The effectiveness of tonsillectomy and adenoidectomy in the treatment of pediatric obstructive sleep apnea/hypopnea syndrome: a meta-analysis
Abstract
OBJECTIVE: Present and evaluate the currently available literature reporting on the effectiveness of adenotonsillectomy (T/A) in treating obstructive sleep apnea/hypopnea syndrome (OSAHS) in uncomplicated pediatric patients. STUDY DESIGN AND SETTING: Systematic review of the literature and meta-analysis of the reduction of the polysomnogram (PSG)-measured Apnea Hypopnea Index (AHI events/hour) resulting from T/A and the overall success rate of T/A in normalizing PSG measurements (%). RESULTS: Fourteen studies met the inclusion criteria. Mean sample size was 28. All were case series (level 4 evidence). The summary change in AHI was a reduction of 13.92 events per hour (random effects model 95% CI 10.05-17.79, P < 0.001) from T/A. The summary success rate of T/A in normalizing PSG was 82.9% (random effects model 95% CI 76.2%-89.5%, P < 0.001). CONCLUSION/SIGNIFICANCE: T/A is effective in the treatment of OSAHS. However, success rates are far below 100%, which could have far-reaching pediatric public health consequences. EBM RATING: B-2a.
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Adenotonsillectomy is curative in 25% to 75% of pediatric obstructive sleep apnea patients.
“However, some studies 8 9 10 have reported that adenotonsillectomy is curative in 25% to 75% of the patients.”
From Mandibular Advancement Appliances in Pediatric Obstructive Sleep Apnea: An Umbrella Review (2023) · cites this paper as [8]
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- Authors
- Brietzke, S. E., & Gallagher, D.
- Affiliations
- Walter Reed National Military Medical Center (US)
- Corresponding author
- Brietzke, Scott E.
- ORCID
- Brietzke, Scott E.
- Venue
- Otolaryngology–Head and Neck Surgery
- Publisher
- Wiley
- Published
- 2006-06
- Volume
- 134
- Issue
- 6
- Pages
- 979-984
- ISSN
- 0161-6439 (ISSN-L)
- 0194-5998
- 1097-6817
- OpenAlex
- W2001059780
- Cited by
- 423
- References
- 22
- Citations by year
- 2026: 15 · 2025: 12 · 2024: 15 · 2023: 17 · 2022: 10 · 2021: 23 · 2020: 20 · 2019: 26 · 2018: 22 · 2017: 21 · 2016: 30 · 2015: 29 · 2014: 27 · 2013: 21 · 2012: 33
- FWCI
- 12.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Otolaryngology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
- Keywords
- adenotonsillectomy, tonsillectomy, adenoidectomy, obstructive sleep apnea-hypopnea syndrome, pediatric sleep apnea, apnea-hypopnea index, polysomnography, surgical outcomes
- MeSH terms
- Adenoidectomy, Child, Child, Preschool, Female, Humans, Male, Palate, Soft, Tonsillectomy, Treatment Outcome, Sleep Apnea, Obstructive
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