Cited by 51Plant Stress Responses and ToleranceRedox biology and oxidative stressPhotosynthetic Processes and Mechanisms

Regulation of antioxidant defense and glyoxalase systems in cyanobacteria

Rai, Ruchi, Singh, Shilpi, Rai, Krishna Kumar, Raj, Alka, Sriwastaw, Sonam, Rai, L.C.·2021·Plant Physiology and Biochemistry

Abstract

Oxidative stress is common consequence of abiotic stress in plants as well as cyanobacteria caused by generation of reactive oxygen species (ROS), an inevitable product of respiration and photosynthetic electron transport. ROS act as signalling molecule at low concentration however, when its production exceeds the endurance capacity of antioxidative defence system, the organisms suffer oxidative stress. A highly toxic metabolite, methylglyoxal (MG) is also produced in cyanobacteria in response to various abiotic stresses which consequently augment the ensuing oxidative damage. Taking recourse to the common lineage of eukaryotic plants and cyanobacteria, it would be worthwhile to explore the regulatory role of glyoxalase system and antioxidative defense mechanism in combating abiotic stress in cyanobacteria. This review provides comprehensive information on the complete glyoxalase system (GlyI, GlyII and GlyIII) in cyanobacteria. Furthermore, it elucidates the recent understanding regarding the production of ROS and MG, noteworthy link between intracellular MG and ROS and its detoxification via synchronization of antioxidants (enzymatic and non-enzymatic) and glyoxalase systems using glutathione (GSH) as common co-factor.

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Crossref · 10.1016/j.plaphy.2021.09.037

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307 of 307 references verified0 citation errors · 0 not checkable

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Authors
Rai, R., Singh, S., Rai, K. K., Raj, A., Sriwastaw, S., & Rai, L. C.
Affiliations
Banaras Hindu University (IN)
Corresponding author
Rai, L.C.
Venue
Plant Physiology and Biochemistry
Publisher
Elsevier BV
Published
2021-11
Volume
168
Pages
353-372
ISSN
0981-9428 (ISSN-L)
OpenAlex
W3205425525
Cited by
51
References
309
Citations by year
2026: 5 · 2025: 15 · 2024: 14 · 2023: 11 · 2022: 6
FWCI
0.74
Type
journal article
Language
en
Open access
closed
Locations
  • Plant Physiology and Biochemistry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
Keywords
cyanobacteria, oxidative stress, reactive oxygen species, methylglyoxal, glyoxalase system, antioxidant defense, glutathione, abiotic stress, glyoxalase I, glyoxalase II, detoxification
MeSH terms
Cyanobacteria, Antioxidants, Plants, Pyruvaldehyde, Reactive Oxygen Species

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