Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS

Green, Michael F.; Kern, Robert S.; Heaton, Robert K.

doi:10.1016/j.schres.2004.09.009

Cited by 1,422Schizophrenia research and treatmentMental Health and PsychiatryDementia and Cognitive Impairment Research

Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS

Green, Michael F., Kern, Robert S., Heaton, Robert K.·2004·Schizophrenia Research

DOI 10.1016/j.schres.2004.09.009

Open this paper in CoChat — free account

Abstract

It is generally accepted that cognitive deficits in schizophrenia are related to functional outcome. However, support for longitudinal relationships between cognition and functional outcome has not been as well documented. The current paper presents a review of 18 recently published longitudinal studies (minimum 6-month follow up) of the relationships between cognition and community outcome in schizophrenia. Results from these studies reveal considerable support for longitudinal associations between cognition and community outcome in schizophrenia. These studies demonstrate that cognitive assessment predict later functional outcome and provide a rationale for psychopharmacological interventions for cognitive deficits in schizophrenia. Although the relationships between cognition and community outcome are well-supported, it is clear that community functioning is also affected by a host of factors apart from cognition that are usually not considered in clinical trial studies (e.g., psychosocial rehabilitation and educational/vocational opportunities). In the second part of the paper, we consider intervening steps between cognitive performance measures and community outcome. These steps are apt to have important implications for clinical trials of cognition-enhancing agents in schizophrenia.

Integrity signals

Registry

Crossref · 10.1016/j.schres.2004.09.009

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A qualifier for cognitive symptoms is intended to provide more diagnostic and therapeutic attention to cognitive symptoms because these are linked to functional outcome.
“A qualifier for cognitive symptoms is intended to provide more diagnostic and therapeutic attention to cognitive symptoms as these are linked to functional outcome [27].”
From Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies (2020) · cites this paper as [27]

Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,406 · see citing works
What are the functional consequences of neurocognitive deficits in schizophrenia?
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.3.321 · Cited by 3,516 · see citing works
Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the ‘‘right stuff’’?
Green, M. F., Kern, R. S., Braff, D. L., & Mintz, J. (2000) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033430 · Cited by 2,999 · see citing works
Self-citation
Statistical Power Analysis for the Behavioral Sciences
(1977) · doi:10.1016/c2013-0-10517-x · Cited by 2,457 · see citing works
The Quality of Life Scale: An Instrument for Rating the Schizophrenic Deficit Syndrome
Heinrichs, D. W., Hanlon, T. E., & Carpenter, W. T. (1984) · Schizophrenia Bulletin · doi:10.1093/schbul/10.3.388 · Cited by 1,693 · see citing works
The Social Functioning Scale the Development and Validation of a New Scale of Social Adjustment for use in Family Intervention Programmes with Schizophrenic Patients
Birchwood, M., Smith, J., Cochrane, R., Wetton, S., & Copestake, S. (1990) · British Journal of Psychiatry · doi:10.1192/bjp.157.6.853 · Cited by 1,157 · see citing works
A quality of life interview for the chronically mentally ill
Lehman, A. F. (1988) · Evaluation and Program Planning · doi:10.1016/0149-7189(88)90033-x · Cited by 1,085 · see citing works
Approaching a consensus cognitive battery for clinical trials in schizophrenia: The NIMH-MATRICS conference to select cognitive domains and test criteria
Green, M. F., Nuechterlein, K. H., Gold, J. M., Barch, D. M., Cohen, J., Essock, S., Fenton, W. S., Frese, F., Goldberg, T. E., Heaton, R. K., et al. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.06.023 · Cited by 919 · see citing works
Self-citation
UCSD Performance-Based Skills Assessment: Development of a New Measure of Everyday Functioning for Severely Mentally Ill Adults
Patterson, T., Goldman, S., McKibbin, C. L., Hughs, T., & Jeste, D. V. (2001) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a006870 · Cited by 740 · see citing works
The impact of HIV-associated neuropsychological impairment on everyday functioning
Heaton, R. K., Marcotte, T. D., Mindt, M. R., Sadek, J. R., Moore, D. J., Bentley, H. A., McCutchan, J. A., REICKS, C., Grant, I., & THE HNRC GROUP (2004) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617704102130 · Cited by 726 · see citing works
Self-citation
Symptomatic and Functional Recovery From a First Episode of Schizophrenia or Schizoaffective Disorder
Robinson, D. G., Woerner, M. G., McMeniman, M., Mendelowitz, A., & Bilder, R. M. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.3.473 · Cited by 590 · see citing works
Should schizophrenia be treated as a neurocognitive disorder?
Green, M. F., & Nuechterlein, K. (1999) · Schizophrenia bulletin · doi:10.1093/oxfordjournals.schbul.a033380 · Cited by 447 · see citing works
Self-citation
Measurement and Treatment Research to Improve Cognition in Schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia
Marder, S. R., & Fenton, W. S. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2004.09.010 · Cited by 419 · see citing works
The Life Skills Profile: A Measure Assessing Function and Disability in Schizophrenia
Rosen, A., Hadži-Pavlović, D., & Parker, G. B. (1989) · Schizophrenia Bulletin · doi:10.1093/schbul/15.2.325 · Cited by 416 · see citing works
The Measurement of Social Behaviour in Psychiatric Patients: An Assessment of the Reliability and Validity of the SBS Schedule
Wykes, T., & Sturt, E. (1986) · The British Journal of Psychiatry · doi:10.1192/bjp.148.1.1 · Cited by 371 · see citing works
Neurocognitive and Social Functioning in Schizophrenia
Addington, J., & Addington, D. E. (1999) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033363 · Cited by 365 · see citing works
Use of neuropsychological tests to predict adult patients' everyday functioning.
Heaton, R. K., & Pendleton, M. G. (1981) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.49.6.807 · Cited by 311 · see citing works
Self-citation
The MATRICS initiative: developing a consensus cognitive battery for clinical trials
Green, M. F., & Nuechterlein, K. H. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2004.09.006 · Cited by 285 · see citing works
Self-citation
Cognitive Correlates of Job Tenure Among Patients With Severe Mental Illness
Gold, J. M., Goldberg, R. W., McNary, S. W., Dixon, L. B., & Lehman, A. F. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.8.1395 · Cited by 285 · see citing works
Colorado Springs, Colorado
Gamer, C. (1973) · The Musical Quarterly · doi:10.1093/mq/lix.3.462 · Cited by 283 · see citing works
Use of neuropsychological tests to predict adult patients' everyday functioning.
Heaton, R. K., & Pendleton, M. G. (1981) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.49.6.807 · Cited by 265 · see citing works
Self-citation
A new patient focused index for measuring quality of life in persons with severe and persistent mental illness
Becker, M. C., Diamond, R., & Sainfort, F. (1993) · Quality of Life Research · doi:10.1007/bf00434796 · Cited by 263 · see citing works
Neurocognitive and social functioning in schizophrenia: a 2.5 year follow-up study
Addington, J., & Addington, D. E. (2000) · Schizophrenia Research · doi:10.1016/s0920-9964(99)00160-7 · Cited by 253 · see citing works
A community ability scale for chronically mentally Ill consumers: Part I. Reliability and validity
Barker, S., Barron, N. M., McFarland, B. H., & Bigelow, D. A. (1994) · Community Mental Health Journal · doi:10.1007/bf02207489 · Cited by 250 · see citing works
Do Specific Neurocognitive Deficits Predict Specific Domains of Community Function in Schizophrenia?
Velligan, D. I., Bow-Thomas, C. C., Mahurin, R. K., Miller, A. L., & Halgunseth, L. C. (2000) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200008000-00007 · Cited by 248 · see citing works
Evaluation of social problem solving in schizophrenia.
Bellack, A. S., Sayers, M. D., Mueser, K. T., & Bennett, M. (1994) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.103.2.371 · Cited by 222 · see citing works
Neurocognitive function and outcome in first-episode schizophrenia: a 10-year follow-up of an epidemiological cohort
Stirling, J. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00014-8 · Cited by 218 · see citing works
