Metabolic syndrome update

Inflammation and Atherosclerosis

Libby, P., Ridker, P. M., & Maseri, A. (2002) · Circulation · doi:10.1161/hc0902.104353 · Cited by 7,724 · see citing works

Standards of medical care in diabetes—2014

American Diabetes Association (2014) · Diabetes Care · doi:10.2337/dc14-s014 · Cited by 4,572 · see citing works

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

Cannon, C. P., Blazing, M. A., Giugliano, R. P., McCagg, A., White, J. A., Theroux, P., Darius, H., Lewis, B. S., Ophuis, T. O., Jukema, J. W., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1410489 · Cited by 4,487 · see citing works

Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Inzucchi, S. E., Bergenstal, R. M., Buse, J. B., Diamant, M., Ferrannini, E., Nauck, M., Peters, A. L., Tsapas, A., Wender, R., & Matthews, D. R. (2012) · Diabetologia · doi:10.1007/s00125-012-2534-0 · Cited by 3,919 · see citing works

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

Diabetes Prevention Program Research Group (2009) · The Lancet · doi:10.1016/s0140-6736(09)61457-4 · Cited by 3,020 · see citing works

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

The AIM-HIGH Investigators (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1107579 · Cited by 2,911 · see citing works

Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

(2010) · New England Journal of Medicine · doi:10.1056/nejmoa1001282 · Cited by 2,837 · cited 2× · see citing works

Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis

Buchwald, H., Estok, R., Fahrbach, K., Banel, D., Jensen, M. D., Pories, W. J., Bantle, J. P., & Sledge, I. (2009) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.09.041 · Cited by 2,551 · see citing works

Inflammatory links between obesity and metabolic disease

Lumeng, C. N., & Saltiel, A. R. (2011) · Journal of Clinical Investigation · doi:10.1172/jci57132 · Cited by 2,319 · see citing works

Effects of extended-release niacin with laropiprant in high-risk patients

The HPS2-THRIVE Collaborative Group (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1300955 · Cited by 1,668 · see citing works

Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events

Sabatine, M. S., Giugliano, R. P., Wiviott, S. D., Raal, F. J., Blom, D. J., Robinson, J., Ballantyne, C. M., Somaratne, R., Legg, J., Wasserman, S. M., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1500858 · Cited by 1,509 · see citing works

Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Goldstein, L. B., Bushnell, C. D., Adams, R. J., Appel, L. J., Braun, L. T., Chaturvedi, S., Creager, M. A., Culebras, A., Eckel, R. H., Hart, R. G., et al. (2011) · Stroke · doi:10.1161/str.0b013e3181fcb238 · Cited by 1,306 · see citing works

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

Ridker, P. M., Thuren, T., Zalewski, A., & Libby, P. (2011) · American Heart Journal · doi:10.1016/j.ahj.2011.06.012 · Cited by 799 · see citing works

Pre-Diabetes, Metabolic Syndrome, and Cardiovascular Risk

Grundy, S. M. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.080 · Cited by 627 · see citing works

Effects of Fenofibrate Treatment on Cardiovascular Disease Risk in 9,795 Individuals With Type 2 Diabetes and Various Components of the Metabolic Syndrome

Scott, R., O'Brien, R., Fulcher, G., Pardy, C., d'Emden, M., Tse, D., Taskinen, M.-R., Ehnholm, C., Keech, A., & on behalf of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study Investigators (2009) · Diabetes Care · doi:10.2337/dc08-1543 · Cited by 551 · see citing works

Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome

Grundy, S. M. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00033-2 · Cited by 525 · cited 2× · see citing works

Lipids, apolipoproteins, and their ratios in relation to cardiovascular events with statin treatment

Kastelein, J. J. P., van der Steeg, W. A., Holme, I., Gaffney, M., Cater, N. B., Barter, P., Deedwania, P., Olsson, A. G., Boekholdt, S. M., Demicco, D. A., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.713438 · Cited by 478 · see citing works

Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study

Deedwania, P., Barter, P., Carmena, R., Fruchart, J.-C., Grundy, S. M., Haffner, S., Kastelein, J. J., LaRosa, J. C., Schachner, H., Shepherd, J., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69292-1 · Cited by 387 · see citing works

High density lipoproteins and coronary heart disease

Barter, P. J., & Rye, K.-A. (1996) · Atherosclerosis · doi:10.1016/0021-9150(95)05675-0 · Cited by 377 · see citing works

Influence of body fat content and distribution on variation in metabolic risk

Vega, G. L., Adams-Huet, B., Peshock, R., Willett, D., Shah, B., & Grundy, S. M. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0814 · Cited by 312 · see citing works

Non-high-density lipoprotein and very-low-density lipoprotein cholesterol and their risk predictive values in coronary heart disease

Liu, J., Sempos, C. T., Donahue, R. P., Dorn, J., Trevisan, M., & Grundy, S. M. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.06.032 · Cited by 277 · see citing works

Adipose tissue and metabolic syndrome: too much, too little or neither

Grundy, S. M. (2015) · European Journal of Clinical Investigation · doi:10.1111/eci.12519 · Cited by 187 · see citing works

Non–High-Density Lipoprotein Cholesterol Versus Apolipoprotein B in Cardiovascular Risk Stratification

Ramjee, V., Sperling, L. S., & Jacobson, T. A. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.05.009 · Cited by 157 · see citing works

The Effects of Carbohydrate, Unsaturated Fat, and Protein Intake on Measures of Insulin Sensitivity

Gadgil, M. D., Appel, L. J., Yeung, E., Anderson, C. A. M., Sacks, F. M., & Miller, E. R. (2013) · Diabetes Care · doi:10.2337/dc12-0869 · Cited by 120 · see citing works

