RNA-based therapeutics to treat human fungal infections

Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

Tuerk, C., & Gold, L. (1990) · Science · doi:10.1126/science.2200121 · Cited by 10,421 · see citing works

Hidden Killers: Human Fungal Infections

Brown, G. D., Denning, D. W., Gow, N. A. R., Levitz, S. M., Netea, M. G., & White, T. C. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004404 · Cited by 4,284 · see citing works

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

Chalmers, Z. R., Connelly, C. F., Fabrizio, D., Gay, L., Ali, S. M., Ennis, R., Schrock, A., Campbell, B., Shlien, A., Chmielecki, J., et al. (2017) · Genome Medicine · doi:10.1186/s13073-017-0424-2 · Cited by 3,519 · see citing works

The druggable genome

Hopkins, A. L., & Groom, C. R. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd892 · Cited by 3,305 · see citing works

Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA

Karikó, K., Buckstein, M., Ni, H., & Weissman, D. (2005) · Immunity · doi:10.1016/j.immuni.2005.06.008 · Cited by 2,728 · see citing works

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., & Tuschl, T. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.07.007 · Cited by 1,718 · see citing works

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

Corbett, K. S., Edwards, D. K., Leist, S. R., Abiona, O. M., Boyoglu-Barnum, S., Gillespie, R. A., Himansu, S., Schäfer, A., Ziwawo, C. T., DiPiazza, A. T., et al. (2020) · Nature · doi:10.1038/s41586-020-2622-0 · Cited by 1,615 · see citing works

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

Fisher, M. C., Hawkins, N. J., Sanglard, D., & Gurr, S. J. (2018) · Science · doi:10.1126/science.aap7999 · Cited by 1,555 · see citing works

Aspergillus fumigatus and Aspergillosis in 2019

Latgé, J.-P., & Chamilos, G. (2019) · Clinical Microbiology Reviews · doi:10.1128/cmr.00140-18 · Cited by 1,400 · see citing works

Overcoming cellular barriers for RNA therapeutics

Dowdy, S. F. (2017) · Nature Biotechnology · doi:10.1038/nbt.3802 · Cited by 1,139 · see citing works

Small dsRNAs induce transcriptional activation in human cells

Li, L., Okino, S. T., Zhao, H., Pookot, D., Place, R. F., Urakami, S., Enokida, H., & Dahiya, R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607015103 · Cited by 770 · see citing works

Current prospects for RNA interference-based therapies

Davidson, B. L., & McCray, P. B. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2968 · Cited by 760 · see citing works

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

Anderson, B. R., Muramatsu, H., Nallagatla, S. R., Bevilacqua, P. C., Sansing, L. H., Weissman, D., & Karikó, K. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq347 · Cited by 682 · see citing works

Advances in the delivery of RNA therapeutics: from concept to clinical reality

Kaczmarek, J. C., Kowalski, P. S., & Anderson, D. G. (2017) · Genome Medicine · doi:10.1186/s13073-017-0450-0 · Cited by 656 · see citing works

AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals

Fagard, M., Boutet‐Mercey, S., Morel, J., Bellini, C., & Vaucheret, H. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.200217597 · Cited by 565 · see citing works

Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture

Fisher, M. C., Gurr, S. J., Cuomo, C. A., Blehert, D. S., Jin, H., Stukenbrock, E. H., Stajich, J., Kahmann, R., Boone, C. M., Denning, D. W., et al. (2020) · mBio · doi:10.1128/mbio.00449-20 · Cited by 558 · see citing works

Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development

Dhuri, K., Bechtold, C., Quijano, E., Pham, H. T. T., Gupta, A., Vikram, A., & Bahal, R. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9062004 · Cited by 554 · see citing works

Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species

Muñoz, J. F., Gade, L., Chow, N. A., Loparev, V. N., Juieng, P., Berkow, E. L., Farrer, R. A., Litvintseva, A. P., & Cuomo, C. A. (2018) · Nature Communications · doi:10.1038/s41467-018-07779-6 · Cited by 458 · see citing works

CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia

Xu, L., Wang, J., Liu, Y., Xie, L., Su, B., Mou, D., Wang, L., Liu, T., Wang, X., Zhang, B., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1817426 · Cited by 454 · see citing works

