The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health
Open accessAbstract
Carotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic organisms and some non-photosynthetic prokaryotes and fungi. With some notable exceptions, animals (including humans) do not produce carotenoids de novo but take them in their diets. In photosynthetic systems carotenoids are essential for photoprotection against excess light and contribute to light harvesting, but perhaps they are best known for their properties as natural pigments in the yellow to red range. Carotenoids can be associated to fatty acids, sugars, proteins, or other compounds that can change their physical and chemical properties and influence their biological roles. Furthermore, oxidative cleavage of carotenoids produces smaller molecules such as apocarotenoids, some of which are important pigments and volatile (aroma) compounds. Enzymatic breakage of carotenoids can also produce biologically active molecules in both plants (hormones, retrograde signals) and animals (retinoids). Both carotenoids and their enzymatic cleavage products are associated with other processes positively impacting human health. Carotenoids are widely used in the industry as food ingredients, feed additives, and supplements. This review, contributed by scientists of complementary disciplines related to carotenoid research, covers recent advances and provides a perspective on future directions on the subjects of carotenoid metabolism, biotechnology, and nutritional and health benefits.
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A standardised static in vitro digestion method suitable for food – an international consensus
Minekus, M., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C., Carrière, F., Boutrou, R., Corredig, M., Dupont, D., et al. (2014) · Food Funct. · doi:10.1039/c3fo60702j · Cited by 5,824
Inflammatory Mechanisms in Obesity
Gregor, M. F., & Hotamisligil, G. S. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101322 · Cited by 3,754
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., Keogh, J. P., Meyskens, F. L., Valanis, B., Williams, J. H., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605023341802 · Cited by 3,638
Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi
Akiyama, K., Matsuzaki, K.-I., & Hayashi, H. (2005) · Nature · doi:10.1038/nature03608 · Cited by 2,429
Potential Role of Carotenoids as Antioxidants in Human Health and Disease
Fiedor, J., & Burda, K. (2014) · Nutrients · doi:10.3390/nu6020466 · Cited by 1,420
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Z., Irie, H. Y., Gao, S., Puigserver, P., & Brugge, J. S. (2009) · Nature · doi:10.1038/nature08268 · Cited by 1,031
Oxidative stress in obesity: A critical component in human diseases
Marseglia, L., Manti, S., D’Angelo, G., Nicotera, A., Parisi, E., Di Rosa, G., Gitto, E., & Arrigo, T. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms16010378 · Cited by 933
A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A
Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., & Sun, H. (2007) · Science · doi:10.1126/science.1136244 · Cited by 836
Antioxidant and Prooxidant Properties of Carotenoids
Young, A. J., & Lowe, G. M. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2000.2149 · Cited by 822
Carotenoids: biochemistry, pharmacology and treatment
Milani, A., Basirnejad, M., Shahbazi, S., & Bolhassani, A. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13625 · Cited by 781
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Spirulina for the Food and Functional Food Industries
Lafarga, T., Fernández-Sevilla, J. M., González-López, C., & Acién-Fernández, F. G. (2020) · Food Research International · doi:10.1016/j.foodres.2020.109356 · Cited by 417
Qiu, Z., Chen, X., Geng, T., Wan, Z., Lu, Q., Li, L., Zhu, K., Zhang, X., Liu, Y., Lin, X., et al. (2022) · Diabetes Care · doi:10.2337/dc21-2371 · Cited by 202
Murador, D. C., de Souza Mesquita, L. M., Vannuchi, N., Braga, A. R. C., & de Rosso, V. V. (2019) · Current Opinion in Food Science · doi:10.1016/j.cofs.2019.03.002 · Cited by 158
Canthaxanthin, a Red-Hot Carotenoid: Applications, Synthesis, and Biosynthetic Evolution
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Metadata
- Authors
- Rodriguez-Concepcion, M., Avalos, J., Bonet, M. L., Boronat, A., Gomez-Gomez, L., Hornero-Mendez, D., Limon, M. C., Meléndez-Martínez, A. J., Olmedilla-Alonso, B., Palou, A., Ribot, J., Rodrigo, M. J., Zacarias, L., & Zhu, C.
- Venue
- Progress in Lipid Research
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 70
- Pages
- 62-93
- ISSN
- 0163-7827 (ISSN-L)
- OpenAlex
- W2800549213
- Cited by
- 1,031
- References
- 31
- FWCI
- 51.15
- Type
- journal article
- Language
- en
- Open access
- green
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- Rodriguez-Concepcion, M., Avalos, J., Bonet, M. L., Boronat, A., Gomez-Gomez, L., Hornero-Mendez, D., Limon, M. C., Meléndez-Martínez, A. J., Olmedilla-Alonso, B., Palou, A., Ribot, J., Rodrigo, M. J., Zacarias, L., & Zhu, C. (2018). A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health. Progress in Lipid Research. https://doi.org/10.1016/j.plipres.2018.04.004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.