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Reliability, validity and ability to detect change of the Personal and Social Performance scale in patients with stable schizophrenia
Abstract
This report describes the measurement properties of the Personal and Social Performance scale (PSP), a clinician-reported measure of severity of personal and social dysfunction, in an outpatient population with stabilized schizophrenia. Pooled data from two similar antipsychotic clinical studies were analyzed (n=411). The PSP showed good test-retest reliability (intraclass correlation coefficient=0.79). The PSP was more highly correlated with the Strauss-Carpenter Level of Function, an instrument measuring a similar construct, than the Positive and Negative Syndrome Scale, an instrument measuring a different construct. There was a statistically significant difference between mean PSP scores in subjects grouped by their severity rating on the Clinical Global Impression-Severity (CGI-S) (mild or less versus at least moderate), indicating the ability to discriminate between known groups. Effect sizes for mean change in the PSP based on 1-category improvement (0.72) or worsening (-0.88) versus no change in the CGI-S were moderate to large, demonstrating the ability to detect change. Estimates of between-group minimum important difference suggest that a 7-point improvement in the PSP may be clinically meaningful in a clinical trial setting. Initial reliability and validity assessments suggest the PSP may be a useful measure of social functioning in patients with stable schizophrenia.
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“The PSP showed good (> 0.80) interrater reliability and test–retest reliability [33, 34].”
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“Good test–retest reliability (ICC = .79) and validity assessments suggest that the PSP is valid for measuring social functioning.40”
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Psychometric properties of the Questionnaire about the Process of Recovery (QPR)
Law, H., Neil, S. T., Dunn, G., & Morrison, A. P. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.04.011 · Cited by 172
“76) (Kawata and Revicki, 2008) and reliability and validity of the measure has been demonstrated (Nasrallah et al., 2008).”
BackgroundNasrallah, H. A., Gopal, S., Gassmann-Mayer, C., Quiroz, J. A., Lim, P., Eerdekens, M., Yuen, E., & Hough, D. W. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.79 · Cited by 169
Self-citationMetacognitive reflection and insight therapy (MERIT) for patients with schizophrenia
de Jong, S., van Donkersgoed, R. J. M., Timmerman, M. E., Rot, M. A. H., Wunderink, L., Arends, J., van der Gaag, M., Aleman, A., Lysaker, P. H., & Pijnenborg, G. H. M. (2018) · Psychological Medicine · doi:10.1017/s0033291718000855 · Cited by 160
“Personal and Social Performance Scale (PSP; Nasrallah et al. 2008).”
BackgroundGalderisi, S., Rucci, P., Mucci, A., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Bellomo, A., Bozzatello, P., et al. (2020) · World Psychiatry · doi:10.1002/wps.20700 · Cited by 148
Alvarez‐Jimenez, M., Koval, P., Schmaal, L., Bendall, S., O'Sullivan, S., Cagliarini, D., D'Alfonso, S., Rice, S., Valentine, L., Penn, D. L., et al. (2021) · World Psychiatry · doi:10.1002/wps.20858 · Cited by 130
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Self-citationFleischhacker, W., Galderisi, S., Laszlovszky, I., Szatmári, B., Barabássy, Á., Acsai, K., Szalai, E., Harsányi, J., Earley, W. R., Patel, M., et al. (2019) · European Psychiatry · doi:10.1016/j.eurpsy.2019.01.015 · Cited by 115
“Of interest, our post hoc analyses found significant differences at week 26 in favor of cariprazine versus risperidone on PANSS-derived Expressive Deficits and Avolition/Asociality factors, which both supports prospective PANSS-FSNS and PSP results, and suggests that cariprazine has broad-spectrum pharmacological prop…”
BackgroundInfluentialTzimos, A., Самохвалов, В. П., Kramer, M. L., Ford, L., Gassmann-Mayer, C., Lim, P., & Eerdekens, M. (2007) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31815a3e7a · Cited by 104
The Chinese version of the Personal and Social Performance Scale (PSP): Validity and reliability
Si, T., Shu, L., Su, Y., Chenghua, T., Yan, J., Cheng, J., Li, X., Qi, L., Ma, Y., Weihua, Z., et al. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2010.05.001 · Cited by 92
The Impact of Newer Atypical Antipsychotics on Patient-Reported Outcomes in Schizophrenia
Awad, A. G., & Voruganti, L. N. P. (2013) · CNS Drugs · doi:10.1007/s40263-013-0070-1 · Cited by 86
“[37], USA, industry funded, ARI 13 weeks randomized, pc study of ARI assessed reliability, validity and ability of PSP to detect change in social functioning PSP: no differences between ARI and PL.”