Untitled work

(2014) · doi:10.1128/cmr.00126-13 · Cited by 437 · see citing works

The challenge and prospect of mRNA therapeutics landscape

Weng, Y., Li, C., Yang, T., Hu, B., Zhang, M., Guo, S., Xiao, H., Liang, X.-J., & Huang, Y. (2020) · Biotechnology Advances · doi:10.1016/j.biotechadv.2020.107534 · Cited by 417 · see citing works

Candida auris: an Emerging Fungal Pathogen

Spivak, E. S., & Hanson, K. E. (2018) · Journal of Clinical Microbiology · doi:10.1128/jcm.01588-17 · Cited by 393 · see citing works

Aptamers in the Therapeutics and Diagnostics Pipelines

Kaur, H., Bruno, J. G., Kumar, A., & Sharma, T. K. (2018) · Theranostics · doi:10.7150/thno.25958 · Cited by 368 · see citing works

Impact of mRNA chemistry and manufacturing process on innate immune activation

Nelson, J., Sorensen, E. W., Mintri, S., Rabideau, A. E., Zheng, W., Besin, G., Khatwani, N., Su, S. V., Miracco, E. J., Issa, W. J., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz6893 · Cited by 354 · see citing works

RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?

Bobbin, M. L., & Rossi, J. J. (2016) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010715-103633 · Cited by 352 · see citing works

Diverse Pathways Generate MicroRNA-like RNAs and Dicer-Independent Small Interfering RNAs in Fungi

Lee, H.-C., Li, L., Gu, W., Xue, Z., Crosthwaite, S. K., Pertsemlidis, A., Lewis, Z., Freitag, M., Selker, E. U., Mello, C. C., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.04.005 · Cited by 345 · see citing works

Extracellular vesicles versus synthetic nanoparticles for drug delivery

Witwer, K. W., & Wolfram, J. (2021) · Nature Reviews Materials · doi:10.1038/s41578-020-00277-6 · Cited by 338 · see citing works

Spray‐induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake

Qiao, L., Lan, C., Capriotti, L., Ah‐Fong, A. M. V., Sánchez, J. N., Hamby, R., Heller, J., Zhao, H., Glass, N. L., Judelson, H. S., et al. (2021) · Plant Biotechnology Journal · doi:10.1111/pbi.13589 · Cited by 324 · see citing works

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection

Ye, L., Wang, J., Beyer, A. I., Teque, F., Cradick, T. J., Qi, Z., Chang, J. C., Bao, G., Muench, M. O., Yu, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1407473111 · Cited by 320 · see citing works

Extracellular transmission of a DNA mycovirus and its use as a natural fungicide

Yu, X., Li, B., Fù, Y., Xiè, J., Chéng, J., Ghabrial, S. A., Li, G., Yi, X., & Jiāng, D. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213755110 · Cited by 315 · see citing works

CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients

Su, S., Hu, B., Shao, J., Shen, B., Du, J., Du, Y., Zhou, J., Yu, L., Zhang, L., Chen, F., et al. (2016) · Scientific Reports · doi:10.1038/srep20070 · Cited by 310 · see citing works

Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin

Karikó, K., Muramatsu, H., Keller, J. M., & Weissman, D. (2012) · Molecular Therapy · doi:10.1038/mt.2012.7 · Cited by 282 · see citing works

RNA therapeutics on the rise

Wang, F., Zuroske, T., & Watts, J. K. (2020) · Nature Reviews Drug Discovery · doi:10.1038/d41573-020-00078-0 · Cited by 275 · see citing works

Compatibility with Killer Explains the Rise of RNAi-Deficient Fungi

Drinnenberg, I. A., Fink, G. R., & Bartel, D. P. (2011) · Science · doi:10.1126/science.1209575 · Cited by 233 · see citing works

Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies Are a Risk Factor for Central Nervous System Infection by Cryptococcus gattii in Otherwise Immunocompetent Patients

Saijo, T., Chen, J., Chen, S. C.-A., Rosen, L. B., Yi, J., Sorrell, T. C., Bennett, J. E., Holland, S. M., Browne, S., & Kwon-Chung, K. J. (2014) · mBio · doi:10.1128/mbio.00912-14 · Cited by 226 · see citing works

