Cited by 28Schizophrenia research and treatmentMental Health and PsychiatryBipolar Disorder and Treatment

The burden of depressive symptoms in people with schizophrenia

Conley, Robert R.·2009·Psychiatric Clinics of North America

Abstract

People with schizophrenia and concurrent depressive symptoms have poorer long-term functional outcomes compared with the nondepressed. Their poorer quality of life, greater use of mental health services, and higher risk of involvement with law enforcement agencies underscore a need for special treatment interventions. Treatment of the nonpsychotic dimensions of schizophrenia is a critical part of recovery. In a 3-year study, the depressed cohort was significantly more likely than the nondepressed to use relapse-related mental health services (emergency psychiatric services, sessions with psychiatrists); to be a safety concern (violent, arrested, victimized, or suicidal); to have greater substance-related problems; and to report poorer life satisfaction, quality of life, mental functioning, family relationships, and medication adherence. Furthermore, changes in depressed status were associated with changes in functional outcomes.

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Crossref · 10.1016/j.psc.2009.09.001

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Authors
Conley, R. R.
Affiliations
Eli Lilly (United States) (US)
Corresponding author
Conley, Robert R.
Venue
Psychiatric Clinics of North America
Publisher
Elsevier BV
Published
2009-12
Volume
32
Issue
4
Pages
853-861
ISSN
0193-953X (ISSN-L)
OpenAlex
W2080653269
Cited by
28
References
62
Citations by year
2023: 1 · 2022: 2 · 2020: 3 · 2019: 2 · 2018: 2 · 2016: 4 · 2015: 2 · 2014: 2 · 2013: 5 · 2012: 3
FWCI
1.03
Type
journal article
Language
en
Open access
closed
Locations
  • Psychiatric Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
Funders
Eli Lilly and Company
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
schizophrenia, depressive symptoms, comorbid depression, functional outcome, quality of life, mental health service utilization, relapse, violence, arrests, substance use, medication adherence, life satisfaction, family relationships, psychological functioning
MeSH terms
Antidepressive Agents, Clinical Protocols, Depression, Humans, Schizophrenia, Schizophrenic Psychology, Antipsychotic Agents, Cognitive Behavioral Therapy, Treatment Outcome, Cost of Illness

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