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Cited by 103Schizophrenia research and treatmentCognitive Functions and MemoryDementia and Cognitive Impairment Research

The DOI matches its Crossref record; 33 of the 34 references it cites were found in a registry or an index.

Does age matter? Effects of cognitive rehabilitation across the age span

Wykes, Til, Reeder, Clare, Landau, Sabine, Matthiasson, Pall, Haworth, Elke, Hutchinson, Chloe·2009·Schizophrenia Research
DOI 10.1016/j.schres.2009.05.025
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Abstract

Background Cognitive remediation (CR) therapy in its various disguises can be helpful for people with schizophrenia but it is not clear if patient characteristics are likely to interfere with its effectiveness.Methodology This paper describes the assessment of one putative moderating variable, age, on the outcome of CRT in a rigorous randomised control trial with memory, cognitive flexibility and planning as primary outcomes and social behaviour, symptoms and self-esteem as secondary outcomes. Calendar age was divided into younger (< 40; N55) and older (40 or more years; N30). There were no differences between the groups at baseline in their cognitive, social or demographic data except on predicted variables.Results Younger people benefited more from cognitive remediation in two of the three cognitive domains tested. In the memory domain both groups benefited. Only negative symptoms showed a moderating effect of age on CRT, where again the younger group showed improvements in the context of CRT but the older group did not. When older people did show a cognitive advantage in memory following therapy this cognitive improvement benefited social behaviour.Conclusion CRT needs some modification to increase the benefits to older participants. However, any cognitive improvements do still seem to have a beneficial effect.

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  1. Wechsler, D., 1999. Wechsler Adult Intelligence Scale (WAIS-III), Pearson.

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Metadata

Authors
Wykes, T., Reeder, C., Landau, S., Matthiasson, P., Haworth, E., & Hutchinson, C.
Affiliations
  • King's College London (GB)
  • South London and Maudsley NHS Foundation Trust (GB)
Corresponding author
Wykes, Til
ORCID
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2009-09
Volume
113
Issue
2-3
Pages
252-258
ISSN
0920-9964 (ISSN-L)
DOI
10.1016/j.schres.2009.05.025
OpenAlex
W2123345515
Cited by
103
References
34
Citations by year
2025: 5 · 2024: 3 · 2023: 5 · 2022: 2 · 2021: 8 · 2020: 8 · 2019: 10 · 2018: 3 · 2017: 3 · 2016: 10 · 2015: 7 · 2014: 5 · 2013: 13 · 2012: 12
FWCI
4.33
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Schizophrenia Research (publishedVersion)
  • PubMed (publishedVersion)
  • Research Portal (King's College London) (submittedVersion)
  • Hirsla (Landspítali University Hospital) (submittedVersion)
Funders
  • National Institute for Health and Care Research
  • Economic and Social Research Council (PTA-026-27-0520)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
cognitive remediation, cognitive rehabilitation
MeSH terms
Adolescent, Adult, Age Factors, Aged, Aging, Analysis of Variance, Cognition Disorders, Female, Hierarchy, Social, Humans, Male, Memory, Middle Aged, Neuropsychological Tests, Problem Solving, Psychomotor Performance, Schizophrenia, Self Concept, Cognitive Behavioral Therapy, Single-Blind Method, Treatment Outcome, Young Adult

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