Obesity and cardiovascular disease: a scientific statement from the American Heart Association

Powell-Wiley, T. M., Poirier, P., Burke, L. E., Després, J.-P., Gordon-Larsen, P., Lavie, C. J., Lear, S. A., Ndumele, C. E., Neeland, I. J., Sanders, P., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000973 · Cited by 3,691 · see citing works

Cardiovascular-kidney-metabolic health: a presidential advisory from the American Heart Association

Ndumele, C. E., Rangaswami, J., Chow, S. L., Neeland, I. J., Tuttle, K. R., Khan, S. S., Coresh, J., Mathew, R. O., Baker-Smith, C. M., Carnethon, M. R., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001184 · Cited by 2,208 · see citing works

Dietary lipids, gut microbiota and lipid metabolism

Schoeler, M., & Caesar, R. (2019) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-019-09512-0 · Cited by 1,163 · see citing works

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

Li, Z., Yi, C.-X., Katiraei, S., Kooijman, S., Zhou, E., Chung, C. K., Gao, Y., van den Heuvel, J. K., Meijer, O. C., Berbée, J. F. P., et al. (2018) · Gut · doi:10.1136/gutjnl-2017-314050 · Cited by 674 · see citing works

Sarcopenic obesity, insulin resistance, and their implications in cardiovascular and metabolic consequences

Hong, S.-H., & Choi, K. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21020494 · Cited by 390 · see citing works

Adiponectin signaling and function in insulin target tissues

Ruan, H., & Dong, L. Q. (2016) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjw014 · Cited by 395 · see citing works

Metabolic syndrome in polycystic ovary syndrome: a systematic review, meta‐analysis and meta‐regression

Lim, S. S., Kakoly, N. S., Tan, J. W. J., Fitzgerald, G., Bahri Khomami, M., Joham, A. E., Cooray, S. D., Misso, M. L., Norman, R. J., Harrison, C. L., et al. (2019) · Obesity Reviews · doi:10.1111/obr.12762 · Cited by 316 · see citing works

Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss

Hyde, P. N., Sapper, T. N., Crabtree, C. D., LaFountain, R. A., Bowling, M. L., Buga, A., Fell, B., McSwiney, F. T., Dickerson, R. M., Miller, V. J., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.128308 · Cited by 210 · see citing works

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance

Price, N. L., Singh, A. K., Rotllan, N., Goedeke, L., Wing, A., Canfrán-Duque, A., Diaz-Ruiz, A., Araldi, E., Baldán, Á., Camporez, J.-P., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.01.074 · Cited by 110 · see citing works

Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants

Shabalala, S. C., Johnson, R., Basson, A. K., Ziqubu, K., Hlengwa, N., Mthembu, S. X. H., Mabhida, S. E., Mazibuko-Mbeje, S. E., Hanser, S., Cirilli, I., et al. (2022) · Antioxidants · doi:10.3390/antiox11102071 · Cited by 102 · see citing works

2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome

Ndumele, C. E., Rodriguez, F., Dixon, D. L., Khan, S. S., Mukherjee, D., Bajaj, M., Bangalore, S., Bozkurt, B., Breathett, K., Clarke, S. L., et al. (2026) · JACC · doi:10.1016/j.jacc.2026.03.056 · Cited by 90 · see citing works

Waist-to-height ratio and BMI as predictive markers for insulin resistance in women with PCOS in Kolkata, India

Bhattacharya, K., Sengupta, P., Dutta, S., Chaudhuri, P., Das Mukhopadhyay, L., & Syamal, A. K. (2021) · Endocrine · doi:10.1007/s12020-020-02555-3 · Cited by 45 · see citing works

20-Hydroxyecdysone ameliorates metabolic and cardiovascular dysfunction in high-fat-high-fructose-fed ovariectomized rats

Buniam, J., Chukijrungroat, N., Rattanavichit, Y., Surapongchai, J., Weerachayaphorn, J., Bupha-Intr, T., & Saengsirisuwan, V. (2020) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-020-02936-1 · Cited by 35 · see citing works

Epidemiology of Obesity and Pharmacologic Treatment Options

Shettar, V., Patel, S., & Kidambi, S. (2017) · Nutrition in Clinical Practice · doi:10.1177/0884533617713189 · Cited by 26 · see citing works

The Political Economy of Food

Harris, J., Anderson, M., Clément, C., & Nisbett, N. (2019) · IDS Bulletin · doi:10.19088/1968-2019.112 · Cited by 21 · see citing works

Transgenerational effects of obesogenic diets in rodents: A meta‐analysis

Anwer, H., Morris, M. J., Noble, D. W. A., Nakagawa, S., & Lagisz, M. (2022) · Obesity Reviews · doi:10.1111/obr.13342 · Cited by 14 · see citing works

Dietary Supplementation with 20-Hydroxyecdysone Ameliorates Hepatic Steatosis and Reduces White Adipose Tissue Mass in Ovariectomized Rats Fed a High-Fat, High-Fructose Diet

Buniam, J., Chansela, P., Weerachayaphorn, J., & Saengsirisuwan, V. (2023) · Biomedicines · doi:10.3390/biomedicines11072071 · Cited by 9 · see citing works

Maternal and dietary factors are associated with metabolic syndrome in women with a previous history of gestational diabetes mellitus

Hasbullah, F. Y., Mohd Yusof, B.-N., Abdul Ghani, R., Mat Daud, Z. ‘., Appannah, G., Abas, F., & Shyam, S. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192416797 · Cited by 4 · see citing works