Impact of Polypropylene Microplastics and Chemical Pollutants on European Sea Bass (Dicentrarchus labrax) Gut Microbiota and Health
Open accessAbstract
Plastic pollution has become a global problem for marine ecosystems. Microplastics (MPs) are consumed by several marine organisms, including benthic and pelagic fish species that confuse them with food sources, thus contributing to bioaccumulation along the food chain. In addition to structural intestinal damage, ingestion of MPs represents a pathway for fish exposure to potentially hazardous chemicals, too. Most of them are endocrine disrupters, genotoxic or induce immune depression in fish. Accordingly, we assessed the combined toxicological effects of microplastics (MPs) and adsorbed pollutants by adding them to marine fish diet. European sea bass (Dicentrarchus labrax) juveniles were fed for 60 days with feeds containing polypropylene MPs, either virgin or contaminated with chemical pollutants (a blend of dichlorodiphenyldichloroethylene, chlorpyrifos, and benzophenone-3). The data demonstrated a synergic action of MPs and chemical pollutants to induce an inflammatory-like response in distal intestine of sea bass as shown by the up regulation of cytokine il-6 and tnf-α expression. Morphological analysis detected the presence of a focus of lymphocytes in anterior and posterior intestinal segments of fish fed with contaminants in the diet. With regard to microbiota, significant changes in bacterial species richness, beta diversity, and composition of gut microbiota were observed as a consequence of both pollutants and polluted MPs ingestion. These perturbations in gut microbial communities, including the reduction of beneficial lactic acid bacteria and the increase in potential pathogenic microorganism (Proteobacteria and Vibrionales), were undeniable signs of intestinal dysbiosis, which in turn confirmed the signs of inflammation caused by pollutants, especially when combined with MPs. The results obtained in this study provide, therefore, new insights into the potential risks of ingesting MPs as pollutant carriers in marine fish.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
MPs may adsorb environmental contaminants because of their lipophilicity and act as carriers for hazardous chemicals such as organic contaminants and heavy metals.
“Moreover, MPs may adsorb contaminants present in the environment because of their lipophilicity [24]; in fact, once arriving in the seawater, they change their nature in response to physicochemical and biological ageing processes [25] and, in this way, act as carriers for very hazardous chemicals (e.g., organic contaminants and heavy metals) [26,27].”
From Is Wild Marine Biota Affected by Microplastics? (2022) · cites this paper as [27]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., et al. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0209-9 · Cited by 23,742 · see citing works
Plastic waste inputs from land into the ocean
Jambeck, J. R., Geyer, R., Wilcox, C., Siegler, T. R., Perryman, M., Andrady, A., Narayan, R., & Law, K. L. (2015) · Science · doi:10.1126/science.1260352 · Cited by 13,163 · see citing works
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
Langille, M. G. I., Zaneveld, J., Caporaso, J. G., McDonald, D., Knights, D., Reyes, J. A., Clemente, J. C., Burkepile, D. E., Vega Thurber, R. L., Knight, R., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2676 · Cited by 9,116 · see citing works
UniFrac: a New Phylogenetic Method for Comparing Microbial Communities
Lozupone, C., & Knight, R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8228-8235.2005 · Cited by 8,227 · see citing works
Host-gut microbiota metabolic interactions
Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760 · see citing works
STAMP: statistical analysis of taxonomic and functional profiles
Parks, D. H., Tyson, G. W., Hugenholtz, P., & Beiko, R. G. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu494 · Cited by 4,200 · see citing works
Proteobacteria: Microbial signature of dysbiosis in gut microbiota
Shin, N.-R., Whon, T. W., & Bae, J.-W. (2015) · Trends in Biotechnology · doi:10.1016/j.tibtech.2015.06.011 · Cited by 3,954 · see citing works
Plastic and Human Health: A Micro Issue?
