The burden of depressive symptoms in people with schizophrenia
Abstract
People with schizophrenia and concurrent depressive symptoms have poorer long-term functional outcomes compared with the nondepressed. Their poorer quality of life, greater use of mental health services, and higher risk of involvement with law enforcement agencies underscore a need for special treatment interventions. Treatment of the nonpsychotic dimensions of schizophrenia is a critical part of recovery. In a 3-year study, the depressed cohort was significantly more likely than the nondepressed to use relapse-related mental health services (emergency psychiatric services, sessions with psychiatrists); to be a safety concern (violent, arrested, victimized, or suicidal); to have greater substance-related problems; and to report poorer life satisfaction, quality of life, mental functioning, family relationships, and medication adherence. Furthermore, changes in depressed status were associated with changes in functional outcomes.
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Depression is associated with poorer adherence to treatment in individuals with psychosis and schizophrenia.
“poorer adherence to treatment (Conley, 2009)”
From A parallel group randomised open blinded evaluation of A cceptance and Commitment Therapy for d epression a fter p sychosis: Pilot t rial outcomes (ADAPT) (2017) · cites this paper as Conley, 2009
Depression has been associated with poorer adherence to treatment.
“Depression has been associated with poorer adherence to treatment (Conley, 2009)”
From A parallel group randomised open blinded evaluation of A cceptance and Commitment Therapy for d epression a fter p sychosis: Pilot t rial outcomes (ADAPT) (2017) · cites this paper as Conley, 2009
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- Authors
- Conley, R. R.
- Affiliations
- Eli Lilly (United States) (US)
- Corresponding author
- Conley, Robert R.
- Venue
- Psychiatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2009-12
- Volume
- 32
- Issue
- 4
- Pages
- 853-861
- ISSN
- 0193-953X (ISSN-L)
- OpenAlex
- W2080653269
- Cited by
- 28
- References
- 62
- Citations by year
- 2023: 1 · 2022: 2 · 2020: 3 · 2019: 2 · 2018: 2 · 2016: 4 · 2015: 2 · 2014: 2 · 2013: 5 · 2012: 3
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eli Lilly and Company
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Keywords
- schizophrenia, depressive symptoms, comorbid depression, functional outcome, quality of life, mental health service utilization, relapse, violence, arrests, substance use, medication adherence, life satisfaction, family relationships, psychological functioning
- MeSH terms
- Antidepressive Agents, Clinical Protocols, Depression, Humans, Schizophrenia, Schizophrenic Psychology, Antipsychotic Agents, Cognitive Behavioral Therapy, Treatment Outcome, Cost of Illness
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