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Improving the bioavailability of phenolic compounds by loading them within lipid-based nanocarriers

Faridi Esfanjani, Afshin, Assadpour, Elham, Jafari, Seid Mahdi·2018·Trends in Food Science & Technology

Abstract

Abstract Background Phenolic compounds1 are one of the main interested nutraceuticals in the food and pharmaceutical industries. The application of phenolics is limited due to their low bioavailability, low solubility, low stability, and un-targeted release. These limitations could be overcome by novel ‘‘lipid-based nano-encapsulation technologies’’ capable of appropriated and targeted delivery functions into foods. Scope and approach In this review, preparation, application, and characterization of lipid-based nanocarriers for phenolics have been considered and discussed including nano-emulsions, nano-scale phospholipids, and nanostructured lipid carriers. The bioavailability of nano-encapsulated phenolic products and capability of them to produce functional foods have been considered as well. Key findings and conclusions In the food and nutraceutical industries, the main aims of loading phenolics into nanocarriers are masking their undesirable flavor for oral administration, providing high stability and high absorption, and better release in gastrointestinal (GIT) conditions. Compared with micro-sized carriers, nanocapsules based on lipid formulations provide more surface area and have the potential to enhance solubility, improve bioavailability, and ameliorate controlled release of the nano-encapsulated phenolic compounds.

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Metadata

Authors
Faridi Esfanjani, A., Assadpour, E., & Jafari, S. M.
Venue
Trends in Food Science & Technology
Publisher
Elsevier BV
Published
2018-06
Volume
76
Pages
56-66
ISSN
0924-2244 (ISSN-L)
OpenAlex
W2796917181
Cited by
405
References
3
FWCI
45.71
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Improving the bioavailability of phenolic compounds by loading them within lipid-based nanocarriers. https://app.cochat.ai/papers/10.1016/j.tifs.2018.04.002
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Faridi Esfanjani, A., Assadpour, E., & Jafari, S. M. (2018). Improving the bioavailability of phenolic compounds by loading them within lipid-based nanocarriers. Trends in Food Science & Technology. https://doi.org/10.1016/j.tifs.2018.04.002

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