Wright, S. L., & Kelly, F. J. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b00423 · Cited by 3,413 · see citing works
Life in the “plastisphere”: microbial communities on plastic marine debris
Zettler, E. R., Mincer, T. J., & Amaral-Zettler, L. A. (2013) · Environmental Science & Technology · doi:10.1021/es401288x · Cited by 3,368 · see citing works
Transport and release of chemicals from plastics to the environment and to wildlife
Teuten, E. L., Saquing, J. M., Knappe, D. R. U., Barlaz, M. A., Jonsson, S., Björn, A., Rowland, S. J., Thompson, R. C., Galloway, T. S., Yamashita, R., et al. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0284 · Cited by 2,938 · see citing works
Colonic Health: Fermentation and Short Chain Fatty Acids
Wong, J. M. W., de Souza, R., Kendall, C. W. C., Emam, A., & Jenkins, D. J. A. (2006) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200603000-00015 · Cited by 2,739 · see citing works
Lozupone, C., Hamady, M., Kelley, S. T., & Knight, R. D. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.01996-06 · Cited by 2,717 · see citing works
Gasque, G., Conway, S., Huang, J., Rao, Y., & Vosshall, L. B. (2013) · Scientific Reports · doi:10.1038/srep02120 · Cited by 2,320 · see citing works
Wastewater Treatment Works (WwTW) as a Source of Microplastics in the Aquatic Environment
Murphy, F., Ewins, C., Carbonnier, F., & Quinn, B. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.5b05416 · Cited by 2,098 · see citing works
Ingested plastic transfers hazardous chemicals to fish and induces hepatic stress
Rochman, C. M., Hoh, E., Kurobe, T., & Teh, S. J. (2013) · Scientific Reports · doi:10.1038/srep03263 · Cited by 2,063 · see citing works
Gut microbiota and IBD: causation or correlation?
Ni, J., Wu, G. D., Albenberg, L., & Tomov, V. T. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.88 · Cited by 1,778 · see citing works
Carbery, M., O'Connor, W., & Palanisami, T. (2018) · Environment International · doi:10.1016/j.envint.2018.03.007 · Cited by 1,425 · see citing works
Potential beneficial effects of butyrate in intestinal and extraintestinal diseases
Canani, R. B. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i12.1519 · Cited by 1,381 · see citing works
Probiotic Mechanisms of Action
Bermúdez-Brito, M., Plaza‐Díaz, J., Muñoz‐Quezada, S., Gómez‐Llorente, C., & Gil, Á. (2012) · Annals of Nutrition and Metabolism · doi:10.1159/000342079 · Cited by 1,276 · see citing works
Adsorption of trace metals to plastic resin pellets in the marine environment
Holmes, L., Turner, A., & Thompson, R. C. (2011) · Environmental Pollution · doi:10.1016/j.envpol.2011.08.052 · Cited by 1,074 · see citing works
Role of gastrointestinal microbiota in fish
Nayak, S. K. (2010) · Aquaculture Research · doi:10.1111/j.1365-2109.2010.02546.x · Cited by 1,073 · see citing works
Qiao, R., Sheng, C., Lu, Y., Zhang, Y., Ren, H., & Lemos, B. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.01.245 · Cited by 971 · see citing works
Distribution of plastic polymer types in the marine environment; A meta-analysis
Erni-Cassola, G., Zadjelovic, V., Gibson, M. I., & Christie-Oleza, J. A. (2019) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.02.067 · Cited by 874 · see citing works
Polystyrene microplastics induce microbiota dysbiosis and inflammation in the gut of adult zebrafish
Jin, Y., Xia, J., Pan, Z., Yang, J., Wang, W., & Fu, Z. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2017.12.088 · Cited by 873 · see citing works
