Intranasal oxytocin administration attenuates the ACTH stress response in monkeys

The oxytocin receptor system: structure, function, and regulation

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Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress

Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091

The role of corticotropin-releasing factor in depression and anxiety disorders

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Sniffing neuropeptides: A transnasal approach to the human brain

Born, J., Lange, T., Kern, W., McGregor, G. P., Bickel, U., & Fehm, H. L. (2002) · Nature Neuroscience · doi:10.1038/nn0602-849 · Cited by 1,356

OXYTOCIN MAY MEDIATE THE BENEFITS OF POSITIVE SOCIAL INTERACTION AND EMOTIONS1The purpose of this paper is to describe the neuroendocrine mechanisms of positive social interactions.1

Uvnäs-Moberg, K. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00056-0 · Cited by 966 · cited 2×

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Holsboer, F. (2001) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00352-9 · Cited by 575

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Cho, M. M., DeVries, A. C., Williams, J. R., & Carter, C. S. (1999) · Behavioral Neuroscience · doi:10.1037/0735-7044.113.5.1071 · Cited by 529

Neuroendocrine aspects of hypercortisolism in major depression

Parker, K. J., Schatzberg, A. F., & Lyons, D. M. (2003) · Hormones and Behavior · doi:10.1016/s0018-506x(02)00016-8 · Cited by 455

Oxytocin Attenuates Stress-Induced c-fos mRNA Expression in Specific Forebrain Regions Associated with Modulation of Hypothalamo–Pituitary–Adrenal Activity

Windle, R. J., Kershaw, Y. M., Shanks, N., Wood, S. A., Lightman, S. L., & Ingram, C. D. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3432-03.2004 · Cited by 408

Chapter 12 Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo-pituitary-adrenal axis

Neumann, I. D. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)39014-9 · Cited by 387

Intranasally applied l-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions

Chao, O. Y.-H., Mattern, C., Silva, A. M. D. S., Weßler, J., Ruocco, L. A., Nikolaus, S., Huston, J. P., & Pum, M. E. (2011) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2011.11.004 · Cited by 24

Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats

Nguyen, E. T., Caldwell, J. L., Streicher, J., Ghisays, V., Balmer, N. J., Estrada, C. M., & Solomon, M. B. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.08.045 · Cited by 25

Masturbation in the Animal Kingdom

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Oxytocin treatment in pediatric populations

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Validating the use of a commercial enzyme immunoassay to measure oxytocin in unextracted urine and saliva of the western lowland gorilla (Gorilla gorilla gorilla)

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L’ocytocine et la dépression du post-partum

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Oxytocin improves the ability of dogs to follow informative pointing: a neuroemotional hypothesis

Macchitella, L., Stegagno, T., Giaconella, R., di Sorrentino, E. P., Schino, G., & Addessi, E. (2016) · RENDICONTI LINCEI · doi:10.1007/s12210-016-0579-6 · Cited by 22

Intranasal oxytocin attenuates the human acoustic startle response independent of emotional modulation

Ellenbogen, M. A., Linnen, A., Cardoso, C., & Joober, R. (2014) · Psychophysiology · doi:10.1111/psyp.12263 · Cited by 24

Neurobiology of Social Behavior

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Kamikihito, a traditional Japanese Kampo medicine, increases the secretion of oxytocin in rats with acute stress

Tsukada, M., Ikemoto, H., Lee, X., Takaki, T., Tsuchiya, N., Mizuno, K., Inoue, T., Tsunokawa, Y., Okumo, T., Matsuyama, T., et al. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114218 · Cited by 22

Can positive welfare counterbalance negative and can net welfare be assessed?

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Effects of intranasal and peripheral oxytocin or gastrin-releasing peptide administration on social interaction and corticosterone levels in rats

Kent, P., Awadia, A., Zhao, L. L., Ensan, D., Silva, D., Cayer, C., James, J. S., Anisman, H., & Merali, Z. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.11.019 · Cited by 20

Oxytocin and vasopressin increase male-directed threats and vocalizations in female macaques

Jiang, Y., & Platt, M. L. (2018) · Scientific Reports · doi:10.1038/s41598-018-36332-0 · Cited by 20

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The effects of oxytocin on primates’ working memory depend on the emotional valence of contextual factors

Zarei, S. A., Sheibani, V., Tomaz, C. A. B., & Mansouri, F. A. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.12.050 · Cited by 17

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Damián, J. P., de Soto, L., Espindola, D., Gil, J., & van Lier, E. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.113282 · Cited by 18

Microbes, oxytocin and stress: Converging players regulating eating behavior

Cuesta‐Marti, C., Uhlig, F., Muguerza, B., Hyland, N. P., Clarke, G. A., & Schellekens, H. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13243 · Cited by 17

Effects of Chronic and Acute Intranasal Oxytocin Treatments on Temporary Social Separation in Adult Titi Monkeys (Plecturocebus cupreus)

Razo, R. A., Vázquez, M. D. L. V., Turcanu, P., Legrand, M., Lau, A. R., Weinstein, T. A. R., Goetze, L. R., & Bales, K. L. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.877631 · Cited by 13

Is Oxytocin Relevant for the Affective Disorders?

