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Molecular Insights into Cell Type-specific Roles in Alzheimer’s Disease: Human Induced Pluripotent Stem Cell-based Disease Modelling

Qu, Wenhui, Canoll, Peter, Hargus, Gunnar·2023·Neuroscience

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  1. Abud, 2017, iPSC-derived human microglia-like cells to study neurological diseases, Neuron, 94, 278, 10.1016/j.neuron.2017.03.042 · DOI · Paper page
  2. Aisenbrey, 2021, A protocol for rapid pericyte differentiation of human induced pluripotent stem cells, STAR Protoc, 2, 100261, 10.1016/j.xpro.2020.100261 · DOI
  3. Bartzokis, 2007, Apolipoprotein E affects both myelin breakdown and cognition: implications for age-related trajectories of decline into dementia, Biol Psychiatry, 62, 1380, 10.1016/j.biopsych.2007.03.024 · DOI · Paper page
  4. Benilova, 2012, The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes, Nat Neurosci, 15, 349, 10.1038/nn.3028 · DOI · Paper page
  5. Bergström, 2016, Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation, Sci Rep, 6, 1, 10.1038/srep29200 · DOI
  6. Bernabeu-Zornoza, 2019, Physiological and pathological effects of amyloid-beta species in neural stem cell biology, Neural Regen Res, 14, 2035, 10.4103/1673-5374.262571 · DOI
  7. Bloom, 2014, Amyloid-beta and tau: the trigger and bullet in Alzheimer disease pathogenesis, JAMA Neurol, 71, 505, 10.1001/jamaneurol.2013.5847 · DOI
  8. Born, 2015, Seizures in Alzheimer's disease, Neuroscience, 286, 251, 10.1016/j.neuroscience.2014.11.051 · DOI
  9. Brownjohn, 2018, Functional studies of missense TREM2 mutations in human stem cell-derived microglia, Stem Cell Rep, 10, 1294, 10.1016/j.stemcr.2018.03.003 · DOI · Paper page
  10. Butt, 2019, Oligodendroglial Cells in Alzheimer's disease, Adv Exp Med Biol, 1175, 325, 10.1007/978-981-13-9913-8_12 · DOI
  11. Cakir, 2019, Engineering of human brain organoids with a functional vascular-like system, Nat Methods, 16, 1169, 10.1038/s41592-019-0586-5 · DOI
  12. Cenini, 2021, Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models, Mol Cell Neurosci, 110, 103568, 10.1016/j.mcn.2020.103568 · DOI
  13. Ceyzeriat, 2020, Learning from the past: A review of clinical trials targeting amyloid, tau and neuroinflammation in Alzheimer's disease, Curr Alzheimer Res, 17, 112, 10.2174/1567205017666200304085513 · DOI
  14. Chow, 2010, An overview of APP processing enzymes and products, Neuromolecular Med, 12, 1, 10.1007/s12017-009-8104-z · DOI · Paper page
  15. Csobonyeiova, 2019, Recent progress in the regeneration of spinal cord injuries by induced pluripotent stem cells, Int J Mol Sci, 20, 3838, 10.3390/ijms20153838 · DOI
  16. Das, 2017, Role of BACE1 in Alzheimer's synaptic function, Transl Neurodegener, 6, 23, 10.1186/s40035-017-0093-5 · DOI
  17. Daviaud, 2018, Vascularization and engraftment of transplanted human cerebral organoids in mouse cortex, eNeuro, 5, 10.1523/ENEURO.0219-18.2018 · DOI
  18. Delizannis, 2021, Effects of microglial depletion and TREM2 deficiency on Abeta plaque burden and neuritic plaque tau pathology in 5XFAD mice, Acta Neuropathol Commun, 9, 150, 10.1186/s40478-021-01251-1 · DOI
  19. Delpech, 2021, Wolframin-1-expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice, Sci Transl Med, 13, eabe8455, 10.1126/scitranslmed.abe8455 · DOI
  20. Delsing, 2020, Models of the blood-brain barrier using iPSC-derived cells, Mol Cell Neurosci, 107, 103533, 10.1016/j.mcn.2020.103533 · DOI
