A parallel group randomised open blinded evaluation of Acceptance and Commitment Therapy for Depression After Psychosis: A Pilot Trial Protocol (ADAPT)
Abstract
Background: Depression is one of the major contributors to poorer quality of life among individuals with psychosis and schizophrenia.Aims: This study protocol was designed as a pilot trial to determine the parameters of a larger, definitive pragmatic multi-centre randomised controlled trial of Acceptance and Commitment Therapy for depression after psychosis (ACTdp) for individuals with a diagnosis of schizophrenia who also meet diagnostic criteria for major depression.Methods: The study protocol was registered before initiating recruitment and was designed as a Parallel-group Randomised Open Blinded Evaluation (PROBE) comparing ACTdp plus standard care (SC) or SC alone. Participants were required to meet DSM-IV-TR criteria for schizophrenia and major depression (confirmed by Structured Clinical Interview for DSM/SCID-I & Calgary Depression Scale for Schizophrenia; score > 7). Blinded follow-ups are undertaken at 5 months (end of treatment) and at 10 months (5 months post treatment).Implications: The pilot aims to establish the basis for a larger-scale multi-centre randomised controlled trial of ACTdp. The most important study outcomes that will provide the basis of informing progression to a full trial are identified a priori as Population, Intervention, Control and Outcomes (PICO).
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The protocol was published before treatment codes were broken and data were analysed.
“The protocol was published before treatment codes were broken and data were analysed (Gumley et al., 2015).”
From A parallel group randomised open blinded evaluation of A cceptance and Commitment Therapy for d epression a fter p sychosis: Pilot t rial outcomes (ADAPT) (2017) · cites this paper as Gumley et al., 2015
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- Authors
- Gumley, A., White, R., Briggs, A., Ford, I., Barry, S., Stewart, C., Beedie, S., Clarke, C., MacLeod, R., Lidstone, E., Nam, J., & McLeod, H.
- Affiliations
- University of Glasgow (GB)
- NHS Greater Glasgow and Clyde (GB)
- Corresponding author
- Gumley, Andrew
- ORCID
- Venue
- Psychosis
- Publisher
- Informa UK Limited
- Published
- 2015-10-28
- Volume
- 8
- Issue
- 2
- Pages
- 143-155
- ISSN
- 1752-2439 (ISSN-L)
- 1752-2447
- OpenAlex
- W4253069106
- Semantic Scholar
- 324433bb68ad7c6c383bdb1873220550f694c44b
- Cited by
- 2
- References
- 33
- Citations by year
- 2021: 1 · 2016: 1
- FWCI
- 0.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychosis (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
- Strathprints: The University of Strathclyde institutional repository (University of Strathclyde) (submittedVersion)
- Funders
- Chief Scientist Office (CZH/4/743)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- acceptance and commitment therapy, schizophrenia, major depressive disorder, treatment-resistant depression, quality of life, pilot trial
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