Efficacy and feasibility of the Integrated Psychological Therapy for outpatients with schizophrenia in Greece: Final results of a RCT
Abstract
The goal of this study was to evaluate the efficacy and the feasibility of cognitive remediation group therapy in patients with schizophrenia in Greece. For this purpose, the cognitive part of the Integrated Psychological Therapy (IPT), focusing on neuro- and social cognition, was compared in a randomized controlled trial (RCT) with treatment as usual (TAU). 48 outpatients took part in the study. IPT groups received 20 biweekly 1-h-therapy sessions. A test-battery was assessed at baseline, after therapy, and at a 3-month follow-up. Regarding cognitive functioning, significant effects favouring IPT were found in working memory and social perception during therapy and at follow-up. No effects could be found in verbal memory and vigilance. Significant effects favoring IPT were found in negative symptoms, in insight and in general symptoms during therapy and at follow-up using the Positive and Negative Syndrome Scale (PANSS). No effects were evident in positive symptoms and in psychosocial functioning. Significant effects favoring TAU were found in the quality of life assessment at follow-up. The study supports evidence for the feasibility and efficacy of IPT in psychiatric care in Greece and it hopefully will initiate the broader use of evidenced-based treatments like IPT in Greek Psychiatry.
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Integrated psychological therapy is reported to improve insight relative to treatment as usual.
“Other psychological therapies that have also been reported to lead to improvement in insight relative to treatment as usual include integrated psychological therapy 170 , a self-management skills program 171 , and an adaptation to schizophrenia of an individualized treatment developed to help adults with diabetes accept their medical condition, called guided self-determination 172 .”
From Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments (2018) · cites this paper as [170]
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- Authors
- Rakitzi, S., Georgila, P., Efthimiou, K., & Mueller, D. R.
- Affiliations
- General Hospital of Athens G. Genimatas (GR)
- University Hospital of Bern (CH)
- Corresponding author
- Rakitzi, Stavroula
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2016-08
- Volume
- 242
- Pages
- 137-143
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2409285185
- Cited by
- 20
- References
- 48
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 1
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Bern Open Repository and Information System (University of Bern) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Keywords
- integrated psychological therapy, schizophrenia, cognitive remediation, group therapy, working memory, social perception, negative symptoms, insight, quality of life, outpatients, treatment efficacy, feasibility, Greece
- MeSH terms
- Adult, Cognition, Feasibility Studies, Female, Follow-Up Studies, Greece, Humans, Male, Middle Aged, Outpatients, Psychotherapy, Group, Quality of Life, Schizophrenia, Schizophrenic Psychology, Social Behavior, Social Perception, Cognitive Behavioral Therapy, Treatment Outcome
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