BackgroundFu, D., Turkoz, I., Simonson, R. B., Walling, D. P., Schooler, N. R., Lindenmayer, J., Canuso, C. M., & Alphs, L. D. (2014) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.14m09416 · Cited by 86
Antipsychotic Response Worsens With Postmenopausal Duration in Women With Schizophrenia
González-Rodríguez, A., Catalán, R., Penadés, R., Ruíz, V., Torra, M., Seeman, M. V., & Bernardo, M. (2016) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000571 · Cited by 77
“The PSP scale is a valid and reliable instrument for assessing the personal and social functioning in patients with schizophrenia.(28) It consists of the following 4 subdimensions or domains: self-care, socially useful activities (eg, work and study), personal and social relationships, and disturbing and aggressive be…”
MethodLaszlovszky, I., Barabássy, Á., & Németh, G. (2021) · Advances in Therapy · doi:10.1007/s12325-021-01797-5 · Cited by 78
Garcia-Portilla, M. P., Saiz, P. A., Bousoño, M., Bascaran, M. T., Guzmán-Quilo, C., & Bobes, J. (2011) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.rpsm.2010.11.003 · Cited by 75
Mancuso, S. G., Morgan, V. A., Mitchell, P. B., Berk, M., Young, A. H., & Castle, D. J. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.09.035 · Cited by 70
“, 2000) used in the present study is considered a reliable and valid measure of psychosocial functioning in SCZ (Nasrallah et al., 2008; Patrick et al., 2009).”
BackgroundMethodAlvarez-Jimenez, M., Bendall, S., Koval, P., Rice, S., Cagliarini, D., Valentine, L., D’Alfonso, S., Miles, C., Russon, P., Penn, D. L., et al. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-024104 · Cited by 69
Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia
McQueen, G., Sendt, K.-V., Gillespie, A. L., Avila, A., Lally, J., Vallianatou, K., Chang, N., Ferreira, D., Borgan, F., Howes, O. D., et al. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa156 · Cited by 74
Conen, S., Gregory, C. J., Hinz, R., Smallman, R. P., Zuelli, F. M. D. G. C., Deakin, J. F. W., & Talbot, P. S. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0829-y · Cited by 67
Childhood adversity and social functioning in psychosis: Exploring clinical and cognitive mediators
Palmier‐Claus, J. E., Berry, K., Darrell-Berry, H., Emsley, R., Parker, S., Drake, R., & Bucci, S. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.02.004 · Cited by 63
“The PSP has adequate reliability and validity in individuals with non-affective psychosis (Nasrallah et al., 2008; Patrick et al., 2009).”
BackgroundRossi, A., Amore, M., Galderisi, S., Rocca, P., Bertolino, A., Aguglia, E., Amodeo, G., Bellomo, A., Bucci, P., Buzzanca, A., et al. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.04.040 · Cited by 59
“(c) Psychosocial functioning was measured using the Personal and Social Performance (PSP) scale (Morosini et al., 2000; Nasrallah et al., 2008; Patrick et al., 2009).”
MethodPractical Implications of Metacognitively Oriented Psychotherapy in Psychosis
de Jong, S., van Donkersgoed, R. J. M., Aleman, A., van der Gaag, M., Wunderink, L., Arends, J., Lysaker, P. H., & Pijnenborg, G. H. M. (2016) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000564 · Cited by 55
de Bont, P. A. J. M., van den Berg, D. P. G., van der Vleugel, B. M., de Roos, C., Mulder, C. L., Becker, E. S., de Jongh, A., van der Gaag, M., & van Minnen, A. (2013) · Trials · doi:10.1186/1745-6215-14-151 · Cited by 52
Forbes, A., Hobart, M., Ouyang, J., Shi, L., Pfister, S., & Hakala, M. (2018) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyy002 · Cited by 52
“This is above the threshold for potentially clinically meaningful response in stabilized patients with schizophrenia (an increase of 4–7 points; Nasrallah et al., 2008) and close to functional remission (a total score of >70 points; Pinna et al.”
