Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

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N , O -Benzamide difluoroboron complexes as near-infrared probes for the detection of β-amyloid and tau fibrils

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CRISPR/Cas9 and iPSC-Based Therapeutic Approaches in Alzheimer’s Disease

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Drug Development in Alzheimer’s Disease: The Contribution of PET and SPECT

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Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer’s disease: a preclinical study in rTg4510 mice

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Regardless of the Brewing Conditions, Various Types of Tea are a Source of Acetylcholinesterase Inhibitors

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Early neurotransmission impairment in non-invasive Alzheimer Disease detection

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Therapeutic Strategies Targeting Amyloid-β Receptors and Transporters in Alzheimer’s Disease

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CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes

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Novel Biomarkers of Alzheimer's Disease: Based Upon N-methyl-D-aspartate Receptor Hypoactivation and Oxidative Stress

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A literature review of MRI techniques used to detect amyloid-beta plaques in Alzheimer’s disease patients

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Application of CRISPR/Cas9 in the management of Alzheimer’s disease and Parkinson’s disease: a review

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Neuregulin1β improves both spatial and associative learning and memory in Alzheimer model of rats possibly through signaling pathways other than Erk1/2

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Myricetin Restores Aβ-Induced Mitochondrial Impairments in N2a-SW Cells

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Relationship between Cognitive Dysfunction and Age-Related Variability in Oxidative Markers in Isolated Mitochondria of Alzheimer’s Disease Transgenic Mouse Brains

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Research progress of the CXCR4 mechanism in Alzheimer's disease

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Dieta mediterránea y sus efectos benéficos en la prevención de la enfermedad de Alzheimer

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Diet as a Risk Factor for Cognitive Decline in African Americans and Caucasians with a Parental History of Alzheimer's Disease: A Cross-Sectional Pilot Study Dietary Patterns

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The Role of Retromer in Alzheimer’s Disease

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Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice

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Aβ, Tau, and α-Synuclein aggregation and integrated role of PARK2 in the regulation and clearance of toxic peptides

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Nanomodulators That Target Alzheimer’s Disease: A Review

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Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease

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Palmatine Protects PC12 Cells and Mice from Aβ25-35-Induced Oxidative Stress and Neuroinflammation via the Nrf2/HO-1 Pathway

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Chromones: privileged scaffolds for the production of multi-target-directed-ligand agents for the treatment of Alzheimer’s disease

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Novel compound VB‐037 inhibits A&bgr; aggregation and promotes neurite outgrowth through enhancement of HSP27 and reduction of P38 and JNK‐mediated inflammation in cell models for Alzheimer's disease

Chiu, Y.-J., Hsieh, Y.-H., Lin, T.-H., Lee, G.-C., Hsiu, M.-H.-L., Sun, Y.-C., Chen, C.-M., Chang, K.-H., & Lee-Chen, G. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.01.021 · Cited by 21

Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease

Wang, X.-X., Xie, F., Jia, C.-C., Yan, N., Zeng, Y.-L., Wu, J.-D., & Liu, Z.-P. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113821 · Cited by 23

Alzheimer’s disease: from early pathogenesis to novel therapeutic approaches

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Advances in Studies on Stroke-Induced Secondary Neurodegeneration (SND) and Its Treatment

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Intracerebroventricularly Injected Streptozotocin Exerts Subtle Effects on the Cognitive Performance of Long-Evans Rats

Gáspár, A., Hutka, B., Ernyey, A. J., Tajti, B. T., Varga, B. T., Zádori, Z., & Gyertyán, I. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.662173 · Cited by 21

Design, synthesis and evaluation of novel scutellarin and scutellarein-N,N-bis-substituted carbamate-l-amino acid derivatives as potential multifunctional therapeutics for Alzheimer’s disease

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Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway

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Protective effects of Radix Stellariae extract against Alzheimer's disease via autophagy activation in Caenorhabditis elegans and cellular models

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Cognitive ‘Omics’: Pattern-Based Validation of Potential Drug Targets

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Peptides isolated from animal venom as a platform for new therapeutics for the treatment of Alzheimer's disease

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CDK5 Participates in Amyloid-β Production by Regulating PPARγ Phosphorylation in Primary Rat Hippocampal Neurons

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Combined strategies for optimizing BODIPY-based near-infrared fluorescent probe targeting Aβ oligomers

Akasaka, T., Watanabe, H., & Ono, M. (2024) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2024.136132 · Cited by 19

Tetrapeptide Ac-HAEE-NH2 Protects α4β2 nAChR from Inhibition by Aβ

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The Association of Periodontitis and Alzheimer’s Disease: How to Hit Two Birds with One Stone

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Hypoxia and the Kynurenine Pathway: Implications and Therapeutic Prospects in Alzheimer’s Disease

