Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

Catterall, W. A., Chandy, K. G., Clapham, D. E., Gutman, G. A., Hofmann, F., Harmar, A. J., Abernethy, D. R., & Spedding, M. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.4.5 · Cited by 7,126 · see citing works

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., Dewhirst, M. W., Bigner, D. D., & Rich, J. N. (2006) · Nature · doi:10.1038/nature05236 · Cited by 6,363 · see citing works

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., & Cole, G. (1996) · Science · doi:10.1126/science.274.5284.99 · Cited by 4,210 · see citing works

Mammalian neural stem cells.

Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 3,949 · see citing works

Chemokines

Zlotnik, A., & Yoshie, O. (2000) · Immunity · doi:10.1016/s1074-7613(00)80165-x · Cited by 3,859 · see citing works

Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

Orimo, A., Gupta, P. B., Sgroi, D. C., Arenzana-Seisdedos, F., Delaunay, T., Naeem, R., Carey, V. J., Richardson, A. L., & Weinberg, R. A. (2005) · Cell · doi:10.1016/j.cell.2005.02.034 · Cited by 3,759 · see citing works

The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints

Fredriksson, R., Lagerström, M. C., Lundin, L.-G., & Schiöth, H. B. (2003) · Molecular Pharmacology · doi:10.1124/mol.63.6.1256 · Cited by 2,941 · see citing works

Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma

Galli, R., Binda, E., Orfanelli, U., Cipelletti, B., Gritti, A., Vitis, S. D., Fiocco, R., Foroni, C., DiMeco, F., & Vescovi, A. L. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1364 · Cited by 2,570 · see citing works

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

Zou, Y.-R., Kottmann, A. H., Kuroda, M., Taniuchi, I., & Littman, D. R. (1998) · Nature · doi:10.1038/31269 · Cited by 2,494 · see citing works

Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches

Sugiyama, T., Kohara, H., Noda, M., & Nagasawa, T. (2006) · Immunity · doi:10.1016/j.immuni.2006.10.016 · Cited by 2,419 · see citing works

Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain

Doetsch, F. K., García‐Verdugo, J. M., & Álvarez-Buylla, A. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-13-05046.1997 · Cited by 1,909 · see citing works

The stem-cell niche as an entity of action

Scadden, D. T. (2006) · Nature · doi:10.1038/nature04957 · Cited by 1,859 · see citing works

International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors

Murphy, P. M., Baggiolini, M., Charo, I. F., Hébert, C. A., Horuk, R., Matsushima, K., Miller, L. H., Oppenheim, J. J., & Power, C. A. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01439-x · Cited by 1,817 · see citing works

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

Liu, G., Yuan, X., Zeng, Z., Tunici, P., Ng, H., Abdulkadir, I. R., Lu, L., Irvin, D. K., Black, K. L., & Yu, J. S. (2006) · Molecular Cancer · doi:10.1186/1476-4598-5-67 · Cited by 1,790 · see citing works

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

Tachibana, K., Hirota, S., Iizasa, H., Yoshida, H., Kawabata, K., Kataoka, Y., Kitamura, Y., Matsushima, K., Yoshida, N., Nishikawa, S.-I., et al. (1998) · Nature · doi:10.1038/31261 · Cited by 1,527 · see citing works

The development of neural stem cells

Temple, S. (2001) · Nature · doi:10.1038/35102174 · Cited by 1,494 · see citing works

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

Bleul, C. C., Fuhlbrigge, R. C., Casasnovas, J. M., Aiuti, A., & Springer, T. A. (1996) · The Journal of experimental medicine · doi:10.1084/jem.184.3.1101 · Cited by 1,482 · see citing works

Stem Cell–like Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor

Bao, S., Wu, Q., Sathornsumetee, S., Hao, Y., Li, Z., Hjelmeland, A. B., Shi, Q., McLendon, R. E., Bigner, D. D., & Rich, J. N. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1010 · Cited by 1,347 · see citing works

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

Burns, J. M., Summers, B. C., Wang, Y., Melikian, A., Berahovich, R., Miao, Z., Penfold, M. E. T., Sunshine, M. J., Littman, D. R., Kuo, C. J., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20052144 · Cited by 1,264 · see citing works

The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis

Strieter, R. M., Polverini, P. J., Kunkel, S. L., Arenberg, D. A., Burdick, M. D., Kasper, J., Dzuiba, J., Van Damme, J., Walz, A., Marriott, D., et al. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.27348 · Cited by 1,222 · see citing works