Neurocognitive and social functioning in schizophrenia: A 2.5 year follow-up study
Addington, J., & Addington, D. E. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(97)82256-6 · Cited by 209 · see citing works
Social functioning and neurocognitive deficits in outpatients with schizophrenia: a 2-year follow-up
Dickerson, F. (1999) · Schizophrenia Research · doi:10.1016/s0920-9964(98)00134-0 · Cited by 184 · see citing works
Evaluation of social problem solving in schizophrenia.
Bellack, A. S., Sayers, M. D., Mueser, K. T., et al. (1994) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.103.2.371 · Cited by 172 · see citing works
Prolonged Untreated Illness Duration From Prodromal Onset Predicts Outcome in First Episode Psychoses
Keshavan, M. S., Haas, G. L., Miewald, J. M., Montrose, D. M., Reddy, R. D., Schooler, N. R., & Sweeney, J. A. (2003) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a007045 · Cited by 165 · see citing works
Work Rehabilitation in Schizophrenia: Does Cognitive Impairment Limit Improvement?
Bell, M. D., & BRYSON, G. J. (2001) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a006873 · Cited by 164 · see citing works
Symptoms, cognition, treatment adherence and functional outcome in first-episode psychosis
MALLA, A. K., Norman, R. M. G., Manchanda, R., & Townsend, L. A. (2002) · Psychological Medicine · doi:10.1017/s0033291702006050 · Cited by 156 · see citing works
Symptoms and Cognition as Predictors of Community Functioning: A Prospective Analysis
Norman, R. M. G., MALLA, A. K., Cortese, L., Cheng, S. K. K., Diaz, K. M., McIntosh, E., McLean, T. S., Rickwood, A., & Voruganti, L. P. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.3.400 · Cited by 154 · see citing works
INITIAL AND FINAL WORK PERFORMANCE IN SCHIZOPHRENIA: COGNITIVE AND SYMPTOM PREDICTORS
BRYSON, G., & BELL, M. D. (2003) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000050937.06332.3c · Cited by 138 · see citing works
NIMH-MATRICS survey on assessment of neurocognition in schizophrenia
Kern, R. S., Green, M. F., Nuechterlein, K. H., & Deng, B.-H. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2004.09.004 · Cited by 124 · see citing works
Self-citation
REHAB: A New Assessment Instrument for Chronic Psychiatric Patients
Baker, R. D., & Hall, J. (1988) · Schizophrenia Bulletin · doi:10.1093/schbul/14.1.97 · Cited by 93 · see citing works
The impact of service characteristics on functional outcomes from community support programs for persons with schizophrenia: A growth curve analysis.
Brekke, J. S., Long, J. D., Nesbitt, N., & Sobel, E. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.65.3.464 · Cited by 92 · see citing works
Neurocognition and long-term prediction of quality of life in outpatients with severe and persistent mental illness
Fujii, D. E. M. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00122-1 · Cited by 91 · see citing works
Recovery from psychosis in schizophrenia and schizoaffective disorder: symptoms and neurocognitive rate-limiters for the development of social behavior skills
Smith, T. E., Hull, J. W., Huppert, J. D., & Silverstein, S. M. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00231-6 · Cited by 89 · see citing works
Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients
Kasckow, J., Twamley, E. W., Mulchahey, J. J., Carroll, B. T., Sabai, M., Strakowski, S. M., Patterson, T. L., & Jeste, D. V. (2001) · Psychiatry Research · doi:10.1016/s0165-1781(01)00260-8 · Cited by 83 · see citing works
Direct assessment of functional status in older patients with schizophrenia
Klapow, J. C., Evans, J. D., Patterson, T. L., Heaton, R. K., Koch, W. L., & Jeste, D. V. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.7.1022 · Cited by 81 · see citing works
Self-citation
Neurocognition and community outcome in schizophrenia: long-term predictive validity
Fujii, D. E. M., & Wylie, A. M. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00328-0 · Cited by 77 · see citing works
Basic neuropsychological dimensions in schizophrenia
Jaeger, J. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00052-5 · Cited by 75 · see citing works
Correlates of Change in Functional Status of Institutionalized Geriatric Schizophrenic Patients: Focus on Medical Comorbidity
Friedman, J. I., Harvey, P. D., McGurk, S. R., WHITE, L. E., Parrella, M. J., Raykov, T., Coleman, T. M., Adler, D. N., & Davis, K. L. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.8.1388 · Cited by 72 · see citing works
The impact of service characteristics on functional outcomes from community support programs for persons with schizophrenia: A growth curve analysis.
Brekke, J. S., Long, J. D., Nesbitt, N., et al. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.65.3.464 · Cited by 71 · see citing works
Nature and vocational significance of neuropsychological impairment associated with HIV infection
Heaton, R. K., Marcotte, T. D., White, D. A., et al. (1996) · The Clinical Neuropsychologist · doi:10.1080/13854049608406658 · Cited by 66 · see citing works
Self-citation
The Work Behavior Inventory: A scale for the assessment of work behavior for people with severe mental illness.
BRYSON, G. J., Bell, M. D., Lysaker, P. H., & Zito, W. (1997) · Psychiatric Rehabilitation Journal · Cited by 61 · see citing works
The work behavior inventory: A scale for the assessment of work behavior for clients with severe mental illness
BRYSON, G. J., Bel, M., Lysaker, P. H., & Zito, W. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(97)82631-x · Cited by 47 · see citing works
Learning (potential) and social functioning in schizophrenia
Woonings, F. M. J., Appelo, M. T., Kluiter, H., Slooff, C. J., & van den Bosch, R. J. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00163-9 · Cited by 44 · see citing works
A system for allocating mental health resources
Leff, H. S., Graves, S. C., Natkins, J., et al. (1985) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/bf00819235 · Cited by 18 · see citing works
Biosocial pathways to functional outcome in schizophrenia: A path analytic model
Brekke, J. S., Kay, D., Kee, K. R., & Green, M. F. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)81024-1 · Cited by 15 · see citing works
Self-citation
International Neuropsychological Society
McCartney, R. (2010) · Springer eBooks · doi:10.1007/978-0-387-79948-3_627 · Cited by 7 · see citing works

