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Mir-17∼92 Confers Motor Neuron Subtype Differential Resistance to ALS-Associated Degeneration

Tung, Ying-Tsen, Peng, Kuan-Chih, Chen, Yen-Chung, Yen, Ya-Ping, Chang, Mien, Thams, Sebastian, Chen, Jun-An·2019·Cell Stem Cell
DOI 10.1016/j.stem.2019.04.016
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  1. Amin, 2015, Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure, Science, 350, 1525, 10.1126/science.aad2509 · DOI · Paper page
  2. Bandyopadhyay, 2013, RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse, PLoS ONE, 8, e53575, 10.1371/journal.pone.0053575 · DOI
  3. Becker, 2017, Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice, Nature, 544, 367, 10.1038/nature22038 · DOI · Paper page
  4. Boulting, 2011, A functionally characterized test set of human induced pluripotent stem cells, Nat. Biotechnol., 29, 279, 10.1038/nbt.1783 · DOI
  5. Caballero-Hernandez, 2016, The ‘Omics’ of Amyotrophic Lateral Sclerosis, Trends Mol. Med., 22, 53, 10.1016/j.molmed.2015.11.001 · DOI
  6. Campos-Melo, 2013, Altered microRNA expression profile in Amyotrophic Lateral Sclerosis: a role in the regulation of NFL mRNA levels, Mol. Brain, 6, 26, 10.1186/1756-6606-6-26 · DOI
  7. Cantor, 2018, Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody, eLife, 7, 10.7554/eLife.34375 · DOI
  8. Capauto, 2018, A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons, Mol. Neurobiol., 55, 7635, 10.1007/s12035-018-0884-4 · DOI
  9. Cappellari, 1999, A tentative interpretation of electromyographic regional differences in bulbar- and limb-onset ALS, Neurology, 52, 644, 10.1212/WNL.52.3.644 · DOI
  10. Chakraborty, 2017, Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine, Mol. Ther. Nucleic Acids, 8, 132, 10.1016/j.omtn.2017.06.005 · DOI
  11. Chen, 2012, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation, Front. Neurosci., 6, 69, 10.3389/fnins.2012.00069 · DOI
  12. Chen, 2011, Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop, Neuron, 69, 721, 10.1016/j.neuron.2011.01.014 · DOI
  13. Chen, 2014, Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons, Cell Stem Cell, 14, 796, 10.1016/j.stem.2014.02.004 · DOI · Paper page
  14. Chiu, 1995, Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis, Mol. Cell. Neurosci., 6, 349, 10.1006/mcne.1995.1027 · DOI
  15. Chou, 2018, TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD, Nat. Neurosci., 21, 228, 10.1038/s41593-017-0047-3 · DOI
  16. Couillard-Després, 1998, Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase, Proc. Natl. Acad. Sci. USA, 95, 9626, 10.1073/pnas.95.16.9626 · DOI
  17. Davis-Dusenbery, 2014, How to make spinal motor neurons, Development, 141, 491, 10.1242/dev.097410 · DOI
  18. de Carvalho, 2008, Paraspinal and limb motor neuron involvement within homologous spinal segments in ALS, Clin. Neurophysiol., 119, 1607, 10.1016/j.clinph.2008.03.014 · DOI
  19. Di Giorgio, 2007, Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model, Nat. Neurosci., 10, 608, 10.1038/nn1885 · DOI · Paper page
  20. Di Giorgio, 2008, Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation, Cell Stem Cell, 3, 637, 10.1016/j.stem.2008.09.017 · DOI
  21. Dini Modigliani, 2014, An ALS-associated mutation in the FUS 3′-UTR disrupts a microRNA-FUS regulatory circuitry, Nat. Commun., 5, 4335, 10.1038/ncomms5335 · DOI
  22. Egawa, 2012, Drug screening for ALS using patient-specific induced pluripotent stem cells, Sci. Transl. Med., 4, 145ra104, 10.1126/scitranslmed.3004052 · DOI
  23. Eitan, 2016, Vulnerability of microRNA biogenesis in FTD-ALS, Brain Res., 1647, 105, 10.1016/j.brainres.2015.12.063 · DOI
