The role of inflammatory cytokines as key modulators of neurogenesis

From inflammation to sickness and depression: when the immune system subjugates the brain

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Astrocytes: Biology and pathology

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A Meta-Analysis of Cytokines in Major Depression

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Interferon-γ: an overview of signals, mechanisms and functions

Schroder, K., Hertzog, P. J., Ravasi, T., & Hume, D. A. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0603252 · Cited by 4,120

Mechanisms and Functional Implications of Adult Neurogenesis

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Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

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New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

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Proinflammatory Cytokines

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Dynamics of hippocampal neurogenesis in adult humans

Spalding, K. L., Bergmann, O., Alkass, K., Bernard, S., Salehpour, M., Huttner, H. B., Boström, E., Westerlund, I., Vial, C., Buchholz, B. A., et al. (2013) · Cell · doi:10.1016/j.cell.2013.05.002 · Cited by 1,841

Zika Virus Infects Intermediate Progenitor Cells and Post-mitotic Committed Neurons in Human Fetal Brain Tissues

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Mast cells in the brain – Old cells, new target

Traina, G. (2017) · Journal of Integrative Neuroscience · doi:10.3233/jin-170068 · Cited by 41

Deep brain stimulation of the anterior nucleus of the thalamus reverses the gene expression of cytokines and their receptors as well as neuronal degeneration in epileptic rats.

Chen, Y.-C., Zhu, G.-Y., Wang, X., Shi, L., Jiang, Y., Zhang, X., & Zhang, J.-G. (2017) · Brain Research · doi:10.1016/j.brainres.2016.12.020 · Cited by 36

To re-examine the intersection of microglial activation and neuroinflammation in neurodegenerative diseases from the perspective of pyroptosis

Li, Y., Li, Y., & Zhu, Z. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1284214 · Cited by 43

T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy

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Anti-inflammatory agents for smoking cessation? Focus on cognitive deficits associated with nicotine withdrawal in male mice

Saravia, R., Ten-Blanco, M., Grande, M. T., Maldonado, R. J., & Berrendero, F. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.11.003 · Cited by 39

Microglia Fighting for Neurological and Mental Health: On the Central Nervous System Frontline of COVID-19 Pandemic

de Andrade, E. G., Šimončičová, E., Carrier, M., Vecchiarelli, H. A., Robert, M.-È., & Tremblay, M. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.647378 · Cited by 39

Neuroscience, mental health and the immune system: overcoming the brain-mind-body trichotomy

Pariante, C. M. (2015) · Epidemiology and Psychiatric Sciences · doi:10.1017/s204579601500089x · Cited by 39

(Re)building the nervous system: A review of neuron–glia interactions from development to disease

Demmings, M. D., Chagas, L. D. S., Traetta, M. E., Rodrigues, R. S., Acutain, M. F., Barykin, E. P., Datusalia, A. K., German‐Castelan, L., Mattera, V. S., Mazengenya, P., et al. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16258 · Cited by 44

The Relationships between Damaging Behaviours and Health in Laying Hens

Michel, V., Berk, J., Bozakova, N., van der Eijk, J. A. J., Estévez, I., Mircheva, T., Relić, R., Rodenburg, T. B., Sossidou, E. Ν., & Guinebretière, M. (2022) · Animals · doi:10.3390/ani12080986 · Cited by 38

Trained innate immunity: a salient factor in the pathogenesis of neuroimmune psychiatric disorders

Salam, A. P., Borsini, A., & Zunszain, P. A. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.186 · Cited by 39

Autophagy alleviates ethanol-induced memory impairment in association with anti-apoptotic and anti-inflammatory pathways

Liu, Y., Zhang, Y., Peng, J., Wang, H., Li, X., Li, X., Rong, X., Pan, J., & Peng, Y. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.07.033 · Cited by 36

Methylphenidate Causes Behavioral Impairments and Neuron and Astrocyte Loss in the Hippocampus of Juvenile Rats

Schmitz, F., Pierozan, P., Rodrigues, A. F., Biasibetti, H., Grunevald, M., Pettenuzzo, L. F., Scaini, G., STRECK, E. L., Netto, C. A., & Wyse, Â. T. D. S. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9987-y · Cited by 38