Flagged first, then by citations

Sorted by citations

The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity
Nuechterlein, K. H., Green, M. F., Kern, R. S., Baade, L. E., Barch, D. M., Cohen, J. D., Essock, S., Fenton, W. S., Frese, F. J., Gold, J. M., et al. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07010042 · Cited by 2,342 · see citing works
Self-citation
The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: A meta-analysis
Fett, A.-K. J., Viechtbauer, W., Dominguez, M.-D.-G., Penn, D. L., van Os, J., & Krabbendam, L. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.001 · Cited by 1,833 · see citing works
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
Millan, M. J., Agid, Y., Brüne, M., Bullmore, E. T., Carter, C. S., Clayton, N. S., Connor, R., Davis, S., Deakin, B., DeRubeis, R. J., et al. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3628 · Cited by 1,292 · see citing works
Nonsocial and social cognition in schizophrenia: current evidence and future directions
Green, M. F., Horan, W. P., & Lee, J. (2019) · World Psychiatry · doi:10.1002/wps.20624 · Cited by 612 · see citing works
Self-citation
The Dual-State Theory of Prefrontal Cortex Dopamine Function with Relevance to Catechol-O-Methyltransferase Genotypes and Schizophrenia
Durstewitz, D., & Seamans, J. K. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.05.015 · Cited by 586 · see citing works
The global cognitive impairment in schizophrenia: consistent over decades and around the world
Schaefer, J., Giangrande, E., Weinberger, D. R., & Dickinson, D. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.07.009 · Cited by 605 · see citing works
A Double-Blind, Randomized Study of Minocycline for the Treatment of Negative and Cognitive Symptoms in Early-Phase Schizophrenia
Levkovitz, Y., Mendlovich, S., Riwkes, S., Braw, Y., Levkovitch-Verbin, H., Gal, G., Fennig, S., Treves, I., & Kron, S. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04666yel · Cited by 387 · see citing works
Neuroprotective Effects of Cognitive Enhancement Therapy Against Gray Matter Loss in Early Schizophrenia: Results From a 2-Year Randomized Controlled Trial
Eack, S. M., Hogarty, G. E., Cho, R. Y., Prasad, K. M. R., Greenwald, D. P., Hogarty, S. S., & Keshavan, M. S. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.63 · Cited by 360 · see citing works
Neurocognitive predictors of work outcome in recent-onset schizophrenia.
Nuechterlein, K. H., Subotnik, K. L., Green, M. F., Ventura, J., Asarnow, R. F., Gitlin, M. J., Yee, C. M., Gretchen-Doorly, D., & Mintz, J. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr084 · Cited by 297 · see citing works
Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress
Hains, A. B., Vu, M. A. T., Maciejewski, P. K., van Dyck, C. H., Gottron, M., & Arnsten, A. F. T. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908563106 · Cited by 234 · see citing works
The Impact of Aerobic Exercise on Brain-Derived Neurotrophic Factor and Neurocognition in Individuals With Schizophrenia: A Single-Blind, Randomized Clinical Trial
Kimhy, D., Vakhrusheva, J., Bartels, M. N., Armstrong, H. F., Ballon, J. S., Khan, S., Chang, R. W., Hansen, M. C., Ayanruoh, L., Lister, A., et al. (2015) · Schizophrenia Bulletin · doi:10.1093/schbul/sbv022 · Cited by 207 · see citing works
Cognitive-behavioral therapy for medication-resistant psychosis: A meta-analytic review
Burns, A. M. N., Erickson, D. H., & Brenner, C. A. (2014) · Psychiatric Services · doi:10.1176/appi.ps.201300213 · Cited by 199 · see citing works
A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia
Buchanan, R. W., Keefe, R. S. E., Lieberman, J. A., Barch, D. M., Csernansky, J. G., Goff, D. C., Gold, J. M., Green, M. F., Jarskog, L. F., Javitt, D. C., et al. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.052 · Cited by 172 · see citing works
Self-citation
The family of sensorimotor gating disorders: Comorbidities or diagnostic overlaps?
Geyer, M. A. (2006) · Neurotoxicity Research · doi:10.1007/bf03033358 · Cited by 159 · see citing works
The FDA-NIMH-MATRICS Guidelines for clinical trial design of cognitive-enhancing drugs: what do we know 5 years later?
Buchanan, R. W., Keefe, R. S. E., Umbricht, D., Green, M. F., Laughren, T., & Marder, S. R. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbq038 · Cited by 154 · see citing works
Self-citation
Cognitive impairments in psychotic disorders: common mechanisms and measurement
Barch, D. M., & Sheffield, J. M. (2014) · World Psychiatry · doi:10.1002/wps.20145 · Cited by 154 · see citing works
The relationship between workplace spirituality, job satisfaction and organizational citizenship behaviors – an empirical study
Belwalkar, S., Vohra, V., & Pandey, A. (2018) · Social Responsibility Journal · doi:10.1108/srj-05-2016-0096 · Cited by 151 · see citing works
Can Repetitive Magnetic Stimulation Improve Cognition in Schizophrenia? Pilot Data from a Randomized Controlled Trial