  21. dos Santos, 2017, Validating GWAS variants from microglial genes implicated in Alzheimer’s disease, J Mol Neurosci, 62, 215, 10.1007/s12031-017-0928-7 · DOI
  22. Douvaras, 2017, Directed differentiation of human pluripotent stem cells to microglia, Stem Cell Rep, 8, 1516, 10.1016/j.stemcr.2017.04.023 · DOI · Paper page
  23. Elsworthy, 2021, Amyloid-beta precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiation, Mol Cell Neurosci, 114, 103631, 10.1016/j.mcn.2021.103631 · DOI
  24. Espuny-Camacho, 2013, Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo, Neuron, 77, 440, 10.1016/j.neuron.2012.12.011 · DOI · Paper page
  25. Fattorelli, 2021, Stem-cell-derived human microglia transplanted into mouse brain to study human disease, Nat Protoc, 16, 1013, 10.1038/s41596-020-00447-4 · DOI
  26. Ferrer, 2019, Involvement of oligodendrocytes in Tau seeding and spreading in Tauopathies, Front Aging Neurosci, 11, 112, 10.3389/fnagi.2019.00112 · DOI
  27. Frost, 2017, The role of astrocytes in amyloid production and Alzheimer's disease, Open Biol, 7, 170228, 10.1098/rsob.170228 · DOI
  28. Fu, 2019, A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology, Nat Neurosci, 22, 47, 10.1038/s41593-018-0298-7 · DOI · Paper page
  29. Gabande-Rodriguez, 2020, Microglial phagocytosis in aging and Alzheimer's disease, J Neurosci Res, 98, 284, 10.1002/jnr.24419 · DOI · Paper page
  30. Ghatak, 2019, Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls, Elife, 8, e50333, 10.7554/eLife.50333 · DOI · Paper page
  31. Goate, 1991, Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease, Nature, 349, 704, 10.1038/349704a0 · DOI · Paper page
  32. Gratuze, 2021, Activated microglia mitigate Abeta-associated tau seeding and spreading, J Exp Med, 218, 10.1084/jem.20210542 · DOI · Paper page
  33. Guttikonda, 2021, Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease, Nat Neurosci, 24, 343, 10.1038/s41593-020-00796-z · DOI
  34. Haass, 2012, Trafficking and proteolytic processing of APP, Cold Spring Harbor Perspect Med, 2, 10.1101/cshperspect.a006270 · DOI · Paper page
  35. Hallmann, 2017, Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein, Sci Rep, 7, 42991, 10.1038/srep42991 · DOI
  36. Han, 2013, Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice, Cell Stem Cell, 12, 342, 10.1016/j.stem.2012.12.015 · DOI · Paper page
  37. Hardy, 1991, Amyloid deposition as the central event in the aetiology of Alzheimer's disease, Trends Pharmacol Sci, 12, 383, 10.1016/0165-6147(91)90609-V · DOI · Paper page
  38. Hasselmann, 2019, Development of a chimeric model to study and manipulate human microglia in vivo, Neuron, 103, e1010, 10.1016/j.neuron.2019.07.002 · DOI · Paper page
  39. Hernández, 2020, Differences between human and murine tau at the N-terminal end, Front Aging Neurosci, 12, 11, 10.3389/fnagi.2020.00011 · DOI
  40. Hu, 1998, Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release, Brain Res, 785, 195, 10.1016/S0006-8993(97)01318-8 · DOI · Paper page
  41. Hu, 2009, Differentiation of human oligodendrocytes from pluripotent stem cells, Nat Protoc, 4, 1614, 10.1038/nprot.2009.186 · DOI
  42. Iovino, 2015, Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations, Brain, 138, 3345, 10.1093/brain/awv222 · DOI · Paper page
  43. Jack, 2010, Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade, Lancet Neurol, 9, 119, 10.1016/S1474-4422(09)70299-6 · DOI · Paper page