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Socio-behavioral dysfunction in disorders of hypothalamic-pituitary involvement: The potential role of disease-induced oxytocin and vasopressin signaling deficits

Clarke, L., Zyga, O., Pineo-Cavanaugh, P. L., Jeng, M., Fischbein, N. J., Partap, S., Katznelson, L. J., & Parker, K. J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104770 · Cited by 13

The role of oxytocin on peaceful associations and sociality in mammals

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Targeting the Oxytocin System to Ameliorate Early Life Depressive-Like Behaviors in Maternally-Separated Rats

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Genetic Variation in the Maternal Oxytocin System Affects Cortisol Responsiveness to Breastfeeding in Infants and Mothers

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A medication use evaluation of alendronate: compliance with administration guidelines.

Mersfelder, T. L., Armitstead, J. A., Ivey, M. F., & Cedars, M. I. (1999) · PubMed · Cited by 13

Oxytocin modulates mate-guarding behavior in marmoset monkeys

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Changes in face-specific neural processing explain reduced cuteness and approachability of infants with cleft lip

Huffmeijer, R., Eilander, J., Mileva‐Seitz, V. R., & Rippe, R. C. A. (2017) · Social Neuroscience · doi:10.1080/17470919.2017.1340336 · Cited by 12

Potential of Endogenous Oxytocin in Endocrine Treatment and Prevention of COVID-19

Wang, S. C., Zhang, F., Zhu, H. F., Yang, H.-P., Liu, Y., Wang, P., Parpura, V., & Wang, Y. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.799521 · Cited by 12

Evaluating changes in salivary oxytocin and cortisol following positive reinforcement training in two adult male western lowland gorillas (Gorilla gorilla gorilla)

Leeds, A., Good, J., Schook, M. W., Dennis, P. M., Stoinski, T. S., Willis, M. A., & Lukas, K. E. (2019) · Zoo Biology · doi:10.1002/zoo.21524 · Cited by 11

Effects of Oxytocin Administration on Oxidative Markers in the Temporal Lobe of Aged Rats

Balmuș, I.-M., Ciobica, A. S., Stoica, B. A., Lefter, R. M., Cojocaru, S., & Резніков, А. Г. (2019) · Neurophysiology · doi:10.1007/s11062-019-09785-w · Cited by 11

Closeness of all kinds: The role of oxytocin and vasopressin in the physiology of spiritual and religious behavior

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Intrahypothalamic effects of oxytocin on PVN CRH neurons in response to acute stress

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γ-amino butyric acid-enriched barley bran lowers adrenocorticotropic hormone and corticosterone levels in immobilized stressed rats

Abinaya, R., Pichiah, P. B. T., Thomas, S. S., Kim, S., Han, D.-W., Song, Y., Oh, S., & Cha, Y. (2016) · Journal of Food Biochemistry · doi:10.1111/jfbc.12324 · Cited by 10

Psycho-Behavioral Spiral of Disturbances in Prosocial Behavior, Stress Response, and Self-Regulation inSubstance-Related and Addictive Disorders

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Oxytocin modulates responses to inequity in dogs

Romero, T., Konno, A., Nagasawa, M., & Hasegawa, T. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.12.023 · Cited by 9

Intranasal oxytocin treatment does not attenuate the hypothalamo-pituitary-adrenal axis in beef heifers subjected to isolation stress or restraint and isolation stress

Wagner, B. K., Relling, A. E., Kieffer, J. D., & Parker, A. J. (2019) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2019.07.007 · Cited by 9

Oxytocin Experiments Shed Light on Mechanisms Shaping Prosocial and Antisocial Behaviors in Non-human Mammals

Smith, J. E., Petelle, M. B., Jerome, E. L., Cristofari, H., & Blumstein, D. T. (2017) · Integrative and Comparative Biology · doi:10.1093/icb/icx091 · Cited by 10