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Molecular insights into the inhibition of early stages of Aβ peptide aggregation and destabilization of Alzheimer's Aβ protofibril by dipeptide D-Trp-Aib: A molecular modelling approach

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Animal models of Alzheimer’s disease: An origin of innovative treatments and insight to the disease's etiology

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Synthesis, Properties, and Biomedical Application of Dicationic Gemini Surfactants with Dodecane Spacer and Carbamate Fragments

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Modulation of microRNAs through Lifestyle Changes in Alzheimer’s Disease

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Drp1: Focus on Diseases Triggered by the Mitochondrial Pathway

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Fuzhisan ameliorates Aβ production and tau phosphorylation in hippocampal of 11 month old APP/PS1 transgenic mice: A Western blot study

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Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study

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Non-conventional compounds with potential therapeutic effects against Alzheimer’s disease

de Castro, A. A., Soares, F. V., Pereira, A. F., Polisel, D. A., Caetano, M. S., Leal, D. H. S., da Cunha, E. F. F., Nepovimová, E., Kuča, K., & Ramalho, T. C. (2019) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2019.1608823 · Cited by 20

Early active immunization with Aβ 3–10 -KLH vaccine reduces tau phosphorylation in the hippocampus and protects cognition of mice

Cao, Y., Wang, J.-C., Zhu, K., Zhang, H., Wang, G., & Liu, H. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.266061 · Cited by 20

An integrated approach to unravel a putative crosstalk network in Alzheimer’s disease and Parkinson’s disease

Bisht, I., Ambasta, R. K., & Kumar, P. (2020) · Neuropeptides · doi:10.1016/j.npep.2020.102078 · Cited by 20

Exploring the role of mitochondrial proteins as molecular target in Alzheimer’s disease

Chadha, S., Behl, T., Sehgal, A., Kumar, A., & BUNGAU, S. G. (2020) · Mitochondrion · doi:10.1016/j.mito.2020.11.008 · Cited by 20

Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease

Hwang, J., Keum, M., Choe, Y. M., Suh, G., Choi, H., Lee, B. C., Kim, S. G., Kim, H. S., Yi, D., & Kim, J. W. (2025) · Journal of Ginseng Research · doi:10.1016/j.jgr.2025.03.011 · Cited by 21

Paper-Based Detection Device for Alzheimer’s Disease—Detecting β-amyloid Peptides (1–42) in Human Plasma

Sung, W.-H., Hung, J., Lin, Y.-J., & Cheng, C. (2020) · Diagnostics · doi:10.3390/diagnostics10050272 · Cited by 19

Digital Intervention for the Management of Alzheimer’s Disease

Manchanda, N., Aggarwal, A., Setya, S., & Talegaonkar, S. (2022) · Current Alzheimer Research · doi:10.2174/1567205020666230206124155 · Cited by 20

Getting ahead of Alzheimer’s disease: early intervention with focused ultrasound

Noel, R. L., Gorman, S. L., Batts, A. J., & Konofagou, E. E. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1229683 · Cited by 20

Anti-Alzheimer’s Materials Isolated from Marine Bio-resources: A Review

Rathnayake, A. U., Abuine, R., Kim, Y., & Byun, H. (2019) · Current Alzheimer Research · doi:10.2174/1567205016666191024144044 · Cited by 20

Possible mechanism of Vitis vinifera L. flavones on neurotransmitters, synaptic transmission and related learning and memory in Alzheimer model rats

Ma, L., Xiao, H., Wen, J., Liu, Z., He, Y., & Yuan, F. (2018) · Lipids in Health and Disease · doi:10.1186/s12944-018-0708-6 · Cited by 19

Tau proteins and senescent Cells: Targeting aging pathways in Alzheimer’s disease

Singh, M., Ali, H., Jyothi, S. R., Kaur, I., Kumar, S., Sharma, N., Prasad, G. V. S., Pramanik, A., Almalki, W. H., & Imran, M. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149165 · Cited by 18

Catechol-Type Flavonoids from the Branches of Elaeagnus glabra f. oxyphylla Exert Antioxidant Activity and an Inhibitory Effect on Amyloid-β Aggregation

Kim, Y. J., Sohn, E., Kim, J., Na, M., & Jeong, S. (2020) · Molecules · doi:10.3390/molecules25214917 · Cited by 18

Implications for microglial sex differences in tau-related neurodegenerative diseases

Doust, Y. V., King, A. E., & Ziebell, J. M. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.03.010 · Cited by 18

Sodium–calcium exchanger isoform-3 targeted Withania somnifera (L.) Dunal therapeutic intervention ameliorates cognition in the 5xFAD mouse model of Alzheimer’s disease

Afewerky, H. K., Li, H., Zhang, T., Li, X., Mahaman, Y. A. R., Duan, L., Qin, P., Zheng, J., Pei, L., & Lu, Y. (2022) · Scientific Reports · doi:10.1038/s41598-022-05568-2 · Cited by 18

Honeys as Possible Sources of Cholinesterase Inhibitors

Szwajgier, D., Baranowska‐Wójcik, E., Winiarska‐Mieczan, A., & Gajowniczek-Ałasa, D. (2022) · Nutrients · doi:10.3390/nu14142969 · Cited by 18

The Zebrafish Equivalent of Alzheimer’s Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress

Ebrahimie, E., Nik, S. H. M., Newman, M., der Hoek, M. B. V., & Lardelli, M. T. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150678 · Cited by 19

Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of β-amyloid peptide

Zhang, J.-X., Lai, Y.-H., Mi, P., Dai, X., Zhang, R., Zhang, Z., Zhang, S., Zhang, X., Zhang, X., Yang, B., et al. (2019) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0560-6 · Cited by 18

Fluorescent Dopamine–Tryptophan Nanocomposites as Dual-Imaging and Antiaggregation Agents: New Generation of Amyloid Theranostics with Trimeric Effects

Sharma, M., Tiwari, V., Shukla, S., & Panda, J. J. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c13223 · Cited by 18

Experimental study on the neurotoxic effect of β-amyloid on the cytoskeleton of PC12 cells

Wang, L., Cao, J., Shi, Z., Fan, W., Liu, H., Deng, J., & Deng, J. (2018) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2018.3467 · Cited by 18

The Evolution of AChE Inhibitors in Alzheimer's Disease: From Single‐Target to Multi‐Target Ligands

Mehta, N. V., Kapadia, A., Khambete, M., & Abhyankar, A. N. (2025) · ChemBioChem · doi:10.1002/cbic.202500053 · Cited by 20

Identification of ellagic acid and urolithins as natural inhibitors of Aβ25–35-induced neurotoxicity and the mechanism predication using network pharmacology analysis and molecular docking

Li, H.-L., Zhang, S., Ren, Y., Zhou, J., Zhou, Y.-X., Huang, W., Piao, X., Yang, Z., Wang, S., & Ge, Y. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.966276 · Cited by 17

Neuroprotective Effect of NO-Delivery Dinitrosyl Iron Complexes (DNICs) on Amyloid Pathology in the Alzheimer’s Disease Cell Model

Chuang, W.-H., Chou, Y.-T., Chen, Y.-H., Kuo, T.-H., Liaw, W., Lu, T., Kao, C.-F., & Wang, Y. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00348 · Cited by 17

Enantiomeric lignans with anti-β-amyloid aggregation activity from the twigs and leaves of Pithecellobium clypearia Benth

Wang, Y.-X., Zhou, L., Wang, J., Lin, B., Wang, X., Huang, X., & Song, S. (2018) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2018.02.001 · Cited by 17

Unravelling neurological disorders through metallomics-based approaches

de Jesus, J. R., & Arruda, M. A. Z. (2020) · Metallomics · doi:10.1039/d0mt00234h · Cited by 18

Elevation of phospholipase C-β1 expression by amyloid-β facilitates calcium overload in neuronal cells

Park, J., Kim, S. H., Kim, Y. J., Kim, I. H., Oh, Y., Choi, K. Y., Kim, B. C., Lee, K. H., & Song, W. K. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147924 · Cited by 17

Qualitative assessment of functional module detectors on microarray and RNASeq data

Jha, M., Guzzi, P. H., & Roy, S. (2019) · Network Modeling Analysis in Health Informatics and Bioinformatics · doi:10.1007/s13721-018-0180-2 · Cited by 17

Combination Therapy for the Treatment of Alzheimer’s Disease: Recent Progress and Future Prospects

Shirbhate, E., Patel, V. K., Tiwari, P., Kore, R., Veerasamy, R., Mishra, A., & Rajak, H. (2022) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026622666220907114443 · Cited by 18

Oxidative stress is associated with Aβ accumulation in chronic sleep deprivation model

Beiyu, Z., Zhou, R., Zhao, Y., Wei, S., Peng, L., Meng, W., Peng, W., Yuan, Y., & Qu, Q. (2024) · Brain Research · doi:10.1016/j.brainres.2024.148776 · Cited by 16

New Multitarget Rivastigmine–Indole Hybrids as Potential Drug Candidates for Alzheimer’s Disease

Bon, L., Banaś, A., Dias, I., Melo-Marques, I., Cardoso, S. M., Chaves, S., & Santos, M. A. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16020281 · Cited by 16

Rodent Models of Alzheimer’s Disease: Past Misconceptions and Future Prospects

Collins, H. M., & Greenfield, S. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116222 · Cited by 21

Amyloid beta peptide-degrading microbial enzymes and its implication in drug design

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Validation by Magnetic Resonance Imaging of the Diagnostic Potential of a Heptapeptide-Functionalized Imaging Probe Targeted to Amyloid-β and Able to Cross the Blood-Brain Barrier

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