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Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation

Martín-Maestro, Patricia, Gargini, Ricardo, A. Sproul, Andrew, García, Esther, Antón, Luis C., Noggle, Scott, Arancio, Ottavio, Avila, Jesús, García-Escudero, Vega·2017·Frontiers in Molecular Neuroscience
DOI 10.3389/fnmol.2017.00291PMC PMC5603661
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Research works printed but not linked: 34

  1. Antonell, 2013, A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer’s disease, Neurobiol. Aging, 34, 1772, 10.1016/j.neurobiolaging.2012.12.026 · DOI
  2. Baxter, 2007, 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (β-site APP cleaving enzyme): use of structure based design to convert a micromolar hit into a nanomolar lead, J. Med. Chem., 50, 4261, 10.1021/jm0705408 · DOI
  3. Bjørkøy, 2005, p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death, J. Cell Biol., 171, 603, 10.1083/jcb.200507002 · DOI · Paper page
  4. Borchelt, 1996, Familial Alzheimer’s disease-linked presenilin 1 variants elevate Aβ1–42/1–40 ratio in vitro and in vivo, Neuron, 17, 1005, 10.1016/s0896-6273(00)80230-5 · DOI · Paper page
  5. Coffey, 2014, Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP, Neuroscience, 263, 111, 10.1016/j.neuroscience.2014.01.001 · DOI
  6. Cruts, 1998, Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease, Hum. Mol. Genet., 7, 43, 10.1093/hmg/7.1.43 · DOI
  7. Dagda, 2009, Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission, J. Biol. Chem., 284, 13843, 10.1074/jbc.M808515200 · DOI · Paper page
  8. Dinnage, 2012, Diversity of plant evolutionary lineages promotes arthropod diversity, Ecol. Lett., 15, 1308, 10.1111/j.1461-0248.2012.01854.x · DOI
  9. Dovey, 2001, Functional γ-secretase inhibitors reduce β-amyloid peptide levels in brain, J. Neurochem., 76, 173, 10.1046/j.1471-4159.2001.00012.x · DOI
  10. Fedorowicz, 2014, Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy, EMBO Rep., 15, 86, 10.1002/embr.201337294 · DOI
  11. Gegg, 2010, Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy, Hum. Mol. Genet., 19, 4861, 10.1093/hmg/ddq419 · DOI · Paper page
  12. Hansen, 2011, Following autophagy step by step, BMC Biol., 9, 39, 10.1186/1741-7007-9-39 · DOI
  13. Ikeda, 2000, The expression of presenilin 1 mRNA in skin fibroblasts and brains from sporadic Alzheimer’s disease, Dement. Geriatr. Cogn. Disord., 11, 245, 10.1159/000017246 · DOI
  14. Kuusisto, 2002, Early accumulation of p62 in neurofibrillary tangles in Alzheimer’s disease: possible role in tangle formation, Neuropathol. Appl. Neurobiol., 28, 228, 10.1046/j.1365-2990.2002.00394.x · DOI
  15. Kuusisto, 2001, Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells, Biochem. Biophys. Res. Commun., 280, 223, 10.1006/bbrc.2000.4107 · DOI · Paper page
  16. Lee, 2015, Presenilin 1 maintains lysosomal Ca2+ homeostasis via TRPML1 by regulating vATPase-mediated lysosome acidification, Cell Rep., 12, 1430, 10.1016/j.celrep.2015.07.050 · DOI · Paper page
  17. Lee, 1996, Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues, J. Neurosci., 16, 7513, 10.1523/JNEUROSCI.16-23-07513.1996 · DOI
  18. Lee, 2010, Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations, Cell, 141, 1146, 10.1016/j.cell.2010.05.008 · DOI · Paper page
  19. Lemasters, 2005, Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging, Rejuvenation Res., 8, 3, 10.1089/rej.2005.8.3 · DOI
  20. Martín-Maestro, 2016, PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer’s disease, Hum. Mol. Genet., 25, 792, 10.1093/hmg/ddv616 · DOI · Paper page
  21. Moreira, Autophagocytosis of mitochondria is prominent in Alzheimer disease, J. Neuropathol. Exp. Neurol., 66, 525, 10.1097/01.jnen.0000240476.73532.b0 · DOI
  22. Moreira, Increased autophagic degradation of mitochondria in Alzheimer disease, Autophagy, 3, 614, 10.4161/auto.4872 · DOI
  23. Prè, 2014, A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs), PLoS One, 9, e103418, 10.1371/journal.pone.0103418 · DOI
  24. Rubinsztein, 2009, In search of an “autophagomometer”, Autophagy, 5, 585, 10.4161/auto.5.5.8823 · DOI · Paper page
  25. Sardiello, 2009, A gene network regulating lysosomal biogenesis and function, Science, 325, 473, 10.1126/science.1174447 · DOI · Paper page
  26. Sauvat, 2015, Quantification of cellular viability by automated microscopy and flow cytometry, Oncotarget, 6, 9467, 10.18632/oncotarget.3266 · DOI
  27. Sproul, 2015, Being human: the role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer’s disease models, Mol. Aspects Med., 54, 10.1016/j.mam.2015.06.007 · DOI
  28. Sproul, 2014, Characterization and molecular profiling of PSEN1 familial Alzheimer’s disease iPSC-derived neural progenitors, PLoS One, 9, e84547, 10.1371/journal.pone.0084547 · DOI · Paper page
  29. Tanaka, 2010, Parkin-mediated selective mitochondrial autophagy, mitophagy: parkin purges damaged organelles from the vital mitochondrial network, FEBS Lett., 584, 1386, 10.1016/j.febslet.2010.02.060 · DOI
  30. Vives-Bauza, 2010, PINK1-dependent recruitment of Parkin to mitochondria in mitophagy, Proc. Natl. Acad. Sci. U S A, 107, 378, 10.1073/pnas.0911187107 · DOI · Paper page
  31. Wang, 2016, Synaptosomal mitochondrial dysfunction in 5xFAD mouse model of Alzheimer’s disease, PLoS One, 11, e0150441, 10.1371/journal.pone.0150441 · DOI
  32. Wolfe, 2013, Autophagy failure in Alzheimer’s disease and the role of defective lysosomal acidification, Eur. J. Neurosci., 37, 1949, 10.1111/ejn.12169 · DOI
  33. Yamano, 2016, The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation, EMBO Rep., 17, 300, 10.15252/embr.201541486 · DOI
  34. Ye, 2015, Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer’s disease patient brains, Hum. Mol. Genet., 24, 2938, 10.1093/hmg/ddv056 · DOI · Paper page

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Metadata

Authors
Martín-Maestro, P., Gargini, R., A. Sproul, A., García, E., Antón, L. C., Noggle, S., Arancio, O., Avila, J., & García-Escudero, V.
Venue
Frontiers in Molecular Neuroscience
Publisher
Frontiers Media SA
Published
2017-09-14
Volume
10
ISSN
1662-5099
DOI
10.3389/fnmol.2017.00291
PMC
PMC5603661
Cited by
120
References
8
Funders
Ministerio de Economà-a y Competitividad (SAF 2011 program, project 24841, SAF2016 program, project 79607-R, BES-2012-055068)

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