  44. Jacobs, 2021, In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline, Sci Transl Med, 13, 10.1126/scitranslmed.abj2511 · DOI
  45. Jehuda, 2018, Genome editing in induced pluripotent stem cells using CRISPR/Cas9, Stem Cell Rev Rep, 14, 323, 10.1007/s12015-018-9811-3 · DOI
  46. Johnstone, 1999, A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced, J Neuroimmunol, 93, 182, 10.1016/S0165-5728(98)00226-4 · DOI
  47. Jones, 2017, Aberrant iPSC-derived human astrocytes in Alzheimer's disease, Cell Death Dis, 8, 10.1038/cddis.2017.89 · DOI · Paper page
  48. Kamboh, 2012, Genome-wide association study of Alzheimer's disease, Transl Psychiatry, 2, 10.1038/tp.2012.45 · DOI
  49. Kametani, 2018, Reconsideration of amyloid hypothesis and Tau hypothesis in Alzheimer's disease, Front Neurosci, 12, 25, 10.3389/fnins.2018.00025 · DOI · Paper page
  50. Karow, 2018, Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program, Nat Neurosci, 21, 932, 10.1038/s41593-018-0168-3 · DOI
  51. Kazim, 2017, Early-onset network hyperexcitability in presymptomatic Alzheimer’s disease transgenic mice is suppressed by passive immunization with anti-human APP/Aβ antibody and by mGluR5 blockade, Front Aging Neurosci, 9, 71, 10.3389/fnagi.2017.00071 · DOI · Paper page
  52. Keren-Shaul, 2017, A unique microglia type associated with restricting development of Alzheimer's disease, Cell, 169, 1276, 10.1016/j.cell.2017.05.018 · DOI · Paper page
  53. Klein, 2014, Altered neurotransmission in the lateral amygdala in aged human apoE4 targeted replacement mice, Neurobiol Aging, 35, 2046, 10.1016/j.neurobiolaging.2014.02.019 · DOI
  54. Koch, 2012, Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of gamma-secretase activity in endogenous amyloid-beta generation, Am J Pathol, 180, 2404, 10.1016/j.ajpath.2012.02.012 · DOI
  55. Konttinen, 2019, PSEN1DeltaE9, APPswe, and APOE4 confer disparate phenotypes in human iPSC-Derived microglia, Stem Cell Rep, 13, 669, 10.1016/j.stemcr.2019.08.004 · DOI · Paper page
  56. Konttinen, 2019, PPARbeta/delta-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1DeltaE9 astrocytes, Glia, 67, 146, 10.1002/glia.23534 · DOI
  57. Krasemann, 2017, The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases, Immunity, 47, 566, 10.1016/j.immuni.2017.08.008 · DOI · Paper page
  58. Kuhn, 2021, Human induced pluripotent stem cell models of frontotemporal dementia with Tau pathology, Front Cell Dev Biol, 9, 766773, 10.3389/fcell.2021.766773 · DOI
  59. Kumar, 2017, Specification and diversification of pericytes and smooth muscle cells from mesenchymoangioblasts, Cell reports, 19, 1902, 10.1016/j.celrep.2017.05.019 · DOI
  60. Lauterborn, 2021, Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer's disease, Nat Commun, 12, 2603, 10.1038/s41467-021-22742-8 · DOI
  61. Lee, 2020, The use of patient-derived induced pluripotent stem cells for Alzheimer's disease modeling, Prog Neurobiol, 192, 10.1016/j.pneurobio.2020.101804 · DOI
  62. Levy-Lahad, 1995, Candidate gene for the chromosome 1 familial Alzheimer's disease locus, Science, 269, 973, 10.1126/science.7638622 · DOI · Paper page
  63. Li, 2018, iPSC modeling of presenilin1 mutation in Alzheimer's disease with cerebellar ataxia, Exp Neurobiol, 27, 350, 10.5607/en.2018.27.5.350 · DOI