The role of AQP4 in the pathogenesis of depression, and possible related mechanisms

Genel, O., Pariante, C. M., & Borsini, A. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.08.232 · Cited by 37

Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion

Hain, E. G., Sparenberg, M., Rasińska, J., Klein, C., Akyüz, L., & Steiner, B. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1179-4 · Cited by 36

Water-Soluble Arginyl–Diosgenin Analog Attenuates Hippocampal Neurogenesis Impairment Through Blocking Microglial Activation Underlying NF-κB and JNK MAPK Signaling in Adult Mice Challenged by LPS

Cai, B., Seong, K.-J., Bae, S., Kook, M. S., Chun, C., Lee, J. H., Choi, W., Jung, J., & Kim, W.-J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1496-3 · Cited by 37

Baseline serum C-reactive protein levels may predict antidepressant treatment responses in patients with major depressive disorder

Zhang, J., Yue, Y., Thapa, A., Fang, J., Zhao, S., Shi, W., Yang, Z. H., Li, Y., & Yuan, Y. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.03.001 · Cited by 36

RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways

Welleford, A. S., Quintero, J. E., Seblani, N. E., Blalock, E. M., Gunewardena, S., Shapiro, S. M., Riordan, S. M., Huettl, P. F., Guduru, Z., Stanford, J. A., et al. (2020) · Cell Transplantation · doi:10.1177/0963689720926157 · Cited by 35

Contributions of loneliness to cognitive impairment and dementia in older adults are independent of other risk factors and Alzheimer’s pathology: a narrative review

Oken, B., Kaplan, J., Klee, D., & Gallegos, A. M. (2024) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2024.1380002 · Cited by 39

(Putative) sex differences in neuroimmune modulation of memory

Tronson, N. C., & Collette, K. M. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23921 · Cited by 36

Neurotrophic, Cytoprotective, and Anti-inflammatory Effects of St. John's Wort Extract on Differentiated Mouse Hippocampal HT-22 Neurons

Bonaterra, G. A., Schwendler, A., Hüther, J., Schwarzbach, H., Schwarz, A., Kolb, C., Abdel-Aziz, H., & Kinscherf, R. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00955 · Cited by 34

Adult and endemic neurogenesis in the vestibular nuclei after unilateral vestibular neurectomy

Rastoldo, G., Mahmoudi, N. E., Marouane, E., Péricat, D., Watabe, I., Toneto, A., López‐Juárez, A., Chabbert, C., & Tighilet, B. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101899 · Cited by 34

Zebrafish: A New Promise to Study the Impact of Metabolic Disorders on the Brain

Ghaddar, B., & Diotel, N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105372 · Cited by 34

Neurodevelopmental disorders, immunity, and cancer are connected

Nussinov, R., Tsai, C., & Jang, H. (2022) · iScience · doi:10.1016/j.isci.2022.104492 · Cited by 35

Increased immune cell and altered microglia and neurogenesis transcripts in an Australian schizophrenia subgroup with elevated inflammation

North, H. F., Weissleder, C., Fullerton, J. M., Webster, M. J., & Weickert, C. S. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.08.025 · Cited by 34

Premarin has opposing effects on spatial learning, neural activation, and serum cytokine levels in middle-aged female rats depending on reproductive history

Galea, L. A. M., Roes, M., Dimech, C. J., Chow, C., Mahmoud, R., Lieblich, S. E., & Duarte‐Guterman, P. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.06.030 · Cited by 33

Insulin activates microglia and increases COX-2/IL-1β expression in young but not in aged hippocampus

Haas, C. B., de Carvalho, A. K., Muller, A. P., Eggen, B. J. L., & Portela, L. V. (2020) · Brain Research · doi:10.1016/j.brainres.2020.146884 · Cited by 37

A systematic, integrative review of the effects of the endocannabinoid system on inflammation and neurogenesis in animal models of affective disorders

Giacobbe, J., Marrocu, A., Benedetto, M. G. D., Pariante, C. M., & Borsini, A. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.12.024 · Cited by 36

Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes

Li, S.-J., Cao, W., Zhou, S.-F., Ma, M., Zhang, W., Fang, L., & Li, C.-Q. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.03.012 · Cited by 32

Inflammation biomarkers in suicide attempts and their relation to abuse, global functioning and cognition