Organic micropollutants in marine plastics debris from the open ocean and remote and urban beaches
Hirai, H., Takada, H., Ogata, Y., Yamashita, R., Mizukawa, K., Saha, M., Kwan, C. S., Moore, C. J., Gray, H. E., Laursen, D., et al. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.06.004 · Cited by 862 · see citing works
Avio, C. G., Gorbi, S., & Regoli, F. (2015) · Marine Environmental Research · doi:10.1016/j.marenvres.2015.06.014 · Cited by 798 · see citing works
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
Hirt, N., & Body–Malapel, M. (2020) · Particle and Fibre Toxicology · doi:10.1186/s12989-020-00387-7 · Cited by 785 · see citing works
Rochman, C. M., Kurobe, T., Flores, I., & Teh, S. J. (2014) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2014.06.051 · Cited by 762 · see citing works
Lactic acid bacteria in fish: a review
Ringø, E., & Gatesoupe, F.-J. (1998) · Aquaculture · doi:10.1016/s0044-8486(97)00299-8 · Cited by 754 · see citing works
A review on the interactions between gut microbiota and innate immunity of fish: Table 1
D, G. R. G., & Balcázar, J. L. (2008) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2007.00343.x · Cited by 719 · see citing works
Ogata, Y., Takada, H., Mizukawa, K., Hirai, H., Iwasa, S., Endo, S., Mato, Y., Saha, M., Okuda, K., Nakashima, A., et al. (2009) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2009.06.014 · Cited by 704 · see citing works
Microplastics pollution in different aquatic environments and biota: A review of recent studies
Rezania, S., Park, J., Din, M. F. M., Taib, S. M., Talaiekhozani, A., Yadav, K. K., & Kamyab, H. (2018) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2018.05.022 · Cited by 679 · see citing works
Ory, N. C., Sobral, P., Ferreira, J. L., & Thiel, M. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.01.175 · Cited by 676 · see citing works
A new view of the fish gut microbiome: advances from next-generation sequencing
Ghanbari, M., Kneifel, W., & Domig, K. J. (2015) · Aquaculture · doi:10.1016/j.aquaculture.2015.06.033 · Cited by 669 · see citing works
Ingestion of microplastics by fish and its potential consequences from a physical perspective
Jovanović, B. (2017) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.1913 · Cited by 637 · see citing works
Pedà, C., Caccamo, L., Fossi, M. C., Gai, F., Andaloro, F., Genovese, L., Perdichizzi, A., Romeo, T., & Maricchiolo, G. (2016) · Environmental Pollution · doi:10.1016/j.envpol.2016.01.083 · Cited by 611 · see citing works
Wang, W., Gao, H. J., Jin, S., Li, R., & Na, G. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.01.113 · Cited by 609 · see citing works
Lazăr, V., Diţu, L.-M., Pîrcălăbioru, G. G., Gheorghe, I., Curuțiu, C., Holban, A. M., Picu, A. A., Petcu, L. M., & Chifiriuc, M. C. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01830 · Cited by 536 · see citing works
Wan, Z., Wang, C., Zhou, J., Shen, M., Wang, X., Fu, Z., & Jin, Y. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.11.070 · Cited by 503 · see citing works
Gouin, T., Roche, N. L., Lohmann, R., & Hodges, G. (2011) · Environmental Science & Technology · doi:10.1021/es1032025 · Cited by 468 · see citing works
Bioavailability and toxicity of microplastics to fish species: A review.
Wang, W.-F., Ge, J., & Yu, X. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.109913 · Cited by 465 · see citing works
Microplastics in Livers of European Anchovies (Engraulis encrasicolus, L.)