  64. Lian, 2016, Astrocyte-microglia cross talk through complement activation modulates amyloid pathology in mouse models of Alzheimer's disease, J Neurosci, 36, 577, 10.1523/JNEUROSCI.2117-15.2016 · DOI · Paper page
  65. Lines, 2020, Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells, Mol Cell Neurosci, 109, 10.1016/j.mcn.2020.103553 · DOI
  66. Linnerbauer, 2020, Astrocyte crosstalk in CNS inflammation, Neuron, 108, 608, 10.1016/j.neuron.2020.08.012 · DOI · Paper page
  67. Maloney, 2007, Important differences between human and mouse APOE gene promoters: limitation of mouse APOE model in studying Alzheimer's disease, J Neurochem, 103, 1237, 10.1111/j.1471-4159.2007.04831.x · DOI · Paper page
  68. Mancuso, 2019, Stem-cell-derived human microglia transplanted in mouse brain to study human disease, Nat Neurosci, 22, 2111, 10.1038/s41593-019-0525-x · DOI · Paper page
  69. Martin-Maestro, 2017, Mitophagy failure in fibroblasts and iPSC-derived neurons of Alzheimer's disease-associated presenilin 1 mutation, Front Mol Neurosci, 10, 291, 10.3389/fnmol.2017.00291 · DOI · Paper page
  70. Masters, 2012, Biochemistry of amyloid beta-protein and amyloid deposits in Alzheimer disease, Cold Spring Harbor Perspect Med, 2, 10.1101/cshperspect.a006262 · DOI
  71. Maté de Gérando, 2021, Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state, Brain, 144, 1167, 10.1093/brain/awab011 · DOI
  72. Mathys, 2019, Single-cell transcriptomic analysis of Alzheimer’s disease, Nature, 570, 332, 10.1038/s41586-019-1195-2 · DOI · Paper page
  73. Matsui, 2021, Vascularization of human brain organoids, Stem Cells, 39, 1017, 10.1002/stem.3368 · DOI
  74. McAlpine, 2021, Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease, Nature, 595, 701, 10.1038/s41586-021-03734-6 · DOI · Paper page
  75. Mietelska-Porowska, 2014, Tau protein modifications and interactions: their role in function and dysfunction, Int J Mol Sci, 15, 4671, 10.3390/ijms15034671 · DOI
  76. Muffat, 2016, Efficient derivation of microglia-like cells from human pluripotent stem cells, Nat Med, 22, 1358, 10.1038/nm.4189 · DOI · Paper page
  77. Müller, 2021, Neuronal hyperexcitability in APP SWE/PS1dE9 mouse models of Alzheimer’s disease, J Alzheimers Dis, 81, 855, 10.3233/JAD-201540 · DOI
  78. Muratore, 2014, The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons, Hum Mol Genet, 23, 3523, 10.1093/hmg/ddu064 · DOI · Paper page
  79. Najm, 2020, In vivo chimeric Alzheimer's disease modeling of apolipoprotein E4 toxicity in human neurons, Cell Rep, 32, 10.1016/j.celrep.2020.107962 · DOI · Paper page
  80. Narasimhan, 2020, Human tau pathology transmits glial tau aggregates in the absence of neuronal tau, J Exp Med, 217, 10.1084/jem.20190783 · DOI
  81. Ortiz-Virumbrales, 2017, CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 (N141I) neurons, Acta Neuropathol Commun, 5, 77, 10.1186/s40478-017-0475-z · DOI
  82. Ovchinnikov, 2018, The impact of APP on Alzheimer-like pathogenesis and gene expression in down syndrome iPSC-derived neurons, Stem Cell Rep, 11, 32, 10.1016/j.stemcr.2018.05.004 · DOI
  83. Pampuscenko, 2020, Extracellular tau induces microglial phagocytosis of living neurons in cell cultures, J Neurochem, 154, 316, 10.1111/jnc.14940 · DOI
  84. Pandya, 2017, Differentiation of human and murine induced pluripotent stem cells to microglia-like cells, Nat Neurosci, 20, 753, 10.1038/nn.4534 · DOI · Paper page