Fernández-Sevillano, J., González–Ortega, I., MacDowell, K. S., Zorrilla, E. P., López, M. P., Courtet, P., Gabilondo, A., Martínez‐Cengotitabengoa, M., Leza, J. C., Sáiz, P. A., et al. (2021) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2021.1988703 · Cited by 37

L-methionine enhances neuroinflammation and impairs neurogenesis: Implication for Alzheimer's disease

Alachkar, A., Agrawal, S., Baboldashtian, M., Nuseir, K. Q., Salazar, J. V., & Agrawal, A. (2022) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2022.577843 · Cited by 38

The Secretome of Microglia Regulate Neural Stem Cell Function

Osman, A. M., Rodhe, J., Shen, X., Dominguez, C. A., Joseph, B., & Blomgren, K. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.10.034 · Cited by 33

Upregulation of peripheral CXC and CC chemokine receptor expression on CD4 + T cells is associated with immune dysregulation in children with autism

Ahmad, S. F., Ansari, M. A., Nadeem, A., Bakheet, S. A., AL-Ayadhi, L. Y., & Attia, S. M. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.10.001 · Cited by 32

Angiogenic response of rat hippocampal vasculature to focused ultrasound-mediated increases in blood-brain barrier permeability

McMahon, D., Mah, E., & Hynynen, K. (2018) · Scientific Reports · doi:10.1038/s41598-018-30825-8 · Cited by 34

Oxidative stress sensing and response in neural stem cell fate

Hwang, I., Tang, D., & Paik, J. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.03.043 · Cited by 33

The Role of Immune Factors in Shaping Fetal Neurodevelopment

Lu-Culligan, A., & Iwasaki, A. (2020) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-021120-033518 · Cited by 32

Maternal mid-gestational and child cord blood immune signatures are strongly associated with offspring risk of ASD

Che, X., Hornig, M., Bresnahan, M., Stoltenberg, C., Magnus, P. M., Surén, P., Mjaaland, S., Reichborn-Kjennerud, T., Susser, E., & Lipkin, W. I. (2022) · Molecular Psychiatry · doi:10.1038/s41380-021-01415-4 · Cited by 33

Inflammatory biomarkers and brain health indicators in children with overweight and obesity: The ActiveBrains project

Adelantado‐Renau, M., Esteban‐Cornejo, I., Rodríguez‐Ayllón, M., Cadenas‐Sánchez, C., Gil-Cosano, J. J., Mora-González, J., Solis‐Urra, P., Verdejo‐Román, J., Aguilera, C. M., Escolano-Margarit, M. V., et al. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.07.020 · Cited by 31

Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice

Li, X., Wang, H., Zhang, Q., Sun, X., Zhang, M., & Wang, G. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02910-x · Cited by 32

Chronic IL-10 overproduction disrupts microglia-neuron dialogue similar to aging, resulting in impaired hippocampal neurogenesis and spatial memory

Sanchez-Molina, P., Almolda, B., Giménez‐Llort, L., González, B., & Castellano, B. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.12.026 · Cited by 32

Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia

Xu, T., Li, X., Guo, Y., Uhlin, E., Holmberg, L., Mitra, S., Winn, D., Falk, A., & Sundström, E. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.103882 · Cited by 29

Adult Neurogenesis in Epileptogenesis: An Update for Preclinical Finding and Potential Clinical Translation

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Neuroprotective effects of Levisticum officinale on LPS-induced spatial learning and memory impairments through neurotrophic, anti-inflammatory, and antioxidant properties

Amraie, E., Pouraboli, I., & Rajaei, Z. (2020) · Food & Function · doi:10.1039/d0fo01030h · Cited by 29

Health Factors as Potential Mediators of the Longitudinal Effect of Loneliness on General Cognitive Ability

Kim, A. J., Beam, C. R., Greenberg, N. E., & Burke, S. L. (2020) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2020.07.017 · Cited by 33

Maternal behaviours and adult offspring behavioural deficits are predicted by maternal TNFα concentration in a rat model of neurodevelopmental disorders

Potter, H. G., Kowash, H. M., Woods, R. M., Revill, G., Grime, A., Deeney, B., Burgess, M. A., Aarons, T., Glazier, J. D., Neill, J. C., et al. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.12.003 · Cited by 33