C hemokines in I nnate and A daptive H ost D efense : Basic Chemokinese Grammar for Immune Cells

Rot, A., & von Andrian, U. H. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104543 · Cited by 1,209 · see citing works

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

Du, R., Lu, K. V., Petritsch, C. K., Liu, P., Ganß, R., Passegue, E. A., Song, H., VandenBerg, S. R., Johnson, R. S., Werb, Z., et al. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.01.034 · Cited by 1,131 · see citing works

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

Broxmeyer, H. E., Orschell, C. M., Clapp, D. W., Hangoc, G., Cooper, S. H., Plett, P. A., Liles, W. C., Li, X., Graham-Evans, B. E., Campbell, T., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041385 · Cited by 1,107 · see citing works

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway

Imitola, J., Raddassi, K., Park, K. I., Müeller, F.-J., Nieto, M., Teng, Y. D., Frenkel, D., Li, J., Sidman, R. L., Walsh, C. A., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408258102 · Cited by 1,056 · see citing works

A specialized vascular niche for adult neural stem cells

Tavazoie, M., Van der Veken, L., Silva-Vargas, V., Louissaint, M., Colonna, L., Zaidi, B., Garcia-Verdugo, J. M., & Doetsch, F. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.025 · Cited by 1,033 · see citing works

Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions

Shen, Q., Wang, Y., Kokovay, E., Lin, G., Chuang, S.-M., Goderie, S. K., Roysam, B., & Temple, S. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.026 · Cited by 1,027 · see citing works

Rat forebrain neurogenesis and striatal neuron replacement after focal stroke

Parent, J. M., Vexler, Z. S., Gong, C., Derugin, N., & Ferriero, D. M. (2002) · Annals of Neurology · doi:10.1002/ana.10393 · Cited by 1,020 · see citing works

Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain

Mirzadeh, Z., Merkle, F. T., Soriano-Navarro, M., Garcia-Verdugo, J. M., & Alvarez-Buylla, A. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.004 · Cited by 1,015 · see citing works

Human cortical glial tumors contain neural stem‐like cells expressing astroglial and neuronal markers in vitro

Ignatova, T. N., Kukekov, V. G., Laywell, E. D., Suslov, O. N., Vrionis, F. D., & Steindler, D. A. (2002) · Glia · doi:10.1002/glia.10094 · Cited by 992 · see citing works

How do stem cells find their way home?

Lapidot, T., Dar, A., & Kollet, Ó. (2005) · Blood · doi:10.1182/blood-2005-04-1417 · Cited by 985 · see citing works

Cellular Niches Controlling B Lymphocyte Behavior within Bone Marrow during Development

Tokoyoda, K., Egawa, T., Sugiyama, T., Choi, B.-I., & Nagasawa, T. (2004) · Immunity · doi:10.1016/j.immuni.2004.05.001 · Cited by 796 · see citing works

Persistent Production of Neurons from Adult Brain Stem Cells During Recovery after Stroke

Thored, P., Arvidsson, A., Cacci, E., Ahlenius, H., Kallur, T., Darsalia, V., Ekdahl, C. T., Kokaia, Z., & Lindvall, O. (2005) · Stem Cells · doi:10.1634/stemcells.2005-0281 · Cited by 714 · see citing works

Neural stem and progenitor cells in nestin‐GFP transgenic mice

Mignone, J., Kukekov, V. G., Chiang, A., Steindler, D. A., & Enikolopov, G. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.10964 · Cited by 705 · see citing works

Integrin Alpha 6 Regulates Glioblastoma Stem Cells

Lathia, J. D., Gallagher, J., Heddleston, J. M., Wang, J., Eyler, C. E., MacSwords, J., Wu, Q., Vasanji, A., McLendon, R. E., Hjelmeland, A. B., et al. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.02.018 · Cited by 655 · see citing works

The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

Möhle, R., Bautz, F., Rafii, S., Moore, M. A. S., Brugger, W., & Kanz, L. (1998) · Blood · doi:10.1182/blood.v91.12.4523 · Cited by 648 · see citing works

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

Sierro, F., Biben, C., Martínez‐Muñoz, L., Mellado, M., Ransohoff, R. M., Li, M., Woehl, B., Leung, H., Groom, J. R., Batten, M., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702229104 · Cited by 625 · see citing works

