The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms
Open accessAbstract
This article provides a succinct but limited overview of the protective and deleterious effects of reactive oxygen and nitrogen species in a clinical context. Reactive oxygen species include superoxide, hydrogen peroxide, single oxygen and lipid peroxides. Reactive nitrogen species include species derived from nitric oxide. This review gives a brief overview of the reaction chemistry of these species, the role of various enzymes involved in the generation and detoxification of these species in disease mechanisms and drug toxicity and the protective role of dietary antioxidants. I hope that the graphical review will be helpful for teaching both the first year medical and graduate students in the U.S. and abroad the fundamentals of reactive oxygen and nitrogen species in redox biology and clinical medicine.
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Cites
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Cited by
Griendling, K. K., Touyz, R. M., Zweier, J. L., Dikalov, S., Chilian, W., Chen, Y.-R., Harrison, D. G., & Bhatnagar, A. (2016) · Circulation Research · doi:10.1161/res.0000000000000110 · Cited by 444
Formation of UV-induced DNA damage contributing to skin cancer development
Cadet, J., & Douki, T. (2018) · Photochemical & Photobiological Sciences · doi:10.1039/c7pp00395a · Cited by 435
Antioxidant therapy for treatment of inflammatory bowel disease: Does it work?
Moura, F. A., de Andrade, K. Q., dos Santos, J. C. F., Araújo, O. R. P., & Goulart, M. O. F. (2015) · Redox Biology · doi:10.1016/j.redox.2015.10.006 · Cited by 381
Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
Giordano, S., Darley-Usmar, V., & Zhang, J. (2014) · Redox Biology · doi:10.1016/j.redox.2013.12.013 · Cited by 366
Do you know the sex of your cells?
Shah, K., McCormack, C. E., & Bradbury, N. A. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00281.2013 · Cited by 219
Metadata
- Authors
- Kalyanaraman, B.
- Venue
- Redox Biology
- Publisher
- Elsevier BV
- Published
- 2013
- Volume
- 1
- Issue
- 1
- Pages
- 244-257
- ISSN
- 2213-2317 (ISSN-L)
- OpenAlex
- W2051906209
- Cited by
- 502
- References
- 30
- FWCI
- 20.17
- Type
- journal article
- Language
- en
- Open access
- gold
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
