The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding
Open accessAbstract
Klebsiella pneumoniae carbapenemases (KPCs) were first identified in 1996 in the USA. Since then, regional outbreaks of KPC-producing K. pneumoniae have occurred in the USA, and have spread internationally. Dissemination of blaKPC involves both horizontal transfer of blaKPC genes and plasmids, and clonal spread. Of epidemiological significance, the international spread of KPC-producing K. pneumoniae is primarily associated with a single multilocus sequence type (ST), ST258, and its related variants. However, the molecular factors contributing to the success of ST258 largely remain unclear. Here, we review the recent progresses in understanding KPC-producing K. pneumoniae that is contributing to our knowledge of plasmid and genome composition and structure among the KPC epidemic clone, and identify possible factors that influence its epidemiological success.
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Self-citationMultilocus Sequence Typing of Klebsiella pneumoniae Nosocomial Isolates
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Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance
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Klebsiella pneumoniae carbapenemase variants: the new threat to global public health
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Metadata
- Authors
- Chen, L., Mathema, B., Chavda, K. D., DeLeo, F. R., Bonomo, R. A., & Kreiswirth, B. N.
- Venue
- Trends in Microbiology
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 22
- Issue
- 12
- Pages
- 686-696
- ISSN
- 0966-842X (ISSN-L)
- OpenAlex
- W2078043965
- Cited by
- 554
- References
- 73
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- green
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- Chen, L., Mathema, B., Chavda, K. D., DeLeo, F. R., Bonomo, R. A., & Kreiswirth, B. N. (2014). Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding. Trends in Microbiology. https://doi.org/10.1016/j.tim.2014.09.003
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