Control of Chemokine-Guided Cell Migration by Ligand Sequestration

Boldajipour, B. A., Mahabaleshwar, H., Kardash, E., Reichman‐Fried, M., Blaser, H., Minina, S., Wilson, D., Xu, Q., & Raz, E. (2008) · Cell · doi:10.1016/j.cell.2007.12.034 · Cited by 623 · see citing works

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

Rubin, J. B., Kung, A. L., Klein, R. S., Chan, J. A.-W., Sun, Y., Schmidt, K. F., Kieran, M. W., Luster, A. D., & Segal, R. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2235846100 · Cited by 615 · see citing works

Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination

Nait‐Oumesmar, B., Decker, L., Lachapelle, F., Avellana‐Adalid, V., Bachelin, C., & Van Evercooren, A. B. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00873.x · Cited by 560 · see citing works

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

Miao, Z., Luker, K. E., Summers, B. C., Berahovich, R., Bhojani, M. S., Rehemtulla, A., Kleer, C. G., Essner, J. J., Nasevicius, A., Luker, G. D., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610444104 · Cited by 528 · see citing works

CXCR7 Functions as a Scavenger for CXCL12 and CXCL11

Naumann, U., Cameroni, E., Pruenster, M., Mahabaleshwar, H., Raz, E., Zerwes, H., Rot, A., & Thelen, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009175 · Cited by 471 · see citing works

Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice

Picard-Riéra, N., Decker, L., Delarasse, C., Goude, K., Nait‐Oumesmar, B., Liblau, R., Pham-Dinh, D., & Evercooren, A. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.192314199 · Cited by 469 · see citing works

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1 alpha/CXC chemokine receptor 4 pathway

Teng, Y. D., Frenkel, D., Nieto, M., Müeller, F.-J., Park, K. I., Raddassi, K., Imitola, J., Li, J., Sidman, R. L., Walsh, C. A., et al. (2004) · Cited by 421 · see citing works

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

Lü, M., Grove, E. A., & Miller, R. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092013799 · Cited by 415 · see citing works

CXCR4 is required for the quiescence of primitive hematopoietic cells

Nie, Y., Han, Y.-C., & Zou, Y.-R. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20072513 · Cited by 407 · see citing works

Activated Neural Stem Cells Contribute to Stroke-Induced Neurogenesis and Neuroblast Migration toward the Infarct Boundary in Adult Rats

Zhang, R., Zhang, Z., Wang, L., Wang, Y., Goussev, A. V., Zhang, L., Ho, K., Morshead, C. M., & Chopp, M. (2004) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200404000-00009 · Cited by 382 · see citing works

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

Rodríguez, J. J., Jones, V. C., Tabuchi, M., Allan, S. M., Knight, E. M., LaFerla, F. M., Oddo, S., & Verkhratsky, A. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002935 · Cited by 377 · see citing works

Adult SVZ Lineage Cells Home to and Leave the Vascular Niche via Differential Responses to SDF1/CXCR4 Signaling

Kokovay, E., Goderie, S. K., Wang, Y., Lotz, S., Lin, G., Sun, Y., Roysam, B., Shen, Q., & Temple, S. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.05.019 · Cited by 358 · see citing works

Activation of the subventricular zone in multiple sclerosis: Evidence for early glial progenitors

Nait-Oumesmar, B., Picard-Riéra, N., Kerninon, C., Decker, L., Seilhean, D., Höglinger, G., Hirsch, E., Reynolds, R., & Evercooren, A. B.-V. (2007) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0606835104 · Cited by 336 · see citing works

Chemokines and leukocyte traffic

Sallusto, F., & Baggiolini, M. (2008) · Nature Immunology · doi:10.1038/ni.f.214 · Cited by 325 · see citing works

Molecular basis of cell migration in the fish lateral line: Role of the chemokine receptor CXCR4 and of its ligand, SDF1

David, N. B., Sapède, D., Saint-Etienne, L., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252339399 · Cited by 312 · see citing works

Intracerebral Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Amyloid-Beta Deposition and Rescues Memory Deficits in Alzheimer's Disease Mice by Modulation of Immune Responses

Lee, J. K., Jin, H. K., Endo, S., Schuchman, E. H., Carter, J., & Bae, J.-S. (2009) · Stem Cells · doi:10.1002/stem.277 · Cited by 303 · see citing works

Somatic control over the germline stem cell lineage during Drosophila spermatogenesis

