Cited by 22Schizophrenia research and treatmentPsychiatric care and mental health servicesMental Health and Psychiatry

An examination of neurocognition and symptoms as predictors of post-hospital community tenure in treatment resistant schizophrenia

Ahmed, Anthony O., Murphy, Christopher F., Latoussakis, Vassilios, McGovern, Kelly E., English, Judith, Bloch, Andrew, Anthony, Donna T., Savitz, Adam J.·2016·Psychiatry Research

Abstract

Neurocognition and psychopathology are robust predictors of community functioning and relapse/rehospitalization in schizophrenia. Existing studies are however limited because they have ignored the most chronic, treatment-resistant patients. Moreover, the prediction of functional outcomes has yet to be extended to the duration of community tenure, an indicator of the capacity of chronically-hospitalized patients to gain traction in the community. The current study examined neurocognition and symptom severity at discharge as potential predictors of community tenure in chronically-hospitalized treatment-resistant patients. The study recruited 90 people with treatment-resistant schizophrenia who received services on an inpatient unit. Participants completed measures of psychopathology and neurocognition prior to discharge. Following discharge, participants were tracked at current residences six months and one year post-discharge to assess community tenure. The percentage of individuals who continued to live in the community at 12-month follow-up was 51%. Severe negative symptoms but not neurocognitive impairment or positive symptoms was a significant predictor of shorter post-hospital community tenure. Of the negative symptoms domain, anhedonia-asociality proved to be the most relevant predictor of community tenure in the sample. The capacity to elicit goal-directed behaviors in response to anticipated physical and social rewards may be an important treatment target for sustainin…

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Crossref · 10.1016/j.psychres.2016.01.001

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  • In treatment-resistant patients with schizophrenia, lower levels of anhedonia-asociality predict a longer time living in the community between admissions.

    “Conversely, in treatment-resistant patients with schizophrenia, lower levels of anhedonia–asociality predicted a longer time living in the community between admissions (48).”

    From A transdiagnostic perspective on social anhedonia (2019) · cites this paper as [48]

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Authors
Ahmed, A. O., Murphy, C. F., Latoussakis, V., McGovern, K. E., English, J., Bloch, A., Anthony, D. T., & Savitz, A. J.
Affiliations
Weill Cornell Medicine (US)
Corresponding author
Ahmed, Anthony O.
Venue
Psychiatry Research
Publisher
Elsevier BV
Published
2016-02
Volume
236
Pages
47-52
ISSN
0165-1781 (ISSN-L)
OpenAlex
W2231925678
Cited by
22
References
55
Citations by year
2025: 4 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 2
FWCI
2.37
Type
journal article
Language
en
Open access
closed
Locations
  • Psychiatry Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
Mental Health Initiative
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords
treatment-resistant schizophrenia, neurocognitive function, negative symptoms, communal land tenure, post-discharge outcomes, psychopathology, goal-directed behavior
MeSH terms
Adult, Cognition Disorders, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Schizophrenia, Schizophrenic Psychology, Social Behavior, Antipsychotic Agents

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