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IGF2 in memory, neurodevelopmental disorders, and neurodegenerative diseases
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“IGF2R is important for memory, and its dysregulation may contribute to AD pathology. IGF2R levels decrease with the presence of the APOE4 allele, which is associated with increased risk for AD and overexpression of IGF2R is also associated to increase Aβ production [51, 52].”
From Impact of zervimesine on the neuroinflammatory biomarker GFAP and related proteomic molecular correlates in plasma of participants from a phase 2 clinical trial in Alzheimer’s disease (2026) · cites this paper as [51]
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Di Caro, V., Cho, E., Thiel, J., Lizama, B. N., Koel-Simmelink, M. J. A., Pandey, K., Duong, D., Seyfried, N. T., Grundman, M., Teunissen, C. E., et al. (2026) · Alzheimer's Research & Therapy · doi:10.1186/s13195-026-02025-4 · Cited by 1
Metadata
- Authors
- Alberini, C. M.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 2023-06
- Volume
- 46
- Issue
- 6
- Pages
- 488-502
- ISSN
- 0166-2236
- PMC
- PMC10192130
- Cited by
- 89
- References
- 4
- Language
- en
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- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 350 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
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