Tran, J., Brenner, T. J., & DiNardo, S. (2000) · Nature · doi:10.1038/35037613 · Cited by 266 · see citing works

SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model

Wang, Y., Deng, Y., & Zhou, G. (2008) · Brain Research · doi:10.1016/j.brainres.2007.11.068 · Cited by 266 · see citing works

Chemotaxis of primitive hematopoietic cells in response to stromal cell–derived factor-1

Jo, D., Rafii, S., Hamada, T., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci7954 · Cited by 248 · see citing works

CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination

Patel, J. R., McCandless, E. E., Dorsey, D., & Klein, R. S. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006301107 · Cited by 231 · see citing works

Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain

Tran, P. B., Banisadr, G., Ren, D., Chenn, A., & Miller, R. J. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21229 · Cited by 229 · see citing works

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell‐mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

Ping, Y., Yao, X., Jian-yong, J., Zhao, L., Yu, S., Jiang, T., Lin, M. C., Chen, J., Wang, B., Zhang, R., et al. (2011) · The Journal of Pathology · doi:10.1002/path.2908 · Cited by 226 · see citing works

Current data and strategy in glioblastoma multiforme.

Iacob, G., & Dinca, E. B. (2009) · PubMed Central · Cited by 225 · see citing works

Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis

Carbajal, K. S., Schaumburg, C. S., Strieter, R. M., Kane, J. A. C., & Lane, T. E. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006375107 · Cited by 220 · see citing works

Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells

Tran, P. B., Ren, D., Veldhouse, T. J., & Miller, R. J. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20001 · Cited by 217 · see citing works

Tumorigenesis of Chemotherapeutic Drug-Resistant Cancer Stem-Like Cells in Brain Glioma

Kang, M., & Kang, S. (2007) · Stem Cells and Development · doi:10.1089/scd.2007.0006 · Cited by 215 · see citing works

Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells

Luker, K. E., Lewin, S. A., Mihalko, L. A., Schmidt, B. T., Winkler, J. S., Coggins, N. L., Thomas, D. G., & Luker, G. D. (2012) · Oncogene · doi:10.1038/onc.2011.633 · Cited by 198 · see citing works

AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates

Larochelle, A., Krouse, A. E., Metzger, M. E., et al. (2006) · Blood · doi:10.1182/blood-2005-09-3592 · Cited by 194 · see citing works

Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition

Parachikova, A., Nichol, K. E., & Cotman, C. W. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.12.008 · Cited by 193 · see citing works

Stroke‐induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF‐1 and GDNF

Dempsey, R. J., Sailor, K. A., Bowen, K. K., Türeyen, K., & Vemuganti, R. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02022.x · Cited by 176 · see citing works

Tumor Stromal-Derived Factor-1 Recruits Vascular Progenitors to Mitotic Neovasculature, where Microenvironment Influences Their Differentiated Phenotypes

Aghi, M. K., Cohen, K. S., Klein, R. J., Scadden, D. T., & Chiocca, E. A. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3759 · Cited by 175 · see citing works

Non-Cell-Autonomous Effects of Presenilin 1 Variants on Enrichment-Mediated Hippocampal Progenitor Cell Proliferation and Differentiation

Choi, S. H., Veeraraghavalu, K., Lazarov, O., Marler, S., Ransohoff, R. M., Ramirez, J., & Sisodia, S. S. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.033 · Cited by 171 · see citing works

A role for CXCL12 (SDF-1α) in the pathogenesis of multiple sclerosis: Regulation of CXCL12 expression in astrocytes by soluble myelin basic protein

Calderon, T. M., Eugenín, E. A., Lopez, L., Kumar, S. S., Hesselgesser, J., Raine, C. S., & Berman, J. W. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.05.003 · Cited by 166 · see citing works

Spatial and temporal expression of short, long/medium, or both opsins in human fetal cones

Xiao, M., & Hendrickson, A. E. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20001002)425:4 · Cited by 165 · see citing works

Maintaining Hematopoietic Stem Cells in the Vascular Niche

Kiel, M. J., & Morrison, S. J. (2006) · Immunity · doi:10.1016/j.immuni.2006.11.005 · Cited by 164 · see citing works

Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions

Ambrosini, E., Remoli, M. E., Giacomini, E., Rosicarelli, B., Serafini, B., Lande, R., Aloisi, F., & Coccia, E. M. (2005) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/01.jnen.0000173893.01929.fc · Cited by 161 · see citing works