BackgroundGarcía‐Portilla, M. P., Sáiz, P. A., Bousoño, M., Bascarán, T., Guzmán-Quilo, C., & Bobes, J. (2011) · Revista de Psiquiatría y Salud Mental (English Edition) · doi:10.1016/s2173-5050(11)70003-6 · Cited by 51
Huntjens, A., van den Bosch, L. M. C. W., Sizoo, B., Kerkhof, A., Huibers, M. J. H., & van der Gaag, M. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02531-1 · Cited by 50
Ussorio, D., Giusti, L., Wittekind, C. E., Bianchini, V., Malavolta, M., Pollice, R., Casacchia, M., & Roncone, R. (2016) · Psychology and Psychotherapy: Theory, Research and Practice · doi:10.1111/papt.12059 · Cited by 51
Glenthøj, L. B., Fagerlund, B., Randers, L., Hjorthøj, C. R., Wenneberg, C., Krakauer, K., Vosgerau, A., Gluud, C. N., Medalia, A. A., Roberts, D. L., et al. (2015) · Trials · doi:10.1186/s13063-014-0542-8 · Cited by 47
“With 63 participants in each group, and assuming a pooled standard deviation of 10 points [72,78-81], we will have more than 97% power to detect a difference of 7 points between the groups, which would be considered the minimal clinically relevant difference on this scale [82].”
BackgroundInternet gaming as a coping method among schizophrenic patients facing psychological distress
Chang, Y.-H., Chang, K., Hou, W., Lin, C., & Griffiths, M. D. (2020) · Journal of Behavioral Addictions · doi:10.1556/2006.2020.00081 · Cited by 46
Reliability and validity of the Personal and Social Performance scale in patients with schizophrenia
Nafees, B., de Jonge, P. V. H., Stull, D. E., Pascoe, K. C., Price, M. J., Clarke, A. Y., & Turkington, D. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.06.013 · Cited by 45
“In addition, the current evidence agrees with findings in Nasrallah et al. (2008) whereby the PSP discriminated between known groups (p=0.0001).”
BackgroundMethodResultInfluentialParola, A., Simonsen, A., Lin, J. M., Zhou, Y., Wang, H., Ubukata, S., Koelkebeck, K., Bliksted, V., & Fusaroli, R. (2022) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac128 · Cited by 43
Rossi, A., Galderisi, S., Rocca, P., Bertolino, A., Mucci, A., Rucci, P., Gibertoni, D., Aguglia, E., Amore, M., Andriola, I., et al. (2016) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-016-0710-9 · Cited by 44
“The total score is usually divided into three levels: 71–100 (mild or no functioning difficulties); 31–70 (varying degrees of difficulties); and 0–30 (functioning so poor that the patient needs intensive support and supervision) [5, 28].”
BackgroundMethodBöge, K., Hahne, I., Bergmann, N., Wingenfeld, K., Zierhut, M., Thomas, N., Ta, T. M. T., Bajbouj, M., & Hahn, E. (2021) · Schizophrenia Research · doi:10.1016/j.schres.2020.12.008 · Cited by 44
Wu, B., Lin, C.-H. S., Tseng, H.-F., Liu, W.-M., Chen, W.-C., Huang, L.-S., Sun, H., Chiang, S., & Lee, S.-M. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.01.036 · Cited by 42
“Nonetheless, consistent with some studies (Nasrallah et al., 2008; Patrick et al., 2009), the moderate correlation between the changes in the PANSS and the TMV-PSP global score suggest that the TMV-PSP is an appropriate instrument to detect changes in schizophrenic symptoms.”
Edgar, C. J., Blaettler, T., Bugarski‐Kirola, D., Scouiller, S. L., Garibaldi, G. M., & Marder, S. R. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.04.009 · Cited by 40
“For the PSP, minimum important difference (MID) and responder threshold values have been established for stable patients with schizophrenia (Nasrallah et al., 2008).”
BackgroundJensen, S. B., Dalum, H. S., Korsbek, L., Hjorthøj, C. R., Mikkelsen, J. H., Thomsen, K., Kistrup, K. R., Olander, M., Lindschou, J., Mueser, K. T., et al. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2048-0 · Cited by 40
Needs, Perceived Support, and Hospital Readmissions in Patients with Severe Mental Illness
Parra, J. G., Moreno‐Küstner, B., Rivas, F., Alba-Vallejo, M., Hernández-Pedrosa, J., & Mayoral, F. (2017) · Community Mental Health Journal · doi:10.1007/s10597-017-0095-x · Cited by 39
Giordano, G. M., Pezzella, P., Mucci, A., Austin, S. F., Erfurth, A., Glenthoj, B. Y., Hofer, A., Hubeňák, J., Libiger, J., Melle, I. S., et al. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1333711 · Cited by 45
Jelastopulu, E., Giourou, E., Μερεκούλιας, Γ., Mestousi, A., Moratis, E., & Alexopoulos, E. C. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-197 · Cited by 39
“PSP has been used successfully on patients with schizophrenia in the acute [18,19] and stable stage [17,20] revealing high reliability and validity.”