  85. Papaspyropoulos, 2020, Modeling and targeting Alzheimer's disease with organoids, Front Pharmacol, 11, 396, 10.3389/fphar.2020.00396 · DOI
  86. Park, 2016, Tau mis-splicing in the pathogenesis of neurodegenerative disorders, BMB Rep, 49, 405, 10.5483/BMBRep.2016.49.8.084 · DOI
  87. Pomeshchik, 2020, Human iPSC-derived hippocampal spheroids: an innovative tool for stratifying Alzheimer disease patient-specific cellular phenotypes and developing therapies, Stem Cell Rep, 15, 256, 10.1016/j.stemcr.2020.06.001 · DOI · Paper page
  88. Preman, 2021, Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques, Mol Neurodegener, 16, 10.1186/s13024-021-00487-8 · DOI
  89. Purhonen, 2020, A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice, Nat Commun, 11, 322, 10.1038/s41467-019-14201-2 · DOI
  90. Qu, 2020, Loss of TREM2 confers resilience to synaptic and cognitive impairment in aged mice, J Neurosci, 40, 9552, 10.1523/JNEUROSCI.2193-20.2020 · DOI
  91. Qu, 2021, Microglial TREM2 at the intersection of brain aging and Alzheimer's disease, Neuroscientist
  92. Reich, 2020, Alzheimer's risk gene TREM2 determines functional properties of new type of human iPSC-derived microglia, Front Immunol, 11
  93. Richetin, 2020, Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease, Nat Neurosci, 23, 1567, 10.1038/s41593-020-00728-x · DOI
  94. Selkoe, 2016, The amyloid hypothesis of Alzheimer's disease at 25 years, EMBO Mol Med, 8, 595, 10.15252/emmm.201606210 · DOI · Paper page
  95. Serio, 2013, Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy, Proc Natl Acad Sci U S A, 110, 4697, 10.1073/pnas.1300398110 · DOI · Paper page
  96. Serrano-Pozo, 2011, Neuropathological alterations in Alzheimer disease, Cold Spring Harbor Perspect Med, 1, 10.1101/cshperspect.a006189 · DOI · Paper page
  97. Shaw, 2009, Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects, Ann Neurol, 65, 403, 10.1002/ana.21610 · DOI · Paper page
  98. Shi, 2018, Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight, Nat Rev Immunol, 18, 759, 10.1038/s41577-018-0051-1 · DOI · Paper page
  99. Shi, 2012, Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses, Nat Neurosci, 15, 477, 10.1038/nn.3041 · DOI · Paper page
  100. Shi, 2019, Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model, J Exp Med, 216, 2546, 10.1084/jem.20190980 · DOI · Paper page
  101. Simons, 2015, Oligodendrocytes: myelination and axonal support, Cold Spring Harb Perspect Biol, 8
  102. Sposito, 2015, Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT, Hum Mol Genet, 24, 5260, 10.1093/hmg/ddv246 · DOI · Paper page
  103. Sproul, 2014, Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors, PLoS ONE, 9, 10.1371/journal.pone.0084547 · DOI · Paper page
  104. Stancu, 2014, Models of beta-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism, Mol Neurodegener, 9, 51, 10.1186/1750-1326-9-51 · DOI · Paper page
  105. Svoboda, 2019, Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain, Proc Natl Acad Sci U S A, 116, 25293, 10.1073/pnas.1913541116 · DOI
  106. Sweeney, 2018, Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders, Nat Rev Neurol, 14, 133, 10.1038/nrneurol.2017.188 · DOI · Paper page
  107. Tábuas-Pereira, 2020, Alzheimer’s disease genetics: Review of Novel Loci associated with disease, Curr Genet Med Rep, 8, 1, 10.1007/s40142-020-00182-y · DOI
  108. Takahashi, 2007, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131, 861, 10.1016/j.cell.2007.11.019 · DOI · Paper page