Collard, F., Gilbert, B., Compère, P., Eppe, G., Das, K., Jauniaux, T., & Parmentier, E. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.07.089 · Cited by 438 · see citing works
Zhao, W., Dao, C. A., Karim, M., Marta Gómez-chiarri, G., Rowley, D. C., & Nelson, D. R. (2016) · BMC Microbiology · doi:10.1186/s12866-015-0617-z · Cited by 424 · see citing works
Lu, L., Luo, T., Zhao, Y., Cai, C., Fu, Z., & Jin, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.02.380 · Cited by 423 · see citing works
Gonçalves, P., Araújo, J. R., & Santo, J. P. D. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izx029 · Cited by 396 · see citing works
Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis
Fackelmann, G., & Sommer, S. (2019) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2019.04.030 · Cited by 385 · see citing works
Wang, Y., Hamid, N., Deng, S., Jia, P., & Pei, D. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122795 · Cited by 322 · see citing works
Barboza, L. G. A., Vieira, L. R., & Guilhermino, L. M. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2017.12.082 · Cited by 318 · see citing works
Critchell, K., & Hoogenboom, M. O. (2018) · PLOS ONE · doi:10.1371/journal.pone.0193308 · Cited by 310 · see citing works
Why We Need an International Agreement on Marine Plastic Pollution
Borrelle, S. B., Rochman, C. M., Liboiron, M., Bond, A. L., Lusher, A., Bradshaw, H., & Provencher, J. F. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1714450114 · Cited by 286 · see citing works
Huang, J.-N., Wen, B., Zhu, J.-G., Zhang, Y.-S., Gao, J., & Chen, Z. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138929 · Cited by 277 · see citing works
Pirsaheb, M., Hossini, H., & Makhdoumi, P. (2020) · Process Safety and Environmental Protection · doi:10.1016/j.psep.2020.05.050 · Cited by 276 · see citing works
Espinosa‐Ruíz, C., Esteban, M. Á., & Cuesta, A. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.10.072 · Cited by 267 · see citing works
Refstie, S., Sahlstrøm, S., Bråthen, E., et al. (2005) · Aquaculture · doi:10.1016/j.aquaculture.2005.01.001 · Cited by 263 · see citing works
Virgin microplastics are not causing imminent harm to fish after dietary exposure
Jovanović, B., Gökdağ, K., Güven, O., Emre, Y., Whitley, E. M., & Kideys, A. E. (2018) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2018.03.016 · Cited by 263 · see citing works
Gut microbiota of aquatic organisms: A key endpoint for ecotoxicological studies
Evariste, L., Barret, M., Mottier, A., Mouchet, F., Gauthier, L., & Pinelli, É. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.02.101 · Cited by 262 · see citing works
Why small plastic particles may pose a big problem in the oceans
Betts, K. S. (2008) · Environmental Science & Technology · doi:10.1021/es802970v · Cited by 242 · see citing works
Persistent organic pollutants in plastic marine debris found on beaches in San Diego, California
Van, A., Rochman, C. M., Flores, E. M., Hill, K. L., Vargas, E., Vargas, S. A., & Hoh, E. (2011) · Chemosphere · doi:10.1016/j.chemosphere.2011.09.039 · Cited by 242 · see citing works
Organic pollutants in marine plastic debris from Canary Islands beaches
Camacho, M., Herrera, A., Gómez, M., Acosta-Dacal, A. C., Martínez, I., Henríquez‐Hernández, L. A., & Luzardo, O. P. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.12.422 · Cited by 242 · see citing works
Self-citationLiang, Y., Zhan, J., Liu, D., Luo, M., Han, J., Liu, X., Liu, C., Cheng, Z. Z., Zhou, Z., & Wang, P. (2019) · Microbiome · doi:10.1186/s40168-019-0635-4 · Cited by 241 · see citing works
Microplastic ingestion cause intestinal lesions in the intertidal fish Girella laevifrons
Ahrendt, C., Pérez‐Venegas, D., Urbina, M. A., González, C., Echeveste, P., Aldana, M., Pulgar, J., & Galbán-Malagón, C. J. (2019) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2019.110795 · Cited by 232 · see citing works