MethodResultBrand, B. A., de Boer, J. N., Marcelis, M. C., Grootens, K. P., Luykx, J. J., & Sommer, I. E. (2023) · Schizophrenia Bulletin · doi:10.1093/schbul/sbad058 · Cited by 36
“Secondary outcomes included depression (Beck’s Depression Inventory, BDI), 36 quality of life (EQ-5D-5L) 37 personal and social performance (PSP) 33 and thought and language disorder (TALD) 38 (Supplementary Material p. 3 and Supplementary Table 3).”
BackgroundGantriis, D. L., Thorup, A. A. E., Harder, S. K., Greve, A. N., Henriksen, M. T., Zahle, K. K., Stadsgaard, H., Ellersgaard, D., Burton, B. K., Christiani, C. J., et al. (2019) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13057 · Cited by 36
“Although levels of social functioning and intelligence were found to be relatively good in caregivers with BP compared to clinical samples of individuals with SZ or BP (37, 38), the quality of the home environment was in the study assessed to be equally low in the FHR-SZ and FHR-BP children living with an affected par…”
ResultMarder, S. R., Hakala, M., Josiassen, M. K., Zhang, P. G. Y., Ouyang, J., Weiller, E., Weiss, C., & Hobart, M. (2016) · Acta Neuropsychiatrica · doi:10.1017/neu.2016.57 · Cited by 35
“Previous research in schizophrenia has noted that the PSP is reliable for detecting functional improvements in schizophrenia and that an increase of at least 7 points in PSP total score can be considered clinically meaningful to patients in terms of their overall functional capacity (34).”
BackgroundEngel, L., Alvarez-Jimenez, M., Cagliarini, D., D’Alfonso, S., Faller, J., Valentine, L., Koval, P., Bendall, S., O’Sullivan, S., Rice, S., et al. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbad071 · Cited by 34
“26 The PSP is a reliable and validated tool and is recommended for measuring social functioning in psychosis.”
MethodEffects of paliperidone extended release on the symptoms and functioning of schizophrenia
Huang, M., Yang, T., Ten, P.-R., Su, P., Wu, B., Chan, C.-H., Lan, T., Liu, I., Chiu, W., Li, C., et al. (2012) · BMC Clinical Pharmacology · doi:10.1186/1472-6904-12-1 · Cited by 34
“, clinicians, family members, friends, caregivers) as well as patient self-assessment [20-23].”
BackgroundFavrod, J., Nguyen, A., Tronche, A.-M., Blanc, O., Dubreucq, J., Chéreau, I., Capdevielle, D., & Llorca, P. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00532 · Cited by 33
“Scores between 1 and 50 reflect marked to very severe difficulties in two or more domains, whereas scores ≤30 demonstrate such poor social function as to require intensive support or supervision (34).”
BackgroundOliva, F., Dalmotto, M., Pirfo, E., Furlan, P. M., & Picci, R. L. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0239-2 · Cited by 34
“The validity and reliability of the PSP have already been evaluated [44,45].”
BackgroundLong, M., Stansfeld, J. L., Davies, N., Crellin, N. E., & Moncrieff, J. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.02.011 · Cited by 33
Jeppesen, U. N., Due, A. S., Mariegaard, L. S., Pinkham, A. E., Vos, M., Veling, W., Nordentoft, M., & Glenthøj, L. B. (2022) · Trials · doi:10.1186/s13063-022-06614-0 · Cited by 35
“Abbreviations RCT : Randomized clinical trial; VR: Virtual reality; CBT: Cognitive behavioral therapy; VR-CBT: Virtual reality-based cognitive behavioral therapy; TAU : Treatment as usual; GPTS: Green Paranoid Thought Scale; SIAS: Social Interaction Anxiety Scale; PSP: Personal and Social Performance scale; SBQ: Safet…”
MethodPatrick, D. L., Burns, T., Morosini, P., Gagnon, D. D., Rothman, M., & Adriaenssen, I. (2010) · Clinical Therapeutics · doi:10.1016/j.clinthera.2010.02.003 · Cited by 32
Self-citationSmith, L. C., Mariegaard, L. S., Vernal, D. L., Christensen, A. G., Albert, N., Thomas, N., Hjorthøj, C. R., Glenthøj, L. B., & Nordentoft, M. (2022) · Trials · doi:10.1186/s13063-022-06683-1 · Cited by 36
“The Personal and Social Performance Scale (PSP) [32] is included as a secondary measure assessing patients’ social and daily functioning.”
