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Cited by 784Phytochemicals and Antioxidant ActivitiesAgricultural and Biological ResearchFood Science and Nutritional Studies

Major phytochemicals: Recent advances in health benefits and extraction method

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Kumar, Ashwani, P, Nirmal, Kumar, Mukul, Jose, Anina, Tomer, Vidisha, Oz, Emel, Proestos, Charalampos, Zeng, Maomao +3 more·2023·Molecules
DOI 10.3390/molecules28020887PMC PMC9862941
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Abstract

Recent scientific studies have established a relationship between the consumption of phytochemicals such as carotenoids, polyphenols, isoprenoids, phytosterols, saponins, dietary fibers, polysaccharides, etc., with health benefits such as prevention of diabetes, obesity, cancer, cardiovascular diseases, etc. This has led to the popularization of phytochemicals. Nowadays, foods containing phytochemicals as a constituent (functional foods) and the concentrated form of phytochemicals (nutraceuticals) are used as a preventive measure or cure for many diseases. The health benefits of these phytochemicals depend on their purity and structural stability. The yield, purity, and structural stability of extracted phytochemicals depend on the matrix in which the phytochemical is present, the method of extraction, the solvent used, the temperature, and the time of extraction.

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  • Flavonoids are part of the class of nutraceuticals that have been demonstrated to improve insulin sensitivity, manage hyperglycemia in diabetics, and govern metabolism.

    “Flavonoids are part of the class of nutraceuticals that have been demonstrated to improve insulin sensitivity, manage hyperglycemia in diabetics, and govern metabolism.”

    From A critical review on diabetes mellitus type 1 and type 2 management approaches: from lifestyle modification to current and novel targets and therapeutic agents. (2024) · cites this paper as [132]

    Section 3.2 (Polyphenols; page not provided) identifies flavonoids as phytochemicals and says they have been found beneficial in diabetes. It does not specify improved insulin sensitivity, management of hyperglycemia in people with diabetes, or regulation of metabolism. Section 3.6 attributes improved insulin sensitivity to dietary fiber, not flavonoids. (LLM, conf=0.88)

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Authors
Kumar, A., P, N., Kumar, M., Jose, A., Tomer, V., Oz, E., Proestos, C., Zeng, M., Elobeid, T., K, S., & Oz, F.
Affiliations
  • Rani Lakshmi Bai Central Agricultural University, Jhansi (IN)
  • Department of Food Technology and Nutrition, Lovely Professional University, Phagwara 144411, Punjab, India
  • Lovely Professional University (IN)
  • Vellore Institute of Technology University (IN)
  • Department of Food Engineering, Faculty of Agriculture, Ataturk University, Erzurum 25240, Turkey
  • National and Kapodistrian University of Athens (GR)
  • Jiangnan University (CN)
  • Qatar University (QA)
Corresponding author
Kumar, Ashwani
ORCID
Venue
Molecules
Publisher
MDPI AG
Published
2023-01-16
Volume
28
Issue
2
Pages
887
ISSN
1420-3049 (ISSN-L)
DOI
10.3390/molecules28020887
PMC
PMC9862941
OpenAlex
W4316664297
Cited by
784
References
6
Citations by year
2026: 251 · 2025: 322 · 2024: 178 · 2023: 31 · 2018: 1
FWCI
15.58
Type
journal article
Language
en
Open access
Licence
Locations
  • Molecules (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Qatar University QSpace (Qatar University) (submittedVersion)
Funders
  • RESEARCH–CREATE-INNOVATE (T1EDK-3816, TAD-2022-11816)
  • the Open Access Fund (T1EDK-3816, TAD-2022-11816)
Topics
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
  • Health Sciences › Nursing › Nutrition and Dietetics › Food Science and Nutritional Studies
Keywords
phytochemicals, carotenoids, polyphenols, terpenoids, phytosterols, saponins, dietary fiber, polysaccharides, functional foods, nutraceuticals, health benefits, disease prevention, phytochemical extraction, extraction methods, structural stability, food matrix
MeSH terms
Antioxidants, Phytosterols, Dietary Supplements, Polyphenols, Phytochemicals

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