Terova, G., Rimoldi, S., Ascione, C., Gini, E., Ceccotti, C., & Gasco, L. (2019) · Reviews in Fish Biology and Fisheries · doi:10.1007/s11160-019-09558-y · Cited by 227 · see citing works
Self-citationEspinosa‐Ruíz, C., Cuesta, A., & Esteban, M. Á. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.07.006 · Cited by 219 · see citing works
Mechanisms and the role of probiotic Bacillus in mitigating fish pathogens in aquaculture
Kuebutornye, F. K. A., Abarike, E. D., Lu, Y., Hlordzi, V., Sakyi, M. E., Afriyie, G., Wang, Z., Li, Y., & Xie, C. X. (2020) · Fish Physiology and Biochemistry · doi:10.1007/s10695-019-00754-y · Cited by 213 · see citing works
Nanoplastics impair the intestinal health of the juvenile large yellow croaker Larimichthys crocea
Gu, H., Wang, S., Wang, X., Yu, X., Hu, M., Huang, W., & Wang, Y. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122773 · Cited by 205 · see citing works
Transfer of PCBs from Microplastics under Simulated Gut Fluid Conditions Is Biphasic and Reversible
Mohamed Nor, N. H., & Koelmans, A. A. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.8b05143 · Cited by 186 · see citing works
Rimoldi, S., Gini, E., Iannini, F., Gasco, L., & Terova, G. (2019) · Animals · doi:10.3390/ani9040143 · Cited by 183 · see citing works
Self-citationMicroplastic ingestion by Atlantic chub mackerel (Scomber colias) in the Canary Islands coast
Herrera, A., Štindlová, A., Martínez, I., Rapp, J., Romero-Kutzner, V., Samper, M. D., Martínez, T. M., Aguiar‐González, B., Packard, T. T., & Gómez, M. (2019) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2018.12.022 · Cited by 157 · see citing works
Self-citationde Sales‐Ribeiro, C., Brito‐Casillas, Y., Fernández, A., & Caballero, M. J. (2020) · Scientific Reports · doi:10.1038/s41598-020-69062-3 · Cited by 152 · see citing works
Karbalaei, S., Hanachi, P., Rafiee, G., Seifori, P., & Walker, T. R. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.123980 · Cited by 140 · see citing works
Carda‐Diéguez, M., Mira, Á., & Fouz, B. (2013) · FEMS Microbiology Ecology · doi:10.1111/1574-6941.12236 · Cited by 139 · see citing works
Polyethylene microplastics increase the toxicity of chlorpyrifos to the marine copepod Acartia tonsa
Bellas, J., & Gil-Luna, I. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114059 · Cited by 130 · see citing works
Gut Microbiome Toxicity: Connecting the Environment and Gut Microbiome-Associated Diseases
Tu, P., Chi, L., Bodnar, W. M., Zhang, Z., Gao, B., Bian, X., Stewart, J. R., Fry, R. C., & Lü, K. (2020) · Toxics · doi:10.3390/toxics8010019 · Cited by 130 · see citing works
Rimoldi, S., Finzi, G., Ceccotti, C., Girardello, R., Grimaldi, A., Ascione, C., & Terova, G. (2016) · Fisheries and aquatic sciences · doi:10.1186/s41240-016-0041-9 · Cited by 127 · see citing works
Self-citationRimoldi, S., Antonini, M., Gasco, L., Moroni, F., & Terova, G. (2021) · Fish Physiology and Biochemistry · doi:10.1007/s10695-020-00918-1 · Cited by 122 · see citing works
Self-citationZhang, J., Meng, H., Kong, X., Cheng, X., Ma, T., He, H., Du, W., Yang, S., Li, S., & Zhang, L. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.116767 · Cited by 122 · see citing works
Liu, C., Sun, D., Zhu, J., & Liu, W. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03279 · Cited by 121 · see citing works
Zeytin, S., Wagner, G., Mackay-Roberts, N., Gerdts, G., Schuirmann, E., Klockmann, S., & Slater, M. J. (2020) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2020.111210 · Cited by 115 · see citing works
Terova, G., Díaz, N., Rimoldi, S., Ceccotti, C., Gliozheni, E., & Piferrer, F. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160332 · Cited by 114 · see citing works