BackgroundHirayasu, Y., Sato, S., Takahashi, H., Iida, S., Shuto, N., Yoshida, S., Funatogawa, T., Yamada, T., & Higuchi, T. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0778-9 · Cited by 32
Vitger, T., Hjorthøj, C. R., Austin, S. F., Petersen, L., Tønder, E. S., Nordentoft, M., & Korsbek, L. (2022) · Journal of Medical Internet Research · doi:10.2196/40292 · Cited by 31
“We used the Scale for the Assessment of Positive Symptoms (SAPS) [23], Scale for the Assessment of Negative Symptoms (SANS) [23], Global Assessment of Functioning (GAF) [24] and Personal and Social Performance Scale (PSP) [25].”
Siskind, D. J., Harris, M., Phillipou, A., Morgan, V. A., Waterreus, A. J., Galletly, C. A., Carr, V. J., Harvey, C. A., & Castle, D. J. (2016) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016000305 · Cited by 31
“The PSP has good internal consistency and construct validity (Nasrallah et al. 2008; Patrick et al. 2009).”
BackgroundBurgess, P. M., Harris, M., Coombs, T., & Pirkis, J. (2017) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867416688098 · Cited by 31
“Sensitivity to change The PSP has been shown to detect change alongside established instruments like the PANSS and the CGI-S (Garcia-Portilla et al., 2011; Jelastopulu et al., 2014; Nafees et al., 2012; Nasrallah et al., 2008; Patrick et al., 2009; Tianmei et al., 2011).”
BackgroundMethodInfluentialNicholl, D., Nasrallah, H. A., Nuamah, I. F., Akhras, K. S., Gagnon, D. D., & Gopal, S. (2010) · Current Medical Research and Opinion · doi:10.1185/03007991003798927 · Cited by 29
Self-citationChen, K., Lee, S., Chiang, H.-Y. A., Syu, Y.-C., Yu, X.-X., & Hsieh, C. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.08.026 · Cited by 32
“…Clinical Global Impression – Severity scale, CGI-S), who had fluctuations in symptom severity during the study (i.e., any variation in CGI-S scores between the 2 visits), and who had substance abuse or other neurological deficits, such as dementia and mental retardation (Nasrallah et al., 2008).”
BackgroundLim, M., Li, Z., Xie, H., Tan, B. L., & Lee, J. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2238-9 · Cited by 28
Stürup, A. E., Jensen, H., Dolmer, S., Birk, M., Albert, N., Nielsen, M., Hjorthøj, C. R., Eplov, L. F., Ebdrup, B. H., Mors, O. N., et al. (2017) · Trials · doi:10.1186/s13063-017-2172-4 · Cited by 31
“Social functioning measured with the PSP (Personal and Social Performance Scale [37]) and the GAF (Global Assessment of Function [38]) at 1-, 2- and 5-year follow-up 8.”
MethodCorrell, C. U., Cortese, S., Solmi, M., Boldrini, T., Demyttenaere, K., Domschke, K., Fusar‐Poli, P., Gorwood, P. A. P. M., Harvey, P. D., Keefe, R. S. E., et al. (2025) · World Psychiatry · doi:10.1002/wps.21338 · Cited by 33
“It has shown good reliability and validity 77 .”
InfluentialKim, S., Kim, S., Koh, M., Choi, G., Kim, J.-J., Paik, I., Kim, S., Choi, Y. S., Lee, Y. H., Suh, J., et al. (2021) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.20m13446 · Cited by 27
Dubreucq, J., Gabayet, F., Godin, O., André, M., Aouizerate, B., Capdevielle, D., Chéreau, I., Clauss, J. M. E., Coulon, N., d’Amato, T., et al. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab114 · Cited by 27
Stürup, A. E., Hjorthøj, C. R., Jensen, H., Melau, M., Davy, J. W., Nordentoft, M., & Albert, N. (2023) · Early Intervention in Psychiatry · doi:10.1111/eip.13389 · Cited by 27
“Furthermore, information was collected on the following psychiatric variables: Diagnoses of schizophrenia (F20) and alcohol or substance misuse (F1x.1 or F1x.2) (assessed with SCAN), duration of untreated psychosis (DUP) (measured with an adjusted version of the interview for the retrospective assessment of the onset…”
Schaub, D., Brüne, M., Bierhoff, H., & Juckel, G. (2012) · Psychopathology · doi:10.1159/000330260 · Cited by 26
Canuso, C. M., Bossie, C. A., Turkoz, I., & Alphs, L. D. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.05.021 · Cited by 25
Fleischhacker, W. W., Hobart, M., Ouyang, J., Forbes, A., Pfister, S., McQuade, R. D., Carson, W. H., Sanchez, R., Nyilas, M., & Weiller, E. (2016) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyw076 · Cited by 88
“PSP scores (changes measured in the maintenance phase only) showed improvements with brexpiprazole that were above the threshold for clinically meaningful response in stabilized patients with schizophrenia (an increase of 4–7 points) (Nasrallah et al., 2008).”
