Cited by 423Obstructive Sleep Apnea ResearchSleep and related disordersNasal Surgery and Airway Studies

The effectiveness of tonsillectomy and adenoidectomy in the treatment of pediatric obstructive sleep apnea/hypopnea syndrome: a meta-analysis

Brietzke, Scott E., Gallagher, Daniel·2006·Otolaryngology–Head and Neck Surgery

Abstract

OBJECTIVE: Present and evaluate the currently available literature reporting on the effectiveness of adenotonsillectomy (T/A) in treating obstructive sleep apnea/hypopnea syndrome (OSAHS) in uncomplicated pediatric patients. STUDY DESIGN AND SETTING: Systematic review of the literature and meta-analysis of the reduction of the polysomnogram (PSG)-measured Apnea Hypopnea Index (AHI events/hour) resulting from T/A and the overall success rate of T/A in normalizing PSG measurements (%). RESULTS: Fourteen studies met the inclusion criteria. Mean sample size was 28. All were case series (level 4 evidence). The summary change in AHI was a reduction of 13.92 events per hour (random effects model 95% CI 10.05-17.79, P < 0.001) from T/A. The summary success rate of T/A in normalizing PSG was 82.9% (random effects model 95% CI 76.2%-89.5%, P < 0.001). CONCLUSION/SIGNIFICANCE: T/A is effective in the treatment of OSAHS. However, success rates are far below 100%, which could have far-reaching pediatric public health consequences. EBM RATING: B-2a.

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Crossref · 10.1016/j.otohns.2006.02.033

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Authors
Brietzke, S. E., & Gallagher, D.
Affiliations
Walter Reed National Military Medical Center (US)
Corresponding author
Brietzke, Scott E.
Venue
Otolaryngology–Head and Neck Surgery
Publisher
Wiley
Published
2006-06
Volume
134
Issue
6
Pages
979-984
ISSN
  • 0161-6439 (ISSN-L)
  • 0194-5998
  • 1097-6817
OpenAlex
W2001059780
Cited by
423
References
22
Citations by year
2026: 15 · 2025: 12 · 2024: 15 · 2023: 17 · 2022: 10 · 2021: 23 · 2020: 20 · 2019: 26 · 2018: 22 · 2017: 21 · 2016: 30 · 2015: 29 · 2014: 27 · 2013: 21 · 2012: 33
FWCI
12.81
Type
journal article
Language
en
Open access
closed
Locations
  • Otolaryngology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
Keywords
adenotonsillectomy, tonsillectomy, adenoidectomy, obstructive sleep apnea-hypopnea syndrome, pediatric sleep apnea, apnea-hypopnea index, polysomnography, surgical outcomes
MeSH terms
Adenoidectomy, Child, Child, Preschool, Female, Humans, Male, Palate, Soft, Tonsillectomy, Treatment Outcome, Sleep Apnea, Obstructive

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