways in mice

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Potentiation of Amitriptyline Anti-Hyperalgesic-Like Action By Astroglial Connexin 43 Inhibition in Neuropathic Rats

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Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes

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How Does COVID-19 Affect the Neurobiology of Suicide?

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The fiery landscape of depression: A review of the inflammatory hypothesis

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Plasma complement component 4 increases in patients with major depressive disorder

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Antitumoral Effects of Tricyclic Antidepressants: Beyond Neuropathic Pain Treatment

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The Anti-inflammatory Effect of the Tricyclic Antidepressant Clomipramine and Its High Penetration in the Brain Might Be Useful to Prevent the Psychiatric Consequences of SARS-CoV-2 Infection

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Effects of psychotropic drugs on Nuclear Factor kappa B.

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Imipramine impedes glioma progression by inhibiting YAP as a Hippo pathway independent manner and synergizes with temozolomide

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Antidepressants inhibit proton currents and tumor necrosis factor-α production in BV2 microglial cells

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NF-κΒ Signaling in Neurite Growth and Neuronal Survival

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Somatic Drugs for Psychiatric Diseases: Aspirin or Simvastatin for Depression?

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Suppressive immunoregulatory effects of three antidepressants via inhibition of the nuclear factor-κB activation assessed using primary macrophages of carp ( Cyprinus carpio )

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Selective serotonin reuptake inhibitors and inflammatory bowel disease; Beneficial or malpractice

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Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-α and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats

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Dopaminergic impact of cART and anti-depressants on HIV neuropathogenesis in older adults

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Repurposing psychiatric medicines to target activated microglia in anxious mild cognitive impairment and early Parkinson's disease.

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Imipramine enhances cell proliferation and decreases neurodegeneration in the hippocampus after transient global cerebral ischemia in rats

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Inhibition of TNF-α-induced neuronal apoptosis by antidepressants acting through the lysophosphatidic acid receptor LPA1

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Tricyclic Antidepressants Modulate Stressed Mitochondria in Glioblastoma Multiforme Cells

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What you eat is what you are – A role for polyunsaturated fatty acids in neuroinflammation induced depression?

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Antidepressant-like effects of Salvianolic acid B in the mouse forced swim and tail suspension tests

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Serotoninergic system targeting in multiple sclerosis: the prospective for pathogenetic therapy.

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The neurodegenerative hypothesis of depression and the influence of antidepressant medications

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Effect of tricyclic antidepressants on L-DOPA-induced dyskinesia and motor improvement in hemi-parkinsonian rats

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Antidepressants, β-Arrestins and GRKs: From Regulation of Signal Desensitization to Intracellular Multifunctional Adaptor Functions

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Off-Target Effects of Antidepressants on Vascular Function and Structure

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Celecoxib attenuates depressive-like behavior associated with immunological liver injury in C57BL/6 mice through TNF-α and NF-κb dependent mechanisms

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Inhibitory effect of the antidepressant imipramine on NF-κB-dependent CXCL1 expression in TNFα-exposed astrocytes.

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Imipramine and fluoxetine inhibit LPS-induced activation and affect morphology of microglial cells in the rat glial culture

Obuchowicz, E., Bielecka, A., Paul-Samojedny, M., Pudełko, A., & Kowalski, J. (2014) · Pharmacological Reports · doi:10.1016/j.pharep.2013.08.002 · Cited by 68 · see citing works

Trazodone exerts cytoprotective effects in human activated microglial cells by modulating inflammatory pathwaysPreprint

Chelucci, E., Daniele, S., Vergassola, M., Ceccarelli, L., Zucchi, S., Boltri, L., & Martini, C. (2024) · doi:10.22541/au.172449918.83105698/v1

The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production

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Trazodone counteracts the response of microglial cells to inflammatory stimuli

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