Aspiring Antifungals: Review of Current Antifungal Pipeline Developments

Gintjee, T., Donnelley, M., & Thompson, G. (2020) · Journal of Fungi · doi:10.3390/jof6010028 · Cited by 225 · see citing works

Cross-kingdom RNA trafficking and environmental RNAi — nature's blueprint for modern crop protection strategies

Cai, Q., He, B., Kogel, K., & Jin, H. (2018) · Current Opinion in Microbiology · doi:10.1016/j.mib.2018.02.003 · Cited by 223 · see citing works

Paving the Road for RNA Therapeutics

Dammes, N., & Peer, D. (2020) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2020.08.004 · Cited by 220 · see citing works

Small RNAs and extracellular vesicles: New mechanisms of cross-species communication and innovative tools for disease control

Cai, Q., He, B., Weiberg, A., Buck, A. H., & Jin, H. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1008090 · Cited by 183 · see citing works

MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Sarker, D., Plummer, R., Meyer, T., Sodergren, M. H., Basu, B., Chee, C. E., Huang, K., Palmer, D. H., Ma, Y. T., Evans, T. R. J., et al. (2020) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-0414 · Cited by 182 · see citing works

Antifungal drug resistance evoked via RNAi-dependent epimutations

Calo, S., Shertz-Wall, C., Lee, S. C., Bastidas, R. J., Nicolás, F. E., Granek, J. A., Mieczkowski, P., Torres-Martínez, S., Ruiz-Vázquez, R. M., Cardenas, M. E., et al. (2014) · Nature · doi:10.1038/nature13575 · Cited by 175 · see citing works

Fungal vaccines, mechanism of actions and immunology: A comprehensive review

Nami, S., Mohammadi, R., Vakili, M., Khezripour, K., Mirzaei, H., & Morovati, H. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.10.075 · Cited by 136 · see citing works

Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer

Voutila, J., Reebye, V., Roberts, T. C., Protopapa, P., Andrikakou, P., Blakey, D. C., Habib, R., Huber, H. E., Sætrom, P., Rossi, J. J., et al. (2017) · Molecular Therapy · doi:10.1016/j.ymthe.2017.07.018 · Cited by 128 · see citing works

Glimmers in illuminating the druggable genome

Rodgers, G., Austin, C., Anderson, J., Pawlyk, A., Colvis, C., Margolis, R., & Baker, J. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.252 · Cited by 126 · see citing works

Ex vivo cell-based CRISPR/Cas9 genome editing for therapeutic applications

Li, Y., Glass, Z., Huang, M., Chen, Z., & Xu, Q. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2019.119711 · Cited by 113 · see citing works

Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications

Zhang, X., Xu, Q., Zi, Z., Liu, Z., Wan, C., Crisman, L., Shen, J., & Liu, X. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.11.007 · Cited by 113 · see citing works

Divergent transcription is associated with promoters of transcriptional regulators

Lepoivre, C., Belhocine, M., Bergon, A., Griffon, A., Yammine, M., Vanhille, L., Cabeza, J. Z., Garibal, M., Koch, F., Maqbool, M. A., et al. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-914 · Cited by 111 · see citing works

Therapeutic Potential of Small Molecules and Engineered Proteins

Gurevich, E. V., & Gurevich, V. V. (2013) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-41199-1_1 · Cited by 94 · see citing works

β Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus

Ma, S., Viola, R., Sui, L., Cherubini, V., Barbetti, F., & Egli, D. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.11.006 · Cited by 83 · see citing works

RNA Vaccines: A Suitable Platform for Tackling Emerging Pandemics?