Neuroinflammation and physical exercise as modulators of adult hippocampal neural precursor cell behavior

Pérez‐Domínguez, M., Tovar‐y‐Romo, L. B., & Zepeda, A. (2017) · Reviews in the Neurosciences · doi:10.1515/revneuro-2017-0024 · Cited by 29

Mapping secretome-mediated interaction between paired neuron–macrophage single cells

Deng, J., Ji, Y., Zhu, F., Liu, L., Li, L., Bai, X., Li, H., Liu, X., Luo, Y., Lin, B., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2200944119 · Cited by 26

The impact of maternal immune activation on embryonic brain development

McEwan, F., Glazier, J. D., & Hager, R. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1146710 · Cited by 30

Neuroprotective Activity of Evolvulus alsinoides & Centella asiatica Ethanolic Extracts in Scopolamine-Induced Amnesia in Swiss Albino Mice

Yadav, M. K., Singh, S. K., Singh, M., Mishra, S. S., Singh, A. K., Tripathi, J. S., & Tripathi, Y. B. (2019) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2019.247 · Cited by 26

Type 1 Interleukin-4 Signaling Obliterates Mouse Astroglia in vivo but Not in vitro

Mashkaryan, V., Siddiqui, T., Popova, S. D., Coşacak, M. İ., Bhattarai, P., Brandt, K., Govindarajan, N., Petzold, A., Reinhardt, S., Dahl, A., et al. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00114 · Cited by 27

Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study

Preez, A. D., Lefèvre‐Arbogast, S., González‐Domínguez, R., Houghton, V., de Lucia, C., Low, D. Y., Helmer, C., Féart, C., Delcourt, C., Proust‐Lima, C., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01644-1 · Cited by 27

Differentiation of stem cells derived from carious teeth into dopaminergic‐like cells

Gnanasegaran, N., Govindasamy, V., & Kasim, N. H. A. (2015) · International Endodontic Journal · doi:10.1111/iej.12545 · Cited by 26

Prolonged Periods of Social Isolation From Weaning Reduce the Anti-inflammatory Cytokine IL-10 in Blood and Brain

Zuelli, F. M. D. G. C., Fachim, H., Loureiro, C. M., Shuhama, R., Bertozi, G., Joca, S. R. L., Menezes, P. R., Louzada‐Júnior, P., & Del‐Ben, C. M. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.01011 · Cited by 25

The Impact of Diabetes Mellitus in COVID-19: A Mechanistic Review of Molecular Interactions

Yaribeygi, H., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2020) · Journal of Diabetes Research · doi:10.1155/2020/5436832 · Cited by 29

A chicken and egg scenario in psychoneuroimmunology: Bidirectional mechanisms linking cytokines and depression

Rengasamy, M. L., Marsland, A. L., Spada, M. L., Hsiung, K. S., Kovats, T., & Price, R. B. (2021) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2021.100177 · Cited by 29

MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling

Lin, K., Bieri, G., Gontier, G., Müller, S., Smith, L. K., Snethlage, C. E., White, C. W., Maybury‐Lewis, S. Y., & Villeda, S. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001311 · Cited by 26

Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer’s disease neuropathology

Agrawal, S., Baulch, J. E., Madan, S., Salah, S., Cheeks, S. N., Krattli, R. P., Subramanian, V. S., Acharya, M. M., & Agrawal, A. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04347-6 · Cited by 25

SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders

Dubey, H., Sharma, R. K., Krishnan, S., & Knickmeyer, R. C. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1021721 · Cited by 27

Defining the Relationship of Gut Microbiota, Immunity, and Cognition in Early Life—A Narrative Review

Kartjito, M. S., Yosia, M., Wasito, E., Soloan, G., Agussalim, A. A. K., & Basrowi, R. W. (2023) · Nutrients · doi:10.3390/nu15122642 · Cited by 34

Low intensity, long term exposure to tobacco smoke inhibits hippocampal neurogenesis in adult mice

Csabai, D., Csekő, K., Szaiff, L., Varga, Z., Miseta, A., Helyes, Z., & Czéh, B. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.01.022 · Cited by 27