Barr, M. S., Farzan, F., Rajji, T. K., Voineskos, A. N., Blumberger, D. M., Arenovich, T., Fitzgerald, P. B., & Daskalakis, Z. J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.08.020 · Cited by 144 · see citing works
Status of Psychotic Disorders in ICD-11
Gaebel, W. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs104 · Cited by 137 · see citing works
Drug targets for cognitive enhancement in neuropsychiatric disorders.
Wallace, T. L., Ballard, T. M., Pouzet, B., Riedel, W. J., & Wettstein, J. G. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.03.022 · Cited by 127 · see citing works
User-Centered Design of Learn to Quit, a Smoking Cessation Smartphone App for People With Serious Mental Illness
Vilardaga, R., Rizo, J., Zeng, E., Kientz, J. A., Ries, R., Otis, C., & Hernandez, K. (2018) · JMIR Serious Games · doi:10.2196/games.8881 · Cited by 90 · see citing works
Motivational Interviewing to Increase Cognitive Rehabilitation Adherence in Schizophrenia
Fiszdon, J. M., Kurtz, M. M., Choi, J., Bell, M. D., & Martino, S. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbv143 · Cited by 104 · see citing works
Improving Outcomes for Youth with ADHD: A Conceptual Framework for Combined Neurocognitive and Skill-Based Treatment Approaches
Chacko, A., Kofler, M., & Jarrett, M. (2014) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-014-0171-5 · Cited by 93 · see citing works
The muscarinic system, cognition and schizophrenia
Carruthers, S. P., Gurvich, C. T., & Rossell, S. L. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.05.011 · Cited by 90 · see citing works
Neuropsychological substrates and everyday functioning implications of prospective memory impairment in schizophrenia
Twamley, E. W., Woods, S. P., Zurhellen, C. H., Vertinski, M., Narvaez, J. M., Mausbach, B. T., Patterson, T. L., & Jeste, D. V. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2007.10.030 · Cited by 89 · see citing works
Compensatory cognitive training for people with severe mental illnesses in supported employment: A randomized controlled trial
Twamley, E. W., Thomas, K. R., Burton, C. Z., Vella, L., Jeste, D. V., Heaton, R. K., & McGurk, S. R. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2017.08.005 · Cited by 85 · see citing works
Self-citation
Impaired hippocampal-dependent memory and reduced parvalbumin-positive interneurons in a ketamine mouse model of schizophrenia
Koh, M. T., Shao, Y., Sherwood, A., & Smith, D. R. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.01.023 · Cited by 51 · see citing works
Executive functioning in men with schizophrenia and substance use disorders: influence of lifetime suicide attempts
Adan, A., Capella, M. D. M., Prat, G., Forero, D. A., López-Vera, S., & Navarro, J. F. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169943 · Cited by 50 · see citing works
Technology to assess and support self-management in serious mental illness
Depp, C. A., Moore, R. C., Perivoliotis, D., & Granholm, E. (2016) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2016.18.2/cdepp · Cited by 48 · see citing works
General functioning predicts reward and punishment learning in schizophrenia
Somlai, Z., Moustafa, A. A., Kéri, S., Myers, C. E., & Gluck, M. A. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2010.07.028 · Cited by 45 · see citing works
Can cognitive insight predict symptom remission in a first episode psychosis cohort?
O’Connor, J. A., Ellett, L., Ajnakina, O., Schoeler, T., Kollliakou, A., Trotta, A., Wiffen, B. D., Falcone, A. M., Di Forti, M., Murray, R. M., et al. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1210-9 · Cited by 37 · see citing works
Mapping hypofrontality during letter fluency task in schizophrenia: A multi-channel near-infrared spectroscopy study
Shimodera, S., Imai, Y., Kamimura, N., Morokuma, I., Fujita, H., Inoue, S., & Furukawa, T. A. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.01.039 · Cited by 24 · see citing works
An examination of neurocognition and symptoms as predictors of post-hospital community tenure in treatment resistant schizophrenia
Ahmed, A. O., Murphy, C. F., Latoussakis, V., McGovern, K. E., English, J., Bloch, A., Anthony, D. T., & Savitz, A. J. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.01.001 · Cited by 22 · see citing works
Social motivation and behavior in first-episode psychosis: Unique contributions to social quality of life and social functioning
Moe, A. M., Weiss, D. M., Pine, J. G., Wastler, H. M., & Breitborde, N. J. K. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.11.001 · Cited by 14 · see citing works
Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies
Stein, D. J., Szatmari, P., Gaebel, W., Berk, M., Vieta, E., Maj, M., de Vries, Y. A., Roest, A. M., de Jonge, P., Maercker, A., et al. (2020) · BMC Medicine · doi:10.1186/s12916-020-1495-2 · Cited by 264 · see citing works