Sandbrink, J. B., & Shattock, R. J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.608460 · Cited by 79 · see citing works

Small molecules that target group II introns are potent antifungal agents

Fedorova, O., Jagdmann, G. E., Adams, R. L., Yuan, L., Zandt, M. C. V., & Pyle, A. M. (2018) · Nature Chemical Biology · doi:10.1038/s41589-018-0142-0 · Cited by 78 · see citing works

Developing Small Activating RNA As a Therapeutic: Current Challenges and Promises

Kwok, A., Raulf, N., & Habib, N. A. (2019) · Therapeutic Delivery · doi:10.4155/tde-2018-0061 · Cited by 78 · see citing works

Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus

Shopova, I. A., Belyaev, I., Dasari, P., Jahreis, S., Stroe, M. C., Cseresnyés, Z., Zimmermann, A.-K., Medyukhina, A., Svensson, C., Krüger, T., et al. (2020) · mBio · doi:10.1128/mbio.00596-20 · Cited by 74 · see citing works

Overview of treatment options for invasive fungal infections

Pound, M. W., Townsend, M. L., DiMondi, V. P., Wilson, D. T., & Drew, R. H. (2011) · Medical Mycology · doi:10.3109/13693786.2011.560197 · Cited by 69 · see citing works

Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers

Howard, J. J., Sturge, C. R., Moustafa, D. A., Daly, S. M., Marshall‐Batty, K. R., Felder-Scott, C. F., Zamora, D., Yabe-Gill, M., Labandeira‐Rey, M., Bailey, S. M., et al. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01938-16 · Cited by 66 · see citing works

Immune modulation by complement receptor 3-dependent human monocyte TGF-β1-transporting vesicles

Halder, L. D., Jo, E. A. H., Hasan, M. Z., Ferreira‐Gomes, M., Krüger, T., Westermann, M., Palme, D. I., Rambach, G., Beyersdorf, N., Speth, C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16241-5 · Cited by 61 · see citing works

The lncRNA RZE1 Controls Cryptococcal Morphological Transition

Chacko, N., Zhao, Y., Yang, E., Wang, L., Cai, J. J., & Lin, X. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005692 · Cited by 60 · see citing works

Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation

Bernstein, D. A., Vyas, V. K., Weinberg, D. E., Drinnenberg, I. A., Bartel, D. P., & Fink, G. R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1118859109 · Cited by 55 · see citing works

Extracellular RNAs: A Secret Arm of Immune System Regulation

de Candia, P., De Rosa, V., Casiraghi, M., & Matarese, G. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.r115.708842 · Cited by 50 · see citing works

Development of MTL-CEBPA: Small Activating RNA Drug for Hepatocellular Carcinoma

Setten, R. L., Lightfoot, H. L., Habib, N. A., & Rossi, J. J. (2018) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201019666180611093428 · Cited by 48 · see citing works

Gene Network Polymorphism Illuminates Loss and Retention of Novel RNAi Silencing Components in the Cryptococcus Pathogenic Species Complex

Feretzaki, M., Billmyre, R. B., Clancey, S. A., Wang, X., & Heitman, J. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1005868 · Cited by 45 · see citing works

RNA Silencing Gene Truncation in the Filamentous Fungus Aspergillus nidulans

Hammond, T. M., Bok, J. W., Andrewski, M. D., Reyes-Domínguez, Y., Scazzocchio, C., & Keller, N. P. (2007) · Eukaryotic Cell · doi:10.1128/ec.00355-07 · Cited by 42 · see citing works

Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo

Moustafa, D. A., Wu, A. W., Zamora, D., Daly, S. M., Sturge, C. R., Pybus, C. A., Geller, B. L., Goldberg, J. B., & Greenberg, D. E. (2021) · mBio · doi:10.1128/mbio.02411-20 · Cited by 40 · see citing works

Fungal Vaccines and ImmunotherapeuticsPreprint

Santos, E., & Levitz, S. M. (2014) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a019711 · Cited by 38 · see citing works

Cryptococcus neoformans - Infected Macrophages Release Proinflammatory Extracellular Vesicles: Insight into Their Components by Multi-omics

Zhang, L., Zhang, K., Li, H., Coelho, C., Gonçalves, D. D. S., Fu, M. S., Li, X., Nakayasu, E. S., Kim, Y., Liao, W., et al. (2021) · mBio · doi:10.1128/mbio.00279-21 · Cited by 38 · see citing works

Rapid Worldwide Emergence of Pathogenic Fungi

Rhodes, J. L. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.06.009 · Cited by 32 · see citing works

Development-dependent scavenging of nucleic acids in the filamentous fungusAspergillus fumigatus

