The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Metabolic Plasticity in Stem Cell Homeostasis and Differentiation
Open accessAbstract
Plasticity in energy metabolism allows stem cells to match the divergent demands of self-renewal and lineage specification. Beyond a role in energetic support, new evidence implicates nutrient-responsive metabolites as mediators of crosstalk between metabolic flux, cellular signaling, and epigenetic regulation of cell fate. Stem cell metabolism also offers a potential target for controlling tissue homeostasis and regeneration in aging and disease. In this Perspective, we cover recent progress establishing an emerging relationship between stem cell metabolism and cell fate control.
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Cites
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Cited by
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Stincone, A., Prigione, A., Cramer, T., Wamelink, M. M. C., Campbell, K., Cheung, E., Olin‐Sandoval, V., Grüning, N., Krüger, A., Tauqeer Alam, M., et al. (2015) · Biological Reviews · doi:10.1111/brv.12140 · Cited by 1,576
NAD + repletion improves mitochondrial and stem cell function and enhances life span in mice
Zhang, H., Ryu, D., Wu, Y., Gariani, K., Wang, X., Luan, P., D’Amico, D., Ropelle, E. R., Lutolf, M. P., Aebersold, R., et al. (2016) · Science · doi:10.1126/science.aaf2693 · Cited by 1,255
Stem cells and the impact of ROS signaling
Bigarella, C. L., Liang, R., & Ghaffari, S. (2014) · Development · doi:10.1242/dev.107086 · Cited by 632
A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging
Mohrin, M., Shin, J., Liu, Y., Brown, K., Luo, H., Xi, Y., Haynes, C. M., & Chen, D. (2015) · Science · doi:10.1126/science.aaa2361 · Cited by 490
Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways
Jia, D., Lu, M., Jung, K. H., Park, J. H., Yu, L., Onuchic, J. N., Kaipparettu, B. A., & Levine, H. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1816391116 · Cited by 336
Metadata
- Authors
- Folmes, C. D. L., Dzeja, P. P., Nelson, T. J., & Terzic, A.
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 11
- Issue
- 5
- Pages
- 596-606
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W1964324925
- Cited by
- 669
- References
- 24
- FWCI
- 12.63
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Folmes, C. D. L., Dzeja, P. P., Nelson, T. J., & Terzic, A. (2012). Metabolic Plasticity in Stem Cell Homeostasis and Differentiation. Cell Stem Cell. https://doi.org/10.1016/j.stem.2012.10.002
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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