Novel targets for parkinsonism-depression comorbidity

Tizabi, Y., Getachew, B., Csoka, A. B., Manaye, K. F., & Copeland, R. (2019) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2019.06.004 · Cited by 25

IL-1 reprogramming of adult neural stem cells limits neurocognitive recovery after viral encephalitis by maintaining a proinflammatory state

Soung, A., Davé, V. A., Garber, C., Tycksen, E., Vollmer, L. L., & Klein, R. S. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.10.010 · Cited by 22

Zika virus-induced TNF-α signaling dysregulates expression of neurologic genes associated with psychiatric disorders

Kung, P.-L., Chou, T.-W., Lindman, M., Chang, N. P., Estevez, I., Buckley, B. D., Atkins, C., & Daniels, B. P. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02460-8 · Cited by 25

Astroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus

Tao, Y., Ma, L., Liao, Z., Le, Q., Yu, J., Liu, X., Li, H., Chen, Y., Zheng, P., Yang, Z., et al. (2015) · Scientific Reports · doi:10.1038/srep15506 · Cited by 26

Screening and Isolation of Potential Anti-Inflammatory Compounds from Saxifraga atrata via Affinity Ultrafiltration-HPLC and Multi-Target Molecular Docking Analyses

Li, G., Fang, Y., Ma, Y., Dawa, Y., Wang, Q., Gan, J., & Dang, J. (2022) · Nutrients · doi:10.3390/nu14122405 · Cited by 23

Maternal immune activation in rats induces dysfunction of placental leucine transport and alters fetal brain growth

Kowash, H. M., Potter, H. G., Woods, R. M., Ashton, N., Hager, R., Neill, J. C., & Glazier, J. D. (2022) · Clinical Science · doi:10.1042/cs20220245 · Cited by 23

Where Do Epigenetics and Developmental Origins Take the Field of Developmental Psychopathology?

Nigg, J. T. (2016) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-015-0121-9 · Cited by 24

Important unanswered questions about adult neurogenesis in schizophrenia

Weissleder, C., North, H. F., & Weickert, C. S. (2019) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000501 · Cited by 22

Distinctive cytokine profiles of stem cells from human exfoliated deciduous teeth and dental pulp stem cells

Kang, C., Shin, M. K., Jeon, M., Lee, Y.-H., Song, J. S., & Lee, J. H. (2021) · Journal of Dental Sciences · doi:10.1016/j.jds.2021.03.019 · Cited by 22

Familial co-aggregation of attention-deficit/hyperactivity disorder and autoimmune diseases: a cohort study based on Swedish population-wide registers

Hegvik, T., Chen, Q., Kuja‐Halkola, R., Klungsøyr, K., Butwicka, A., Lichtenstein, P., Almqvist, C., Faraone, S. V., Haavik, J., & Larsson, H. (2021) · International Journal of Epidemiology · doi:10.1093/ije/dyab151 · Cited by 25

Therapeutic implication of Sonic Hedgehog as a potential modulator in ischemic injury

Mohan, M., Mannan, A., & Singh, T. G. (2023) · Pharmacological Reports · doi:10.1007/s43440-023-00505-0 · Cited by 22

Neuroendocrine Abnormalities in Major Depression: An Insight Into Glucocorticoids, Cytokines, and the Kynurenine Pathway

Nikkheslat, N., Pariante, C. M., & Zunszain, P. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811073-7.00003-9 · Cited by 23

Physiological Interactions between Microglia and Neural Stem Cells in the Adult Subependymal Niche

Sirerol-Piquer, M. S., Belenguer, G., Morante‐Redolat, J. M., Duart-Abadía, P., Pérez‐Villalba, A., & Fariñas, I. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.01.009 · Cited by 23

The role of microglia in the second and third postnatal weeks of life in rat hippocampal development and memory

Soch, A., Sominsky, L., Younesi, S., Luca, S. N. D., Gunasekara, M., Bozinovski, S., & Spencer, S. J. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.04.082 · Cited by 21

Inflammation and Cognition in Children and Adolescents: A Call for Action

Adelantado‐Renau, M., Beltran‐Valls, M. R., & Moliner‐Urdiales, D. (2020) · Frontiers in Pediatrics · doi:10.3389/fped.2020.00583 · Cited by 20