Jöchl, C., Loh, E., Ploner, A., Haas, H., & Hüttenhofer, A. (2009) · RNA Biology · doi:10.4161/rna.6.2.7717 · Cited by 28 · see citing works

A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA

Cánovas-Márquez, J. T., Falk, S., Nicolás, F. E., Padmanabhan, S., Perez, R. Z., Sánchez‐Ferrer, Á., Navarro, E., & Garre, V. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab238 · Cited by 15 · see citing works

RNA Therapeutics Are Stepping Out of the Maze

Agrawal, S. (2020) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2020.08.007 · Cited by 14 · see citing works

Molecular mechanisms governing antifungal drug resistance

Lee, Y., Robbins, N., & Cowen, L. E. (2023) · npj Antimicrobials and Resistance · doi:10.1038/s44259-023-00007-2 · Cited by 304 · see citing works

Progress and prospects of mRNA-based drugs in pre-clinical and clinical applications

Shi, Y., Shi, M., Wáng, Y., & You, J. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02002-z · Cited by 231 · see citing works

Confronting antifungal resistance, tolerance, and persistence: advances in drug target discovery and delivery systems

Chen, L., Zhang, L., Xie, Y., Wang, Y., Tian, X., Fang, W., Xue, X., & Wang, L. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115007 · Cited by 63 · see citing works

Humans vs. Fungi: An Overview of Fungal Pathogens against Humans

Thambugala, K. M., Daranagama, D. A., Tennakoon, D. S., Jayatunga, D. P. W., Hongsanan, S., & Xie, N. (2024) · Pathogens · doi:10.3390/pathogens13050426 · Cited by 52 · see citing works

Advances in the design and delivery of RNA vaccines for infectious diseases

Lokras, A. G., Bobak, T. R., Baghel, S. S., Sebastiani, F., & Foged, C. (2024) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2024.115419 · Cited by 50 · see citing works

Progress of polymer-based strategies in fungal disease management: Designed for different roles

Wu, S., Guo, W., Li, B., Zhou, H., Meng, H., Sun, J., Li, R., Guo, D., Zhang, X., Li, R., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1142029 · Cited by 28 · see citing works

Application of anti-fungal vaccines as a tool against emerging anti-fungal resistance

Kumar, R., & Srivastava, V. (2023) · Frontiers in Fungal Biology · doi:10.3389/ffunb.2023.1241539 · Cited by 28 · see citing works

Sulfur Metabolism as a Promising Source of New Antifungal Targets

Amich, J. (2022) · Journal of Fungi · doi:10.3390/jof8030295 · Cited by 20 · see citing works

Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model

Li, Y., Ambati, S., Meagher, R. B., & Lin, X. (2025) · npj Vaccines · doi:10.1038/s41541-025-01079-z · Cited by 18 · see citing works

Carbon Nanotube Hybrid Materials: Efficient and Pertinent Platforms for Antifungal Drug Delivery

Chandra, D. K., Reis, R. L., Kundu, S. C., Kumar, A., & Mahapatra, C. (2023) · Advanced Materials Technologies · doi:10.1002/admt.202301044 · Cited by 18 · see citing works

An Update on the Global Treatment of Invasive Fungal Infections

Munzen, M. E., Garcia, A. D. G., & Martinez, L. R. (2023) · Future Microbiology · doi:10.2217/fmb-2022-0269 · Cited by 15 · see citing works

Recent Advances and Future Perspectives in Mitigating Invasive Antifungal-Resistant Pathogen Aspergillus fumigatus in Africa

Achilonu, C. C., Davies, A. A., Kanu, O. O., Noel, C. B., & Oladele, R. O. (2023) · Current treatment options in infectious diseases/Current treatment options in infectious disease · doi:10.1007/s40506-023-00269-4 · Cited by 14 · see citing works

Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome

Kelani, A. A., Bruch, A., Rivieccio, F., Visser, C., Krüger, T., Weaver, D., Pan, X., Schäuble, S., Panagiotou, G., Kniemeyer, O., et al. (2023) · RNA · doi:10.1261/rna.079350.122 · Cited by 14 · see citing works

Plant-derived extracellular vesicles and nanoparticles: origins, functions, and applications