Self-citationAdika, S. A., Mahu, E., Crane, R. A., Marchant, R., Montford, J., Folorunsho, R., & Gordon, C. (2020) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2020.110998 · Cited by 110 · see citing works
Immunomodulatory effects of environmental endocrine disrupting chemicals
Kuo, C., Yang, S., Kuo, P., & Hung, C. (2012) · The Kaohsiung Journal of Medical Sciences · doi:10.1016/j.kjms.2012.05.008 · Cited by 106 · see citing works
Li, J., Fang, B., Pang, G., Zhang, M., & Ren, F. (2019) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2019.05.018 · Cited by 104 · see citing works
Güven, O., Bach, L., Munk, P., Dinh, K. V., Mariani, P., & Nielsen, T. G. (2018) · Aquatic Toxicology · doi:10.1016/j.aquatox.2018.03.011 · Cited by 103 · see citing works
Ašmonaitė, G., Sundh, H., Asker, N., & Almroth, B. C. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.8b04848 · Cited by 103 · see citing works
Moser, G., & McLachlan, M. S. (2001) · Chemosphere · doi:10.1016/s0045-6535(00)00551-8 · Cited by 102 · see citing works
Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR
Manzella, C. R., Singhal, M., Alrefai, W. A., Saksena, S., Dudeja, P. K., & Gill, R. K. (2018) · Scientific Reports · doi:10.1038/s41598-018-24213-5 · Cited by 102 · see citing works
Rimoldi, S., Torrecillas, S., Montero, D., Gini, E., Makol, A., Valdenegro, V., Izquierdo, M. S., & Terova, G. (2020) · PLoS ONE · doi:10.1371/journal.pone.0231494 · Cited by 98 · see citing works
Self-citationKroon, F. J., Motti, C. A., Jensen, L. H., & Berry, K. (2018) · Scientific Reports · doi:10.1038/s41598-018-34590-6 · Cited by 97 · see citing works
Microplastics in Marine Food Webs
Setälä, O., Lehtiniemi, M., Coppock, R., & Cole, M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813747-5.00011-4 · Cited by 96 · see citing works
Dantas, N. C. F. M., Duarte, O. S., Ferreira, W. C., Ayala, A. P., Rezende, C. F., & Feitosa, C. V. (2020) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2020.110959 · Cited by 89 · see citing works
Wang, X., Wang, X., Xing, H., et al. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.04.015 · Cited by 77 · see citing works
Cardozo, A. L. P., Gentil, E., Filho, J. L. R., Moteiro, I. B., Scandolo, T. M., & Dantas, D. V. (2018) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2018.03.010 · Cited by 75 · see citing works
Dolar, A., Selonen, S., van Gestel, C. A. M., et al. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.144900 · Cited by 74 · see citing works
Ingestion of microplastics by pelagic fish from the Moroccan Central Atlantic coast
Maaghloud, H., Houssa, R., Ouansafi, S., Bellali, F., Bouqdaoui, K. E., Charouki, N., & Fahde, A. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114194 · Cited by 66 · see citing works
The effect of UV-filters on the viability of neuroblastoma (SH-SY5Y) cell line
Broniowska, Ż., Pomierny, B., Smaga, I., Filip, M., & Budziszewska, B. (2016) · NeuroToxicology · doi:10.1016/j.neuro.2016.03.003 · Cited by 64 · see citing works
Caruso, G., Pedà, C., Cappello, S., Leonardi, M., Ferla, R. L., Giudice, A. L., Maricchiolo, G., Rizzo, C., Maimone, G., Rappazzo, A. C., et al. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-018-2926-x · Cited by 62 · see citing works
First evaluation of neustonic microplastics in the Macaronesian region, NE Atlantic
Herrera, A., Raymond, E., Martínez, I., Álvarez, S., Canning‐Clode, J., Gestoso, I., Pham, C. K., Ríos, N., Rodríguez, Y., & Gómez, M. (2020) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2020.110999 · Cited by 62 · see citing works
Self-citationGatesoupe, F.-J., Huelvan, C., Bayon, N. L., Delliou, H. L., Madec, L., Mouchel, O., Quazuguel, P., Mazurais, D., & Zambonino‐Infante, J. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0885-2 · Cited by 55 · see citing works
Torrecillas, S., Terova, G., Makol, A., Serradell, A., Valdenegro, V., Gini, E., Izquierdo, M. S., Acosta, F., & Montero, D. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222063 · Cited by 51 · see citing works
