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Cited by 269

The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.

Biology of the Hair Follicle: The Basics

Krause, Karoline, Foitzik, Kerstin·2006·Seminars in Cutaneous Medicine and Surgery
DOI 10.1016/j.sder.2006.01.002
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Abstract

The mammalian hair follicle represents a unique, highly regenerative neuroectodermal-mesodermal interaction system that contains numerous stem cells. It is the only organ in the mammalian organism that undergoes life-long cycles of rapid growth (anagen), regression (catagen), and resting periods (telogen). These transformations are controlled by changes in the local signaling milieu, based on changes in expression/activity of a constantly growing number of cytokines, hormones, neurotransmitters, and their cognate receptors as well as of transcription factors and enzymes that have become recognized as key mediators of hair follicle cycling. Transplantation experiments have shown that the driving force of cycling, the "hair cycle clock," is located in the hair follicle itself. However, the exact underlying molecular mechanisms that drive this oscillator system remain unclear. These controls of hair follicle cycling are of great clinical interest because hair loss or unwanted hair growth largely reflect undesired changes in hair follicle cycling. To develop therapeutic agents for the management of these hair cycle abnormalities, it is critical to decipher and pharmacologically target the key molecular controls that underlie the enigmatic "hair cycle clock."

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Metadata

Authors
Krause, K., & Foitzik, K.
Venue
Seminars in Cutaneous Medicine and Surgery
Publisher
Frontline Medical Communications, Inc.
Published
2006-03
Volume
25
Issue
1
Pages
2-10
ISSN
1085-5629 (ISSN-L)
DOI
10.1016/j.sder.2006.01.002
OpenAlex
W2049949169
Cited by
269
References
98
FWCI
7.35
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Biology of the Hair Follicle: The Basics. https://app.cochat.ai/papers/10.1016/j.sder.2006.01.002
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Krause, K., & Foitzik, K. (2006). Biology of the Hair Follicle: The Basics. Seminars in Cutaneous Medicine and Surgery. https://doi.org/10.1016/j.sder.2006.01.002

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.