Alsaid, F., Davila, B., & He, B. (2026) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2026.1758558 · Cited by 12 · see citing works

Bioinformatics Approaches in the Development of Antifungal Therapeutics and Vaccines

Ahlawat, V., Sura, K., Singh, B., Dangi, M., & Chhillar, A. K. (2024) · Current Genomics · doi:10.2174/0113892029281602240422052210 · Cited by 7 · see citing works

Overcoming antifungal resistance in Candida albicans via RNA interference: a therapeutic perspective

Mundhe, A. K., & Rajkumari, R. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1675921 · Cited by 6 · see citing works

RNA-Based Vaccines and Therapeutics Against Intracellular Pathogens

Kola, N. S., Patel, D., & Thakur, A. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-3890-3_21 · Cited by 6 · see citing works

Enhanced antifungal activity of siRNA-loaded anionic liposomes against the human pathogenic fungus Aspergillus fumigatus

Yu, Y., Vogel, T., Hirsch, S., Gröll, J., Albrecht, K., & Beilhack, A. (2024) · Nanoscale · doi:10.1039/d4nr03225j · Cited by 5 · see citing works

RNA:DNA triplexes: a mechanism for epigenetic communication between hosts and microbes?

Bierhoff, H., Barber, A. E., & Blango, M. G. (2024) · mBio · doi:10.1128/mbio.01982-24 · Cited by 4 · see citing works

Hope on the Horizon? Aptamers in Diagnosis of Invasive Fungal Infections

Khodavaisy, S., & Xu, J. (2024) · Genes · doi:10.3390/genes15060733 · Cited by 4 · see citing works

Significance of immunotherapy for human fungal diseases and antifungal drug discovery

Mir, M. A., Jan, U., & Qadri, H. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-96127-1.00001-2 · Cited by 4 · see citing works

Research advances in capillary gel electrophoresis for detecting biomacromolecules

Liu, W.-J., Zhang, Y., Li, Q.-Y., Li, R.-T., Zhao, L., Gatera, T., Ma, Q., Yang, J.-L., & Shi, X.-F. (2026) · Journal of Chromatography A · doi:10.1016/j.chroma.2026.466850 · Cited by 3 · see citing works

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

Inukai, T., Watanabe, R., Murakami, Y., Cabral, H., Kuroda, M., & Nakamura, S. (2025) · Scientific Reports · doi:10.1038/s41598-025-02742-0 · Cited by 3 · see citing works

Two Novel Human Leukocyte Antigen Alleles Are Associated with Decreased Risk of Onychomycosis in a Large Cohort of Danish Blood Donors

Andersen, P. L., Jemec, G. B. E., Erikstrup, C., Didriksen, M., Dinh, K. M., Mikkelsen, S., Bruun, M. T., Hjalgrim, H., Hansen, T. F., Sækmose, S. G., et al. (2023) · Skin Appendage Disorders · doi:10.1159/000529092 · Cited by 3 · see citing works

Past, Present, and Future of RNA Modifications in Infectious Disease Research

Pan, X., Bruch, A., & Blango, M. G. (2024) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.4c00598 · Cited by 3 · see citing works

Yeast Model System Showed That Heterologously Expressed Mutant Atp9 Has a Negative Impact on Cell Growth by Causing ATP Depletion

Ito, T., Terai, K., Kosako, H., & Shinohara, Y. (2025) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b24-00787 · Cited by 2 · see citing works

Bridging Gaps in Fungal Keratitis Management: Novel Diagnostics, Drug Delivery Systems, and Gene Therapies

Shivgotra, R., Soni, B., Bakrey, H., Kaur, P., & Jain, S. K. (2026) · AAPS PharmSciTech · doi:10.1208/s12249-026-03368-9 · Cited by 2 · see citing works

Small non-coding RNAs in human fungal diseases: Host immune modulation and clinical relevance

Cunha-de-Oliveira, R., Vinagre, L. W. M. S., Duarte, J. R. G., da Silva, M. B., da Costa, P. F., Ribeiro‐dos‐Santos, Â., Santos, S., Salgado, C. G., & Pinto, P. (2026) · Fungal Biology Reviews · doi:10.1016/j.fbr.2026.100486 · Cited by 2 · see citing works