  24. Emde, 2015, Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS, EMBO J., 34, 2633, 10.15252/embj.201490493 · DOI · Paper page
  25. Foust, 2013, Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS, Mol. Ther., 21, 2148, 10.1038/mt.2013.211 · DOI
  26. Gal, 2016, ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics, Acta Neuropathol., 132, 563, 10.1007/s00401-016-1601-x · DOI
  27. Gascon, 2014, The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders, J. Neurogenet., 28, 30, 10.3109/01677063.2013.876021 · DOI
  28. Goodall, 2013, Neuronal dark matter: the emerging role of microRNAs in neurodegeneration, Front. Cell. Neurosci., 7, 178, 10.3389/fncel.2013.00178 · DOI · Paper page
  29. Hamburger, 1951, A series of normal stages in the development of the chick embryo, J. Morphol., 88, 49, 10.1002/jmor.1050880104 · DOI
  30. Haramati, 2010, miRNA malfunction causes spinal motor neuron disease, Proc. Natl. Acad. Sci. USA, 107, 13111, 10.1073/pnas.1006151107 · DOI
  31. Hoye, 2018, Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis, Brain, 141, 2561
  32. Jung, 2014, Evolving Hox activity profiles govern diversity in locomotor systems, Dev. Cell, 29, 171, 10.1016/j.devcel.2014.03.008 · DOI
  33. Kanning, 2010, Motor neuron diversity in development and disease, Annu. Rev. Neurosci., 33, 409, 10.1146/annurev.neuro.051508.135722 · DOI
  34. Kaplan, 2014, Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration, Neuron, 81, 333, 10.1016/j.neuron.2013.12.009 · DOI
  35. Kawahara, 2012, TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes, Proc. Natl. Acad. Sci. USA, 109, 3347, 10.1073/pnas.1112427109 · DOI
  36. Kiskinis, 2014, Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1, Cell Stem Cell, 14, 781, 10.1016/j.stem.2014.03.004 · DOI · Paper page
  37. Kovanda, 2018, Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls, Sci. Rep., 8, 5609, 10.1038/s41598-018-23139-2 · DOI
  38. Kye, 2014, The role of miRNA in motor neuron disease, Front. Cell. Neurosci., 8, 15, 10.3389/fncel.2014.00015 · DOI
  39. Lalancette-Hebert, 2016, Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS, Proc. Natl. Acad. Sci. USA, 113, E8316, 10.1073/pnas.1605210113 · DOI
  40. Li, 2017, MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord, Nat. Commun., 8, 14685, 10.1038/ncomms14685 · DOI
  41. Maury, 2014, Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes, Nat. Biotechnol., 33, 89, 10.1038/nbt.3049 · DOI
  42. McGoldrick, 2013, Rodent models of amyotrophic lateral sclerosis, Biochim. Biophys. Acta, 1832, 1421, 10.1016/j.bbadis.2013.03.012 · DOI
  43. Miller, 2012, Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND), Cochrane Database Syst. Rev., 3, CD001447
  44. Morikawa, 2009, Detailed expression pattern of Foxp1 and its possible roles in neurons of the spinal cord during embryogenesis, Dev. Neurosci., 31, 511, 10.1159/000243715 · DOI
  45. Morlando, 2012, FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment, EMBO J., 31, 4502, 10.1038/emboj.2012.319 · DOI
  46. Nepal, 2009, Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas, Proc. Natl. Acad. Sci. USA, 106, 18698, 10.1073/pnas.0905965106 · DOI
  47. Olive, 2013, A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis, eLife, 2, e00822, 10.7554/eLife.00822 · DOI
  48. Peljto, 2010, Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation, Cell Stem Cell, 7, 355, 10.1016/j.stem.2010.07.013 · DOI
  49. Philips, 2014, Glial cells in amyotrophic lateral sclerosis, Exp. Neurol., 262, 111, 10.1016/j.expneurol.2014.05.015 · DOI
  50. Pun, 2006, Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF, Nat. Neurosci., 9, 408, 10.1038/nn1653 · DOI