BackgroundImmersive virtual reality in the treatment of auditory hallucinations: A PRISMA scoping review
Smith, L. C., Mateos, A. C., Due, A. S., Bergström, J., Nordentoft, M., Clemmensen, L., & Glenthøj, L. B. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115834 · Cited by 24
“Future larger-scale studies need to address these aspects when reporting on outcomes to enable quality assessment of studies and inform implementation.”
BackgroundSmith, L. C., Vernal, D. L., Mariegaard, L. S., Christensen, A. G., Jansen, J. E., Schytte, G., Stokbro, L. A., Albert, N., Christensen, M. J., Thomas, N., et al. (2025) · The Lancet Psychiatry · doi:10.1016/s2215-0366(25)00161-0 · Cited by 26
Siafis, S., Brandt, L., McCutcheon, R. A., Gutwinski, S., Schneider‐Thoma, J., Bighelli, I., Kane, J. M., Arango, C., Kahn, R. S., Fleischhacker, W. W., et al. (2023) · The Lancet Psychiatry · doi:10.1016/s2215-0366(23)00364-4 · Cited by 29
Kim, H.-Y., Lee, H. W., Jung, S.-H., Kang, M.-H., Bae, J. N., Lee, J.-S., & Kim, C. E. (2014) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2014.12.2.128 · Cited by 24
Themes of unfulfilled agency and communion in life stories of patients with schizophrenia
Holm, T., Thomsen, D. K., & Bliksted, V. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.08.116 · Cited by 26
Towards a framework for treatment effectiveness in schizophrenia
Juckel, G., de Bartolomeis, A., Gorwood, P. A. P. M., Mosolov, S. N., Pani, L., Rossi, A., & Sanjuán, J. (2014) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s61672 · Cited by 23
Brown, B., Turkoz, I., Mancevski, B., & Mathews, M. (2019) · Early Intervention in Psychiatry · doi:10.1111/eip.12868 · Cited by 23
“A mean PSP change of ≥7 points is considered clinically meaningful (Nasrallah et al., 2008).”
BackgroundHsieh, P. C., Huang, H. Y., Wang, H. C., Liu, Y. C., Bai, Y. M., Chen, K. C., & Yang, Y. K. (2011) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0b013e318221447e · Cited by 23
“The reliability and validity of this scale have been approved in several studies in which the Positive and Negative Syndrome Scale was administered (Morosini et al., 2000; Nasrallah et al., 2008; Patrick et al., 2009).”
MethodLindenmayer, J., Fregenti, S., Kang, G., Ozog, V., Ljuri, I., Khan, A., Goldring, A., & McGurk, S. R. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.01.007 · Cited by 22
A bottom-up model of functional outcome in schizophrenia
Luo, H., Zhao, Y., Fan, F., Fan, H., Wang, Y., Qu, W., Wang, Z., Tan, Y., Zhang, X., & Tan, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-87172-4 · Cited by 21
Responsiveness of the Personal and Social Performance scale in patients with schizophrenia
Chiu, E., Hung, T.-M., Huang, C.-M., Lee, S., & Hsieh, C. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.11.053 · Cited by 21
“The PSP has shown sufficient convergent validity (Pearson’ r = 0.95 among the PSP and the SOFAS), and discriminative validity (e.g., discriminating different levels of severity) in patients with schizophrenia (Garcia-Portilla et al., 2011; Nasrallah et al., 2008).””