Computational Design and Experimental Evaluation of MERS-CoV siRNAs in Selected Cell Lines

Sohrab, S. S., El-Kafrawy, S. A., Mirza, Z., Hassan, A. M., Alsaqaf, F., & Azhar, E. I. (2023) · Diagnostics · doi:10.3390/diagnostics13010151 · Cited by 2 · see citing works

Crosslinking Biopolymers and Its Clinical Applications

Ahmed, S. A., Tumurkhuu, M., Valicherla, G. R., Malasala, S., Iqbal, B., Hasnain, S. M. M., & Warsi, M. H. (2026) · Materials horizons · doi:10.1007/978-981-95-2258-3_7 · Cited by 1 · see citing works

Delivery of siRNAs against MERS-CoV in Vero and HEK-293 cells: A comparative evaluation of transfection reagents

Sohrab, S. S., El-Kafrawy, S. A., Mirza, Z., Hassan, A. M., Alsaqaf, F., & Azhar, E. I. (2023) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2023.102540 · Cited by 1 · see citing works

Endophytic Fungi: Potential Source of Allelochemicals for Sustainable Agriculture

Zafar, S., Afzal, H., Ijaz, A., Ahmad, M., Zafar, M., Naz, T., & Datta, R. (2024) · Sustainable plant nutrition in a changing world · doi:10.1007/978-981-99-9388-8_30 · Cited by 1 · see citing works

RNAi: antifungal therapy against Invasive pulmonary aspergillosis (IPA) in humans

Kumar, M., Topno, R. K., & Kumar, R. (2023) · Indian Journal of Microbiology Research · doi:10.18231/j.ijmr.2023.022

RNA-Biologie von Pilzinfektionen

Blango, M. G. (2024) · BIOspektrum · doi:10.1007/s12268-024-2309-4

RNA as a Mediator of Host-Fungal Pathogenesis

Bruch, A., & Blango, M. G. (2024) · The mycota · doi:10.1007/978-3-031-64853-3_5

Prä-mRNA-Spleißen beeinflusst die Hyphenbildung bei Candida albicans

Kupczok, L., Sternisek, P., Bader, O., & Herzel, L. (2025) · BIOspektrum · doi:10.1007/s12268-025-2411-2

A Review of the Therapeutic Challenges and Novel Treatment Options in Mitigating Invasive Mycosis Associated with Aspergillus, Candida, Cryptococcus, and Pneumocystis

Meade, E., Slattery, M. A., & Garvey, M. (2026) · Journal of Fungi · doi:10.3390/jof12090659

COVID-19-Associated Fungal Co-Infections: Pathogenesis, Diagnostics, Biomarkers, and Therapeutic Strategies

Choudhury, S., Nawaar, N., Chowdhury, W. R., Roy, P., Khan, A. S., Ali, S., Zaki, R. M., Raihan, T., Mishra, M., Rabbee, M. F., et al. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15176896

Human neutrophils release extracellular RNA that modulates Aspergillus fumigatus gene expression across kingdomsPreprint

Bruch, A., Schrettenbrunner, L., Israni, B., Boehm, E., Pan, X., Visser, C., Orasch, T., Brakhage, A. A., & Blango, M. G. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.19.758605

RNA to the rescue

Rinaldi, A. C. (2020) · EMBO Reports · doi:10.15252/embr.202051013 · Cited by 9 · see citing works

Tailoring mRNA lipid nanoparticles for antifungal vaccines

Li, Y., Meagher, R. B., & Lin, X. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1013091 · Cited by 1 · see citing works

Clinical Trials on RNA-Based Therapeutics for the Treatment of Infectious Diseases and Other Pathologies

Ranga, V. (2025) · Springer eBooks · doi:10.1007/978-981-96-3456-9_9 · Cited by 1 · see citing works

Computational Tools: RNA Interference in Fungal Therapeutics

Jain, C. K., & Wadhwa, G. (2018) · Springer eBooks · doi:10.1007/978-981-10-7483-7_12 · Cited by 4 · see citing works

RNA as a Mediator of Host-Fungal Pathogenesis

Bruch, A., & Blango, M. G. (2024) · The mycota · doi:10.1007/978-3-031-64853-3_5