Stacked Bt Proteins Pose No New Risks to Nontarget Arthropods
Abstract
Concerns have been raised that multiple insecticidal proteins produced by genetically engineered (GE) crops may interact unexpectedly and pose new threats to biodiversity and nontarget organisms. We reviewed the literature to assess whether this concern is justified and whether the current regulatory framework needs to be adapted to address this concern.
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Numerous laboratory studies have demonstrated that Cry1- and Cry2-class Bt proteins are specific to Lepidoptera and Cry3-class proteins to Chrysomelidae.
“numerous non-target laboratory studies with a wide range of taxa using purified Bt proteins, plant material, or prey that had consumed Bt proteins have demonstrated the specificity of Cry1- and Cry2-class proteins to Lepidoptera and Cry3-class proteins to Chrysomelidae (Coleoptera) [47, 61–63].”
From Does the growing of Bt maize change abundance or ecological function of non-target animals compared to the growing of non-GM maize? A systematic review (2022) · cites this paper as [63]
Cites
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Meissle, M., Naranjo, S. E., & Romeis, J. (2022) · Environmental Evidence · doi:10.1186/s13750-022-00272-0 · Cited by 41 · see citing works
“…numerous non-target laboratory studies with a wide range of taxa using purified Bt proteins, plant material, or prey that had consumed Bt proteins have demonstrated the specificity of Cry1-and Cry2-class proteins to Lepidoptera and Cry3-class proteins to Chrysomelidae (Coleoptera) [47, 61–63].”
Self-citation
- Authors
- Romeis, J., & Meissle, M.
- Affiliations
- Agroscope (CH)
- Corresponding author
- Romeis, Jörg
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 38
- Issue
- 3
- Pages
- 234-236
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2999004537
- Semantic Scholar
- fc9057913099337d496a79b412445b49f6df7d7a
- Cited by
- 19
- References
- 14
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 3 · 2022: 7 · 2021: 3 · 2020: 2
- FWCI
- 2.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Insect Resistance and Genetics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
- Keywords
- genetically modified crops, non-target arthropods, biodiversity risk, regulatory framework
- MeSH terms
- Bacillus thuringiensis Toxins, Animals, Arthropods, Endotoxins, Hemolysin Proteins, Crops, Agricultural, Plants, Genetically Modified, Ecotoxicology
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