BackgroundInfluentialPaliperidone extended‐release tablets in patients with recently diagnosed schizophrenia
Canuso, C. M., Bossie, C. A., Amatniek, J. C., Turkoz, I., Pandina, G., & Cornblatt, B. A. (2010) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2010.00165.x · Cited by 21
Dubreucq, J., Gabayet, F., Ycart, B., Faraldo, M., Melis, F., Lucas, T., Arnaud, B., Bacconnier, M., Bakri, M., Cambier, G., et al. (2020) · European Psychiatry · doi:10.1192/j.eurpsy.2020.42 · Cited by 20
“PSP showed acceptable internal consistency (Cronbach ’ s alpha [CA]=0.76) [27], excellent inter-rater reliability (ICC=0.97) [28], and a satisfactory ability to detect changes [26].”
InfluentialWitte, M. M., Case, M. G., Schuh, K. J., & Ascher‐Svanum, H. (2012) · Current Medical Research and Opinion · doi:10.1185/03007995.2012.657300 · Cited by 20
Vitger, T., Austin, S. F., Petersen, L., Tønder, E. S., Nordentoft, M., & Korsbek, L. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2143-2 · Cited by 18
Zierhut, M. M., Bergmann, N., Hahne, I., Wohlthan, J., Kraft, J., Braun, A., Ta, T. M. T., Hellmann‐Regen, J., Ripke, S., Bajbouj, M., et al. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.01.014 · Cited by 21
Kwon, J. S., Kim, S. N., Han, J., Lee, S.-I., Chang, J. S., Choi, J., Lee, H., Cho, S. J., Jun, T., Lee, S., et al. (2015) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000093 · Cited by 19
“The following were assessed at the same time points as the MSQ: Treatment Satisfaction Questionnaire for Medication (TSQM) (Atkinson et al., 2004), PANSS, and Personal and Social Performance (PSP) scale (Nasrallah et al., 2008).”
BackgroundMethodMetacognitive Therapy Focused on Psychosocial Function in Psychosis
Dubreucq, J., Delorme, C., & Roure, R. (2016) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-016-9334-7 · Cited by 18
Bai, Y. M., Hsiao, C. Y., Chen, K. C., Huang, K., Lee, I. H., Hsu, J.-W., Chen, P. S., & Yang, Y. K. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.08.024 · Cited by 19
“The PSP scale offers an efficientmethod ofmonitoring both psychosocial functioning in the acute phase and continuing treatment of schizophrenia (Kawata and Revicki, 2008; Nasrallah et al., 2008; Patrick et al., 2009), and has been translated into different languages, including German (Juckel et al.”
InfluentialKim, S.-J., Jung, D.-U., Moon, J., Jeon, D.-W., Seo, Y.-S., Jung, S. S., Lee, Y.-C., Kim, J.-E., & Kim, Y.-S. (2020) · Schizophrenia Research Cognition · doi:10.1016/j.scog.2020.100192 · Cited by 18
“The PSP has demonstrated high validity and reliability for patients with schizophrenia (Nasrallah et al., 2008).”
BackgroundCanuso, C. M., Turkoz, I., Sheehan, J. J., & Bossie, C. A. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.05.025 · Cited by 18
“A population analysis of the PSP scale has suggested that a mean increase of ≥7 points indicates clinically meaningful functional improvement (Patrick et al., 2009; Nasrallah et al., 2008).”
Paliperidone Palmitate for Schizoaffective Disorder: A Review of the Clinical Evidence
Greenberg, W. M., & Citrome, L. (2015) · Neurological Therapeutics · doi:10.1007/s40120-015-0030-4 · Cited by 14
“Overall, paliperidone palmitate was superior to placebo in maintaining functioning measured by the PSP scale (P = 0.014, mixed-model repeated measures).”
InfluentialThe reliability of the Personal and Social Performance scale – informing its training and use
White, S. J., Dominise, C., Naik, D., & Killaspy, H. T. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.06.047 · Cited by 20
“Obtaining access to relevant information can therefore pose a difficulty in its use (Nasrallah et al , 2008).”
BackgroundArnfred, B. T., Bang, P., Hjorthøj, C. R., Winding, C., Moeller, K. S., Hvenegaard, M., Agerskov, L., Gausbøl, U. K., Soe, D., Wiborg, P., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-051147 · Cited by 21
Bucci, P., Giordano, G. M., Mucci, A., Rocca, P., Rossi, A., Bertolino, A., Aguglia, E., Altamura, C. A., Amore, M., Bellomo, A., et al. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2022.12.021 · Cited by 19
“…Level of Functioning Scale, SLOF (Mucci et al., 2014), a preliminary ROC analysis was carried out on the sample ( N = 921) of the baseline study (Galderisi et al., 2014) using a Personal and Social Performance (PSP) score ≥ 71 as the gold standard for functional recovery (Nasrallah et al., 2008).”
