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Cited by 359

The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.

Which is the best food emerging solvent: IL, DES or NADES?

Benvenutti, Laís, Zielinski, Acácio Antonio Ferreira, Ferreira, Sandra Regina Salvador·2019·Trends in Food Science & Technology

Abstract

Abstract Background Bioactive compounds have been intensely studied because of their biological properties that provide health benefits. However, for chemical or biological applications, these compounds are obtained mostly by using organic solvents. Emergent technologies consider the combination of methods and process optimization to improve the utilization of raw material, decreasing process costs, time and energy consumption. Additionally, due to the arising interest for green processes, alternative solvents have been developed. Ionic liquids (IL), deep eutectic solvents (DES) and, recently, natural deep eutectic solvents (NADES) can show high ability to extract organic, inorganic and polymeric bio-compounds. Overall, these promising solvents are environmentally friendly and less toxic than conventional extraction solvents. Scope and approach This review summarizes the use of IL, DES, and NADES for the extraction of bioactive compounds from natural products, presenting their evolution, process variables, target compounds, extraction techniques employed and future perspectives. Key findings and conclusions The use of these emerging solvents for extraction process has shown to be promising. Besides its high solvation ability and versatility, these solvents may present low or none toxicity. Particularly, it is allowed the use of NADES in food and pharmaceutical formulations, however, some DES and IL are in need of further investigation. IL, DES, and NADES are recyclables and can be related to sustainable processes. Therefore, to expand the applications of these emerging solvents for the recovery of bioactive compounds, the extraction mechanisms involved need to be proper elucidated.

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Metadata

Authors
Benvenutti, L., Zielinski, A. A. F., & Ferreira, S. R. S.
Venue
Trends in Food Science & Technology
Publisher
Elsevier BV
Published
2019-08
Volume
90
Pages
133-146
ISSN
0924-2244 (ISSN-L)
OpenAlex
W2952419552
Cited by
359
References
90
FWCI
6.05
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Which is the best food emerging solvent: IL, DES or NADES? https://app.cochat.ai/papers/10.1016/j.tifs.2019.06.003
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Benvenutti, L., Zielinski, A. A. F., & Ferreira, S. R. S. (2019). Which is the best food emerging solvent: IL, DES or NADES? Trends in Food Science & Technology. https://doi.org/10.1016/j.tifs.2019.06.003

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