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Reliability, validity and ability to detect change of the Personal and Social Performance scale in patients with stable schizophrenia
Abstract
This report describes the measurement properties of the Personal and Social Performance scale (PSP), a clinician-reported measure of severity of personal and social dysfunction, in an outpatient population with stabilized schizophrenia. Pooled data from two similar antipsychotic clinical studies were analyzed (n=411). The PSP showed good test-retest reliability (intraclass correlation coefficient=0.79). The PSP was more highly correlated with the Strauss-Carpenter Level of Function, an instrument measuring a similar construct, than the Positive and Negative Syndrome Scale, an instrument measuring a different construct. There was a statistically significant difference between mean PSP scores in subjects grouped by their severity rating on the Clinical Global Impression-Severity (CGI-S) (mild or less versus at least moderate), indicating the ability to discriminate between known groups. Effect sizes for mean change in the PSP based on 1-category improvement (0.72) or worsening (-0.88) versus no change in the CGI-S were moderate to large, demonstrating the ability to detect change. Estimates of between-group minimum important difference suggest that a 7-point improvement in the PSP may be clinically meaningful in a clinical trial setting. Initial reliability and validity assessments suggest the PSP may be a useful measure of social functioning in patients with stable schizophrenia.
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“The PSP showed good (> 0.80) interrater reliability and test–retest reliability [33, 34].”
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“Good test–retest reliability (ICC = .79) and validity assessments suggest that the PSP is valid for measuring social functioning.40”
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“76) (Kawata and Revicki, 2008) and reliability and validity of the measure has been demonstrated (Nasrallah et al., 2008).”
BackgroundNasrallah, H. A., Gopal, S., Gassmann-Mayer, C., Quiroz, J. A., Lim, P., Eerdekens, M., Yuen, E., & Hough, D. W. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.79 · Cited by 169
Self-citation
Metadata
- Authors
- Nasrallah, H., Morosini, P., & Gagnon, D. D.
- Affiliations
- University of Cincinnati (US)
- Istituto Superiore di Sanità (IT)
- Corresponding author
- Nasrallah, Henry
- ORCID
- Nasrallah, Henry
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2008-11
- Volume
- 161
- Issue
- 2
- Pages
- 213-224
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2100441519
- Cited by
- 243
- References
- 37
- Citations by year
- 2026: 17 · 2025: 17 · 2024: 16 · 2023: 18 · 2022: 18 · 2021: 18 · 2020: 20 · 2019: 16 · 2018: 10 · 2017: 16 · 2016: 21 · 2015: 8 · 2014: 12 · 2013: 10 · 2012: 7
- FWCI
- 3.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Johnson and Johnson
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Keywords
- Personal and Social Performance Scale, schizophrenia, social functioning, personal functioning, functional outcome assessment, test-retest reliability, construct validity, minimal clinically important difference, Clinical Global Impression Scale, antipsychotic drugs
- MeSH terms
- Adult, Ambulatory Care, Female, Humans, Male, Psychiatric Status Rating Scales, Psychometrics, Quality of Life, Surveys and Questionnaires, Schizophrenia, Schizophrenic Psychology, Social Adjustment, Antipsychotic Agents, Reproducibility of Results, Outcome Assessment, Health Care, Risperidone, Diagnostic and Statistical Manual of Mental Disorders
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