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Lysosomal Dysfunction at the Centre of Parkinson’s Disease and Frontotemporal Dementia/Amyotrophic Lateral Sclerosis

Wallings, Rebecca L., Humble, Stewart W., Ward, Michael E., Wade-Martins, Richard·2019·Trends in Neurosciences
DOI 10.1016/j.tins.2019.10.002PMC PMC6931156
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  • Lysosomal function is vital for the proper function and survival of post-mitotic neurons.

    “Their function is vital for the proper function and survival of post-mitotic neurons, and, not surprisingly, dysregulation of lysosomal degradative pathways is linked to various neurodegenerative disorders (Wallings et al., 2019;Wang et al., 2018).”

    From TMEM55B promotes anterograde transport and distal axonal distribution of LAMP1-positive organelles (2026) · cites this paper as Wallings et al., 2019

  • Dysregulation of lysosomal degradative pathways is linked to various neurodegenerative disorders.

    “Their function is vital for the proper function and survival of post-mitotic neurons, and, not surprisingly, dysregulation of lysosomal degradative pathways is linked to various neurodegenerative disorders (Wallings et al., 2019;Wang et al., 2018).”

    From TMEM55B promotes anterograde transport and distal axonal distribution of LAMP1-positive organelles (2026) · cites this paper as Wallings et al., 2019

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Research works printed but not linked: 91

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Cited by

Sorted by citations

Metadata

Authors
Wallings, R. L., Humble, S. W., Ward, M. E., & Wade-Martins, R.
Venue
Trends in Neurosciences
Publisher
Elsevier BV
Published
2019-12
Volume
42
Issue
12
Pages
899-912
ISSN
0166-2236
DOI
10.1016/j.tins.2019.10.002
PMC
PMC6931156
Cited by
153
References
18
Language
en
Licence
Funders
  • National Institute of Neurological Disorders and Stroke
  • Parkinson's UK

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