Self-citationHenríquez‐Hernández, L. A., Montero, D., Camacho, M., Ginés, R., Boada, L. D., Ramírez, B., Valerón, P. F., Almeida‐González, M., Zumbado, M. L., Haroun, R. J., et al. (2016) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2016.12.107 · Cited by 48 · see citing works
Self-citationParma, L., Yúfera, M., Navarro-Guillén, C., et al. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.05.064 · Cited by 47 · see citing works
Ašmonaitė, G., Tivefälth, M., Westberg, E., Magnér, J., Backhaus, T., & Almroth, B. C. (2020) · Frontiers in Environmental Science · doi:10.3389/fenvs.2020.00087 · Cited by 46 · see citing works
Póvoa, T. F., Oliveira, E., Basílio‐de‐Oliveira, C. A., Nuovo, G. J., Chagas, V. L. A., Salomão, N. G., Mota, É. M., & Paes, M. V. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168973 · Cited by 43 · see citing works
Development of Marine Probiotics
Kim, S., Bhatnagar, I., & Kang, K. (2012) · Advances in food and nutrition research · doi:10.1016/b978-0-12-416003-3.00023-8 · Cited by 30 · see citing works
Chen, L., Jiang, Y., Liang, C. C., et al. (2019) · Microbiome · doi:10.1186/s40168-019-0765-8 · Cited by 29 · see citing works
Anna, J. S. D., Castro, J. M., Arias-Darraz, L., et al. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111394 · Cited by 29 · see citing works
Effects of organochlorine pesticides on interleukin secretion from lymphocytes
Beach, T. M., & Whalen, M. M. (2006) · Human & Experimental Toxicology · doi:10.1177/0960327106070072 · Cited by 20 · see citing works
Téllez‐Bañuelos, M. C., Haramati, J., Franco‐Topete, K., et al. (2016) · Journal of Immunotoxicology · doi:10.1080/1547691x.2016.1206998 · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Cocci, P., Gabrielli, S., Pastore, G., Minicucci, M., Mosconi, G., & Palermo, F. A. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.135813 · Cited by 58 · see citing works
Is Wild Marine Biota Affected by Microplastics?
Porcino, N., Bottari, T., & Mancuso, M. (2022) · Animals · doi:10.3390/ani13010147 · Cited by 55 · see citing works
“, organic contaminants and heavy metals) [26,27].”
- Authors
- Montero, D., Rimoldi, S., Torrecillas, S., Rapp, J., Moroni, F., Herrera, A., Gómez, M., Fernández-Montero, Á., & Terova, G.
- Affiliations
- Universidad de Las Palmas de Gran Canaria (ES)
- University of Insubria (IT)
- Corresponding author
- Terova, Genciana
- ORCID
- Venue
- Science of The Total Environment
- Publisher
- Elsevier BV
- Published
- 2022-01
- Volume
- 805
- Pages
- 150402
- ISSN
- 0048-9697 (ISSN-L)
- OpenAlex
- W3199849607
- Cited by
- 127
- References
- 108
- Citations by year
- 2026: 15 · 2025: 30 · 2024: 30 · 2023: 29 · 2022: 22 · 2021: 1
- FWCI
- 5.09
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- The Science of The Total Environment (publishedVersion)
- PubMed (publishedVersion)
- Acceda (Universidad de Las Palmas de Gran Canaria) (submittedVersion)
- IrInSubria (University of Insubria) (submittedVersion, cc-by)
- Funders
- European Commission (11.0661/2016/748064/SUB/ENV.C)
- University of Las Palmas de Gran Canaria
- Topics
- Physical Sciences › Environmental Science › Pollution › Microplastics and Plastic Pollution
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
- Keywords
- polypropylene microplastics, chemical contaminants, Dicentrarchus labrax, gut microbiota, intestinal inflammation, chlorpyrifos, benzophenone-3, endocrine disruptors, synergistic toxicity, gut dysbiosis, lactic acid bacteria, fish feed contamination, marine plastic pollution
- MeSH terms
- Gastrointestinal Microbiome, Microplastics, Animals, Bass, Environmental Pollutants, Plastics, Polypropylenes, Water Pollutants, Chemical, Ecosystem
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