CXCR4 mediates the proliferation of glioblastoma progenitor cells

Ehtesham, M., Mapara, K. Y., Stevenson, C. B., et al. (2008) · Cancer Letters · doi:10.1016/j.canlet.2008.09.034 · Cited by 151 · see citing works

The Chemokine Stromal Cell-Derived Factor-1 Regulates GABAergic Inputs to Neural Progenitors in the Postnatal Dentate Gyrus

Bhattacharyya, B. J., Banisadr, G., Jung, H., Ren, D., Cronshaw, D. G., Zou, Y.-R., & Miller, R. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1677-08.2008 · Cited by 149 · see citing works

The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury

Miller, J. T., Bartley, J., Wimborne, H., Walker, A. L., Hess, D. C., Hill, W., & Carroll, J. E. (2005) · BMC Neuroscience · doi:10.1186/1471-2202-6-63 · Cited by 145 · see citing works

Regional and cellular localization of the CXCl12/SDF‐1 chemokine receptor CXCR7 in the developing and adult rat brain

Schönemeier, B., Kolodziej, A., Schulz, S., Jacobs, S., Hoellt, V., & Stumm, R. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21780 · Cited by 141 · see citing works

Immune and nervous system CXCL12 and CXCR4: parallel roles in patterning and plasticity

Klein, R. S., & Rubin, J. B. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.04.002 · Cited by 132 · see citing works

Developmental pattern of expression of the alpha chemokine stromal cell‐derived factor 1 in the rat central nervous system

Tham, T. N., Lazarini, F., Franceschini, I., Lachapelle, F., Amara, A., & Dubois-Dalcq, M. E. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2000.01451.x · Cited by 131 · see citing works

Pulmonary Stromal-Derived Factor-1 Expression and Effect on Neutrophil Recruitment during Acute Lung Injury

Petty, J. M. A., Sueblinvong, V., Lenox, C. C., Jones, C. C., Cosgrove, G. P., Cool, C. D., Rai, P. R., Brown, K. K., Weiss, D. J., Poynter, M. E., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.12.8148 · Cited by 128 · see citing works

Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: In vivo evidence of a role for nerve growth factor

Calzà, L., Giardino, L., Pozza, M., Bettelli, C., Micera, A., & Aloe, L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.3209 · Cited by 123 · see citing works

Ischemia‐induced neurogenesis is preserved but reduced in the aged rodent brain

Jin, K., Minami, M., Xie, L., Sun, Y., Mao, X. O., Wang, Y., Simon, R. P., & Greenberg, D. A. (2004) · Aging Cell · doi:10.1111/j.1474-9728.2004.00131.x · Cited by 121 · see citing works

miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration

Staton, A. A., Knaut, H., & Giráldez, A. J. (2011) · Nature Genetics · doi:10.1038/ng.758 · Cited by 116 · see citing works

CXC Chemokine Receptor 4 Expression and Function in Human Astroglioma Cells

Oh, J., Drabik, K., Kutsch, O., Choi, C., Tousson, A., & Benveniste, E. N. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.4.2695 · Cited by 114 · see citing works

Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development

Tissir, F., Wang, C.-E., & Goffinet, A. M. (2004) · Developmental Brain Research · doi:10.1016/j.devbrainres.2004.01.002 · Cited by 114 · see citing works

Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain

Schönemeier, B., Schulz, S., Hoellt, V., & Stumm, R. K. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.04.010 · Cited by 106 · see citing works

Glioblastoma cancer stem cells: heterogeneity, microenvironment and related therapeutic strategies

Denysenko, T., Gennero, L., Roos, M. A., Melcarne, A., Junemann, C. V., Faccani, G., Morra, I., Cavallo, G. P., Reguzzi, S., Pescarmona, G., et al. (2010) · Cell Biochemistry and Function · doi:10.1002/cbf.1666 · Cited by 106 · see citing works

Hypoxia enhances CXCR4 expression in human microvascular endothelial cells and human melanoma cells.