Social behaviour is altered in the insulin-regulated aminopeptidase knockout mouse

Burns, P. L., Bowditch, J., McFadyen, J. D., Loiacono, R. E., Albiston, A. L., Pham, V., & Chai, S. Y. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112150 · Cited by 9

The Olfactory System as a Route of Delivery for Agents to the Brain and Circulation

Genter, M. B., Krishan, M., & Prediger, R. D. (2015) · Wiley eBooks · doi:10.1002/9781118971758.ch19 · Cited by 9

Methods of Drug Delivery in Neurotrauma

Deng‐Bryant, Y., Readnower, R. D., Leung, L. Y., Tortella, F. C., & Shear, D. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3816-2_6 · Cited by 8

Effectiveness and safety of kamikihito, a traditional Japanese medicine, in managing anxiety among female patients with intractable chronic constipation

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Short communication: pharmacokinetics of oxytocin administered intranasally to beef cattle

Wagner, B. K., Relling, A. E., Kieffer, J. D., Moraes, L. E., & Parker, A. J. (2019) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2019.106387 · Cited by 7

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Pfeifer, A.-C., Ditzen, B., Neubauer, E., & Schiltenwolf, M. (2016) · Der Schmerz · doi:10.1007/s00482-016-0164-z · Cited by 7

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Mogilski, J. K., Wysocki, A., Reeve, S. D., Mitchell, V. E., Lunge, J., & Welling, L. L. M. (2019) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190649739.013.19 · Cited by 7

Cognitive bias in rats is not influenced by oxytocin

McGuire, M. C., Williams, K. L., Welling, L. L. M., & Vonk, J. M. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01306 · Cited by 6

Expression of oxytocin in hypothalamus and reduction of nociceptive stress following administration of Kamikihi-to in female rats

Maruyama, T., Shimizu, M., Ikeda, N., Baba, K., Yoshimura, M., & Ueta, Y. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.961135 · Cited by 6

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Prenatal Ethanol Exposure Increases Depressive-Like Behavior and Central Estrogen Receptor α and Oxytocin Expressions in Adult Female

Voles, M., He, F., Zhang, J., & Guo, X. (2012) · Cited by 6

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Anumandla, S. R., Bray, L. C. J., Thibeault, C. M., Hoang, R. V., Dascalu, S. M., Harris, F. C., & Goodman, P. H. (2011) · International Joint Conference on Neural Networks (IJCNN) · doi:10.1109/ijcnn.2011.6033647 · Cited by 5

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Tadjibaev, A. (2013) · International Journal of Prevention and Treatment of Substance Use Disorders · Cited by 4

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Oxytocin and Social Isolation: Nonapeptide Regulation of Social Homeostasis

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Wielpuetz, C., Kuepper, Y., Grant, P. S., Munk, A. J. L., & Hennig, J. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00486 · Cited by 3

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Weinhold, S. L., Göder, R., & Baier, P. C. (2015) · Springer eBooks · doi:10.1007/978-3-319-23078-8_18 · Cited by 3

Oxytocin administration rescues the negative impacts of social isolation on wound healing in mice

Steele, S. R., Ratuski, A. S., Hui, E. I., Mahoney, B. S., Geronimo, J. T., Huss, M. K., Parker, K. J., & Garner, J. P. (2025) · Hormones and Behavior · doi:10.1016/j.yhbeh.2025.105741 · Cited by 3

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Wagner, B. K., Relling, A. E., Kieffer, J. D., & Parker, A. J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0249323 · Cited by 3

Effect of oxytocin on lipid accumulation under inflammatory conditions in human macrophages

Karten, A., Vernice, N. A., Renna, H. A., Carsons, S. E., DeLeon, J. R., Pinkhasov, A., Gomolin, I. H., Glass, D. S., Reiss, A. B., & Kasselman, L. J. (2021) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2021.104604 · Cited by 4

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Broom, D. M., & Johnson, K. G. (2019) · Animal welfare · doi:10.1007/978-3-030-32153-6_5 · Cited by 2

Oxytocin reduces interoceptive influences on empathy-for-pain in the anterior insulaPreprint

Betka, S., van Praag, C. G., Rae, C. L., Pfeifer, G., Sequeira, H., Duka, T., & Critchley, H. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.22.465431 · Cited by 2

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Ochi, G., Ohara, N., & Kameo, H. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.15.649015 · Cited by 2

Oral Supplementation of L-Carnosine Attenuates Acute-Stress-Induced Corticosterone Release and Mitigates Anxiety in CD157 Knockout Mice