Authors: Green, M. F., Kern, R. S., & Heaton, R. K.
Affiliations: University of California, Los Angeles (US)
University of California San Diego (US)
Corresponding author: Green, Michael F.
ORCID: Green, Michael F.
Kern, Robert S.
Heaton, Robert K.
Venue: Schizophrenia Research
Publisher: Elsevier BV
Published: 2004-12
Volume: 72
Issue: 1
Pages: 41-51
ISSN: 0920-9964 (ISSN-L)
DOI: 10.1016/j.schres.2004.09.009
OpenAlex: W2156436903
Cited by: 1,422
References: 53
Citations by year: 2026: 30 · 2025: 31 · 2024: 45 · 2023: 46 · 2022: 51 · 2021: 55 · 2020: 72 · 2019: 75 · 2018: 69 · 2017: 94 · 2016: 94 · 2015: 108 · 2014: 98 · 2013: 91 · 2012: 91
FWCI: 4.39
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Schizophrenia Research (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01mh022006-001)
U.S. Food and Drug Administration
National Institute of Mental Health (MH22006)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: schizophrenia, cognitive impairment
MeSH terms: Clinical Trials as Topic, Cognition Disorders, Humans, Longitudinal Studies, Rehabilitation, Vocational, Schizophrenia, Antipsychotic Agents, Treatment Outcome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks