The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism

The gut microbiota as an environmental factor that regulates fat storage

Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245 · see citing works

Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity

Browning, J. D., Szczepaniak, L. S., Dobbins, R., Nuremberg, P., Horton, J. D., Cohen, J. C., Grundy, S. M., & Hobbs, H. H. (2004) · Hepatology · doi:10.1002/hep.20466 · Cited by 3,664 · see citing works

THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUDY: DESIGN AND OBJECTIVES

THE ARIC INVESTIGATORS (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115184 · Cited by 3,491 · see citing works

Untitled work

(1989) · PubMed · Cited by 3,139 · see citing works

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

Bäckhed, F., Manchester, J. K., Semenkovich, C. F., & Gordon, J. I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605374104 · Cited by 2,615 · see citing works

PPARs and the complex journey to obesity

Evans, R. M., Barish, G. D., & Wang, Y.-X. (2004) · Nature Medicine · doi:10.1038/nm1025 · Cited by 1,621 · see citing works

Prox1 Function Is Required for the Development of the Murine Lymphatic System

Wigle, J. T., & Oliver, G. C. (1999) · Cell · doi:10.1016/s0092-8674(00)81511-1 · Cited by 1,581 · see citing works

Coiled coils: a highly versatile protein folding motif.

Burkhard, P., Stetefeld, J., & Strelkov, S. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(00)01898-5 · Cited by 1,055 · see citing works

Sorting out the roles of PPAR  in energy metabolism and vascular homeostasis

Lefebvre, P. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27989 · Cited by 962 · see citing works

Epidemiologic and economic consequences of the global epidemics of obesity and diabetes

Yach, D., Stückler, D., & Brownell, K. D. (2006) · Nature Medicine · doi:10.1038/nm0106-62 · Cited by 856 · see citing works

HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation

Gordan, J. D., Thompson, C. B., & Simon, M. C. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.07.006 · Cited by 806 · see citing works

Hypoxia: A key regulator of angiogenesis in cancer

Liao, D., & Johnson, R. S. (2007) · Cancer and Metastasis Reviews · doi:10.1007/s10555-007-9066-y · Cited by 720 · see citing works

Retinal angiogenesis in development and disease

Gariano, R. F., & Gardner, T. W. (2005) · Nature · doi:10.1038/nature04482 · Cited by 707 · see citing works

Overweight and Obesity: Prevalence, Consequences, and Causes of a Growing Public Health Problem

Wyatt, S. B., Winters, K. P., & Dubbert, P. M. (2006) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200604000-00002 · Cited by 697 · see citing works

Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene

Kersten, S., Mandard, S., Tan, N. S., Escher, P., METZGER, D., Chambon, P., Gonzalez, F. J., Desvergne, B., & Wahli, W. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004029200 · Cited by 560 · see citing works

The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health

Victor, R. G., Haley, R. W., Willett, D. L., Peshock, R. M., Vaeth, P. C., Leonard, D. S., Basit, M. A., Cooper, R., Iannacchione, V. G., Visscher, W. A., et al. (2004) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.02.058 · Cited by 526 · see citing works

Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL

Romeo, S., Pennacchio, L. A., Fu, Y., Boerwinkle, E., Tybjaerg-Hansen, A., Hobbs, H. H., & Cohen, J. C. (2007) · Nature Genetics · doi:10.1038/ng1984 · Cited by 511 · see citing works

Peroxisome Proliferator-activated Receptor γ Ligands Are Potent Inhibitors of Angiogenesis in Vitro and in Vivo

Xin, X., Yang, S., Kowalski, J., & Gerritsen, M. E. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.13.9116 · Cited by 508 · see citing works

The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity

Mandard, S., Zandbergen, F., van Straten, E., Wahli, W., Kuipers, F., Müller, M., & Kersten, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m506519200 · Cited by 433 · see citing works

Transgenic Angiopoietin-Like (Angptl)4 Overexpression and Targeted Disruption of Angptl4 and Angptl3: Regulation of Triglyceride Metabolism

Köster, A., Chao, Y. B., Mosior, M., Ford, A., Gonzalez-DeWhitt, P. A., Hale, J. E., Li, D., Qiu, Y., Fraser, C. C., Yang, D. D., et al. (2005) · Endocrinology · doi:10.1210/en.2005-0476 · Cited by 427 · see citing works

Angptl3 regulates lipid metabolism in mice

Koishi, R., Ando, Y., Ono, M., Shimamura, M., Yasumo, H., Fujiwara, T., Horikoshi, H., & Furukawa, H. (2002) · Nature Genetics · doi:10.1038/ng814 · Cited by 420 · see citing works

Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue

Sukonina, V., Lõokene, A., Olivecrona, T., & Olivecrona, G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604026103 · Cited by 402 · see citing works

Peroxisome Proliferator-Activated Receptor γ Target Gene Encoding a Novel Angiopoietin-Related Protein Associated with Adipose Differentiation

Yoon, J. C., Chickering, T. W., Rosen, E. D., Dussault, B. J., Qin, Y., Soukas, A. A., Friedman, J. M., Holmes, W. E., & Spiegelman, B. M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.14.5343-5349.2000 · Cited by 399 · see citing works

ANGPTL3 Decreases Very Low Density Lipoprotein Triglyceride Clearance by Inhibition of Lipoprotein Lipase

Shimizugawa, T., Ono, M., Shimamura, M., Yoshida, K., Ando, Y., Koishi, R., Ueda, K., Inaba, T., Minekura, H., Kohama, T., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203215200 · Cited by 370 · see citing works

Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase

Yoshida, K., Shimizugawa, T., Ono, M., & Furukawa, H. (2002) · Journal of Lipid Research · doi:10.1194/jlr.c200010-jlr200 · Cited by 368 · see citing works

Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells

Zhang, C. C., Kaba, M., Ge, G., Xie, K. T., Tong, W., Hug, C., & Lodish, H. F. (2006) · Nature Medicine · doi:10.1038/nm1342 · Cited by 367 · see citing works

PPARγ Activation in Human Endothelial Cells Increases Plasminogen Activator Inhibitor Type-1 Expression

Marx, N., Bourcier, T., Sukhova, G. K., Libby, P., & Plutzky, J. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.3.546 · Cited by 362 · see citing works

Mortality and Cardiac and Vascular Outcomes in Extremely Obese Women

McTigue, K. M., Larson, J. C., Valoski, A. M., Burke, G. L., Kotchen, J. M., Lewis, C. E., Stefanick, M. L., Horn, L. V., & Kuller, L. H. (2006) · JAMA · doi:10.1001/jama.296.1.79 · Cited by 357 · see citing works

Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma

Jan, S. L., Amy, C., Cazes, A., Monnot, C., Lamandé, N., Favier, J., Philippe, J., Sibony, M., Gasc, J., Corvol, P. L., et al. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64285-x · Cited by 342 · see citing works

Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice

Xu, A., Lam, M. C., Chan, K. W., Wang, Y., Zhang, J., Hoo, R. L. C., Xu, J. Y., Chen, B., Chow, W.-S., Tso, A. W. K., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408452102 · Cited by 315 · see citing works

Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1α Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene Expression

Peng, X.-H., Karna, P., Cao, Z., Jiang, B., Zhou, M., & Yang, L. P. H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603414200 · Cited by 298 · see citing works

Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol Through Suppression of Endothelial Lipase

Shimamura, M., Matsuda, M., Yasumo, H., Okazaki, M., Fujimoto, K., Kono, K., Shimizugawa, T., Ando, Y., Koishi, R., Kohama, T., et al. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000252827.51626.89 · Cited by 297 · see citing works

Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis

Kim, I., Kim, H.-G., Kim, H., Kim, H.-H., Park, S. K., Uhm, C.-S., Lee, Z. H., & Koh, G. Y. (2000) · Biochemical Journal · doi:10.1042/bj3460603 · Cited by 284 · see citing works

Regulation of Angiogenesis by Hypoxia and Hypoxia‐Inducible Factors

Hickey, M. M., & Simon, M. C. (2006) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(06)76007-0 · Cited by 268 · see citing works

The Direct Peroxisome Proliferator-activated Receptor Target Fasting-induced Adipose Factor (FIAF/PGAR/ANGPTL4) Is Present in Blood Plasma as a Truncated Protein That Is Increased by Fenofibrate Treatment

Mandard, S., Zandbergen, F. J., Tan, N. S., Escher, P., Patsouris, D., Köenig, W., Kleemann, R., Bakker, A. H. F., Veenman, F., Wahli, W., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403058200 · Cited by 267 · see citing works

Direct Cell Adhesion to the Angiopoietins Mediated by Integrins

Carlson, T. R., Feng, Y., Maisonpierre, P. C., Mrksich, M., & Morla, A. O. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100282200 · Cited by 265 · see citing works

ANGPTL3 Stimulates Endothelial Cell Adhesion and Migration via Integrin αvβ3 and Induces Blood Vessel Formation in Vivo

Camenisch, G., Pisabarro, M. T., Sherman, D. A., Kowalski, J., Nagel, M., Hass, P., Xie, M.-H., Gurney, A. L., Bodary, S. C., Liang, X. H., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109768200 · Cited by 253 · see citing works

COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity

Cho, C., Kammerer, R. A., Lee, H. J., Steinmetz, M. O., Ryu, Y. S., Lee, S. H., Yasunaga, K., Kim, K.-T., Kim, I., Choi, H.-H., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307574101 · Cited by 253 · see citing works

Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering

Davis, S., Papadopoulos, N., Aldrich, T. H., Maisonpierre, P. C., Huang, T., Kovac, L., Xu, A., Leidich, R., Radziejewska, E., Rafique, A., et al. (2003) · Nature Structural Biology · doi:10.1038/nsb880 · Cited by 234 · see citing works

The burden of overweight and obesity in the Asia–Pacific region

Asia Pacific Cohort Studies Collaboration (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00292.x · Cited by 220 · see citing works

Angiopoietin-related growth factor antagonizes obesity and insulin resistance

Oike, Y., Akao, M., Yasunaga, K., Yamauchi, T., Morisada, T., Ito, Y., Urano, T., Kimura, Y., Kubota, Y., Maekawa, H., et al. (2005) · Nature Medicine · doi:10.1038/nm1214 · Cited by 219 · see citing works

Molecular Cloning, Expression, and Characterization of Angiopoietin-related Protein

Kim, I., Moon, S.-O., Koh, K. N., Kim, H., Uhm, C.-S., Kwak, H. J., Kim, N.-G., & Koh, G. Y. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.26523 · Cited by 212 · see citing works

Protein Region Important for Regulation of Lipid Metabolism in Angiopoietin-like 3 (ANGPTL3)

Ono, M., Shimizugawa, T., Shimamura, M., Yoshida, K., Noji-Sakikawa, C., Ando, Y., Koishi, R., & Furukawa, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302861200 · Cited by 207 · see citing works

Extracellular Matrix–Bound Angiopoietin-Like 4 Inhibits Endothelial Cell Adhesion, Migration, and Sprouting and Alters Actin Cytoskeleton

Cazes, A., Galaup, A., Chomel, C., Bignon, M., Bréchot, N., Jan, S. L., Weber, H., Corvol, P. L., Muller, L., Germain, S., et al. (2006) · Circulation Research · doi:10.1161/01.res.0000250758.63358.91 · Cited by 198 · see citing works

Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4.

Ito, Y., Oike, Y., Yasunaga, K., Hamada, K., Miyata, K., Matsumoto, S.-I., Sugano, S., Tanihara, H., Masuho, Y., & Suda, T. (2003) · PubMed · Cited by 196 · see citing works

Angptl4 Upregulates Cholesterol Synthesis in Liver via Inhibition of LPL- and HL-Dependent Hepatic Cholesterol Uptake

Lichtenstein, L., Berbée, J. F. P., van Dijk, S. J., van Dijk, K. W., Bensadoun, A., Kema, I. P., Voshol, P. J., Müller, M. M., Rensen, P. C. N., & Kersten, S. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.151894 · Cited by 196 · see citing works

Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice

Desai, U. S., Lee, E.-C., Chung, K., Gao, C., Gay, J. P., Key, B., Hansen, G. M., Machajewski, D., Platt, K. A., Sands, A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705041104 · Cited by 192 · see citing works

Angiopoietin-Related/Angiopoietin-Like Proteins Regulate Angiogenesis

Oike, Y., Yasunaga, K., & Suda, T. (2004) · International Journal of Hematology · doi:10.1532/ijh97.04034 · Cited by 160 · see citing works

Oligomerization and Regulated Proteolytic Processing of Angiopoietin-like Protein 4

Ge, H., Yang, G., Huang, L., Motola, D., Pourbahrami, T., & Li, C. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m307583200 · Cited by 156 · see citing works

Angiopoietin-1 and -2 Coiled Coil Domains Mediate Distinct Homo-oligomerization Patterns, but Fibrinogen-like Domains Mediate Ligand Activity

Procopio, W. N., Pelavin, P. I., Lee, W. M. F., & Yeilding, N. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.30196 · Cited by 156 · see citing works

Differential regulation and properties of angiopoietin-like proteins 3 and 4

Ge, H., Cha, J.-Y., Gopal, H., Harp, C. T., Yu, X., Repa, J. J., & Li, C. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500005-jlr200 · Cited by 153 · see citing works

Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy

Oike, Y., Akao, M., Kubota, Y., & Suda, T. (2005) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2005.08.002 · Cited by 140 · see citing works

Angiopoietin-like Protein 3 Mediates Hypertriglyceridemia Induced by the Liver X Receptor

Inaba, T., Matsuda, M., Shimamura, M., Takei, N., Terasaka, N., Ando, Y., Yasumo, H., Koishi, R., Makishima, M., & Shimomura, I. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m213202200 · Cited by 138 · see citing works

Retinopathy Is Reduced during Experimental Diabetes in a Mouse Model of Outer Retinal Degeneration

de Gooyer, T. E., Stevenson, K. A., Humphries, P., Simpson, D. A. C., Gardiner, T. A., & Stitt, A. W. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-0647 · Cited by 136 · see citing works

PPARγ regulates the function of human dendritic cells primarily by altering lipid metabolism

Szatmári, I., Törőcsik, D., Agostini, M., Nagy, T., Gurnell, M., Barta, E., Chatterjee, K., & Nagy, L. (2007) · Blood · doi:10.1182/blood-2007-06-096222 · Cited by 133 · see citing works

Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration

Oike, Y., Yasunaga, K., Ito, Y., Matsumoto, S.-I., Maekawa, H., Morisada, T., Arai, F., Nakagata, N., Takeya, M., Masuho, Y., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1531901100 · Cited by 130 · see citing works

Regulation of the angiopoietin-like protein 3 gene by LXR

Kaplan, R. A., Zhang, T., Hernandez, M., Gan, F. X., Wright, S. D., Waters, M. G., & Cai, T. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200367-jlr200 · Cited by 127 · see citing works

Hepatic Proprotein Convertases Modulate HDL Metabolism

Jin, W., Wang, X., Millar, J. S., Quertermous, T., Rothblat, G. H., Glick, J. M., & Rader, D. J. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.07.009 · Cited by 126 · see citing works

Regulation of lipid metabolism via angiopoietin-like proteins

Kersten, S. (2005) · Biochemical Society Transactions · doi:10.1042/bst20051059 · Cited by 123 · see citing works

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

Bäckhed, F., Crawford, P. A., O’Donnell, D., & Gordon, J. I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605957104 · Cited by 117 · see citing works

Angiopoietin-related growth factor (AGF) promotes angiogenesis

Oike, Y., Ito, Y., Maekawa, H., Morisada, T., Kubota, Y., Akao, M., Urano, T., Yasunaga, K., & Suda, T. (2004) · Blood · doi:10.1182/blood-2003-04-1272 · Cited by 116 · see citing works

The Copenhagen City Heart Study : Østerbroundersøgelsen : tables with data from the third examination 1991-1994

Schnohr, P. (2001) · European Heart Journal Supplements · Cited by 116 · see citing works

Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4

Ge, H., Yang, G., Yu, X., Pourbahrami, T., & Li, C. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400138-jlr200 · Cited by 115 · see citing works

Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes

Shimamura, M., Matsuda, M., Kobayashi, S., Ando, Y., Ono, M., Koishi, R., Furukawa, H., Makishima, M., & Shimomura, I. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)03058-9 · Cited by 112 · see citing works

Angptl3-null Mice Show Low Plasma Lipid Concentrations by Enhanced Lipoprotein Lipase Activity

FUJIMOTO, K., KOISHI, R., SHIMIZUGAWA, T., & ANDO, Y. (2006) · Experimental Animals · doi:10.1538/expanim.55.27 · Cited by 104 · see citing works

Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development

Kubota, Y., Oike, Y., Satoh, S., Tabata, Y., Niikura, Y., Morisada, T., Akao, M., Urano, T., Ito, Y., Miyamoto, T. K., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501902102 · Cited by 104 · see citing works

A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice

Ando, Y., Shimizugawa, T., Takeshita, S., Ono, M., Shimamura, M., Koishi, R., & Furukawa, H. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m300031-jlr200 · Cited by 101 · see citing works

Peroxisome Proliferator-activated Receptor β/δ Regulates Very Low Density Lipoprotein Production and Catabolism in Mice on a Western Diet

Akiyama, T. E., Lambert, G., Nicol, C. J., Matsusue, K., Peters, J. M., Brewer, H. B., & Gonzalez, F. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312802200 · Cited by 97 · see citing works

Fenofibrate inhibits angiogenesis in vitro and in vivo

Pille, J., Varet, J., Vincent, L., Mirshahi, P., Legrand, E., Opolon, P., Mishal, Z., Soria, J., Li, H., & Soria, C. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2322-6 · Cited by 94 · see citing works

Coiled‐coil proteins associated with type III secretion systems: a versatile domain revisited

Delahay, R. M., & Frankel, G. M. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03083.x · Cited by 90 · see citing works

ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states

Inukai, K., Nakashima, Y., Watanabe, M., Kurihara, S., Awata, T., Katagiri, H., Oka, Y., & Katayama, S. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.03.151 · Cited by 82 · see citing works

Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin‐3

Kim, I., Kwak, H. J., Ahn, J. E., So, J.-N., Liu, M., Koh, K. N., & Koh, G. Y. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00008-3 · Cited by 79 · see citing works

Leptin and insulin down-regulate angiopoietin-like protein 3, a plasma triglyceride-increasing factor

Shimamura, M., Matsuda, M., Ando, Y., Koishi, R., Yasumo, H., Furukawa, H., & Shimomura, I. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.08.024 · Cited by 78 · see citing works

Angioarrestin: an antiangiogenic protein with tumor-inhibiting properties.

Dhanabal, M., LaRochelle, W. J., Jeffers, M., Herrmann, J. L., Rastelli, L., McDonald, W. F., Chillakuru, R. A., Yang, M., Boldog, F. L., Padigaru, M., et al. (2002) · PubMed · Cited by 78 · see citing works

Implications of Cardiac Risk and Low-Density Lipoprotein Cholesterol Distributions in the United States for the Diagnosis and Treatment of Dyslipidemia

Keevil, J. G., Cullen, M. W., Gangnon, R. E., McBride, P. E., & Stein, J. H. (2007) · Circulation · doi:10.1161/circulationaha.106.645473 · Cited by 76 · see citing works

The Lipoprotein Lipase Inhibitor ANGPTL3 Is Negatively Regulated by Thyroid Hormone

Fugier, C., Tousaint, J.-J., Prieur, X., Plateroti, M., Samarut, J., & Delerive, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512554200 · Cited by 74 · see citing works

Oncogenes and tumor angiogenesis

Rak, J. W., & Yu, J. (2004) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2003.09.014 · Cited by 72 · see citing works

Transcription of the Vascular Endothelial Growth Factor Gene in Macrophages Is Regulated by Liver X Receptors

Walczak, R., Joseph, S. B., Laffitte, B. A., Castrillo, A., Pei, L., & Tontonoz, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310587200 · Cited by 71 · see citing works

The Association of Initiation Factor 4F with Poly(A)-binding Protein Is Enhanced in Serum-stimulated Xenopus Kidney Cells

Fraser, C. S., Pain, V. M., & Morley, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.1.196 · Cited by 62 · see citing works

Association between Plasma Angiopoietin-Like Protein 3 and Arterial Wall Thickness in Healthy Subjects

Hatsuda, S., Shoji, T., Shinohara, K., Kimoto, E., Mori, K., Fukumoto, S., Koyama, H., Emoto, M., & Nishizawà, Y. (2006) · Journal of Vascular Research · doi:10.1159/000098153 · Cited by 60 · see citing works

Comparative integromics on Angiopoietin family members

Katoh, Y., & Katoh, M. (2006) · International Journal of Molecular Medicine · doi:10.3892/ijmm.17.6.1145 · Cited by 60 · see citing works

Overexpression of Angiopoietin-Like Protein 4 Alters Mitochondria Activities and Modulates Methionine Metabolic Cycle in the Liver Tissues of db/db Diabetic Mice

Wang, Y., Lam, K. S. L., Lam, J. B. B., Lam, M. C., Leung, P. T. Y., Zhou, M., & Xu, A. (2007) · Molecular Endocrinology · doi:10.1210/me.2006-0249 · Cited by 48 · see citing works

Angiopoietin-Related Growth Factor Suppresses Gluconeogenesis through the Akt/Forkhead Box Class O1-Dependent Pathway in Hepatocytes

Kitazawa, M., Ohizumi, Y., Oike, Y., Hishinuma, T., & Hashimoto, S. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.127530 · Cited by 44 · see citing works

Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans

Korstanje, R., Eriksson, P. O., Samnegård, A., Olsson, P. G., Forsman‐Semb, K., Sen, Ś., Churchill, G. A., Rollins, J. A., Harris, S. J., Hamsten, A., et al. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.08.006 · Cited by 43 · see citing works

Isolation and expression patterns of genes for three angiopoietin-like proteins, Angptl1, 2 and 6 in zebrafish

Kubota, Y., Oike, Y., Satoh, S., Tabata, Y., Niikura, Y., Morisada, T., Akao, M., Urano, T., Ito, Y., Miyamoto, T. K., et al. (2005) · Gene Expression Patterns · doi:10.1016/j.modgep.2005.02.006 · Cited by 40 · see citing works

Identification of a novel human angiopoietin-like gene expressed mainly in heart

Zeng, L., Dai, J., Ying, K., Zhao, E., Jin, W., Ye, Y., Dai, J., Xu, J., Xie, Y., & Mao, Y. (2003) · Journal of Human Genetics · doi:10.1007/s100380300025 · Cited by 36 · see citing works

Identification of a novel human doublecortin-domain-containing gene (DCDC1) expressed mainly in testis

Zeng, L., Gu, S., Li, Y., Zhao, E., Xu, J., Ye, X., Wu, Q., Wang, L., Xie, Y., & Mao, Y. (2003) · Journal of Human Genetics · doi:10.1007/s10038-003-0033-3 · Cited by 35 · see citing works

Fasting-induced adipose factor/angiopoietin–like protein 4: a potential target for dyslipidemia?

Zandbergen, F. J., van Dijk, S. J., Müller, M. M., & Kersten, S. (2006) · Future Lipidology · doi:10.2217/17460875.1.2.227 · Cited by 33 · see citing works

Angiopoietin‐like protein 1 expression is related to intermuscular connective tissue and cartilage development

Lai, D., Tu, Y., Hsieh, Y., Hsu, W., Lee, C., Cheng, W., Hsieh, F.-J., & Li, H. (2007) · Developmental Dynamics · doi:10.1002/dvdy.21262 · Cited by 9 · see citing works

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

Augustin, H. G., Koh, G. Y., Thurston, G., & Alitalo, K. K. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2639 · Cited by 1,460 · see citing works

Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance

Tabata, M., Kadomatsu, T., Fukuhara, S., Miyata, K., Ito, Y., Endo, M., Urano, T., Zhu, H. J., Tsukano, H., Tazume, H., et al. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.08.003 · Cited by 363 · see citing works

Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential

Lopatina, T., Bruno, S., Tetta, C., Kalinina, N., Porta, M., & Camussi, G. (2014) · Cell Communication and Signaling · doi:10.1186/1478-811x-12-26 · Cited by 308 · see citing works

A TAZ–ANGPTL4–NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer

Yang, W., Huang, Z., Wu, J., Ding, C. C., Murphy, S. K., & Chi, J. (2019) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-19-0691 · Cited by 302 · see citing works

Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism

Ren, G., Kim, J. Y., & Smas, C. M. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00084.2012 · Cited by 299 · see citing works

Inhibitory receptors bind Angptls and support blood stem cells and leukemia development

Zheng, J., Umikawa, M., Cui, C., Li, J., Chen, X., Zhang, C.-Z., Hyunh, H., Kang, X., Silvany, R., Wan, X., et al. (2012) · Nature · doi:10.1038/nature11095 · Cited by 267 · see citing works

Lipid Metabolism During Pregnancy and its Implications for Fetal Growth

Herrera, E., & Ortega, H. (2014) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201015666140330192345 · Cited by 277 · see citing works

Hepatokines and metabolism: Deciphering communication from the liver

Jensen-Cody, S. O., & Potthoff, M. J. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101138 · Cited by 252 · see citing works

Triglyceride lpases and atherosclerosis

Olivecrona, G., & Olivecrona, T. (1995) · Current Opinion in Lipidology · doi:10.1097/00041433-199510000-00009 · Cited by 238 · see citing works

Apolipoprotein C-II: new findings related to genetics, biochemistry, and role in triglyceride metabolism

Wolska, A., Dunbar, R. L., Freeman, L. A., Ueda, M., Amar, M. J., Sviridov, D. O., & Remaley, A. T. (2017) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2017.10.025 · Cited by 231 · see citing works

Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer

Carbone, C., Piro, G., Merz, V., Simionato, F., Santoro, R., Zecchetto, C., Tortora, G., & Melisi, D. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020431 · Cited by 217 · see citing works

Role of hepatic resident and infiltrating macrophages in liver repair after acute injury

You, Q., Holt, M. R., Yin, H., Li, G., Hu, C., & Ju, C. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.07.006 · Cited by 204 · see citing works

Emerging Roles of Angiopoietin-like 4 in Human Cancer

Tan, M., Teo, Z., Sng, M. K., Zhu, P., & Tan, N. S. (2012) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-11-0519 · Cited by 197 · see citing works

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway

Paglia, L. L., Listì, A., Caruso, S., Amodeo, V., Passiglia, F., Bazan, V., & Fanale, D. (2017) · PPAR Research · doi:10.1155/2017/8187235 · Cited by 174 · see citing works

Therapeutic application of anti-angiogenic nanomaterials in cancers

Mukherjee, S., & Patra, C. R. (2016) · Nanoscale · doi:10.1039/c5nr07887c · Cited by 170 · see citing works

Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4

Xin, X., Rodrigues, M. W., Umapathi, M., Kashiwabuchi, F., Ma, T., Babapoor-Farrokhran, S., Wang, S., Hu, J., Bhutto, I. A., Welsbie, D. S., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1217091110 · Cited by 165 · see citing works

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

Koliwad, S. K., Kuo, T., Shipp, L. E., Gray, N. E., Backhed, F., So, A. Y.-L., Farese, R. V., & Wang, J.-C. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.025452 · Cited by 164 · see citing works

Diverse roles of ANGPTL2 in physiology and pathophysiology

Kadomatsu, T., Endo, M., Miyata, K., & Oike, Y. (2014) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2014.03.012 · Cited by 160 · see citing works

ANGPTL4: a multifunctional protein involved in metabolism and vascular homeostasis

Fernandez-Hernando, C. F., & Suárez, Y. (2020) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000580 · Cited by 162 · see citing works

Retinal and choroidal angiogenesis: a review of new targets

Cabral, T., Mello, L. G. M., de Lima, L. H. S. G., Polido, J. G. F., Regatieri, C. V., Belfort, R., & Mahajan, V. B. (2017) · International Journal of Retina and Vitreous · doi:10.1186/s40942-017-0084-9 · Cited by 148 · see citing works

Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8

Sylvers-Davie, K. L., & Davies, B. S. J. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00195.2021 · Cited by 149 · see citing works

Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases

Kadomatsu, T., Tabata, M., & Oike, Y. (2010) · FEBS Journal · doi:10.1111/j.1742-4658.2010.07979.x · Cited by 141 · see citing works

The role of ANGPTL3 in controlling lipoprotein metabolism

Tikka, A., & Jauhiainen, M. (2016) · Endocrine · doi:10.1007/s12020-015-0838-9 · Cited by 131 · see citing works

Urine proteomics for profiling of human disease using high accuracy mass spectrometry

Kentsis, A., Monigatti, F., Dorff, K. C., Campagne, F., Bachur, R. G., & Steen, H. (2009) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200900008 · Cited by 127 · see citing works

The Secreted Protein ANGPTL2 Promotes Metastasis of Osteosarcoma Cells Through Integrin α 5 β 1 , p38 MAPK, and Matrix Metalloproteinases

Odagiri, H., Kadomatsu, T., Endo, M., Masuda, T., Morioka, M. S., Fukuhara, S., Miyamoto, T. K., Kobayashi, E., Miyata, K., Aoi, J., et al. (2014) · Science Signaling · doi:10.1126/scisignal.2004612 · Cited by 127 · see citing works

The acute phase response stimulates the expression of angiopoietin like protein 4

Lü, B., Moser, A. H., Shigenaga, J. K., Grünfeld, C., & Feingold, K. R. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.12.145 · Cited by 116 · see citing works

Hypoxia Promotes Efficient Differentiation of Human Embryonic Stem Cells to Functional Endothelium

Prado‐Lòpez, S., Conesa, A., Armiñán, A., Martínez‐Losa, M., Escobedo‐Lucea, C., Gandía, C., Tarazona, S., Melguizo‐Sanchis, D., Blesa, D., Montaner, D. A., et al. (2010) · Stem Cells · doi:10.1002/stem.295 · Cited by 115 · see citing works

A motif in LILRB2 critical for Angptl2 binding and activation

Deng, M., Lu, Z., Zheng, J., Wan, X., Chen, X., Hirayasu, K., Sun, H., Lam, Y., Chen, L., Wang, Q., et al. (2014) · Blood · doi:10.1182/blood-2014-01-549162 · Cited by 113 · see citing works

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

Knowles, H. J., Cleton-Jansen, A., Korsching, E., & Athanasou, N. A. (2010) · The FASEB Journal · doi:10.1096/fj.10-162230 · Cited by 113 · see citing works

Molecular Regulation of Tumor Angiogenesis and Perfusion via Redox Signaling

Miller, T. W., Isenberg, J. S., & Roberts, D. D. (2009) · Chemical Reviews · doi:10.1021/cr8005125 · Cited by 111 · see citing works

Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma

Ma, T., Jham, B. C., Hu, J., Friedman, E. R., Basile, J. R., Molinolo, A. A., Sodhi, A., & Montaner, S. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001065107 · Cited by 111 · see citing works

Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample

Robciuc, M. R., Tahvanainen, E., Jauhiainen, M., & Ehnholm, C. (2009) · Journal of Lipid Research · doi:10.1194/jlr.m002618 · Cited by 107 · see citing works

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue

Roberts, L. D., Murray, A. J., Menassa, D. A., Ashmore, T., Nicholls, A. W., & Griffin, J. L. (2011) · Genome biology · doi:10.1186/gb-2011-12-8-r75 · Cited by 106 · see citing works

Angiopoietin‐like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma

Chen, H., Kuo, T., Tseng, C., Ma, J., Yang, S., Yen, C., Yang, C., Sung, S., & Su, J. (2016) · Hepatology · doi:10.1002/hep.28773 · Cited by 104 · see citing works

Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema

Sodhi, A., Ma, T., Menon, D., Deshpande, M. M., Jee, K. J., Dinabandhu, A., Vancel, J., Lu, D., & Montaner, S. (2019) · Journal of Clinical Investigation · doi:10.1172/jci120879 · Cited by 104 · see citing works

Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility

Kuo, T.-C., Tan, C., Chang, Y.-W., Hong, C., Lee, W.-J., Chen, M.-W., Jeng, Y., Chiou, J., Yu, P., Chen, P., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci64044 · Cited by 104 · see citing works

Single-Cell Transcriptomics of Proliferative Phase Endometrium: Systems Analysis of Cell–Cell Communication Network Using CellChat

Fang, Z., Tian, Y., Sui, C., Guo, Y., Hu, X., Lai, Y., Liao, Z., Li, J., Feng, G., Jin, L., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.919731 · Cited by 102 · see citing works

Interaction of the coiled‐coil domain with glycosaminoglycans protects angiopoietin‐like 4 from proteolysis and regulates its antiangiogenic activity

Chomel, C., Cazes, A., Faye, C., Bignon, M., Perdiguero, E. G., Ardidie‐Robouant, C., Barret, A., Ricard‐Blum, S., Muller, L., Germain, S., et al. (2008) · The FASEB Journal · doi:10.1096/fj.08-115170 · Cited by 100 · see citing works

Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche

Zheng, J., Huynh, H., Umikawa, M., Silvany, R. E., & Zhang, C. C. (2010) · Blood · doi:10.1182/blood-2010-06-291716 · Cited by 95 · see citing works

Angiogenic Effects and Crosstalk of Adipose-Derived Mesenchymal Stem/Stromal Cells and Their Extracellular Vesicles with Endothelial Cells

Rautiainen, S., Laaksonen, T., & Koivuniemi, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910890 · Cited by 94 · see citing works

ANGPTL4 is a secreted tumor suppressor that inhibits angiogenesis

Okochi‐Takada, E., Hattori, N., Tsukamoto, T., Miyamoto, K., Ando, T., Ito, S., Yamamura, Y., Wakabayashi, M., Nobeyama, Y., & Ushijima, T. (2013) · Oncogene · doi:10.1038/onc.2013.174 · Cited by 91 · see citing works

Synoviocyte-Derived Angiopoietin-Like Protein 2 Contributes to Synovial Chronic Inflammation in Rheumatoid Arthritis

Okada, T., Tsukano, H., Endo, M., Tabata, M., Miyata, K., Kadomatsu, T., Miyashita, K., Semba, K., Nakamura, E., Tsukano, M., et al. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090865 · Cited by 90 · see citing works

Triglyceride-rich lipoproteins and remnants: targets for therapy?

Dallinga-Thie, G. M., Kroon, J., Borén, J., & Chapman, M. J. (2016) · Current Cardiology Reports · doi:10.1007/s11886-016-0745-6 · Cited by 90 · see citing works

Sex-Related Differences in Gene Expression by Porcine Aortic Valvular Interstitial Cells

McCoy, C. M., Nicholas, D. Q., & Masters, K. S. B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039980 · Cited by 86 · see citing works

Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes

Gong, X., Hou, Z., Endsley, M. P., Gronseth, E. I., Rarick, K. R., Jorns, J. M., Yang, Q., Du, Z., Yan, K., Bordas, M. L., et al. (2019) · npj Precision Oncology · doi:10.1038/s41698-019-0094-1 · Cited by 84 · see citing works

Local delivery of USC-derived exosomes harboring ANGPTL3 enhances spinal cord functional recovery after injury by promoting angiogenesis

Cao, Y. B., Xu, Y., Chen, C., Xie, H., Lü, H., & Hu, J. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-02078-8 · Cited by 84 · see citing works

Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue

Kroupa, O., Vorrsjö, E., Stienstra, R., Mattijssen, F., Nilsson, S. K., Sukonina, V., Kersten, S., Olivecrona, G., & Olivecrona, T. (2012) · BMC Physiology · doi:10.1186/1472-6793-12-13 · Cited by 82 · see citing works

Tie2 is tied at the cell-cell contacts and to extracellular matrix by Angiopoietin-1

Fukuhara, S., Sako, K., Noda, K., Nagao, K., Miura, K., & Mochizuki, N. (2009) · Experimental & Molecular Medicine · doi:10.3858/emm.2009.41.3.016 · Cited by 80 · see citing works

Transcriptome analysis of ageing in uninjured human Achilles tendon

Peffers, M. J., Fang, Y., Cheung, K., Wei, T. K. J., Clegg, P., & Birch, H. L. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0544-2 · Cited by 79 · see citing works

Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma

Comes, N., Buie, L. K., & Borrás, T. (2010) · Genes to Cells · doi:10.1111/j.1365-2443.2010.01483.x · Cited by 78 · see citing works

Single nucleotide polymorphisms associated with sporadic brain arteriovenous malformations: where do we stand?

Sturiale, C. L., Puca, A., Paola Sebastiani, B., Gatto, I., Albanese, A., Rocco, C. D., Maira, G., & Pola, R. (2012) · Brain · doi:10.1093/brain/aws180 · Cited by 77 · see citing works

Comparative analysis of the secretory proteome of human adipose stromal vascular fraction cells during adipogenesis

Kim, J. J., Choi, Y. S., Lim, S., Yea, K., Yoon, J. H., Jun, D., Ha, S. H., Kim, J., Kim, J. H., Suh, P., et al. (2009) · PROTEOMICS · doi:10.1002/pmic.200900218 · Cited by 75 · see citing works

ANGPTL2/LILRB2 signaling promotes the propagation of lung cancer cells

Liu, X., Yu, X., Xie, J., Zhan, M., Yu, Z., Xie, L., Zeng, H., Zhang, F., Chen, G., Yi, X., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.4217 · Cited by 74 · see citing works

Angiopoietin-like proteins 3, 4 and 8: regulating lipid metabolism and providing new hope for metabolic syndrome

Li, Y., & Teng, C. (2014) · Journal of drug targeting · doi:10.3109/1061186x.2014.928715 · Cited by 75 · see citing works

Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer

Parri, M., Pietrovito, L., Grandi, A., Campagnoli, S., Camilli, E. D., Bianchini, F., Marchiò, S., Bussolino, F., Jin, B., Sarmientos, P., et al. (2014) · Angiogenesis · doi:10.1007/s10456-014-9435-4 · Cited by 72 · see citing works

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover

Kirsch, N., Chang, L.-S., Koch, S., Glinka, A., Dolde, C. E., Colozza, G., Benitez, M. D. J., Robertis, E. M. D., & Niehrs, C. (2017) · Developmental Cell · doi:10.1016/j.devcel.2017.09.011 · Cited by 69 · see citing works

The Opening Act

Jin, S., & Patterson, C. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.161539 · Cited by 74 · see citing works

Angiopoietin-Like Proteins Potential Therapeutic Targets for Metabolic Syndrome and Cardiovascular Disease

Oike, Y., & Tabata, M. (2009) · Circulation Journal · doi:10.1253/circj.cj-09-0710 · Cited by 70 · see citing works

ANGPTL4 mediates the protective role of PPARγ activators in the pathogenesis of preeclampsia

Liu, L., Zhuang, X., Jiang, M., Guan, F., Fu, Q., & Lin, J. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.419 · Cited by 68 · see citing works

Cancer as a Proinflammatory Environment: Metastasis and Cachexia

Neto, N. I. P., Carnier, J., Oyama, L. M., Otoch, J. P., de Alcântara, P. S. M., Tokeshi, F., & do Nascimento, C. M. O. (2015) · Mediators of Inflammation · doi:10.1155/2015/791060 · Cited by 65 · see citing works

Angiopoietin‐Like 2 Promotes Atherogenesis in Mice

Farhat, N., Thorin‐Trescases, N., Mamarbachi, M., Villeneuve, L. R., Yu, C., Martel, C., Duquette, N., Gayda, M., Nigam, A., Juneau, M., et al. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.113.000201 · Cited by 65 · see citing works

AMP-activated protein kinase suppresses the expression of LXR/SREBP-1 signaling-induced ANGPTL8 in HepG2 cells

Lee, J., Hong, S., Park, S. E., Rhee, E., Park, C., Oh, K.-W., Park, S., & Lee, W. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.07.031 · Cited by 64 · see citing works

Differentiating vitreous proteomes in proliferative diabetic retinopathy using high-performance liquid chromatography coupled to tandem mass spectrometry

Wang, H., Feng, L., Hu, J., Xie, C., & Wang, F. (2012) · Experimental Eye Research · doi:10.1016/j.exer.2012.11.023 · Cited by 63 · see citing works

Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance

Yilmaz, Y. N., Ulukaya, E., Atuğ, Ö., & Dolar, E. (2009) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e32832b77ae · Cited by 63 · see citing works

Fibrinogen-Related Proteins in Tissue Repair: How a Unique Domain with a Common Structure Controls Diverse Aspects of Wound Healing

Zuliani‐Alvarez, L., & Midwood, K. S. (2014) · Advances in Wound Care · doi:10.1089/wound.2014.0599 · Cited by 63 · see citing works

Dual role of ANGPTL4 in inflammation

Zuo, Y., He, Z., Chen, Y., & Dai, L. (2023) · Inflammation Research · doi:10.1007/s00011-023-01753-9 · Cited by 64 · see citing works

Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes

Essalmani, R., Susan‐Resiga, D., Chamberland, A., Asselin, M.-C., Canuel, M., Constam, D. B., Creemers, J. W. M., Day, R. W., Gauthier, D., Prat, A., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.501304 · Cited by 62 · see citing works

Triglyceride lipases and atherosclerosis

Olivecrona, G., & Olivecrona, T. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32833ded83 · Cited by 62 · see citing works

Deep depletion of abundant serum proteins reveals low‐abundant proteins as potential biomarkers for human ovarian cancer

Lin, B., White, J. T., Wu, J., Lele, S., Old, L. J., Hood, L., & Odunsi, K. O. (2009) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200800141 · Cited by 61 · see citing works

Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes

Qaddoumi, M. G., Alanbaei, M., Hammad, M. M., Khairi, I. A., Cherian, P., Channanath, A. M., Thanaraj, T. A., Al‐Mulla, F., Abu‐Farha, M., & Abubaker, J. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-63149-7 · Cited by 59 · see citing works

Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events

Miida, T., & Hirayama, S. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328333269e · Cited by 59 · see citing works

Gene expression profiling of subcutaneous adipose tissue in morbid obesity using a focused microarray: Distinct expression of cell-cycle- and differentiation-related genes

Rodríguez‐Acebes, S., Palacios, N., Botella-Carretero, J. I., Olea, N., Crespo, L., Peromingo, R., Gómez‐Coronado, D., Lasunción, M. A., Vázquez, C., & Martı́nez-Botas, J. (2010) · BMC Medical Genomics · doi:10.1186/1755-8794-3-61 · Cited by 57 · see citing works

Cd11b+ myeloid cells support hepatic metastasis through down‐regulation of angiopoietin‐like 7 in cancer cells

Lim, S. Y., Gordon-Weeks, A. N., Allen, P. D., Kersemans, V., Beech, J. S., Smart, S., & Muschel, R. J. (2015) · Hepatology · doi:10.1002/hep.27838 · Cited by 57 · see citing works

Effects of Angiopoietin-Like 3 on Triglyceride Regulation, Glucose Homeostasis, and Diabetes

Christopoulou, E. C., Elisaf, M., & Filippatos, T. D. (2019) · Disease Markers · doi:10.1155/2019/6578327 · Cited by 56 · see citing works

Angiopoietin-like-2: a multifaceted protein with physiological and pathophysiological properties

Thorin‐Trescases, N., & Thorin, É. (2014) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2014.19 · Cited by 56 · see citing works

Clinicopathological significance of angiopoietin-like protein 4 expression in oesophageal squamous cell carcinoma

Shibata, K., Nakayama, T., Hirakawa, H., Hidaka, S., & Nagayasu, T. (2010) · Journal of Clinical Pathology · doi:10.1136/jcp.2010.078600 · Cited by 56 · see citing works

ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation

Cho, D. I., Ahn, M. J., Cho, H. H., Cho, M., Jun, J. H., Kang, B. G., Lim, S. Y., Yoo, S. J., Kim, M. R., Kim, H.-S., et al. (2023) · Experimental & Molecular Medicine · doi:10.1038/s12276-023-00937-x · Cited by 55 · see citing works

Serum levels of angiopoietin-related growth factor are increased in metabolic syndrome

Namkung, J., Koh, S. B., Kong, I. D., Choi, J.-W., & Yeh, B.-I. (2010) · Metabolism · doi:10.1016/j.metabol.2010.05.013 · Cited by 54 · see citing works

Paired immunoglobulin-like receptor B regulates platelet activation

Fan, X., Shi, P., Dai, J., Lu, Y., Chen, X., Liu, X., Zhang, K., Wu, X., Sun, Y., Wang, K., et al. (2014) · Blood · doi:10.1182/blood-2014-03-557645 · Cited by 53 · see citing works

Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm

Bourcier, R., Scouarnec, S. L., Bonnaud, S., Karakachoff, M., Bourcereau, E., Heurtebise-Chrétien, S., Baron‐Menguy, C., Christian Dina, C., Simonet, F., Moles, A., et al. (2018) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.12.006 · Cited by 52 · see citing works

Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism

Kim, T. H., Hong, D.-G., & Yang, Y. M. (2021) · Biomedicines · doi:10.3390/biomedicines9121903 · Cited by 52 · see citing works

Cyclic Strain Alters the Expression and Release of Angiogenic Factors by Human Tendon Cells

Mousavizadeh, R., Khosravi, S., Behzad, H., McCormack, R. G., Duronio, V., & Scott, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0097356 · Cited by 48 · see citing works

Angiopoietin-Like 4 (ANGPTL4) Gene Polymorphisms and Risk of Brain Arteriovenous Malformations

Mikhak, B., Weinsheimer, S., Pawlikowska, L., Poon, A., Kwok, P., Lawton, M. T., Chen, Y., Zaroff, J. G., Sidney, S. S., McCulloch, C. E., et al. (2011) · Cerebrovascular Diseases · doi:10.1159/000322601 · Cited by 46 · see citing works

Microarray gene expression profiles of fasting induced changes in liver and adipose tissues of pigs expressing the melanocortin-4 receptor D298N variant

Lkhagvadorj, S., Qu, L., Cai, W., Couture, O. P., Barb, C. R., Hausman, G. J., Nettleton, D. S., Anderson, L. L., Dekkers, J. C. M., & Tuggle, C. K. (2009) · Physiological Genomics · doi:10.1152/physiolgenomics.90372.2008 · Cited by 45 · see citing works

Angiopoietin-like protein 4 significantly predicts future cardiovascular events in coronary patients

Muendlein, A., Saely, C. H., Leiherer, A., Fraunberger, P., Kinz, E., Rein, P., Vonbank, A., Zanolin, D., Malin, C., & Drexel, H. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.10.028 · Cited by 45 · see citing works

Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia

Tarugi, P., Bertolini, S., & Calandra, S. (2018) · Journal of Biomedical Research · doi:10.7555/jbr.32.20170114 · Cited by 44 · see citing works

Secretomics for skeletal muscle cells: A discovery of novel regulators?

Yoon, J. H., Kim, J., Song, P., Lee, T. G., Suh, P., & Ryu, S. H. (2012) · Advances in Biological Regulation · doi:10.1016/j.jbior.2012.03.001 · Cited by 44 · see citing works

Angiopoietin-Like 2, a Circadian Gene, Improves Type 2 Diabetes Through Potentiation of Insulin Sensitivity in Mice Adipocytes

Kitazawa, M., Nagano, M., Masumoto, K., Shigeyoshi, Y., Natsume, T., & Hashimoto, S. (2011) · Endocrinology · doi:10.1210/en.2010-1407 · Cited by 43 · see citing works

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells

Xiao, Y., Jiang, Z., Li, Y., Ye, W., Jia, B., Zhang, M., Xu, Y., Wu, D., Lai, L., Chen, Y., et al. (2015) · Haematologica · doi:10.3324/haematol.2014.118612 · Cited by 43 · see citing works

Decreased Concentrations of the Lipoprotein Lipase Inhibitor Angiopoietin-Like Protein 4 and Increased Serum Triacylglycerol Are Associated With Increased Neonatal Fat Mass in Pregnant Women With Gestational Diabetes Mellitus

Ortega, H., Schaefer-Graf, U. M., Meitzner, K., Abou‐Dakn, M., & Herrera, E. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1614 · Cited by 42 · see citing works

The effect of calving in the summer on the hepatic transcriptome of Holstein cows during the peripartal period

Shahzad, K., Akbar, H., Vailati-Riboni, M., Basiricò, L., Morera, P., Rodriguez‐Zas, S. L., Nardone, A., Bernabucci, U., & Loor, J. J. (2015) · Journal of Dairy Science · doi:10.3168/jds.2015-9409 · Cited by 41 · see citing works

Identification of a new secretory factor, CCDC3/Favine, in adipocytes and endothelial cells

Kobayashi, S., Fukuhara, A., Taguchi, T., Matsuda, M., Tochino, Y., Otsuki, M., & Shimomura, I. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.12.142 · Cited by 41 · see citing works

High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation

Thorin‐Trescases, N., & Thorin, É. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/1096385 · Cited by 41 · see citing works

Tissue expression of angiopoietin-like protein 4 in cattle1

Mamedova, L. K., Robbins, K., Johnson, B. J., & Bradford, B. J. (2009) · Journal of Animal Science · doi:10.2527/jas.2009-2258 · Cited by 41 · see citing works

Angiopoietin-like 4: A novel molecular hallmark in oral Kaposi’s sarcoma

Hu, J., Jham, B. C., Ma, T., Friedman, E. R., Ferreira, L., Wright, J. M., Accurso, B. T., Allen, C. M., Basile, J. R., & Montaner, S. (2011) · Oral Oncology · doi:10.1016/j.oraloncology.2011.02.018 · Cited by 40 · see citing works

Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin

Kuo, T., Chen, T.-C., Yan, S. L., Foo, F., Ching, C., McQueen, A., & Wang, J.-C. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m047860 · Cited by 38 · see citing works

New Therapeutic Targets for Intraocular Pressure Lowering

Rocha‐Sousa, A., Rodrigues‐Araújo, J., Gouveia, P., Barbosa‐Breda, J., Azevedo-Pinto, S., Pereira-Silva, P., & Leite-Moreira, A. F. (2013) · ISRN Ophthalmology · doi:10.1155/2013/261386 · Cited by 40 · see citing works

Angiopoietin-Like 7 Is an Anti-Angiogenic Protein Required to Prevent Vascularization of the Cornea

Toyono, T., Usui, T., Yokoo, S., Taketani, Y., Nakagawa, S., Kuroda, M., Yamagami, S., & Amano, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116838 · Cited by 39 · see citing works

HOX Genes Family and Cancer: A Novel Role for Homeobox B9 in the Resistance to Anti-Angiogenic Therapies

Contarelli, S., Fedele, V., & Melisi, D. (2020) · Cancers · doi:10.3390/cancers12113299 · Cited by 38 · see citing works

Serum level of ANGPTL4 as a potential biomarker in renal cell carcinoma

Dong, D., Jia, L., Zhou, Y., Ren, L., Li, J., & Zhang, J. (2017) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2016.12.017 · Cited by 37 · see citing works

Pleiotropic effects of angiopoietin-like proteins (Angptls) on angiogenesis and metabolism

尾池, 雄. (2007) · 医学のあゆみ

Angiopoietin-Like Proteins: A Comprehensive Look

Santulli, G. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00004 · Cited by 320 · see citing works

Recent advance in the investigation of angiopoietin-like protein

Jing-min, Z. (2007) · Yixue yanjiusheng xuebao

Angiopoietin-Related/Angiopoietin-Like Proteins Regulate Angiogenesis

Oike, Y., Yasunaga, K., & Suda, T. (2004) · International Journal of Hematology · doi:10.1532/ijh97.04034 · Cited by 160 · see citing works

Angiopoietins and Angiopoietin-Like Proteins in Angiogenesis

Morisada, T., Kubota, Y., Urano, T., Suda, T., & Oike, Y. (2006) · Endothelium · doi:10.1080/10623320600697989 · Cited by 90 · see citing works