Microglial FABP4-UCP2 Axis Modulates Neuroinflammation and Cognitive Decline in Obese Mice

So, S. W., Fleming, K. M., Duffy, C. M., Nixon, J. P., Bernlohr, D., & Butterick, T. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084354 · Cited by 21

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders

Chen, L., Li, Z., Wang, W., Zhou, Y., Li, W., & Wang, Y. (2025) · Stem Cell Reports · doi:10.1016/j.stemcr.2025.102600 · Cited by 25

Neonatal kaempferol exposure attenuates impact of cerebral palsy model on neuromotor development, cell proliferation, microglia activation, and antioxidant enzyme expression in the hippocampus of rats

Visco, D. B., Manhães‐de‐Castro, R., da Silva, M. M., de Santana, B. J. R. C., dos Santos, J. P., Saavedra, L. M., de Lemos, M. D. T. B., Valdez-Alarcón, J. J., Lagranha, C. J., Guzmán‐Quevedo, O., et al. (2022) · Nutritional Neuroscience · doi:10.1080/1028415x.2022.2156034 · Cited by 20

The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture of polychlorinated biphenyls

Matelski, L., Keil, K. P., Sethi, S., Taylor, S. L., de Water, J. V., & Lein, P. J. (2020) · Current Research in Toxicology · doi:10.1016/j.crtox.2020.09.001 · Cited by 20

Emerging Pro-neurogenic Therapeutic Strategies for Neurodegenerative Diseases: A Review of Pre-clinical and Clinical Research

Vassal, M., Martins, F., Monteiro, B., Tambaro, S., Martínez‐Murillo, R., & Rebelo, S. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04246-w · Cited by 24

Atorvastatin ameliorates viral burden and neural stem/progenitor cell (NSPC) death in an experimental model of Japanese encephalitis

Wani, M. A., Mukherjee, S., Mallick, S., Akbar, I., & Basu, A. (2020) · Journal of Biosciences · doi:10.1007/s12038-020-00052-3 · Cited by 20

Implications for microglial sex differences in tau-related neurodegenerative diseases

Doust, Y. V., King, A. E., & Ziebell, J. M. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.03.010 · Cited by 18

Interleukin-6 promotes microtubule stability in axons via Stat3 protein–protein interactions

Wareham, L. K., Echevarría, F. D., Sousa, J. L., Konlian, D. O., Dallas, G., Formichella, C. R., Sankaran, P., Goralski, P. J., Gustafson, J. R., & Sappington, R. M. (2021) · iScience · doi:10.1016/j.isci.2021.103141 · Cited by 17

Breaking free from the inflammatory trap of depression: Regulating the interplay between immune activation and plasticity to foster mental health

Branchi, I., Viglione, A., Vai, B., Cirulli, F., Benedetti, F., & Poggini, S. (2023) · Neuroscience Applied · doi:10.1016/j.nsa.2023.103923 · Cited by 18

Inflammasome signaling in astrocytes modulates hippocampal plasticity

Zengeler, K. E., Hollis, A., Deutsch, T. C. J., Samuels, J. D., Ennerfelt, H. E., Moore, K. A., Steacy, E. J., Sabapathy, V., Sharma, R., Patel, M. K., et al. (2025) · Immunity · doi:10.1016/j.immuni.2025.04.007 · Cited by 23

Developmental immune activation programs adult behavior: insight from research on birds

Grindstaff, J. L. (2015) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2015.10.006 · Cited by 18

Parenchymal and non‐parenchymal immune cells in the brain: A critical role in regulating CNS functions

Arcuri, C., Mecca, C., Giambanco, I., & Donato, R. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.04.005 · Cited by 19

The innate immune system and neurogenesis as modulating mechanisms of electroconvulsive therapy in pre-clinical studies

Giacobbe, J., Pariante, C. M., & Borsini, A. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120936538 · Cited by 20

The role of plasma inflammatory markers in late-life depression and conversion to dementia: a 3-year follow-up study

Bocharova, M., Borza, T., Watne, L. O., Engedal, K., O'Brien, J. T., Selbæk, G., Idland, A., Hodsoll, J. P., Young, A. H., & Aarsland, D. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02908-2 · Cited by 19