Schutyser, E., Su, Y., Yu, Y., Gouwy, M., Zaja‐Milatovic, S., Damme, J. V., & Richmond, A. J. (2007) · PubMed · doi:10.1684/ecn.2007.0087 · Cited by 94 · see citing works

Nitric Oxide Donor Upregulation of Stromal Cell-Derived Factor-1/Chemokine (CXC Motif) Receptor 4 Enhances Bone Marrow Stromal Cell Migration into Ischemic Brain After Stroke

Cui, X., Chen, J., Zacharek, A., Li, Y., Roberts, C. J., Kapke, A., Savant‐Bhonsale, S., & Chopp, M. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0169 · Cited by 87 · see citing works

Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis

Ödemis, V., Lamp, E. C., Pezeshki, G., et al. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.07.019 · Cited by 84 · see citing works

Enriched environment promotes adult neural progenitor cell mobilization in mouse demyelination models

Magalon, K., Cantarella, C., Monti, G., Cayre, M., & Durbec, P. L. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05335.x · Cited by 82 · see citing works

Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12

Põlajeva, J., Sjösten, A., Lager, N., Kastemar, M., Waern, I., Alafuzoff, I. I., Smits, A., Westermark, B., Pejler, G., Uhrbom, L., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025222 · Cited by 81 · see citing works

Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

Sotthibundhu, A., Li, Q.-X., Thangnipon, W., & Coulson, E. J. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.02.004 · Cited by 81 · see citing works

SDF-1α Is Expressed in Astrocytes and Neurons in the AIDS Dementia Complex: An In Vivo and In Vitro Study

Rostasy, K. M., Egles, C., Chauhan, A., Kneissl, M., Bahrani, P., Yiannoutsos, C. T., Hunter, D. D., Nath, A., Hedreen, J. C., & NAVIA, B. A. (2003) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/62.6.617 · Cited by 79 · see citing works

Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease

Parachikova, A. I., & Cotman, C. W. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.07.001 · Cited by 77 · see citing works

SDF1α/CXCR4 Signaling, via ERKs and the Transcription Factor Egr1, Induces Expression of a 67-kDa Form of Glutamic Acid Decarboxylase in Embryonic Hippocampal Neurons

Luo, Y., Lathia, J. D., Mughal, M., & Mattson, M. P. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800649200 · Cited by 65 · see citing works

Expression of SDF-1 and CXCR4 during Reorganization of the Postnatal Dentate Gyrus

Berger, O., Li, G., Han, S.-M., Paredes, M. F., & Pleasure, S. J. (2006) · Developmental Neuroscience · doi:10.1159/000096210 · Cited by 65 · see citing works

Bone Marrow-Derived Mesenchymal Stem Cells Attenuate Amyloid β-Induced Memory Impairment and Apoptosis by Inhibiting Neuronal Cell Death

Lee, J. K., Jin, H. K., & Bae, J. (2010) · Current Alzheimer Research · doi:10.2174/156720510792231739 · Cited by 63 · see citing works

Presenilin 1 Mutants Impair the Self-Renewal and Differentiation of Adult Murine Subventricular Zone-Neuronal Progenitors via Cell-Autonomous Mechanisms Involving Notch Signaling

Veeraraghavalu, K., Choi, S. H., Zhang, X., & Sisodia, S. S. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0527-10.2010 · Cited by 61 · see citing works

Combined Effects of Hematopoietic Progenitor Cell Mobilization from Bone Marrow by Granulocyte Colony Stimulating Factor and AMD3100 and Chemotaxis into the Brain Using Stromal Cell‐Derived Factor‐1α in an Alzheimer's Disease Mouse Model

Shin, J., Lee, J. K., Lee, J. E., Min, W., Schuchman, E. H., Jin, H. K., & Bae, J. (2011) · Stem Cells · doi:10.1002/stem.659 · Cited by 57 · see citing works

Role of SDF1 chemokine in the development of lateral line efferent and facial motor neurons

Sapède, D., Rossel, M., Dambly‐Chaudière, C., & Ghysen, A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406382102 · Cited by 56 · see citing works

Alteration of CXCR7 Expression Mediated by TLR4 Promotes Tumor Cell Proliferation and Migration in Human Colorectal Carcinoma

Xu, H., Wu, Q., Dang, S., Jin, M., Xu, J., Cheng, Y., Pan, M., Wu, Y., Zhang, C., & Zhang, Y. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027399 · Cited by 55 · see citing works

Expression of the new CXCL12 receptor, CXCR7, in gliomas

Calatozzolo, C., Canazza, A., Pollo, B., et al. (2011) · Cancer Biology & Therapy · doi:10.4161/cbt.11.2.13951 · Cited by 51 · see citing works

Chemokine receptor CXCR4 signaling modulates the growth factor‐induced cell cycle of self‐renewing and multipotent neural progenitor cells