Tsuji, T., Furuhara, K., Guo, E., Wu, Y., Zhong, J., Higashida, H., Yamamoto, Y., & Tsuji, C. (2024) · Nutrients · doi:10.3390/nu16172821 · Cited by 1

Oxytocin receptor neurons in the paraventricular thalamus as a nexus for social behaviour and fear

Yamamuro, K., Ikehara, M., Noriyama, Y., Okuda, M., Okumura, K., Matsuoka, K., Kashida, N., Ishida, R., Takeda, T., Toritsuka, M., et al. (2025) · Brain · doi:10.1093/brain/awaf421 · Cited by 2

New Therapeutic Strategies for the Treatment of Brain Tumor

Hashizume, R. (2011) · InTech eBooks · doi:10.5772/23997 · Cited by 1

Urinary oxytocin and cortisol concentrations vary by group type in male western lowland gorillas (Gorilla gorilla gorilla) in North American zoos

Leeds, A., Schook, M. W., Dennis, P. M., Stoinski, T. S., Willis, M. A., & Lukas, K. E. (2022) · Primates · doi:10.1007/s10329-022-01037-6 · Cited by 1

Tales from the life and lab of a female social neuroscientist

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Oxytocin alters leukogram composition in Bos indicus cattle exposed to short-duration transportation

Wagner, B. K., Martin, D. G., Rudd, D., & Parker, A. J. (2021) · Animal Production Science · doi:10.1071/an20393 · Cited by 1

Psychobiologie: Die Interaktion zwischen Psyche und Soma

Ditzen, B., & Gaab, J. (2009) · Springer eBooks · doi:10.1007/978-3-642-01060-6_12 · Cited by 1

Efeito da ocitocina sobre a ansiedade experimental induzida em voluntários saudáveis

Chaves, D. I. (2007) · doi:10.11606/d.60.2007.tde-21052007-100039 · Cited by 1

Oxytocin, Aggression, and Neural Activity in the Naked Mole-rat

Hathaway, G. A. (2014) · TSpace (University of Toronto) · Cited by 1

Visibility concepts and measurement techniques for aviation purposes

Schappert, G. T. (1971) · ROSA P · Cited by 1

Understanding the causes of anxiety

Simpson, H. B., Neria, Y., Lewis‐Fernández, R., & Schneier, F. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511777578.015

The Role of Attachment in Emotion Regulation of Traumatic Stress

Arıkan, G. (2011) · ePrints Soton (University of Southampton)

Alcohol Consumption: A Study of Genetic and Environmental Correlates with Focus on the Stress System

Todkar, A. (2016) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Fra offer til overgriper - Når relasjonsskadde unge begår seksuelle overgrep

Ramberg, K. S. B. (2014) · NORA - Norwegian Open Research Archives

Physiological correlates of emotion regulation in depersonalization disorder

Monde, K.-M. (2014) · CUNY Academic Works (City University of New York)

Oxytocin, Vasopressin, and Development of Social Behavior in Primates

Bales, K. L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804042-3.00094-4

Computational analysis of the response of the monoaminergic neurotransmitter system and stress- and sex-steroid hormone systems to administration of antidepressant drugs

Camacho, M. B. (2018) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)

L’ocytocine et la dépression du post-partum

Cardaillac, C., Rua, C., Simon, E. G., & El‐Hage, W. (2017) · Sages-Femmes · doi:10.1016/j.sagf.2017.04.005

Pharmacological Characterisation of Novel Oxytocin and Vasopressin Receptor Ligands

Gulliver, D. W. (2021) · The Sydney eScholarship Repository (The University of Sydney)

Oxytocin and Social Sensitivity: Implications for Vulnerability to Stress and Depressive Symptoms

McQuaid, R. J. (2015) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2015-11083

Effectiveness of Japanese herbal medicines (Kampo) for stress

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Association of oxytocin gene polymorphism with psychological distress, suicidal ideation and relapse in alcohol-dependent patients

Mach, A., Klimkiewicz, A., Fudalej, S., Jakubczyk, A., Kopera, M., Burmeister, M., Brower, K. J., & Wojnar, M. (2021) · Alcoholism and Drug Addiction · doi:10.5114/ain.2021.109540

The Neuroendocrine and Cardiovascular Responses to a Pup in Male Prairie Voles (M. ochrogaster)

Kenkel, W. M. (2013) · Figshare

Oxytocin, Social Interactions and Coping: Implications for Depression

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Wynberg, H. (2010) · Utrecht University Repository (Utrecht University)

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Awadia, A. (2015) · uO Research (University of Ottawa)

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