The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
On-Site Therapeutic Drug Monitoring
Open accessAbstract
Recent technological advances have stimulated efforts to bring personalized medicine into practice. Yet, traditional application fields like therapeutic drug monitoring (TDM) have remained rather under-appreciated. Owing to clear dose-response relationships, TDM could improve patient outcomes and reduce healthcare costs. While chromatography-based routine practices are restricted due to high costs and turnaround times, biosensors overcome these limitations by offering on-site analysis. Nevertheless, sensor-based approaches have yet to break through for clinical TDM applications, due to the gap between scientific and clinical communities. We provide a critical overview of current TDM practices, followed by a TDM guideline to establish a common ground across disciplines. Finally, we discuss how the translation of sensor systems for TDM can be facilitated, by highlighting the challenges and opportunities.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis
Gao, W., Emaminejad, S., Nyein, H. Y. Y., Challa, S., Chen, K., Peck, A., Fahad, H. M., Ota, H., Shiraki, H., Kiriya, D., et al. (2016) · Nature · doi:10.1038/nature16521 · Cited by 5,087
Guns, Germs, and Steel: The Fates of Human Societies.
Hardin, G., & Diamond, J. (1997) · Population and Development Review · doi:10.2307/2137390 · Cited by 4,979
Wearable biosensors for healthcare monitoring
Kim, J., Campbell, A. S., de Ávila, B. E.-F., & Wang, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0045-y · Cited by 3,373
A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat
Koh, A., Kang, D., Xue, Y., Lee, S., Pielak, R. M., Kim, J., Hwang, T., Min, S., Banks, A., Bastien, P., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf2593 · Cited by 1,308
Lee, H., Song, C., Hong, Y. S., Kim, M., Cho, H. R., Kang, T., Shin, K., Choi, S. H., Hyeon, T., & Kim, D.-H. (2017) · Science Advances · doi:10.1126/sciadv.1601314 · Cited by 1,118
Disposable Sensors in Diagnostics, Food, and Environmental Monitoring
Dincer, C., Bruch, R., Costa‐Rama, E., Fernández‐Abedul, M. T., Merkoçi, A., Manz, A., Urban, G. A., & Güder, F. (2019) · Advanced Materials · doi:10.1002/adma.201806739 · Cited by 955
Self-citationWearable Sensors for Biochemical Sweat Analysis
Bandodkar, A. J., Jeang, W. J., Ghaffari, R., & Rogers, J. A. (2019) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-061318-114910 · Cited by 387
Therapeutic drug monitoring of β-lactams in critically ill patients: proof of concept
Roberts, J. A., Ulldemolins, M., Roberts, M. S., McWhinney, B., Ungerer, J., Paterson, D. L., & Lipman, J. (2010) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2010.06.008 · Cited by 334
Self-citationMethylxanthine Drug Monitoring with Wearable Sweat Sensors
Tai, L., Gao, W., Chao, M., Bariya, M., Ngo, Q. P., Shahpar, Z., Nyein, H. Y. Y., Park, H., Sun, J., Jung, Y., et al. (2018) · Advanced Materials · doi:10.1002/adma.201707442 · Cited by 310
Cited by
End-to-end design of wearable sensors
Ates, H. C., Nguyen, P. Q., Gonzalez-Macia, L., Morales-Narváez, E., Güder, F., Collins, J. J., & Dincer, C. (2022) · Nature Reviews Materials · doi:10.1038/s41578-022-00460-x · Cited by 1,306
Self-citationWearable Electrochemical Sensors for the Monitoring and Screening of Drugs
Teymourian, H., Parrilla, M., Sempionatto, J. R., Montiel, N. F., Barfidokht, A., Van Echelpoel, R., De Wael, K., & Wang, J. (2020) · ACS Sensors · doi:10.1021/acssensors.0c01318 · Cited by 423
A wireless patch for the monitoring of C-reactive protein in sweat
Tu, J., Min, J., Song, Y., Xu, C., Li, J., Moore, J., Hanson, J., Hu, E., Parimon, T., Wang, T.-Y., et al. (2023) · Nature Biomedical Engineering · doi:10.1038/s41551-023-01059-5 · Cited by 395
Hurkacz, M., Dobrek, L., & Wiela-Hojeńska, A. (2021) · Molecules · doi:10.3390/molecules26247456 · Cited by 60
Metadata
- Authors
- Ates, H. C., Roberts, J. A., Lipman, J., Cass, A. E. G., Urban, G. A., & Dincer, C.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 38
- Issue
- 11
- Pages
- 1262-1277
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W3015167435
- Cited by
- 268
- References
- 60
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: On-Site Therapeutic Drug Monitoring. https://app.cochat.ai/papers/10.1016/j.tibtech.2020.03.001
- The paper
- Ates, H. C., Roberts, J. A., Lipman, J., Cass, A. E. G., Urban, G. A., & Dincer, C. (2020). On-Site Therapeutic Drug Monitoring. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2020.03.001
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
