Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

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Donepezil-loaded PLGA-b-PEG Nanoparticles Enhance the Learning and Memory Function of Beta-Amyloid Rat Model of Alzheimer’s Disease

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Biotechnological potential of actinomycetes in the 21st century: a brief review

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Design, synthesis, and biological evaluation of tetrahydropyrimidine analogue as GSK-3β/Aβ aggregation inhibitor and anti-Alzheimer’s agent

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Pathways to Alzheimer’s Disease: The Intersecting Roles of Clusterin and Apolipoprotein E in Amyloid-β Regulation and Neuronal Health

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Antioxidative stress effect of epicatechin and catechin induced by Aβ25–35 in rats and use of the electrostatic potential and the Fukui function as a tool to elucidate specific sites of interaction

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Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand To Treat Alzheimer’s Disease

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How glutamatergic synapse loss affects the firing rhythm of DG-CA3 model related with Alzheimer’s disease

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Total scale analysis of organic acids and their role to mitigate Alzheimer's disease

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Preparation and in vitro activity of single chain antibodies against Alzheimer's disease

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Dementia and neurodegenerative disorder: An introduction

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Synthesis and evaluation of butylphthalide-scutellarein hybrids as multifunctional agents for the treatment of Alzheimer's disease

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Associations of Lipoprotein(a) Level with Cerebral Small Vessel Disease in Patients with Alzheimer’s Disease

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Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation

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Biofluid biomarkers for Alzheimer’s disease: past, present, and future

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1,3,5-Triazine: A Promising Molecular Scaffold for Novel Agents for the Treatment of Alzheimer’s Disease

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Huprine Y – Tryptophan heterodimers with potential implication to Alzheimer’s disease treatment

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Prioritizing disease biomarkers using functional module based network analysis: A multilayer consensus driven scheme

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Sulforaphane inhibits the production of Aβ partially through the activation of Nrf2-regulated oxidative stress

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Advances in Bioactive Compounds from Plants and Their Applications in Alzheimer’s Disease

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A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease

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miRNA‐211‐5p inhibition enhances the protective effect of hucMSC‐derived exosome in Aβ1‐40‐induced SH‐SY5Y cells by increasing NEP expression

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Electrochemical detection of Zn(II)-induced amyloid-β aggregation: Insights into aggregation mechanisms

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3H-1,2-dithiole-3-thione protects PC12 cells against amyloid beta 1–42 (Aβ1–42) induced apoptosis via activation of the ERK1/2 pathway

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Binding Models of Aβ42 Peptide with Membranes Explored by Molecular Simulations

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Recent Modifications of Anti-dementia Agents Focusing on Tacrine and/or Donepezil Analogs

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Heparin Modulates the Kinetics of Zinc-Induced Aggregation of Amyloid-β Peptides

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Vestibular Function and Beta-Amyloid Deposition in the Baltimore Longitudinal Study of Aging

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Structural significance of Neprylysin from Streptococcus suis GZ1 in the degradation of Aβ peptides, a causative agent in Alzheimer's disease

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Associations of sleep duration and daytime sleepiness with plasma amyloid beta and cognitive performance in cognitively unimpaired, middle-aged and older African Americans

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Alimentary Treatment with Trehalose in a Pharmacological Model of Alzheimer’s Disease in Mice: Effects of Different Dosages and Treatment Regimens

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Sodium tanshinone IIA sulfonate improves cognitive impairment via regulating Aβ transportation in AD transgenic mouse model

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Near-infrared irradiation controlled thermo-switchable polymeric photosensitizer against β-amyloid fibrillation

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Protective Effects of Heat-Killed Ruminococcus albus against β-Amyloid-Induced Apoptosis on SH-SY5Y Cells

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Effect of polysaccharides from Vitis vinifera L. on NF-κB/IκB-α signal pathway and inflammatory factors in Alzheimer's model rats

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Triggering Innate Immune Receptors as New Therapies in Alzheimer’s Disease and Multiple Sclerosis

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Anodal transcranial direct current stimulation alleviates cognitive impairment in an APP/PS1 model of Alzheimer’s disease in the preclinical stage

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Molecular dynamics approach for behavior assessment of chitosan nanoparticles in carrying of donepezil and rivastigmine drug molecules

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Protein kinases as therapeutic targets for Alzheimer’s disease: a brief review

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Substance P mitigates lipopolysaccharide induced cognitive impairment in rats in a dose dependent manner

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Gene Ontology curation of the blood–brain barrier to improve the analysis of Alzheimer’s and other neurological diseases