Fu, D., Turkoz, I., Walling, D. P., Lindenmayer, J., Schooler, N. R., & Alphs, L. D. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.04.004 · Cited by 17
“…bathing/showering, washing hair, brushing teeth, changing clothes, taking medication, or eating), and (D) disturbing/aggressive behavior (i.e., speaking too loudly, cursing, verbal threats, breaking or throwing objects, fighting, and threatening to harm self or others) (Nasrallah et al., 2008).”
InfluentialRofail, D., Regnault, A., Scouiller, S. L., Lambert, J., & Zarit, S. H. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0951-1 · Cited by 17
“The PSP is a single-item clinician-rated 100-point scale enabling the determination of small changes in levels of functioning [18].”
Backgroundvan den Berg, D. P. G., van der Vleugel, B. M., de Bont, P. A. J. M., Thijssen, G., de Roos, C., de Kleine, R. A., Kraan, T. C., Ising, H. K., de Jongh, A., van Minnen, A., et al. (2016) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v7.31712 · Cited by 17
Christensen, T. N., Nielsen, I. G., Stenager, E. N., Morthorst, B. R., Lindschou, J., Nordentoft, M., & Eplov, L. F. (2015) · Trials · doi:10.1186/s13063-015-0792-0 · Cited by 20
“[46] (2008) (No IPS studies use PSP scale.”
Add-on of aripiprazole improves outcome in clozapine-resistant schizophrenia
Risio, A. D., Pancheri, A., Simonetti, G., Giannarelli, D., Stefanutto, L., & Gentile, B. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.03.011 · Cited by 15
“…underscored how the addition of an antipsychotic combination with an integrated non-pharmacological rehabilitation treatment resulted in enhancement of social competences by detecting subtle, but clinically meaningful changes even better than QLS (Nasrallah et al., 2008; Juckel and Morosini, 2008).”
Aberrant effective connectivity is associated with positive symptoms in first-episode schizophrenia
Dietz, M. J., Zhou, Y., Veddum, L., Frith, C., & Bliksted, V. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102444 · Cited by 15
“Visual fixation periods were not modelled and hence constituted an implicit SANS: Scale for Assessment of Negative Symptoms SAPS: Scale for Assessment of Positive Symptoms PSP: Personal and Social Performance scale GAF-F: Global Assessment of Functioning – level of social functioning WAIS-III: Wechsler Adult Intellige…”
Alphs, L. D., Brown, B., Turkoz, I., Baker, P. C., Fu, D., & Nuechterlein, K. H. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.02.019 · Cited by 16
“Personal and social functioning and overall illness severity were assessed via the PSP scale (Morosini et al., 2000; Nasrallah et al., 2008) and the Clinical Global Impression-Severity (CGI-S) scale (Guy, 1976), respectively.”
Menezes, A. K. P. M., Macedo, G., Mattos, P., Júnior, A. R. D. S., & Louzã, M. R. (2012) · Jornal Brasileiro de Psiquiatria · doi:10.1590/s0047-20852012000300009 · Cited by 15
Metadata
- Authors
- Nasrallah, H., Morosini, P., & Gagnon, D. D.
- Affiliations
- University of Cincinnati (US)
- Istituto Superiore di Sanità (IT)
- Corresponding author
- Nasrallah, Henry
- ORCID
- Nasrallah, Henry
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2008-11
- Volume
- 161
- Issue
- 2
- Pages
- 213-224
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2100441519
- Cited by
- 243
- References
- 37
- Citations by year
- 2026: 17 · 2025: 17 · 2024: 16 · 2023: 18 · 2022: 18 · 2021: 18 · 2020: 20 · 2019: 16 · 2018: 10 · 2017: 16 · 2016: 21 · 2015: 8 · 2014: 12 · 2013: 10 · 2012: 7
- FWCI
- 3.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Johnson and Johnson
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Keywords
- Personal and Social Performance Scale, schizophrenia, social functioning, personal functioning, functional outcome assessment, test-retest reliability, construct validity, minimal clinically important difference, Clinical Global Impression Scale, antipsychotic drugs
- MeSH terms
- Adult, Ambulatory Care, Female, Humans, Male, Psychiatric Status Rating Scales, Psychometrics, Quality of Life, Surveys and Questionnaires, Schizophrenia, Schizophrenic Psychology, Social Adjustment, Antipsychotic Agents, Reproducibility of Results, Outcome Assessment, Health Care, Risperidone, Diagnostic and Statistical Manual of Mental Disorders
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