The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Oxysterols in the pathogenesis of major chronic diseases
Open accessAbstract
Pathological accumulation of 27-carbon intermediates or end-products of cholesterol metabolism, named oxysterols, may contribute to the onset and especially to the development of major chronic diseases in which inflammation, but also oxidative damage and to a certain extent cell death, are hallmarks and primary mechanisms of progression. Indeed, certain oxysterols exercise strong pro-oxidant and pro-inflammatory effects at concentrations detectable in the lesions typical of atherosclerosis, neurodegenerative diseases, inflammatory bowel diseases, age-related macular degeneration, and other pathological conditions characterized by altered cholesterol uptake and/or metabolism.
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Cites
Pathways towards and Away from Alzheimer’s Disease
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An oxysterol signalling pathway mediated by the nuclear receptor LXRα
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Oxysterols and atherosclerosis
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Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
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Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH
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Cited by
Molecular mechanisms of ROS production and oxidative stress in diabetes
Newsholme, P., Cruzat, V. F., Keane, K. N., Carlessi, R., & de Bittencourt, P. I. H. (2016) · Biochemical Journal · doi:10.1042/bcj20160503c · Cited by 878
Jang, J., Park, S., Jin Hur, H., Cho, H.-J., Hwang, I., Pyo Kang, Y., Im, I., Lee, H., Lee, E., Yang, W., et al. (2016) · Nature Communications · doi:10.1038/ncomms13129 · Cited by 166
Indaram, M., Ma, W., Zhao, L., Fariss, R. N., Rodriguez, I. R., & Wong, W. T. (2015) · Scientific Reports · doi:10.1038/srep09144 · Cited by 101
Yammine, A., Zarrouk, A., Nury, T., Vejux, A., Latruffe, N., Vervandier-Fasseur, D., Samadi, M., Mackrill, J. J., Greige-Gerges, H., Auezova, L., et al. (2020) · Cells · doi:10.3390/cells9112346 · Cited by 79
Cholesterol metabolism: from lipidomics to immunology
Griffiths, W. J., & Wang, Y. (2022) · Journal of Lipid Research · doi:10.1016/j.jlr.2021.100165 · Cited by 68
Metadata
- Authors
- Poli, G., Biasi, F., & Leonarduzzi, G.
- Venue
- Redox Biology
- Publisher
- Elsevier BV
- Published
- 2013
- Volume
- 1
- Issue
- 1
- Pages
- 125-130
- ISSN
- 2213-2317 (ISSN-L)
- OpenAlex
- W2018956263
- Cited by
- 301
- References
- 44
- FWCI
- 22.45
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