  51. Rocha, 2013, Early changes of neuromuscular transmission in the SOD1(G93A) mice model of ALS start long before motor symptoms onset, PLoS ONE, 8, e73846, 10.1371/journal.pone.0073846 · DOI
  52. Samaranch, 2017, MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain, Gene Ther., 24, 253, 10.1038/gt.2017.14 · DOI
  53. Sekar, 2018, Elevated nuclear phosphatase and tensin homolog (PTEN) and altered insulin signaling in substantia nigral region of patients with Parkinson’s disease, Neurosci. Lett., 666, 139, 10.1016/j.neulet.2017.12.049 · DOI
  54. Shi, 2018, Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons, Nat. Med., 24, 313, 10.1038/nm.4490 · DOI · Paper page
  55. Stopford, 2017, C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten, Hum. Mol. Genet., 26, 1133, 10.1093/hmg/ddx022 · DOI
  56. Swinnen, 2014, The phenotypic variability of amyotrophic lateral sclerosis, Nat. Rev. Neurol., 10, 661, 10.1038/nrneurol.2014.184 · DOI
  57. Taylor, 2016, Decoding ALS: from genes to mechanism, Nature, 539, 197, 10.1038/nature20413 · DOI
  58. Tung, 2015, Mir-17∼92 Governs Motor Neuron Subtype Survival by Mediating Nuclear PTEN, Cell Rep., 11, 1305, 10.1016/j.celrep.2015.04.050 · DOI
  59. Valdez, 2014, The role of muscle microRNAs in repairing the neuromuscular junction, PLoS ONE, 9, e93140, 10.1371/journal.pone.0093140 · DOI
  60. Wang, 2014, Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis, Hum. Mol. Genet., 23, 668, 10.1093/hmg/ddt454 · DOI
  61. Williams, 2009, MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice, Science, 326, 1549, 10.1126/science.1181046 · DOI · Paper page
  62. Wootz, 2013, Alterations in the motor neuron-renshaw cell circuit in the Sod1(G93A) mouse model, J. Comp. Neurol., 521, 1449, 10.1002/cne.23266 · DOI
  63. Writing, 2017, Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial, Lancet Neurol., 16, 505, 10.1016/S1474-4422(17)30115-1 · DOI
  64. Xia, 2006, Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo, Neurobiol. Dis., 23, 578, 10.1016/j.nbd.2006.04.019 · DOI
  65. Xiao, 2008, Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes, Nat. Immunol., 9, 405, 10.1038/ni1575 · DOI
  66. Yamashita, 2013, Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons, EMBO Mol. Med., 5, 1710, 10.1002/emmm.201302935 · DOI
  67. Yang, 2013, A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS, Cell Stem Cell, 12, 713, 10.1016/j.stem.2013.04.003 · DOI
  68. Zhang, 2013, Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries, J. Neurosci., 33, 7997, 10.1523/JNEUROSCI.5661-12.2013 · DOI
  69. Zhang, 2013, The MicroRNA-17-92 cluster enhances axonal outgrowth in embryonic cortical neurons, J. Neurosci., 33, 6885, 10.1523/JNEUROSCI.5180-12.2013 · DOI
  70. Zhang, 2015, The C9orf72 repeat expansion disrupts nucleocytoplasmic transport, Nature, 525, 56, 10.1038/nature14973 · DOI · Paper page
  71. Zheng, 2012, Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN, J. Cell Sci., 125, 1556, 10.1242/jcs.095729 · DOI

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Metadata

Authors
Tung, Y.-T., Peng, K.-C., Chen, Y.-C., Yen, Y.-P., Chang, M., Thams, S., & Chen, J.-A.
ORCID
Chen, Jun-An
Venue
Cell Stem Cell
Publisher
Elsevier BV
Published
2019-08
Volume
25
Issue
2
Pages
193-209.e7
ISSN
1934-5909
DOI
10.1016/j.stem.2019.04.016
Cited by
53
References
10
Language
en
Licence
Funders
  • Academia Sinica (AS-104-TP-B09)
  • National Health Research Institutes (NHRI-EX108-10831NI, 62/652,127)
  • Taiwan Mouse Clinic
  • Columbia University
  • Ministry of Science and Technology, Taiwan (105-2321-B-001-068-MY3)

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