Li, M., Chang, C., Lathia, J. D., et al. (2010) · Glia · doi:10.1002/glia.21080 · Cited by 42 · see citing works

G Protein-Coupled Receptor Genes in the FANTOM2 DatabasePreprint

Kawasawa, Y. I., McKenzie, L. M., Hill, D. P., Bono, H. U., RIKEN GER Group, Members, G., & Yanagisawa, M. (2003) · Genome Research · doi:10.1101/gr.1087603 · Cited by 39 · see citing works

Role of Stromal-Derived Factor-1α in the Induction of Circulating CD34+CXCR4+ Progenitor Cells After Cardiac Surgery

Mieno, S., Ramlawi, B., Boodhwani, M., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.001610 · Cited by 37 · see citing works

Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero

Kubota, Y., Takubo, K., Hirashima, M., Nagoshi, N., Kishi, K., Okuno, Y., Nakamura‐Ishizu, A., Sano, K., Murakami, M., Ema, M., et al. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20102187 · Cited by 35 · see citing works

Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1α, suppress amyloid β-induced neurotoxicity

Raman, D., Milatovic, S., Milatović, D., Splittgerber, R. C., Fan, G.-H., & Richmond, A. J. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.06.006 · Cited by 31 · see citing works

Neural Stem Cells for CNS Transplantation

Baetge, E. E. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb23068.x · Cited by 27 · see citing works

Efficient Processing of Alzheimer's Disease Amyloid-Beta Peptides by Neuroectodermally Converted Mesenchymal Stem Cells

Habisch, H., Schmid, B., Arnim, C. A. F. V., Ludolph, A. C., Brenner, R. E., & Storch, A. (2009) · Stem Cells and Development · doi:10.1089/scd.2009.0045 · Cited by 23 · see citing works

The dynamic yin-yang interaction of CXCR4 and CXCR7 in breast cancer metastasis

Hawkins, O. E., & Richmond, A. J. (2012) · Breast Cancer Research · doi:10.1186/bcr3092 · Cited by 19 · see citing works

β-Amyloid42 Induces Desensitization of CXC Chemokine Receptor-4 via Formyl Peptide Receptor in Neural Stem/Progenitor Cells

Zhang, C. M., Wang, Z., Lok, K., & Yin, M. (2012) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.35.131 · Cited by 11 · see citing works

Single-cell transcriptomic profiling of the aging mouse brain

Ximerakis, M., Lipnick, S. L., Innes, B. T., Simmons, S. K., Adiconis, X., Dionne, D., Mayweather, B. A., Nguyen, L., Niziolek, Z., Ozek, C., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0491-3 · Cited by 736 · see citing works

Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axis

Asri, A., Sabour, J., Atashi, A., et al. (2016) · EXCLI journal · doi:10.17179/excli2014-585 · Cited by 47 · see citing works

Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot Study

Li, L., Wu, S., Liu, Z., et al. (2015) · Stem Cells International · doi:10.1155/2015/691310 · Cited by 53 · see citing works

Modulating the Interaction of Stromal-cell-derived Factor-1/CXCL12 and its Receptor, CXCR4, for Enhanced Mobilisation, Homing and Engraftment of Haematopoietic Stem Cells

Broxmeyer, H. E., & Campbell, T. (2007) · European Oncology & Haematology · doi:10.17925/eoh.2007.0.0.47 · Cited by 1 · see citing works

Injectable hydrogel delivery plus preconditioning of mesenchymal stem cells: exploitation of SDF‐1/CXCR4 axis toward enhancing the efficacy of stem cells' homing

Naderi‐Meshkin, H., Matin, M. M., Heirani‐Tabasi, A., Mirahmadi, M., Irfan‐Maqsood, M., Edalatmanesh, M. A., Shahriyari, M., Ahmadiankia, N., Moussavi, N. S., Bidkhori, H. R., et al. (2015) · Cell Biology International · doi:10.1002/cbin.10474 · Cited by 58 · see citing works

2020 - GPRASP FAMILY MEMBERS REGULATE MURINE HEMATOPOIETIC STEM CELL MIGRATION, HOMING AND NICHE RETENTION POST-TRANSPLANT VIA CONTROL OF CXCR4 STABILITY

Morales‐Hernández, A., Chabot, A., Ferdous, M., et al. (2019) · Experimental Hematology · doi:10.1016/j.exphem.2019.06.292