  109. Takata, 2017, Induced-pluripotent-stem-cell-derived primitive macrophages provide a platform for modeling tissue-resident macrophage differentiation and function, Immunity, 47, 183, 10.1016/j.immuni.2017.06.017 · DOI
  110. Tarawneh, 2012, The clinical problem of symptomatic Alzheimer disease and mild cognitive impairment, Cold Spring Harb Perspect Med, 2, 10.1101/cshperspect.a006148 · DOI
  111. Trabzuni, 2012, MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies, Hum Mol Genet, 21, 4094, 10.1093/hmg/dds238 · DOI · Paper page
  112. Varela, 2019, Excitatory-inhibitory imbalance in Alzheimer's disease and therapeutic significance, Neurobiol Dis, 127, 605, 10.1016/j.nbd.2019.04.010 · DOI
  113. Wezyk, 2018, Overactive BRCA1 affects presenilin 1 in induced pluripotent stem cell-derived neurons in Alzheimer's disease, J Alzheimers Dis, 62, 175, 10.3233/JAD-170830 · DOI
  114. Wisniewski, 1985, Occurrence of Alzheimer's neuropathology and dementia in Down syndrome, Ann Neurol, 17, 278, 10.1002/ana.410170310 · DOI · Paper page
  115. Wolfe, 2019, The role of APOE and TREM2 in Alzheimer′ s disease—current understanding and perspectives, Int J Mol Sci, 20, 81, 10.3390/ijms20010081 · DOI
  116. Wu, 2016, Neuronal activity enhances tau propagation and tau pathology in vivo, Nat Neurosci, 19, 1085, 10.1038/nn.4328 · DOI · Paper page
  117. Xu, 2020, Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain, Nat Commun, 11, 1577, 10.1038/s41467-020-15411-9 · DOI
  118. Xu, 2019, Pathological changes in Alzheimer’s disease analyzed using induced pluripotent stem cell-derived human microglia-like cells, J Alzheimers Dis, 67, 357, 10.3233/JAD-180722 · DOI · Paper page
  119. Yang, 2017, Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations, Oncotarget, 8, 7900, 10.18632/oncotarget.13776 · DOI
  120. Zhang, 2013, Rapid single-step induction of functional neurons from human pluripotent stem cells, Neuron, 78, 785, 10.1016/j.neuron.2013.05.029 · DOI · Paper page
  121. Zhang, 2014, A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons, Biomaterials, 35, 1420, 10.1016/j.biomaterials.2013.11.028 · DOI · Paper page
  122. Zhang, 2021, Vascularized organoids on a chip: strategies for engineering organoids with functional vasculature, Lab Chip, 21, 473, 10.1039/D0LC01186J · DOI
  123. Zhao, 2011, The contribution of activated astrocytes to Abeta production: implications for Alzheimer's disease pathogenesis, J Neuroinflammation, 8, 150, 10.1186/1742-2094-8-150 · DOI
  124. Zhao, 2017, APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes, Hum Mol Genet, 26, 2690, 10.1093/hmg/ddx155 · DOI · Paper page
  125. Zhao, 2020, APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids, Nat Commun, 11, 5540, 10.1038/s41467-020-19264-0 · DOI · Paper page
  126. Zhou, 2011, The roles of amyloid precursor protein (APP) in neurogenesis: Implications to pathogenesis and therapy of Alzheimer disease, Cell Adh Migr, 5, 280, 10.4161/cam.5.4.16986 · DOI
  127. Zhou, 2020, Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease, Nat Med, 26, 131, 10.1038/s41591-019-0695-9 · DOI · Paper page

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Metadata

Authors
Qu, W., Canoll, P., & Hargus, G.
Venue
Neuroscience
Publisher
Elsevier BV
Published
2023-05
Volume
518
Pages
10-26
ISSN
0306-4522
Cited by
24
References
62
Language
en

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