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A critical review on the role of nanotheranostics mediated approaches for targeting β amyloid in Alzheimer’s

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The roles of natural triterpenoid saponins against Alzheimer's disease

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Active immunization with norovirus P particle-based amyloid-β chimeric protein vaccine induces high titers of anti-Aβ antibodies in mice

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Design, Synthesis, and Biological Activity of Conformationally Restricted Analogues of Silibinin

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N,N′-1,10-Bis(Naringin) Triethylenetetraamine, Synthesis and as a Cu(II) Chelator for Alzheimer’s Disease Therapy

Guo, L., & Sun, B. (2020) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b20-00574 · Cited by 9

Design, Synthesis, Biological Evaluation and Molecular Dynamics Simulations Study of Genistein‐ O ‐1,3,5‐Triazine Derivatives as Multifunctional Anti‐Alzheimer Agents

Zou, J., Qian, J., Liu, S., Li, R., Zhang, X., Yang, S., Liu, Y., Liu, W., Ma, S., & Shi, D. (2022) · ChemistrySelect · doi:10.1002/slct.202203997 · Cited by 9

Total flavonoids of Cynomorium songaricum attenuates cognitive defects in an Aβ1-42-induced Alzheimer’s disease rat model by activating BDNF/TrkB signaling transduction

Gu, Z., Lv, X., Yan, G., Qi, M., & Ge, B. (2023) · Neuroreport · doi:10.1097/wnr.0000000000001960 · Cited by 9

Implications of Successful Symptomatic Treatment in Parkinson’s Disease for Therapeutic Strategies of Alzheimer’s Disease

Zhao, L., Cheng, X., & Zhong, C. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00450 · Cited by 9

Three-dimensional quantitative analysis of amyloid plaques in the whole brain with high voxel resolution

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Novel 1,2,4‐triazole derivatives containing the naphthalene moiety as selective butyrylcholinesterase inhibitors: Design, synthesis, and biological evaluation

Aslan, E. K., Sezer, A., Küçükkılınç, T. T., & Palaska, E. (2024) · Archiv der Pharmazie · doi:10.1002/ardp.202400406 · Cited by 8

Leisure Activity Interventions on Cognition in Mild Cognitive Impairment Patients: A Meta-Analysis

He, X., Liu, C., Li, Z., & Cai, X. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s536627 · Cited by 8

Identification of key neutrophil extracellular trap genes in Alzheimer's disease

Pan, H., Wang, G., Bi, Z., Lai, C., & Wang, M. (2024) · Journal of Alzheimer s Disease · doi:10.1177/13872877241295374 · Cited by 9

Discovery of new dual butyrylcholinesterase (BuChE) inhibitors and 5-HT7 receptor antagonists as compounds used to treat Alzheimer’s disease symptoms

Kułaga, D., Drabczyk, A. K., Zaręba, P., Jaśkowska, J., Satała, G., Zaręba, P., Więckowska, A., de Candia, M., Purgatorio, R., Boguszewska‐Czubara, A., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.117995 · Cited by 8

Poly (n-butyl cyanoacrylate) as a nanocarrier for rivastigmine transport across the blood–brain barrier in Alzheimer’s disease treatment: a perspective from molecular dynamics simulations

Mousavi, S. V., & Hashemianzadeh, S. M. (2018) · Journal of Molecular Modeling · doi:10.1007/s00894-018-3799-0 · Cited by 8

The mitochondria/caspase-dependent apoptotic pathway plays a role in the positive effects of a power frequency electromagnetic field on Alzheimer’s disease neuronal model

Zuo, H., Liu, X., Li, Y., Wang, D., Hao, Y., Yu, C., Xu, X., Peng, R., & Song, T. (2020) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2020.101857 · Cited by 8

Cu 2+ -Induced self-assembly and amyloid formation of a cyclic d , l -α-peptide: structure and function

Klose, D., Vemulapalli, S. P. B., Richman, M., Rudnick‐Glick, S., Aisha, V., Abayev, M., Chemerovski‐Glikman, M., Shviro, M., Zitoun, D. O., Majer, K., et al. (2022) · Physical Chemistry Chemical Physics · doi:10.1039/d1cp05415e · Cited by 8

Ambient Benzo[a]pyrene’s Effect on Kinetic Modulation of Amyloid Beta Peptide Aggregation: A Tentative Association between Ultrafine Particulate Matter and Alzheimer’s Disease

Kaumbekova, S., Torkmahalleh, M. A., & Shah, D. (2022) · Toxics · doi:10.3390/toxics10120786 · Cited by 8

Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice

Daini, E., Vandini, E., Bodria, M., Liao, W., Baraldi, C., Secco, V., Ottani, A., Zoli, M., Giuliani, D., & Vilella, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1082036 · Cited by 9

Aberrant Expression of GABA-Related Genes in the Hippocampus of 3xTg-AD Model Mice from the Early to End Stages of Alzheimer’s Disease

Mori, H., Yoshino, Y., Iga, J., Ochi, S., Funahashi, Y., Yamazaki, K., Kumon, H., Ozaki, Y., & Ueno, S. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230078 · Cited by 8

Role of Neurexins in Alzheimer's Disease

Medina-Samamé, A., Paller, É., Bril, M. R., Archvadze, A., Simões-Abade, M. B. C., Cayuela, P. E., & LeMaoult, C. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0169-23.2023 · Cited by 8

The advancing role of fluorogens with AIE characteristics in drug screening

You, J., Ma, Y., Song, H., Hou, J., & Zhao, E. (2024) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2024.117886 · Cited by 8

The effect of geniste on Aβ25–35-induced PC12 cell apoptosis through the JNK-dependent Fas pathway

Zheng, Y., You, F., Li, Q., Chen, J., & Yang, H. (2016) · Food & Function · doi:10.1039/c6fo00071a · Cited by 8

The SNK and SPAR signaling pathway changes in hippocampal neurons treated with amyloid-beta peptide in vitro

Sui, H. X., Zhan, L., Niu, X., Liang, L., & Li, X. (2017) · Neuropeptides · doi:10.1016/j.npep.2017.03.001 · Cited by 8

Modulating Aβ Fibrillogenesis with ‘Trojan’ peptides

Pandey, G., Morla, S., Kumar, S., & Ramakrishnan, V. (2020) · Neuropeptides · doi:10.1016/j.npep.2020.102030 · Cited by 8

Levels of Amyloid Beta (Aβ) Expression in the Caenorhabditis elegans Neurons Influence the Onset and Severity of Neuronally Mediated Phenotypes

Sirwani, N., Hedtke, S. M., Grant, K., McColl, G., & Grant, W. N. (2024) · Cells · doi:10.3390/cells13181598 · Cited by 8

Towards Better and More Valid Zebrafish Models of Alzheimer's Disease: A Scientific Tribute to Prof. Mikhail I. Aghajanov

Kotova, M. M., Stewart, A., Grigoryan, A., Shariff, S., Mirzaei, F., Kantawala, B., Dilbaryan, K., de Abreu, M. S., Galstryan, D. S., Cui, J., et al. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70090 · Cited by 7

Recent advances in nanomaterial-based biosensors for Alzheimer's disease diagnosis: a review

Liu, Q., Xu, X., & Zheng, T. (2025) · Chemical Communications · doi:10.1039/d5cc02469b · Cited by 7

Biomaterials for biomarker imaging and detection

Wang, Y., Huang, X., Wu, G., Wu, W., Li, S., Su, C., Li, L., & Lv, Q. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.07.049 · Cited by 10

Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies

Jing, L., Wei, W., Meng, B., Chantegreil, F., Nachon, F., Martı́nez, A., Wu, G., Zhao, H., Song, Y., Kang, D., et al. (2023) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2023.106465 · Cited by 7

SiC Electrochemical Sensor Validation for Alzheimer Aβ42 Antigen Detection

Montero-Arévalo, B., Seufert, B., Hossain, M. S., Bernardin, E. K., Takshi, A. I., Saddow, S. E., & Schettini, N. (2023) · Micromachines · doi:10.3390/mi14061262 · Cited by 7

Sulphated Fucooligosaccharide from Sargassum Horneri: Structural Analysis and Anti-Alzheimer Activity

Zhang, L., Zhang, H.-Z., Liu, Y.-W., Tang, M. M., Jiang, Y., Li, F.-N., Guan, L., & Jin, Q. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04107-x · Cited by 7

Tailored Melatonin- and Donepezil-Based Hybrids Targeting Pathognomonic Changes in Alzheimer’s Disease: An In Vitro and In Vivo Investigation

Mihaylova, R., Angelova, V. T., Tchekalarova, J. D., Atanasova, D., Ivanova, P., & Simeonova, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115969 · Cited by 7

Corilagin improves cognitive impairment in APP/PS1 mice by reducing Aβ generation and enhancing synaptic plasticity

Chen, L., Zhuang, Z., Duan, H., Lv, D., Hong, S., He, B., He, B., & Shen, Z. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176893 · Cited by 7

Advances in the Understanding of ocular and nasal lymphatics

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