Childhood obesity and the timing of puberty

Ahmed, M. Lynn; Ong, Ken K.; Dunger, David B.

doi:10.1016/j.tem.2009.02.004

Cited by 409Hypothalamic control of reproductive hormonesObesity, Physical Activity, DietOvarian function and disorders

Childhood obesity and the timing of puberty

Ahmed, M. Lynn, Ong, Ken K., Dunger, David B.·2009·Trends in Endocrinology & Metabolism

DOI 10.1016/j.tem.2009.02.004

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Abstract

The potential relationship between childhood obesity and earlier puberty onset has major public health implications. Earlier menarche in girls is associated with increased risk of adult obesity, type 2 diabetes and breast cancer. Current methods for assessing puberty are unreliable, with a lack of consensus regarding the impact of childhood obesity on breast development and/or age of menarche. Effects of obesity on early puberty in boys are more contentious, necessitating development of robust biomarkers. The possibility of the obesity epidemic lowering the age of puberty onset fuels concerns over the growing mismatch in age of sexual and social maturity. Here, we describe the biological basis linking childhood obesity to early puberty and consider evidence for a trend towards its earlier onset.

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Numerous factors may accelerate puberty in humans and animals including a stressful early environment or absence of a father in the household, early exposure to endocrine disruptors, or childhood obesity.
“numerous factors may accelerate puberty in humans and animals including a stressful early environment or absence of a father in the household (Belsky, 2012), early exposure to endocrine disruptors (Meeker, 2012), or childhood obesity (Ahmed et al., 2009)”
From Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017) · cites this paper as Ahmed et al., 2009

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Authors: Ahmed, M. L., Ong, K. K., & Dunger, D. B.
Affiliations: University of Cambridge (GB)
Corresponding author: Dunger, David B.
ORCID: Ong, Ken K.
Dunger, David B.
Venue: Trends in Endocrinology & Metabolism
Publisher: Elsevier BV
Published: 2009-07
Volume: 20
Issue: 5
Pages: 237-242
ISSN: 1043-2760 (ISSN-L)
DOI: 10.1016/j.tem.2009.02.004
OpenAlex: W2010987536
Cited by: 409
References: 75
Citations by year: 2026: 13 · 2025: 22 · 2024: 21 · 2023: 17 · 2022: 45 · 2021: 28 · 2020: 35 · 2019: 18 · 2018: 28 · 2017: 23 · 2016: 20 · 2015: 25 · 2014: 26 · 2013: 30 · 2012: 31
FWCI: 2.72
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Endocrinology and Metabolism (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute for Health and Care Research (NF-SI-0508-10274)
Topics: Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Keywords: childhood obesity, puberty onset, early menarche, breast development, adolescent boys, obesity epidemic, type 2 diabetes risk, breast cancer risk, adult obesity risk
MeSH terms: Body Weight, Child, Female, Humans, Male, Obesity, Puberty, Puberty, Precocious

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Childhood obesity and the timing of puberty

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