Kinetics of the hydrolytic degradation of poly(lactic acid)
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Although the two mechanisms operate simultaneously during hydrolysis, several studies have found that the chain-end scission is significantly faster than the random backbone cleavage.
“Although the two mechanisms operate simultaneously during hydrolysis, several studies have found that the chainend scission is significantly faster than the random backbone cleavage.424,426,427”
From Catalysis as an Enabling Science for Sustainable Polymers (2018) · cites this paper as [424]
At acidic pH the hydrolysis proceeds through a preferential scission of the end groups and spits out one lactic acid unit at a time, while the base catalyzed hydrolysis proceeds preferentially via a backbiting process from the OH chain end leading to the formation of lactide, which is eventually hydrolyzed to lactate.
“While at acidic pH the hydrolysis proceeds through a preferential scission of the end groups and spits out one lactic acid unit at a time, the base catalyzed hydrolysis proceeds preferentially via a backbiting process from the OH chain end leading to the formation of lactide, which is eventually hydrolyzed to lactate.”
From Catalysis as an Enabling Science for Sustainable Polymers (2018) · cites this paper as [424]
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Self-citation
- Authors
- Codari, F., Lazzari, S., Soos, M., Storti, G., Morbidelli, M., & Moscatelli, D.
- Affiliations
- ETH Zurich (CH)
- Politecnico di Milano (IT)
- Corresponding author
- Moscatelli, D.
- Venue
- Polymer Degradation and Stability
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 97
- Issue
- 11
- Pages
- 2460-2466
- ISSN
- 0141-3910 (ISSN-L)
- OpenAlex
- W1987117221
- Cited by
- 184
- References
- 32
- Citations by year
- 2026: 24 · 2025: 21 · 2024: 12 · 2023: 11 · 2022: 17 · 2021: 17 · 2020: 18 · 2019: 10 · 2018: 12 · 2017: 10 · 2016: 12 · 2015: 3 · 2014: 12 · 2013: 5
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Polymer Degradation and Stability (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Materials Science › Materials Chemistry › Thermal and Kinetic Analysis
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer Science and PVC
- Keywords
- polylactic acid, hydrolytic degradation, hydrolysis kinetics, kinetic model, activation energy, steric effects, crystallinity, water diffusion
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