Inflammation and Late-Life Depression: Unraveling the Complex Relationship and Potential Therapeutic Strategies

Xia, J., Chen, M., Shao, H., Chen, H., Zhu, S., Zhao, M., Luo, W., Yang, J., & Wu, S. (2023) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2812356 · Cited by 17

In Amyotrophic Lateral Sclerosis Blood Cytokines Are Altered, but Do Not Correlate with Changes in Brain Topology

Polverino, A., Rucco, R., Stillitano, I., Bonavita, S., Grimaldi, M., Minino, R., Pesoli, M., Trojsi, F., D’Ursi, A. M., Sorrentino, G., et al. (2020) · Brain Connectivity · doi:10.1089/brain.2020.0741 · Cited by 18

Experimental Arthritis Inhibits Adult Hippocampal Neurogenesis in Mice

Rusznák, K., Horváth, Á. I., Pohli-Tóth, K., Futácsi, A., Kemény, Á., Kiss, G., Helyes, Z., & Czéh, B. (2022) · Cells · doi:10.3390/cells11050791 · Cited by 16

Microglial Dynamics Modulate Vestibular Compensation in a Rodent Model of Vestibulopathy and Condition the Expression of Plasticity Mechanisms in the Deafferented Vestibular Nuclei

Mahmoudi, N. E., Marouane, E., Rastoldo, G., Péricat, D., Watabe, I., Lapôtre, A., Tonetto, A., Chabbert, C., & Tighilet, B. (2022) · Cells · doi:10.3390/cells11172693 · Cited by 16

Stem Cells in Neuroendocrinology

Pfaff, D., & Christen, Y. (2016) · Research and perspectives in endocrine interactions · doi:10.1007/978-3-319-41603-8 · Cited by 16

Translational Functional Neuroimaging in the Explanation of Depression

Stoyanov, D., Kandilarova, S., & Borgwardt, S. (2017) · Balkan Medical Journal · doi:10.4274/balkanmedj.2017.1160 · Cited by 16

Tumor necrosis factor‐alpha −1031T/C polymorphism is associated with cognitive deficits in chronic schizophrenia patients versus healthy controls

Xiu, M. H., Man, L., Wang, D., Du, X., Yin, G., Zhang, Y., Tan, Y., Chen, N., Chen, S., Teixeira, A. L., et al. (2018) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32622 · Cited by 16

The role of soluble epoxide hydrolase and its inhibitors in depression

Borsini, A. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100325 · Cited by 16

Neuroinflammation and excitatory symptoms in bipolar disorder

Sani, G., Panaccione, I., & Spalletta, G. (2015) · Neuroimmunology and Neuroinflammation · doi:10.4103/2347-8659.167304 · Cited by 17

Translational Significance of Selective Estrogen Receptor Modulators in Psychiatric Disorders

Khan, M. M. (2018) · International Journal of Endocrinology · doi:10.1155/2018/9516592 · Cited by 16

Microglia signaling in health and disease – Implications in sex-specific brain development and plasticity

Pramanik, S., Harini Devi, M., Chakrabarty, S., Paylar, B., Pradhan, A., Thaker, M., Ayyadhury, S., Manavalan, A., Olsson, P., Pramanik, G., et al. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105834 · Cited by 18

P.1.20 Medial forebrain bundle stimulation induces changes in dopamine neuron activity: role of endocannabinoids and glutamate

Pillolla, G., Perra, S., Melis, M., Muntoni, A. L., & Pistis, M. (2007) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(07)70021-4

Cytokine dysregulation and hippocampal neurogenesis: A shared mechanism underlying cognitive impairments across neuropsychiatric and neurodegenerative disorders

Tukiran, N., Kolb, T., Maggioni, L., Rai, S., Rafath, Z., & Borsini, A. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.107069

Neurogenesis, Inflammation, and Mental Health

Borsini, A., Sawyer, K. M., Zunszain, P. A., & Pariante, C. M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811073-7.00006-4 · Cited by 1

Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders

Whitney, N. P., Eidem, T. M., Peng, H., Huang, Y., & Zheng, J. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05886.x · Cited by 384

Neurogenesis, inflammation and behavior

Kohman, R. A., & Rhodes, J. S. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.09.003 · Cited by 380